CT、MRI在视网膜母细胞瘤的诊断价值

目的:探讨视网膜母细胞瘤的CT和MRI表现及其在诊断与鉴别诊断中的价值.方法:回顾性分析经病理证实的27例视网膜母细胞瘤的CT及MRI表现,所有病例均行CT检查,9例行MRI检查.结果:CT显示眼球内软组织肿块21例,其中眼球内单发肿块14例,多发肿块7例;肿块突破眼环进入球外5例,视神经增粗2例;颅内侵犯1例;视网膜脱离1例;伴钙化24例.MRI显示眼球内肿块5例;眼球内外肿块3例,视神经增粗3例;沿视神经侵犯颅内1例;伴视网膜脱离2例;钙化灶4例.结论:CT对视网膜母细胞瘤的定性诊断有重要意义,MRI对视网膜母细胞瘤的分期及显示视网膜脱离较好.     

视网膜母细胞瘤的CT诊断价值

目的 分析视网膜母细胞瘤的CT表现,进一步认识CT在其诊断中的应用价值。资料与方法 回顾性分析9例经手术病理或随访证实的视网膜母细胞瘤临床和CT资料。结果 9例患儿均可见眼球后部实质肿块：8例伴有钙化,其中团片状钙化6例,斑点状钙化2例;眼球突出5例,视神经增粗2例,颅内侵犯1例。结论 CT对视网膜母细胞瘤的诊断、分期、手术及判断预后提供了客观依据。     

视网膜母细胞瘤的CT诊断

目的:探讨视网膜母细胞瘤的CT表现特征。方法:回顾分析 51 例经手术病理证实的视网膜母细胞瘤。术前均采用层厚、层距为 2~3 mm的 CT轴位扫描。10 例行增强扫描,对比剂用量为 1.5 ml/kg,注射流率为 1.5 ml/s。结果:CT发现51例中单眼发病48例,双眼发病3例;48例表现为眼球内肿块伴钙化,眼球增大26例,眼环受累12 例,视网膜脱离9例。视神经增粗16例,眶内侵犯2例,眶周侵犯 2 例,颅内侵犯 3 例。病理学检查 18 例视神经受累。结论:CT是诊断视网膜母细胞瘤的重要工具。对其可做出定位和定性诊断,并可进行准确分期。     

视网膜母细胞瘤的CT诊断

目的 探讨视网膜母细胞瘤的CT特征、诊断和鉴别诊断。方法 回顾性分析31例（32只眼）资料完整经病理或临床证实的视网膜母细胞瘤临床和CT检查资料。结果 视网膜母细胞瘤的典型临床表现为白瞳、眼球突出等，CT表现为：a）眼球后部软组织肿块．b）点状、斑片状钙化，钙化率93.8％；c）眼球突出；d）视神经增粗，眼环增厚，提示球外蔓延。结论 CT对视网膜母细胞瘤的诊断及分期有重要价值，瘤体内钙化斑是视网膜母细胞瘤的特征性CT表现。     

眼球内肿瘤的CT表现

目的：探讨常见眼球内肿瘤的CT表现及其在诊断与鉴别诊断中的价值。方法：分析经手术病理证实的47例眼球内肿瘤的CT表现,其中平扫47例、平扫加增强扫描37例。结果：视网膜母细胞瘤29例,CT表现自眼环生长的软组织肿块并钙化为本病特征表现,葡萄膜黑色素瘤13例,脉络膜血管瘤1例,脉络膜转移瘤2例,CT均表现起自眼环的软组织肿块,无钙化;脉络膜骨瘤2例,CT表现眼环类圆形骨密度肿瘤。结论：CT可确定眼球内肿瘤的位置并提示肿瘤的性质,对视网膜母细胞瘤进行确切的诊断及分期,为临床制定治疗方案提供依据。     

视网膜母细胞瘤的CT与MRI诊断

目的:探讨CT与MRI对视网膜母细胞瘤的诊断价值。方法:16例视网膜母细胞瘤,11例行CT检查,4例行MRI检查,1例同时行CT和MRI检查。回顾性分析其影像学征像。结果:视网膜母细胞瘤的CT征象主要表现为眼环后份或以后份为主的软组织肿块,伴有斑点及斑块状钙化,钙化显示率达92.9%(13/14)。MRI主要表现为眼环内软组织信号肿块,部分病例肿块内可见更低信号影,钙化显示率仅40%(2/5),但MRI对肿瘤侵犯周围结构较敏感。结论:CT与MRI对视网膜母细胞瘤的诊断价值,以CT较具优势,肿块内钙化可以认为是视网膜母细胞瘤定性诊断依据。影像学检查对于临床确定治疗方案和判断预后具有重要临床价值。     

视网膜母细胞瘤的CT诊断

目的:探讨视网膜母细胞瘤CT表现及其特征。材料和方法:回顾性分析11例经临床和手术病理证实的视网膜母细胞瘤的CT表现。结果:视网膜母细胞瘤CT表现为眼球后壁软组织肿块11例,其中肿块内有钙化9例,玻璃体密度增高8例,突眼6例,视神经增粗4例,颅内侵犯和转移2例。术前定性准确率为81．8％,分期准确率为73％。结论:视网膜母细胞瘤的CT表现具有特征性,CT检查对本病具有重要价值。     

视网膜母细胞瘤的多层螺旋CT诊断

目的:探讨多层螺旋CT(MSCT)在视网膜母细胞瘤(Rb)诊断中的价值.方法:回顾性分析10例视网膜母细胞瘤的MSCT表现特点.结果:视网膜母细胞瘤MSCT表现为眼球后半部实质性肿块10例,肿块内有钙化9例,玻璃体密度增高3例,视神经增粗3例,颅内侵犯和转移1例.结论:视网膜母细胞瘤的MSCT表现具有特征性,增强检查对未钙化病例具有诊断意义.     

视网膜母细胞瘤的影像学表现及其临床价值

目的　探讨视网膜母细胞瘤的CT、MRI表现及其诊断、鉴别诊断价值。方法　回顾性分析 3 2例经手术病理 (2 9例 )和临床证实 (3例 )的视网膜母细胞瘤。所有病例均行CT检查 ,11例行MRI检查。结果　具有典型CT表现者 2 8例 :①眼球壁上软组织密度块影向球内隆起 ;②斑点状或团块状钙化。 3例视神经增粗 ,其中 1例伴鞍上肿块。 4例瘤内无钙化。MRI显示 11例球内肿块同时伴有视网膜下积液、出血 2例 ,显示有低信号钙化灶 2例 ,视神经增粗 2例。CT与MRI检查对视网膜母细胞瘤敏感性相同。定性诊断准确率 :CT 90 .63 % (2 9/3 2 ) ,MRI 81.82 % (9/11)。分期准确率 :CT 93 .10 % (2 7/2 9) ,MRI 10 0 % (9/9)。结论　CT对肿瘤定性诊断具有重要意义。MRI检查对肿瘤分期较优越。对无钙化肿瘤辅以MRI检查可提高定性诊断准确率     

视网膜母细胞瘤和Coat’s病CT征象的研究

目的：本文旨在探讨视网膜母细胞瘤与Coat’s病的不同CT表现，提高诊断和鉴别诊断能力。材料和方法：12例视网膜母细胞瘤和5例Coat’s病经手术病理证实，均在术前接受CT检查。CT为2毫米层厚连续扫描，并给予团注法增强检查。结果：两者均有软组织肿块和玻璃体密度增高．但视网膜母细胞瘤除绝大多数有钙化外．还有眼球增大，晶状体密度减低和移位的表现。结论：多数情况下．根据有无钙化可将两者区别开来．少数无钙化视网膜母细胞瘤还需根据眼球大小和晶体状改变加以区别。     

Retinoblastoma: CT and MRI

To evaluate the effectiveness of CT and MRI at 0.5 T in the diagnosis and staging of retinoblastoma, we studied 11 patients in whom retinoblastoma was clinically suspected. Nine of the eleven had surgically proven retinoblastoma; in the other two a diagnosis of Coat's disease was made. MRI was not as specific as CT for diagnosing retinoblastoma, due to its lack of sensitivity in detecting calcification; it did, however, have superior contrast resolution. On MRI, Coats' discase was reliably diagnosed and easily differentiated from retinoblastoma. Moreover, the greater ability of MRI to differentiate subretinal fluid from tumour also confers high accuracy in measuring tumour size. CT is still the study of choice in the diagnosis of retinoblastoma, but when MRI is available, it should be performed for better differentiation from lesions such as Coats' disease.     

Retinoblastoma and simulating lesions: role of CT and MR imaging

Diagnosis of retinoblastoma is one of the most challenging problems of pediatric ophthalmology and radiology. It must be differentiated from numerous simulating lesions. Accurate diagnosis by means of ultrasonography, CT, and MR is essential for prompt treatment and prevention of metastasis. The CT and MR findings in 45 patients are presented in this article in order to evaluate and compare the usefulness of these two imaging techniques in the diagnosis of retinoblastoma.     

Sonographic, CT, and MR imaging findings in diffuse infiltrative retinoblastoma: report of two cases with histologic comparison

SUMMARY: Diffuse infiltrating retinoblastoma is a rare form of retinoblastoma. We report two cases of this disease in which sonographic, CT, and MR imaging findings were compared with histologic studies obtained after enucleation. Although nonspecific, MR imaging provides valuable morphologic data for the diagnosis of diffuse infiltrating retinoblastoma and may help in decisions regarding enucleation.     

Trilateral retinoblastoma: clinical and radiologic progression

OBJECTIVE: The purpose of this study was to assess the clinical and radiologic features of tumor progression in children with trilateral retinoblastoma. MATERIALS AND METHODS: Clinical records of eight children with trilateral retinoblastoma were reviewed for the patient's age at the time of diagnosis of the ocular tumor, time interval from diagnosis of ocular retinoblastoma to discovery of the intracranial tumor, time interval from diagnosis of retinoblastoma to death, and time interval from diagnosis of the intracranial tumor to death. CT or MRI studies were reviewed for the appearance of the primary intracranial neoplasm, intracranial metastases, and spinal metastases. RESULTS: The mean age of the patients at diagnosis of bilateral retinoblastoma was 4.5 months, and the mean age at diagnosis of the intracranial midline tumor was 26 months. The mean interval from the time of diagnosis of retinoblastoma to discovery of the intracranial tumor was 21.5 months. Two children had spinal leptomeningeal metastases at the time of discovery of the midline intracranial mass although no intracranial metastases were seen on imaging. In the other children, intracranial and spinal leptomeningeal metastases frequently developed within months of the diagnosis of retinoblastoma despite lack of progression in the midline intracranial lesion. Six children died of leptomeningeal spread of tumor. The mean interval from diagnosis of the ocular tumor to death was 46 months and from diagnosis of the intracranial tumor to death was 17 months. One child developed metastatic retinoblastoma in the ulna 10 years after the diagnosis of the intracranial tumor. CONCLUSION: Children typically died of leptomeningeal tumor dissemination despite lack of progression in the midline intracranial mass. Effective treatment of trilateral retinoblastoma may require close evaluation of these children for leptomeningeal dissemination.     

眼球肿瘤的CT诊断

本文回顾性分析了经手术病理证实的8例视网膜母细胞瘤和5例脉络膜黑色素瘤的临床资料及CT表现。CT图像上,前者表现为球内高密度肿块、钙斑及球外侵犯,后者表现为眼球后部肿块,多具有明显强化。为了进行鉴别诊断,附加1例曾误诊为视网膜母细胞瘤后经病理证实的Coat's病,并对两者的CT鉴别进行了初步探讨。