鼻唇沟螺旋桨皮瓣在面部皮肤软组织缺损中的应用

目的探讨鼻唇沟螺旋桨皮瓣在面部皮肤软组织缺损修复重建中的应用。方法选取2012年1月~2015年1月于台山市人民医院就诊因肿瘤、创伤等原因导致的面部软组织损伤患者34例,其中男性23例,女性11例;年龄29~67岁,平均47岁。平均面部缺损面积2.0cm×3.0cm;缺损部位包括面部、鼻部、唇部、脸颊部,采用鼻唇沟螺旋桨皮瓣进行修复重建。术后随访6个月,观察患者术后情况及皮瓣成活情况,同时记录患者术后并发症情况。结果 34例患者均一期愈合。随访期间30例患者肿瘤未见复发,皮瓣生存良好,成活率达97.1%;皮瓣色泽与周围组织基本一致,无面瘫、鼻通气功能及咀嚼功能障碍,外观形态满意,总体满意度达到91.2%,无严重手术并发症的发生。结论鼻唇沟螺旋桨皮瓣修复面部软组织缺损疗效好,满意度高,值得推广应用。     

SMAS蒂皮瓣在面部软组织缺损修复中的应用

目的探讨应用SMAS蒂皮瓣修复面部软组织缺损的临床经验。方法对112例各种原因造成的面部软组织缺损创面采用SMAS蒂皮瓣进行修复。结果术后72h内,皮瓣可能出现局部皮下淤血、轻度水肿等轻度静脉回流障碍,1周内均可自行恢复。所有病例皮瓣成活良好,修复后功能及外形满意,瘢痕不明显。结论只要设计合理,供区条件良好,SMAS蒂皮瓣修复面部软组织缺损是一种效果优良、安全可靠的方法。     

临近皮瓣修复头面部恶性肿瘤术后皮肤缺损疗效分析

目的　探讨头面部恶性肿瘤切除后皮肤缺损的修复原则和术式选择。方法　对30 例头面部基底细胞癌, 15 例鳞状细胞癌实行肿瘤切除术, 术区皮肤缺损创面应用临近皮瓣修复治疗, 观察并分析其治疗效果。结果　45 例移植皮瓣全部成活, 切口一期愈合; 随访3 个月至2 年, 修复皮肤平整, 肤色正常, 未出现切缘瘢痕, 效果满意, 无复发病例。结论　邻近皮瓣修复头面部皮肤恶性肿瘤切除术后缺损创面疗效满意, 皮肤色泽、厚度及柔软度与受区相似。     

局部旋转皮瓣修复小腿软组织缺损

应用局部旋转皮瓣修复18例小腿软组织缺损，缺损面积2cm ×2cm～6cm ×3．5cm。术后18例皮瓣均存活，切口Ⅰ期愈合，皮瓣外形美观，修复缺损满意。     

机械磨削联合湿润烧伤膏治疗面部痤疮瘢痕疗效分析

【摘要】 目的 分析机械磨削联合湿润烧伤膏在面部痤疮瘢痕中的治疗效果。方法 给予 2019 年 5 月至2021 年 5 月滨州医学院附属医院收治的 22 例面部痤疮瘢痕患者于机械磨削术后行湿润烧伤膏治疗, 观察治疗效果。结果 22 例面部痤疮瘢痕患者术后创面愈合时间为 5 ~ 8 d [ ( 6.27± 1.08) d]。术后 6 个月, 22 例患者Goodman & Baron 痤疮瘢痕评分为 7~ 21 分 [ (14.32±4.82) 分], 较术前的 13~ 30 分 [ (20.91±5.13) 分] 降低2~ 12 分 [ (6.59±2.42) 分], 差异具有统计学意义 (t = 4.391, P<0.001)。术后 6 个月, 22患者中 2 例患者术区有不同程度色素沉着, 其余患者无不良反应发生; 对治疗效果非常满意 8 例、满意 10 例、不满意 3 例、非常不满意 1 例, 满意度为 81.82%。结论 湿润烧伤膏可有效促进机械磨削术后创面愈合, 明显改善面部痤疮瘢痕症状, 且安全有效, 患者满意度较高, 值得临床推广应用。     

皮下蒂鼻唇沟皮瓣在面部急诊外伤修复中的应用

以皮下蒂的鼻唇沟皮瓣修复面部外伤所致的中小范围皮肤软组织缺损共47处,术后瘢痕不明显,局部平整,没有明显皮肤色差,无继发畸形,达到了面部外伤缺损即时整形的效果。     

瘢痕断层皮片联合人工真皮在关节部位烧伤瘢痕整复中的可行性分析

目的探讨瘢痕断层皮片联合人工真皮在关节部位烧伤瘢痕整复中的可行性。方法选取2010年1月至2018年1月东莞市人民医院烧伤整形外科收治的40例关节部位烧伤后出现瘢痕增生的患者作为研究对象,并按照随机数表法将其随机分为研究组(20例)与对照组(20例),其中研究组患者采用瘢痕断层皮片联合人工真皮修复关节部位瘢痕,对照组患者单纯采用瘢痕断层皮片修复关节部位瘢痕,对比观察两组患者术后创面Ⅰ级愈合率、温哥华瘢痕量表(Vancouver scar scale,VSS)评分、关节活动度(range of motion,ROM)评分,评估瘢痕修复效果。结果术后随访6个月,研究组患者的创面Ⅰ级愈合率为85.0%,明显高于对照组患者的创面Ⅰ级愈合率55.0%,P0.05,差异具有统计学意义;治疗后6个月,研究组患者的VSS评分为(3.1±0.4)分,明显低于对照组患者的VSS评分(5.7±1.1)分,P0.05,差异具有统计学意义;治疗后6个月,研究组患者的ROM评分为(90.8±4.5)分,明显高于对照组患者的ROM评分(79.9±7.6)分,P0.05,差异具有统计学意义。结论瘢痕断层皮片联合人工真皮移植可促进关节部位烧伤瘢痕整复患者术后创面Ⅰ级愈合,降低瘢痕增生程度,提高关节活动度,在关节部位烧伤瘢痕整复中具有较高的可行性。     

支架外固定联合局部转移皮瓣修复伴皮肤软组织缺损胫腓骨开放骨折

目的：分析支架外固定联合局部转移皮瓣在修复伴皮肤缺损胫腓骨开放骨折中的应用。方法：选择胫骨或胫腓骨开放骨折伴皮肤缺损患者61例,分为观察组42例,对照组19例。观察组急诊清创、支架外固定骨折,一期或二期局部转移皮瓣修复皮肤缺损。对照组急诊清创、骨折内固定后直接缝合撕裂的皮肤。结果：观察组39例骨折达到临床愈合标准,2例瘢痕愈合,1例出现感染。对照组11例骨折达到临床愈合标准,8例发生皮肤及软组织缺血、坏死。结论：支架外固定联合局部转移皮瓣手术修复胫腓骨开放骨折伴皮肤软组织缺损疗效确切,值得临床推广。     

外踝上穿支皮瓣修复伴肌腱和（或）骨外露的小腿及足部软组织缺损创面疗效分析

【摘要】 目的 探讨外踝上穿支皮瓣修复伴肌腱和 (或) 骨外露的小腿及足部软组织缺损创面的临床效果。方法 给予 2018 年 6 月至 2020 年 6 月芜湖市第二人民医院收治的 16 例伴肌腱和 (或) 骨外露的小腿及足部软组织缺损患者应用外踝上穿支皮瓣进行修复, 观察皮瓣成活情况? 皮瓣转移区愈后皮肤外观及感觉功能恢复情况。结果 16 例患者中除 4 例患者因皮瓣远端少量表浅组织坏死行二次植皮后愈合外, 其余 12 例患者术后皮瓣均成活良好, 创面一期愈合, 愈合时间为7～30 d。术后随访6个月～2 年, 所有患者愈后皮肤均恢复良好, 无复发, 皮肤色泽与周围正常皮肤无明显差别, 质地柔软,肢体感觉功能分级均为 S2 级, 行走时无疼痛等不适症状。结论 采用外踝上穿支皮瓣修复伴肌腱和 (或) 骨外露的小腿及足部软组织缺损创面, 皮瓣成活率较高, 创面愈合较好, 值得临床推广应用。     

鼻唇沟瓣修复颌面部恶性肿瘤术后缺损的临床观察

目的探讨应用鼻唇沟皮瓣修复颌面部恶性肿瘤术后软组织缺损的临床经验。方法选取2008年1月-2013年1月颌面部恶性肿瘤术后缺损患者38例,随机分为治疗组和对照组,各19例。皮瓣的选择分别为鼻唇沟皮瓣和前臂皮瓣。比较两组患者术后皮瓣成活率率与并发症发生率等指标。结果术后治疗组皮瓣成活率100%、受区Ⅰ期修复率100%显著高于对照组94.74%、94.74%;术后6个月,治疗组并发症率15.79%显著低于对照组42.11%,结果具有统计学意义（P〈0.05）。结论鼻唇沟皮瓣修复颌面部恶性肿瘤术后组织缺损成功率较高,颜面及口腔外形及功能恢复良好,建议中等大小的面部组织缺损临床推广使用。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.     

Prevalence and severity of hip and groin pain in sub‐elite male football: a cross‐sectional cohort study of 695 players

The purpose of this study was twofold: (a) to investigate the prevalence of hip and groin pain in sub‐elite male adult football in Denmark and (b) to explore the association between prevalence and duration of hip and groin pain in the previous season with the Copenhagen Hip and Groin Outcome Score (HAGOS) in the beginning of the new season. In total 695 respondents from 40 teams (Division 1–4) were included. Players completed in the beginning of the new season (July–Sept 2011) a self‐reported paper questionnaire on hip and/or groin pain during the previous season and HAGOS. In total 49% (95% CI: 45–52%) reported hip and/or groin pain during the previous season. Of these, 31% (95% CI: 26–36%) reported pain for >6 weeks. Players with the longest duration of pain during the previous season had the lowest HAGOS scores, when assessed at the beginning of the new season, P < 0.001. This study documents that half of sub‐elite male adult football players report pain in the hip and/or groin during a football season. The football players with the longest duration of pain in previous season displayed the lowest HAGOS scores in the beginning of the new season.     

Bronchial stump fistula :treatment with covered retrievable hinged metallic stents-preliminary clinical experience

Objective To evaluate the preliminaily clinical efficacy and retrievability of a retrievable hinged covered metallic stent in the treatment of the bronchial stump fistula （BSF）. Methods Between April 2003 and March 2005, 8 patients with bronchial stump fistula after pneumonectomy or lobectomy were treated with two types （A and B） of retrievable hinged covered metallic stents. Type A stent was placed in 6 patients and type B in 2 under fluoroscopic guidance. The stent was removed with a retrieval set when BSF was healed or complications occurred. Results Stent placement in the bronchial tree was technically successful in all patients, without procedure-related complications. Immediate closure of the BSF was achieved in all patients after the procedure. Stents were removed from all patients but one. Removal of the stents was difficult in two patients due to tissue hyperplasia. Patients were followed up for 6 - 21 months. Placement of the stents remained stable in all patients except one due to severe cough. Permanent closure of BSF was achieved in 7 （87.5%） of 8 patients. Conclusion Use of a retrievable hinged covered expandable metallic stent is a simple, safe, and effective procedure for closure of the BSF. Retrieval of the stent seems to be feasible. （J Intervent Radiol, 2007, 16： 253-257）