首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 11 毫秒
1.
目的 研究孕期增重以及产后膳食对产后体重滞留的影响 方法 采用队列研究的方法,以在北京北方医院进行产后复查的产妇为研究对象,分别在产后1个月、6个月进行追踪随访,调查研究对象的一般信息、孕前、分娩前、产后1个月、6个月的体重;用半定量的食物频数法,收集研究对象的膳食摄入信息。利用多元线性回归模型,分析孕期增重以及膳食摄入量与产后体重滞留的关系。结果 孕期增重(β = 0.73, 95%CI: 0.52~0.71,β = 0.67, 95%CI: 0.51~0.77)、软饮料摄入量(β = 0.14, 95%CI: 0.14~1.34,β = 0.15, 95%CI: 0.05~1.53)与产后1、6个月体重滞留呈正相关关系,关联具有统计学意义;按照喂养方式分层后,孕期增重、软饮料摄入与产后1个月、6个月喂养方式之间不存在交互作用。结论 孕期增重与产后软饮料摄入与产后体重滞留有关,与软饮料摄入量相比,孕期增重是产后体重滞留更重要的预测因子。  相似文献   

2.
ObjectiveTo preliminarily examine throughout pregnancy and 12 months postpartum: 1) the critical timings of abnormal gestational weight gain (GWG) among quitters and non-quitters; 2) the consequences of abnormal GWG on weight retention during postpartum; 3) the potential difference in GWG by timing of quitting (early vs. late).MethodsWe included 59 pregnant smokers (49 quitters and 10 non-quitters) from two clinical pilot studies. Smoking status and weight were repeatedly measured throughout pregnancy and postpartum. Weight trajectories were analyzed using mixed models with smoking cessation status, pregnancy week or postpartum month, their interaction term, and potential confounders.ResultsAt enrollment, mothers had a mean BMI of 28.7 (SD, 7.2) and mean age of 30.1 years (SD, 5.8). Both groups had a linear increase in GWG, but quitters had a much higher rate of GWG (0.87 vs. 0.22 pounds/week) than non-quitters throughout pregnancy. Before delivery, 63.3% of quitters and 20.0% of non-quitters had excessive total GWG, while 12.2% of quitters and 60.0% of non-quitters had inadequate total GWG (p-value=0.004). Early quitters (<21 weeks) had a higher risk of excessive GWG (85.0%) than late quitters (≥21 weeks, 36.4%) (p-value=0.026). After delivery, quitters’ weight remained stable following a rapid weight loss, whereas non-quitters’ weight increased continuously.ConclusionsNon-quitters have a high risk of inadequate GWG, while quitters, especially early quitters, have a high risk of excessive GWG. The group difference in weight trajectories lasted from conception to postpartum.  相似文献   

3.
目的  探讨产前抑郁与产后抑郁症的关系。 方法  选择银川市妇幼保健院与中卫市中医院2所医院的200名住院待产妇, 采用抑郁自评量表(self rating depression scale, SDS)与爱丁堡产后抑郁量表(Edinburgh postnatal depression scale, EPDS)分别调查产前与产后抑郁状况。 结果  200名产妇产前抑郁检出率为20.0%, 产后3 d抑郁检出率为26.0%, 产后42 d检出率为15.5%。有产前抑郁的产妇产后3 d(χ2=9.381, P=0.002)、产后42 d(χ2=11.923, P=0.001)抑郁检出率高于无产前抑郁者。Pearson相关分析显示, 产前SDS得分与产后3 d的EPDS得分、与产后42 d的EPDS得分均呈正相关(均有P < 0.05)。广义估计方程分析亦得出产前抑郁与产后3 d抑郁、产后42 d抑郁均呈正相关(均有P < 0.05)。多因素Logistic回归分析模型显示产前抑郁是产后3 d抑郁(OR=2.678, 95%CI:1.241~5.781, P=0.012)、产后42 d抑郁(OR=3.180, 95%CI:1.303~7.763, P=0.011)的危险因素。 结论  产前抑郁与产后抑郁症呈正相关, 产前抑郁增加了产后抑郁症的危险性。  相似文献   

4.
Ertel KA, Koenen KC, Rich‐Edwards JW, Gillman MW. Antenatal and postpartum depressive symptoms are differentially associated with early childhood weight and adiposity. Paediatric and Perinatal Epidemiology 2010; 24: 179–189. Antenatal depression is associated with small‐for‐gestational age, but few studies have examined associations with weight during childhood. Similarly, few studies address whether antenatal and postpartum depression differentially affect child weight. Among 838 mother–child dyads in Project Viva, a prospective cohort study, we examined relationships of antenatal and postpartum depression with child weight and adiposity. We assessed maternal depression at mid‐pregnancy and 6 months postpartum with the Edinburgh Postnatal Depression Scale (score ≥13 indicating probable depression). We assessed child outcomes at age 3 years: body mass index (BMI) z‐score, weight‐for‐height z‐score, sum of subscapular (SS) and triceps (TR) skinfold thickness (SS + TR) for overall adiposity, and SS : TR ratio for central adiposity. Sixty‐nine (8.2%) women experienced antenatal depression and 59 (7.0%) postpartum depression. Mean (SD) outcomes at age 3 were: BMI z‐score, 0.45 (1.01); SS + TR, 16.72 (4.03) mm; SS : TR, 0.64 (0.15). In multivariable models, antenatal depression was associated with lower child BMI z‐score (?0.24 [95% confidence interval: ?0.49, 0.00]), but higher SS : TR (0.05 [0.01, 0.09]). There was no evidence of a dose–response relationship between antenatal depression and these outcomes. Postpartum depression was associated with higher SS + TR (1.14 [0.11, 2.18]). In conclusion, whereas antenatal depression was associated with smaller size and central adiposity at age 3 years, postpartum depression was associated with higher overall adiposity.  相似文献   

5.
目的 通过监测妇女产后2年内体重滞留变化,探讨孕妇产后体力活动和睡眠时长等因素对产后体重滞留的影响,为慢性病预防控制提供依据。方法 将2012年7月至2013年1月在合肥市妇幼保健院参加产后42天体检的418名妇女纳入研究,建立基线资料。于产后42 d、3、6、9、12、18、24个月对其进行随访调查。采用重复测量资料的方差分析各影响因素与体重滞留的关系。结果 产后42 d、3 月、6 月、9 月、12 月、18 月和24月获得有效数据分别为418、314、299、278、264、229和193例。研究对象的孕前体重为(53.46±6.70) kg,产后42 d、6 月、12月、18 月和24 月体重滞留分别为(7.14±4.04) kg、(6.81±5.02) kg、(5.19±3.82) kg、(5.35±4.52) kg和(5.15±3.68) kg。重复测量资料方差分析结果显示,孕妇产后不同时间段体重滞留的差异有统计学意义(P <0.01),不同时间的体力活动差异有统计学意义(P <0.01),不同时间的睡眠时长差异有统计学意义(P <0.01)。结论 产后体力活动和睡眠时长是影响产后体重滞留的重要因素。  相似文献   

6.
目的 本研究旨在分析母亲孕前体质指数(body mass index,BMI)、孕期增重(gestational weight gain,GWG)对新生儿出生体重及分娩方式的影响。方法 2015年7月 - 2018年12月,在天津市纳入1 868对母婴,进行问卷调查。采用多重线性回归与logistic回归模型探索母亲孕前BMI和GWG对新生儿出生体重及分娩方式的影响。结果 新生儿出生体重随孕前BMI的增加而增加(β = 0.010, 95%CI: 0.005-0.016, P<0.001);与GWG不足组对比,GWG过多组新生儿出生体重较高(β = 0.100, 95%CI: 0.053-0.148, P<0.001)。巨大儿的出生率随孕前BMI的增加而增加(OR = 1.086, 95%CI: 1.028-1.147, P = 0.003)。剖宫产的发生率随着孕前BMI的增加而增加(OR = 1.054, 95%CI: 1.021-1.087, P = 0.001)。结论 合理控制孕前BMI,避免孕期体重过度增长,有利于新生儿体重的控制,降低巨大儿和剖宫产的发生率。  相似文献   

7.
目的:了解孕前体重指数(BMI)与孕期增重、产后42天体重恢复情况及影响产后体重恢复的因素。方法:采用方便取样,对产后42天复查的产妇进行回顾性调查。结果:①不同孕前BMI妇女孕期平均增重均大于12.50kg;②不同孕前BMI者产后42天体重均存在滞留现象,平均滞留7.50kg(中位数);③影响产后体重恢复的相关因素有孕前BMI、孕期增重、喂养方式等。结论:产后体重恢复受多种因素影响,针对这些相关因素指导妇女顺利渡过孕产期,促进产后恢复。  相似文献   

8.
《Annals of epidemiology》2014,24(11):793-800.e1
PurposeTo examine the relations of maternal prepregnancy body mass index (ppBMI) and gestational weight gain (GWG) with offspring cardiometabolic health.DesignWe studied 1090 mother–child pairs in Project Viva, a Boston-area prebirth cohort. We measured overall (dual x-ray absorptiometry total fat; body mass index z-score) and central adiposity (dual x-ray absorptiometry trunk fat), and systolic blood pressure in offspring at 6 to 10 years. Fasting bloods (n = 687) were assayed for insulin and glucose (for calculation of homeostatic model assessment of insulin resistance), triglycerides, leptin, adiponectin, high sensitivity C-reactive protein, and interleukin 6. Using multivariable linear regression, we examined differences in offspring outcomes per 1 SD maternal ppBMI and GWG.ResultsAfter adjustment for confounders, each 5 kg/m2 higher ppBMI corresponded with 0.92 kg (95% confidence interval, 0.70–1.14) higher total fat, 0.27 BMI z-score (0.21–0.32), and 0.39 kg (0.29–0.49) trunk fat. ppBMI was also positively associated with homeostatic model assessment of insulin resistance, leptin, high sensitivity C-reactive protein, interleukin 6, and systolic blood pressure; and lower adiponectin. Each 5 kg of GWG predicted greater adiposity (0.33 kg [0.11–0.54] total fat; 0.14 kg [0.04–0.23] trunk fat) and higher leptin (6% [0%–13%]) in offspring after accounting for confounders and ppBMI.ConclusionsChildren born to heavier mothers have more overall and central fat and greater cardiometabolic risk. Offspring of women with higher GWG had greater adiposity and higher leptin.  相似文献   

9.
目的:探讨孕妇孕前体质指数(BMI)及孕期增重对新生儿出生体重和分娩方式的影响。方法:选取474名身体健康的孕晚期妇女作为调查对象,于分娩前后对孕妇及新生儿进行追踪调查,获得有效问卷442份。按孕前BMI及孕期增重分组进行整理分析。结果:调查对象孕期平均增重(15.80±4.60)kg,孕前超重及肥胖者孕期增重低于孕前低体重者(F=3.87,P<0.01)。新生儿平均出生体重(3 240.30±377.60)g,其中低出生体重儿10例(2.26%),巨大儿16例(3.62%)。剖宫产者占48.20%。Logistic回归分析显示,妇女孕前超重及肥胖是分娩巨大儿及剖宫产的危险因素;孕期增重>21.00 kg是分娩巨大儿的危险因素;增重>18.00 kg是剖宫产发生的危险因素。结论:孕前体质指数和孕期增重是巨大儿和剖宫产的重要影响因素,保持适宜的孕前体重及孕期合理增重对于改善出生结局有着积极的意义。  相似文献   

10.
目的 研究孕前体质指数(pBMI)及妊娠期体重增长(GWG)与产妇患妊娠期糖尿病及高血压的关系.方法 回顾性分析2011年2月至2012年2月行常规产前检查并住院分娩的产妇1240例,记录pBMI、GWG、第24~ 28孕周的空腹血糖及血压水平.采用相关性分析及Logistic回归分析的方法研究pBMI及GWG与妊娠期糖尿病及高血压的关系.结果 根据pBMI分组,轻体重组260例,正常体重组917例,超重组36例,肥胖组27例.根据GWG分组,低度增长组104例,正常增长组758例,中度增长组249例,高度增长组129例.pBMI与GWG呈负相关(r=-0.646,P<0.01).以正常体重组为参照,超重组妊娠期糖尿病发病率为11.11%(4/36),OR值为4.120,P<0.05;肥胖组妊娠期糖尿病发病率为18.52%(5/27),OR值为7.492,P<0.05;肥胖组妊娠期高血压发病率为11.11%(3/27),OR值为6.243,P<0.05.以正常增长组为参照,低度增长组妊娠期糖尿病发病率为15.38%(16/104),OR值为9.006,P<0.05;低度增长组妊娠期高血压发病率为4.81%(5/104),OR值为3.140,P<0.05;高度增长组妊娠期高血压发病率为4.65%(6/129),OR值为3.033,P<0.05.各组空腹血糖及血压水平比较差异无统计学意义(P>0.05).结论 pBMI与GWG呈负相关,pBMI偏高及GWG偏低均是患妊娠期糖尿病及高血压的危险因素.  相似文献   

11.
目的探讨产前抑郁与胎儿出生体质量和分娩孕周的相关性。方法选取2011年8月-2018年5月在舟山市妇幼保健院产检的1 616例孕妇为研究对象,采用自编问卷采集研究对象一般社会人口学信息、器质性疾病、精神疾病、创伤史及分娩史,采用抑郁自评量表(SDS)评价抑郁状态,采用焦虑自评量表(SAS)评价焦虑状态,并从舟山市妇幼保健院电子医疗系统中提取分娩的相关信息,采用多元线性回归分析产前抑郁与胎儿出生体质量和分娩孕周的相关性。结果孕期无抑郁组脑力劳动者、高孕次人数、出现早孕反应及孕期存在焦虑的比例均少于孕期有抑郁组,差异均有统计学意义(均P<0. 001);无抑郁组平均文化水平高于有抑郁组,差异有统计学意义(P<0. 001)。多元线性回归分析结果显示,产前抑郁与孕妇分娩孕周无关;孕早期中重度抑郁能降低胎儿出生体质量(β=-69. 76,P=0. 039 1),各怀孕阶段中至少1期(β=-59. 05,P=0. 005 1)、至少2期(β=-61. 49,P=0. 027 1)出现抑郁均能降低胎儿出生体质量,至少1期出现中重度抑郁(β=-88. 03,P=0. 004 5)对降低胎儿出生体质量的效应更为显著。结论产前抑郁与胎儿出生体质量呈负相关关系,但与出生孕周无关,因此要加强孕妇的心理健康管理,维护母婴健康。  相似文献   

12.
目的 分析孕妇产后久坐行为对产后体重滞留的情况及其影响因素。方法 2012年5月至2013年8月在合肥市妇幼保健所收集1 220名产后42 d产妇建立基线资料,从该市孕产妇信息管理系统获取孕前体重及分娩信息,分别于产后3、6、9、12个月随访,观察产妇久坐时间等指标,采用重复测量资料的方差分析和混合效应模型分析产妇久坐与体重滞留的关系。结果1 220名产妇最终追踪到有效数据者1 141名。该研究人群孕前体重为(53.22±6.88)kg,产后42 d和3、6、9、12个月的体重(kg)滞留分别为7.85±5.11、7.51±5.40、5.79±5.18、4.42±4.91、3.26±4.65。重复测量资料方差分析结果显示,孕妇产后不同时间段体重滞留的差异有统计学意义(P<0.001);混合效应模型显示,分步调整孕前BMI、哺乳方式、分娩方式等混杂因素后,产妇久坐行为与产后体重滞留间的差异有统计学意义(P<0.001),逐步调整混杂因素后显示混合效应模型结果稳定。结论 产妇久坐是影响产后体重滞留重要因素之一。  相似文献   

13.
目的 探讨妊娠期间增重状况及妊娠晚期体质量指数对产后泌乳的影响.方法 选取2012年7月至2015年9月在温州市中心医院妇产科分娩的产妇623例,依据泌乳水平分为A组(泌乳量>45mL,泌乳始动时间≤48h)和B组(泌乳量≤45mL,泌乳始动时间>48h),比较两组产妇分娩后24h泌乳素、泌乳量及泌乳始动率,对两组产妇的临床资料进行单因素和多因素Logistic回归分析.结果 A组产妇的泌乳素、泌乳量均显著高于B组(t值分别为2.357、2.093,均P<0.05),且泌乳始动率显著高于B组(χ2=6.108,P<0.05).两组产妇的年龄、分娩孕周、分娩方式、妊娠晚期体质量指数、妊娠期增重、妊娠期高血压疾病、妊娠期糖尿病比较均有显著性差异(χ2=3.893~8.324,均P<0.05),而产次、新生儿体重比较无显著性差异(χ2值分别为0.687、2.451,均P>0.05).对单因素分析中有统计学意义的因素进行多因素Logistic回归分析,结果显示产妇年龄大、妊娠晚期体质量指数高、妊娠期增重过多是影响产妇泌乳水平的独立危险因素(OR值分别为2.942、2.012、3.522,均P<0.05).结论 妊娠晚期体质量指数过高、增重过多是影响产妇泌乳水平的独立危险因素,产妇应在妊娠期加强锻炼,避免肥胖.  相似文献   

14.
BackgroundWomen of childbearing age are predisposed to becoming overweight or obese. This study determines the mean, prevalence and factors associated with 6 months postpartum weight retention among urban Malaysian mothers.MethodsA prospective cohort study was conducted at baseline (after delivery), 2, 4 and 6 months postpartum. From 638 eligible mothers initially recruited, 420 completed until 6 months. Dependent variable was weight retention, defined as difference between weight at 6 months postpartum and pre-pregnancy weight, and weight retention ≥5 kg was considered excessive. Independent variables included socio-demographic, history of pregnancy and delivery, lifestyle, practices and traditional postpartum practices.ResultsAverage age was 29.61 ± 4.71 years, majority (83.3%) were Malays, 58.8% (low education), 70.0% (employed), 65.2% (middle income family), 33.8% (primiparous) and 66.7% (normal/instrumental delivery). Average gestational weight gain was 12.90 ± 5.18 kg. Mean postpartum weight retention was 3.12 ± 4.76 kg, 33.8% retaining ≥5 kg. Bivariable analysis showed low income, primiparity, gestational weight gain ≥12 kg, less active physically, higher energy, protein, carbohydrate and fat intake in diet, never using hot stone compression and not continuing breastfeeding were significantly associated with higher 6 months postpartum weight retention. From multivariable linear regression analysis, less active physically, higher energy intake in diet, gestational weight gain ≥12 kg, not continuing breastfeeding 6 months postpartum and never using hot stone compression could explain 55.1% variation in 6 months postpartum weight retention.ConclusionWomen need to control gestational weight gain, remain physically active, reduce energy intake, breastfeed for at least 6 months and use hot stone compression to prevent high postpartum weight retention.  相似文献   

15.
目的 探讨孕期增重及其总增重与妊娠期糖尿病(GDM)的关系。方法 采用前瞻性队列研究,于2013年3-9月选取成都市妇幼医疗机构产前门诊829名单胎健康孕妇作为基线调查对象,通过问卷调查于首次纳入时收集孕妇孕前等基线资料,于孕第(12±1)、(28±1)、(36±1)周及分娩前分别收集孕妇锻炼习惯、膳食摄入情况等信息和测量孕妇体重,分娩后收集分娩孕周等分娩信息。GDM诊断按中国妊娠合并糖尿病防治指南(2014),采用多因素logistic回归分析孕早、中、晚期增重和孕期总增重与GDM的关系。结果 共682名孕妇纳入数据分析。控制生育年龄、孕前BMI、糖尿病家族史、高血压家族史、孕早期锻炼、产次、文化程度、家庭人均月收入及膳食能量等混杂因素后,多因素logistic回归分析显示:与孕早期增重适宜组相比,孕早期增重不足组和增重过多组GDM发生风险均增加(分别为OR=1.23,95% CI:0.63~2.38和OR=2.20,95% CI:1.12~4.35);与孕中期增重适宜组相比,孕中期增重不足组和过多组GDM发生风险均降低(OR=0.47,95% CI:0.18~1.19和OR=0.78,95% CI:0.43~1.42);与孕晚期增重适宜组相比,孕晚期增重不足组GDM发生风险增加(OR=1.48,95% CI:0.77~2.84),增重过多组GDM发生风险降低(OR=0.53,95% CI:0.28~0.99);与孕期总增重适宜组相比,总增重不足组GDM发生风险增加(OR=2.16,95% CI:1.04~4.46),总增重过多组GDM发生风险降低(OR=0.74,95% CI:0.38~1.46)。结论 孕早期增重不足和过多均可能增加GDM发生风险,孕早期可能是影响GDM发生的关键时期,孕中晚期增重对GDM的影响还有待进一步论证。  相似文献   

16.
目的:探讨我国北方地区足月妊娠妇女孕期体重增长的适宜范围。方法:收集我国北方地区5 072例单胎足月初产妇孕前、孕期及产后42天资料,按照中国成人体重指数(BM I)分类要求将5 072例孕妇分组,了解各组的孕期体重增长情况,分析各组不同孕期体重增长对母儿不良妊娠结局发生率的影响,从而为各组推荐孕期体重增长的适宜范围。结果:5 072例孕妇中,孕前BM I<18.5 kg/m2,18.5~23.9 kg/m2及≥24 kg/m2的孕妇分别占16.8%,66.8%及16.4%,不良妊娠结局发生率最低的孕期体重增长范围分别为12~18 kg,10.0~16.0 kg及8.0~14.0 kg,(P<0.05),推荐的孕期体重增长范围分别为12~18 kg,10.0~16.0 kg及8.0~14.0 kg。结论:我国北方地区孕前低、正常、超重及肥胖组孕妇的平均孕期体重增长均较高,建议其孕期体重增长范围分别控制在12~18 kg,10.0~16.0 kg及8.0~14.0 kg。  相似文献   

17.
目的 系统评价妊娠期糖尿病与产后抑郁的关系。方法 检索Embase、Cochrane Library、PubMed、Web of Science、PsycINFO、中国知网、万方及维普数据库中探讨糖尿病与产后抑郁关系的研究,时限均从建库至2020年7月1日。同时对最终纳入的文献进行数据提取与质量评价,并采用Stata 14.0软件进行Meta分析。结果 最终纳入13项队列研究,共计736598名患者。文献质量评价均处于中高水平。Meta分析结果显示:妊娠期糖尿病与产后抑郁呈显著相关性(OR=2.02,95%CI: 1.44~2.81,P<0.001)。亚组分析显示:不同研究地区或国家[伊朗(OR=2.04)、美国(OR=1.47)、欧洲(OR=2.60)]、糖尿病诊断依据[临床诊断(OR=2.02)、自我报告(OR=1.87)]、产后抑郁评估期[产后6周及以下(OR=2.00)、产后6周以上(OR=2.14)]、抑郁测量工具[EPDS (OR=2.05)、ICD (OR=1.57)]中妊娠期糖尿病均与产后抑郁呈显著相关性。结论 产妇妊娠期糖尿病与产后抑郁具有显著相关性,糖尿病是产后抑郁的危险因素。  相似文献   

18.
目的 探讨巨大儿发生与孕前超重、孕期过度增重的直接关联及关联强度。方法 2015年1月起在上海市浦东新区妇幼保健院建立孕妇队列,创建孕妇健康档案,收集孕期及分娩信息,包括一般人口学特征、孕前体重、孕期增重、分娩体重、孕期健康状况及各种孕期并发症、分娩情况等,计算孕前BMI及孕期增重,收集新生儿出生体重,了解巨大儿发生与孕前超重、孕期过度增重之间的关系。结果 巨大儿发生率为6.6%(149/2 243)。不同孕前BMI组巨大儿发生率差异有统计学意义(P=0.001)。在控制了孕妇年龄、孕产史等因素后,logistic回归分析结果显示,与孕前BMI适宜的孕妇比,孕前BMI超重以及肥胖的孕妇生产巨大儿的风险均增加(OR=3.12,95%CI:1.35~7.22,P=0.008; OR=2.99,95%CI:1.17~7.63,P=0.022)。不同孕期增重组巨大儿发生率差异有统计学意义(P=0.002)。在控制了孕妇年龄、孕产史、孕期并发症等因素后,logistic回归分析结果显示,与孕期增重适宜的孕妇比,孕期增重不足的孕妇生产巨大儿的风险降低(OR=0.52,95%CI:0.30~0.90,P=0.019)。而孕期过度增重在调整了各种孕期指标后,与孕期增重适宜的孕妇比,巨大儿发生风险差异有统计学意义(OR=1.41,95%CI:0.96~2.09,P=0.084)。结论 孕前超重或肥胖是巨大儿发生的风险因素。  相似文献   

19.
目的 探讨孕前BMI和孕期增重与子痫前期(PE)及其临床亚型的发生风险的关系。方法 选取2012年3月至2016年9月在山西医科大学第一医院妇产科分娩的孕妇,根据纳入排除标准,共纳入9 274例孕妇,901例PE孕妇作为病例组,8 373例非PE孕妇作为对照组。收集一般人口学特征、孕前身高和体重、孕期生活方式、生育史和疾病史等资料,计算孕前BMI及孕期增重。采用非条件logistic回归分析孕前BMI和孕期增重与PE及其临床亚型的关系。结果 PE中早发型PE (EOPE)401例、晚发型PE (LOPE)500例,轻度PE (MPE)178例、重度PE (SPE)723例。PE孕妇和非PE孕妇在年龄、居住地、产次、妊娠期糖尿病及高血压家族史等方面差异有统计学意义(P<0.05)。调整以上因素后,logistic回归分析结果显示,孕前BMI<18.5 kg/m2和孕期增重不足是PE的保护因素(OR=0.74,95%CI:0.56~0.98;OR=0.78,95%CI:0.62~0.99),孕前BMI ≥ 24.0 kg/m2和孕期增重过多是PE的危险因素(OR=1.82,95%CI:1.54~2.14;OR=1.82,95%CI:1.54~2.15)。对PE临床亚型分析后结果显示,孕前BMI<18.5 kg/m2是EOPE和MPE的保护因素(OR=0.52,95%CI:0.32~0.83;OR=0.47,95%CI:0.23~0.97),孕前BMI ≥ 24.0 kg/m2和孕期增重过多是PE临床亚型的危险因素。按孕前BMI分层后,孕前18.5 kg/m2 ≤ BMI<24.0 kg/m2和孕前BMI ≥ 24.0 kg/m2的孕妇中孕期增重过多(OR=1.86,95%CI:1.51~2.30;OR=1.90,95%CI:1.39~2.60)均是PE的危险因素;孕前BMI ≥ 24.0 kg/m2的孕妇中孕期增重不足(OR=0.55,95%CI:0.34~0.89)是PE的保护因素。孕前BMI<18.5 kg/m2的孕妇中孕期增重过多(OR=4.05,95%CI:1.20~13.69)是EOPE的危险因素;孕前18.5 kg/m2 ≤ BMI<24.0 kg/m2的孕妇中孕期增重过多是PE各临床亚型的危险因素;孕前BMI ≥ 24.0 kg/m2的孕妇中孕期增重不足是EOPE和MPE的保护因素(OR=0.39,95%CI:0.19~0.80;OR=0.29,95%CI:0.11~0.77),孕期增重过多是EOPE、LOPE和SPE的危险因素(OR=1.60,95%CI:1.06~2.42;OR=2.20,95%CI:1.44~3.37;OR=2.28,95%CI:1.58~3.29)。结论 孕前BMI和孕期增重影响PE及其临床亚型的发生风险,且不同孕前BMI人群孕期增重对PE的影响有差异,提倡同时关注孕前BMI和孕期体重变化,从而减少PE发生。  相似文献   

20.

Background

This study was conducted to determine the relationship between unintended pregnancy and maternal behaviors before, during and after pregnancy.

Study Design

Data were analyzed from a stratified random sample of 9048 mothers who delivered live born infants between 2001 and 2006 and completed the Pregnancy Risk Assessment Monitoring System (PRAMS) survey 2 to 9 months after delivery. Binary and ordinal logistic regression methods with appropriate survey weights were used to control for socio-demographic factors.

Results

Compared to women with intended pregnancies, mothers with unwanted pregnancies were more likely to consume less than the recommended amount of preconception folic acid [adjusted odds ratio (OR) 2.39, 95% confidence interval (CI) 1.7-3.2], smoke prenatally (OR 2.03, 95% CI 1.5-2.9), smoke postpartum (OR 1.86, 95% CI 1.35-2.55) and report postpartum depression (OR 1.98, 95% CI 1.48-2.64); they were less likely to initiate prenatal care during the first trimester (OR 0.34, 95% CI 0.3-0.5) and breastfeed for 8 or more weeks (OR 0.74, 95% CI 0.57-0.97). Compared to women with intended pregnancies, women with mistimed pregnancies were also more likely to consume inadequate folic acid, delay prenatal care and report postpartum depression.

Conclusion

Even after controlling for multiple socio-demographic factors, unwanted and mistimed pregnancies were associated with unhealthy perinatal behaviors.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号