显微手术治疗颅内血栓性巨大动脉瘤11例报告

目的 探讨颅内血栓性巨大动脉瘤的临床特点、手术方法和效果.方法 回顾性分析11例颅内血栓性巨大动脉瘤患者的临床表现、临床分型、手术方法及治疗效果.结果 手术方式包括动脉瘤夹闭、载瘤动脉塑形加血栓切除9例,动脉瘤孤立加血栓切除1例,颈内动脉颅外段结扎1例.10例术后复查DSA或CTA提示动脉瘤均消失.随访3-6个月,GOS评分恢复优良8例,轻残1例,重残1例,死亡1例.结论 颅内巨大血栓性动脉瘤手术治疗困难,载瘤动脉临时阻断、动脉瘤切开血栓清除、载瘤动脉塑形及术中微血管多普勒监测(MVD)是治疗血栓性巨大动脉瘤的主要方法.

Abstract：

Objective To study the clinical features and surgical management of intracranial thrombotic giant aneurysms.Methods A retrospective study was performed for 11 patients with intracranial thrombotic giant aneurysms.The clinical presentation, clinical classification, surgical approaches and therapeutic efficacy were reviewed.Results The treatment included thrombectomy - aneurysm clip reconstruction in 9 cases, thrombectomy - aneurysm isolate in 1, and cervical internal carotid artery ligation in 1.The postoperative DSA or CTA showed that complete angiographic obliteration was achieved in 10 cases.Follow - up period was from 3 months to 6 months, the clinical outcomes of these patients were evaluated by Glasgow Outcome Scale grades.GOS of 8 cases were improved.There were minor deficit in 1 case, major deficit in 1 and one death.Conclusions The surgical treatment for intracranial thrombotic giant aneurysms is very difficult.It is a good method to occlude the parent artery temporally, eliminate intraaneurysmal thrombus and reconstruct parent artery.Intraoperative microvascular Doppler sonography (MVD) monitoring is helpful.     

Wall shear stress in intracranial aneurysms and adjacent arteries

Hemodynamic parameters play an important role in aneurysm formation and growth. However, it is difficult to directly observe a rapidly growing de novo aneurysm in a patient. To investigate possible associations between hemodynamic parameters and the formation and growth of intracranial aneurysms, the present study constructed a computational model of a case with an internal carotid artery aneurysm and an anterior communicating artery aneurysm, based on the CT angiography findings of a patient. To simulate the formation of the anterior communicating artery aneurysm and the growth of the internal carotid artery aneurysm, we then constructed a model that virtually removed the anterior communicating artery aneurysm, and a further two models that also progressively decreased the size of the internal carotid artery aneurysm. Computational simulations of the fluid dynamics of the four models were performed under pulsatile flow conditions, and wall shear stress was compared among the different models. In the three aneurysm growth models, increasing size of the aneurysm was associated with an increased area of low wall shear stress, a significant decrease in wall shear stress at the dome of the aneurysm, and a significant change in the wall shear stress of the parent artery. The wall shear stress of the anterior communicating artery remained low, and was significantly lower than the wall shear stress at the bifurcation of the internal carotid artery or the bifurcation of the middle cerebral artery. After formation of the anterior communicating artery aneurysm, the wall shear stress at the dome of the internal carotid artery aneurysm increased significantly, and the wall shear stress in the upstream arteries also changed significantly. These findings indicate that low wall shear stress may be associated with the initiation and growth of aneurysms, and that aneurysm formation and growth may influence hemodynamic parameters in the local and adjacent arteries.     

颈内动脉床突上段血泡样动脉瘤手术治疗

目的 探讨颈内动脉床突上段血泡样动脉瘤(BBA)的手术技巧.方法 对7例开颅手术夹闭的BBA进行分析,采取额极软脑膜下分离,预先或术中临时阻断载瘤动脉,直接游离瘤颈两侧或载瘤动脉相连续部,分离出能够通过动脉瘤夹闭小空间即可,不必完全显露瘤体;强调选用小弯形动脉瘤夹一次夹闭,如果瘤颈撕裂在载瘤动脉临时孤立无充盈状态下,将瘤颈根部包括载瘤动脉壁连续部部分动脉壁一并夹闭.结果 本组6例术后完全康复;1例术后2周出现大脑半球大面积梗死,肢体偏瘫,痴呆.结论 采用特殊的手术技巧,能够减少BBA的手术风险,提高治愈率.

Abstract：

Objective To explore the surgical techniques for rare blood blister - like aneurysm (BBA) in the superior segment of clinoid process of internal carotid artery. Method The clinical data of seven cases of BBAs were studied. The separation of pia mater of the frontal pole was performed. The parent artery was blocked temporarily during the surgery. Sculpture type was adopted to directly dissociate the continuation part between the aneurysm neck and parent artery to get a small space enough for incarceration of aneurysm without exposure of the entire aneurysm. One incarceration of the lesser curvature - like aneurysm clip was specially performed to temporarily isolate the parent artery in the case of avulsion of aneurysm neck,to incarcerate the aneurysm root including the continuous part of parent artery wall in a nonfilling state. Results There were 6 cases of complete recovery after operation, 1 case of large area infarction of hemicerebrum after 2 weeks of operation resulting in hemiplegia and dementia Conclusions Special surgical techniques could reduce the surgical risk for BBA and improve curative rate.     

颈内动脉分叉部动脉瘤的手术及血管内治疗 （英文）

BACKGROUND Aneurysms of the internal carotid artery(ICA)bifurcation are rare,and no studies have compared patient outcomes after endovascular vs surgical treatment.OBJECTIVE To report the safety,efficacy,and follow-up outcome of these 2treatment options for patients with ICA bifurcation aneurysms.METHODS Patient and aneurysm characteristics,treatment results,and follow-up outcomes(at 30 months)were analyzed from patient records and review of imaging findings.RESULTS A total of 58 patients with ICA bifurcation aneurysms were treated.By interdisciplinary consensus,30 aneurysms were assigned for coiling and 28 for clipping.Patients who underwent surgical clipping were younger and had larger aneurysms.More patients were assigned to coiling if their aneurysms originated only from the ICA bifurcation or projected superiorly.For the combined angiographic endpoint,complete and nearly complete occlusion(Raymond-Roy I+II),similar rates of 96%(coiling)or 100%(clipping)could be achieved.Raymond-Roy I occlusion occurred more often after clipping(79%vs 41%coiling).Follow-up of the endovascular group showed minor recanalization of the aneurysm neck(Raymond-Roy II)in 42%.One patient(4%)showed a major recanalization(Raymond-Roy III)and needed retreatment.For incidental findings,no bleeding complications or new persistent neurological deficits occurred during follow-up.CONCLUSION Treatment of ICA bifurcation aneurysms after interdisciplinary assignment to clipping or coiling is effective and safe.Despite significantly more minor recanalizations after coiling,the re-treatment rate was very low,and no bleeding was observed during follow-up.Multivariate analysis revealed that origin only from the ICA bifurcation was an independent predictor of aneurysm recanalization after endovascular treatment.     

眼动脉段颈内动脉巨大动脉瘤的手术治疗(一种新的治疗方法)

目的探讨颅内外颈内动脉临时阻断，动脉瘤直接穿刺夹闭眼动脉段颈内动脉巨大动脉瘤的可行性。方法经头颅CT或MRI扫描与DSA检查确诊为眼动脉段颈内动脉巨大动脉瘤后，病灶侧做压颈测验，侧支循环代偿率达70％以上时确定手术日期。手术时先暴露颅外颈内动脉（extracranial internal carotid artery, EICA），置粗丝线做临时阻断时用，后行额颞开颅术，暴露视神经颅内远端颈内动脉（intracranial distal internal carotid artery, IDICA）、后交通动脉（post-communicating artery，PCA），最后分离和聚露动脉瘤及其周围结构。临时阻断EICA、IDICA和PCA，穿刺针直接穿刺动脉瘤减压，待动脉瘤塌陷后夹闭动脉瘤颈。动脉瘤夹闭前后用TCD分别监测IDICA、PCA以及动脉瘤体的血流，变化。结果术后病人神志清楚，未出现新的神经系统征象，经DSA检查，动脉瘤消失，颈内动脉循环良好。结论颅内外颈内动脉临时阻断，动脉瘤抽吸夹闭眼动脉段颈内动脉巨大动脉瘤是一种简单、安全、疗效确切的方法。术中应用TCD监测，对预测预后有益。     

神经内镜辅助眶上锁孔入路早期夹闭前交通动脉瘤

目的 探讨应用神经内镜辅助眶上锁孔入路早期手术夹闭前交通动脉瘤的疗效.方法中南大学湘雅医学院附属海口医院神经外科自2002年1月至2010年1月采用神经内镜辅助眶上锁孔入路在出血早期(72 h内)手术治疗前交通动脉瘤(Hunt-Hess分级1～3级)患者35例,回顾性分析患者的临床资料和疗效.结果 35例患者均顺利完成动脉瘤夹闭.2例患者术中动脉瘤破裂,经临时阻断载瘤动脉快速解剖瘤颈后夹闭;患者均无入路相关的严重并发症;术后复查DSA或CTA证实动脉瘤夹闭完全,载瘤动脉无狭窄,远端动脉通畅良好.术后3个月复诊时,30例(85.7%)患者恢复良好(GOS评分4～5分),所有患者切口美容效果良好.结论 出血早期(72 h内)经神经内镜辅助眶上锁孔入路手术处理Hunt-Hess分级Ⅰ～Ⅲ级前交通动脉瘤患者安全、有效.

Abstract：

Objective To evaluate the effectiveness of the endoscope-assisted supraorbital keyhole approach in the early surgical treatment of patients with ruptured anterior communicating artery aneurysms (AcoA). Methods Thirty-five patients with ruptured AcoA, admitted to our hospital from January 2002 to January 2010, adopted clipping via endoscope-assisted supraorbital keyhole approach within 72 h of onset. The neurostatus of these patients were ranged from grade 1 to 3 (Hunt-Hiss Scale scores). The surgical details were described, and the clinical results were assessed according to the scores of Glasgow Outcome Scale.Results Operations were successfully finished in all patients; the endoscope-assisted supraorbital keyhole approach offered sufficient exposure of neurovascular structures for clipping AcoA. Intraoperative accidental aneurysm rupture occurred in 2 patients, but these events were managed successfully by blocking-up the parent artery and performing quick aneurysm neck dissection; no serious complications caused by the surgical approach occurred; postoperative DSA or CTA indicated that the aneurysm was totally clipped and the parent artery appeared no stenosis, and distal artery was unobstructed. Three months after the operation, 30 patients (85.7%) achieved very good outcomes (GOS:4-5 scores). All the patients achieved good cosmetic results. Conclusion In selected AcoA patients with grade 1-3, the endoscope-assisted supraorbital keyhole approach is safe and effective for gaining access to and treating the aneurysms on early hemorrhage stage.     

颅内镜像动脉瘤17例临床分析

目的 探讨颅内镜像动脉瘤的临床特征和手术方法.方法 解放军第二五一医院神经外科自2006年1月至2010年6月行显微外科手术治疗颅内镜像动脉瘤患者17例,回顾性分析患者的临床资料和疗效.结果 本组动脉瘤直接夹闭35个,未作处理1个,患者行一期手术9例,夹闭动脉瘤20个.二期手术7例,第一次手术夹闭动脉瘤7个,第二次手术夹闭动脉瘤7个.1例患者行一侧动脉瘤夹闭后对侧动脉瘤未处理;11例患者术后行CTA复查,夹闭的23个动脉瘤中2例瘤颈残留,余动脉瘤均消失,载瘤动脉通畅.GOS评分显示恢复优良12例,轻残4例,重残1例.结论 显微外科手术治疗颅内镜像动脉瘤效果显著.正确判断责任动脉瘤并首先处理,根据动脉瘤的部位、Hunt-Hess临床分级及患者周身状况等选择一期、分期手术可达到良好效果.

Abstract：

Objective To study the clinical characteristics and microsurgical skills of intracranial mirror-image aneurysm. Methods The clinical data and post-operative outcomes of 17 patients with 36 intracranial mirror-image aneurysms who underwent microsurgical operation were analyzed retrospectively. Results Thirty-five aneurysms were clipped directly and 1 did not give any treatment. One-time surgery was performed in 9 patients and 20 aneurysms were clipped. Two-stage operation was performed in the other 7 patients: 7 aneurysms were clipped in the first surgery and 7 in the second one. One patient received aneurysm clipping only in one side of the brain. CTA was performed again on 11 patients, noting that residual aneurysm neck of the 2 aneurysms existed in 23 clipped aneurysms, that the other aneurysms disappeared, and that the parent arteries were clear. GOS indicated that good surgical outcomes were achieved in 12 patients, light disability in 4 and severe disability in 1.Conclusion The surgical outcomes of intracranial mirror-image aneurysm performed microsurgical operation are predominance. Criminal aneurysms should be determined correctly and clipped firstly; and according to the sites and grades of the aneurysms and the patient's condition, good outcomes can be achieved by choosing one-time operation or two-stage operation.     

微血管多普勒监测下手术治疗大脑后动脉动脉瘤

目的 总结2006年1月至2009年12月我科收治的10例大脑后动脉动脉瘤的临床特征、手术入路和手术技巧.方法 10例中P1段3例,P2段5例,P3段2例.P1段动脉瘤采用颞下+翼点联合入路,P2、P3段动脉瘤采用颞下入路.在微血管多普勒监测下7例行动脉瘤颈夹闭术,2例行血管塑形动脉瘤夹闭术,1例行动脉瘤孤立术.其中3例巨大动脉瘤行动脉瘤切除术.结果 10例患者中6例恢复良好,2例术后出现动眼神经麻痹,1例出现同向偏盲,1例出现轻偏瘫,经治疗后均恢复正常.术前1例存在动眼神经麻痹和1例存在同向偏盲者手术后3个月恢复.结论 显微外科手术是治疗大脑后动脉瘤的主要方法,经颞下入路暴露充分,是一种安全、简便的入路.微血管多普勒在动脉瘤夹闭术中是一种直接、有效和便捷的监测方法,对提高手术治疗效果具有重要价值.

Abstract：

Objective To summarize the clinical features of intracranial aneurysms of posterior cerebral artery (PCA), and the surgical approaches and operative skills to treat them. Method The aneurysms arose from the P1 segment in 3 patients, the P2 segment in 5 patients and the P3 segment in 2 patients. Aneurysms on P1 segment were surgically treated via subtemporal associated pterional approach. Aneurysms on P2 and P3 segment were surgically treated via subtemporal approach. 7 aneurysms were successfully treated by clipping the aneurysmal neck,2 aneurysms were shaped and 1 aneurysm was isolated. 3 giant aneurysms were resected. Microvascular Doppler was conducted to examine the blood flow of aneurysms and parent arteries. Results 6 of 10 patients had postoperative good recovery. Temporal oculomotor palsy occurred in 2 patients, syntropic hemiablepsia occurred in 1 patients,light hemiplegia in 1 patient. All these patients were recovery with treatment. 1 oculomotor palsy and 1 syntropic hemiablepsia preoperation recovered postoperation after three months. Conclusions The microsurgery is one of the major methods for treating aneurysm of PCA. The subtemporal approach in treating aneurysm of PCA is simple,safe and good exposure. Microvascular doppler is a feasible, safe, and very reliable technique in aneurysm surgery.     

颅内-外动脉搭桥术治疗颅内巨大宽颈动脉瘤

颅内巨大动脉瘤 (giant aneurysms)是指最大直径≥2.5 cm的动脉瘤[1].尽管近年来动脉瘤治疗技术不断发展,但对一些巨大不规则形动脉瘤的治疗仍十分困难.由于巨大宽颈动脉瘤累及的动脉较长不宜或不能开颅直接手术塑形夹闭或经血管内进行动脉瘤的囊内栓塞治疗,临床处理较为困难.我们采用联合颅内-外动脉搭桥(extracranial-intracranial bypass, EIAB)和颈内动脉(internal carotid artery, ICA) Selverstone夹慢性阻断术治疗5例巨大宽颈动脉瘤,经随访,疗效满意,现报道如下:     

Pediatric intracranial aneurysms——clinical characteristics and therapeutic strategies

Objective To assess the radiological characteristics and therapeutic strategies of intracranial aneurysms in children. Methods From our dedicated neurovascular databank of patients, we reviewed 23 consecutive children who had 24 intracranial aneurysms. There were 14 boys and 9 girls with a mean age of 9.09 years ( range 1 - 14 years ). Results Intracranial aneurysms in children ≤ 14 years constituted 1.3% of all intracranial aneurysms. Internal Carotid artery (ICA) and middle cerebral artery (MCA) were the most frequent sites for aneurysms. About 58.3% of the aneurysms were complex, including dissecting, pseudoaneurysm, giant and fusiform aneurysm. 1/3 of all aneurysms were located in posterior circulation. Only 1 case had multiple aneurysms in this case series. Almost half of all cases presented with subarachnoid hemorrhage and others presented with mass effect. 14 cases underwent endovascular treatment. 4 patients received microsurgical therapy. 5 cases did not receive microsurgical or endovascular therapy, 2 of them whose aneurysms spontaneously thrombosed during follow up. One boy with left vertebral artery giant aneurysm died after endovascular therapy owing to gradual thrombosis in basilar artery. Another child had poor outcome because of rerupture of aneurysm before operation. Whereas the majority had a favorable outcome. Conclusions Intracranial aneurysms in children had many clinical and radiological characteristics different from those in adults : ( 1 ) remarkable male predominance; ( 2 ) ICA and MCA were the most common sites for aneurysms; (3) high incidence of large, traumatic, infectious, dissecting and fusiform aneurysms. (4)For pediatric intracranial aneurysms, both microsurgical approaches and endovascular treatment were effective. Endovaacular therapy was the best choice for complex aneurysms.     

Microsurgical treatment of large and giant paraclinoid carotid aneurysms using a revised endovascular suction decompression technique with Invatec Mo.Ma device

Endovascular retrograde suction decompression (RSD) with balloon occlusion of the internal carotid artery is helpful to facilitate clipping large and giant paraclinoid carotid aneurysms. The authors reported a revised endovascular technique without internal carotid access using Mo.Ma device and analyzed its feasibility. In the series, 15 consecutive patients harboring 15 large and giant paraclinoid carotid aneurysms were clipped with assistance of this revised RSD technique. The technical feasibility of the procedure, procedure-related complications, angiographic results, and clinical outcome were evaluated. Technical success was achieved in 14 patients with aneurysm neck clipping and internal carotid artery (ICA) patent. No complication related to this endovascular technique occurred. At follow-up (mean time 15.3 months), the modified Rankin Scale score was excellent in 11 patients, good in two patients and poor in one patient. Their preliminary experience indicates that revised retrograde suction decompression technique with Mo.Ma device seems effective and safe in the surgical treatment of large and giant paraclinoid ICA aneurysms.     

血液回抽吸技术在巨大动脉瘤手术中的应用

目的 探讨床突旁大型或巨大动脉瘤手术中血液回抽吸技术的方法和效果.方法 12例颈内动脉床突旁段大型或巨大动脉瘤均采用翼点入路,颈内动脉临时阻断孤立动脉瘤后用18号套管针在颈部颈内动脉阻断的远端穿刺,将套管针尾部用负压吸引器连接到血液回收装置,在不切开动脉瘤的情况下使动脉瘤塌陷.术中应用脑电图和体感诱发电位监测.结果 8例血液逆向抽吸后动脉瘤明显塌陷,将动脉瘤壁与周围结构剥离后夹闭.4例逆向抽吸后动脉瘤塌陷不明显,其中3例切开动脉瘤去除瘤内血栓后夹闭动脉瘤,1例改做动脉瘤孤立并行大隐静脉移植颈外动脉-大脑中动脉搭桥.8例术后行DSA检查,动脉瘤均夹闭满意.按改良COS评分术后良好为10例,差为1例,死亡l例.结论 血液回抽吸方法能使大部分床突旁大型或巨大动脉瘤塌陷,从而获得安全和满意的夹闭.术中应用电生理监测有助于发现早期的脑缺血和判断动脉瘤夹闭后有无载瘤动脉狭窄或误夹.     

双腔球囊导管在颅内大型、巨大型动脉瘤夹闭术中的临床应用

目的讨论颅内大型、巨大型动脉瘤夹闭术中双腔球囊导管（CBP）应用的若干问题。方法应用CBP辅助夹闭颅内大型、巨大型动脉瘤5例,动脉瘤最大直径20mml例,其余25-35mm。术前CBP预置在动脉瘤近端,术中显露部分瘤体后充盈球囊阻断血供,经内套管逆向抽吸导管远端的血液,瘤内压下降后夹闭瘤颈。结果5例均成功夹闭瘤颈。1例大脑中动脉瘤术后对侧肢体轻偏瘫,对症治疗后基本恢复,其余术后均无神经功能障碍。1例术后一年复查DSA,动脉瘤未见显影。结论双腔球囊导管（CBP）应用于颅内大型、巨大型动脉瘤夹闭术中,既可有效阻断载瘤动脉血流,又可通过逆向抽吸降低瘤内压,有利于防止瘤体破裂、安全夹闭瘤颈。     

Internal Carotid Artery Reconstruction Using Multiple Fenestrated Clips for Complete Occlusion of Large Paraclinoid Aneurysms

Objective

Although surgical techniques for clipping paraclinoid aneurysms have evolved significantly in recent times, direct microsurgical clipping of large and giant paraclinoid aneurysms remains a formidable surgical challenge. We review here our surgical experiences in direct surgical clipping of large and giant paraclinoid aneurysms, especially in dealing with anterior clinoidectomy, distal dural ring resection, optic canal unroofing, clipping techniques, and surgical complications.

Methods

Between September 2001 and February 2012, we directly obliterated ten large and giant paraclinoid aneurysms. In all cases, tailored orbito-zygomatic craniotomies with extradural and/or intradural clinoidectomy were performed. The efficacy of surgical clipping was evaluated with postoperative digital subtraction angiography and computed tomographic angiography.

Results

Of the ten cases reported, five each were of ruptured and unruptured aneurysms. Five aneurysms occurred in the carotid cave, two in the superior hypophyseal artery, two in the intracavernous, and one in the posterior wall. The mean diameter of the aneurysms sac was 18.8 mm in the greatest dimension. All large and giant paraclinoid aneurysms were obliterated with direct neck clipping without bypass. With the exception of the one intracavenous aneurysm, all large and giant paraclinoid aneurysms were occluded completely.

Conclusion

The key features of successful surgical clipping of large and giant paraclinoid aneurysms include enhancing exposure of proximal neck of aneurysms, establishing proximal control, and completely obliterating aneurysms with minimal manipulation of the optic nerve. Our results suggest that internal carotid artery reconstruction using multiple fenestrated clips without bypass may potentially achieve complete occlusion of large paraclinoid aneurysms.     

颈内动脉大型和巨大型动脉瘤的手术策略

目的探讨颈内动脉巨大动脉瘤的特点和手术策略。方法回顾性分析48例颈内动脉大型和巨大型动脉瘤的手术经验。手术均采用翼点人路，床突旁动脉瘤病例预先暴露颈部颈内动脉以备临时阻断。从硬脑膜内磨除前床突、视神经管上壁以及外侧嵴，以显露动脉瘤的近侧角。术中采用逆向抽吸法使动脉瘤塌陷，如动脉瘤内含机化血栓，则在临时阻断后切开瘤体，用CUSA和取瘤镊去除瘤内血栓，再将动脉瘤夹闭并达到视神经减压的目的。术中监测脑电图和体感诱发电位，并采用术中超声多普勒检查动脉血流。结果46例动脉瘤直接夹闭，2例海绵窦段动脉瘤行动脉瘤孤立并分别做颞浅动脉-大脑中动脉和大隐静脉移植颈外动脉-大脑中动脉搭桥手术。43例术后行DSA检查，绝大多数动脉瘤夹闭满意。按GOS评分术后良好为41例（85．4％），差为5例，死亡2例。结论充分显露、合理应用临时阻断技术、有效的动脉瘤减压，以及术中应用电生理监测和超声多普勒检查等辅助措施，能够取得动脉瘤的满意夹闭。     

球囊辅助夹闭术治疗颅内大型和巨大型动脉瘤

目的 探讨球囊辅助夹闭术治疗颅内大型和巨大型动脉瘤（LGIAs）的疗效。方法 回顾性分析2017~2020年在复合手术室行球囊辅助夹闭术治疗的32例LGIAs的临床资料。结果 32例共32个LGIAs,其中大型动脉瘤（直径15~25 mm）22例,巨大型动脉瘤（直径≥25 mm）10例。32例中,23例球囊放置在颈内动脉近心端,9例放置在动脉瘤颈部;11例因术中造影示动脉瘤颈残留而调整动脉瘤夹位置,2例术中造影示载瘤动脉狭窄而调整动脉瘤夹位置,8例扩张球囊后动脉瘤并没有很好的解除压力而反向抽吸血流后成功夹闭;术后即刻造影显示完全或近完全闭塞率是100%。5例术中动脉瘤再破裂,出血量在400 ml以下,没有发生很严重的出血。术后13例出现短期神经功能障碍,6例表现出长期神经功能缺损。出院时GOS评分4~5分14例,1~3分18例。2例失访,2例死亡,剩余28例随访3~25个月（中位数12.5个月）,影像随访显示动脉瘤完全和近完全闭塞27例（96.4%）,1例复发;末次随访,改良Rankin量表评分0~2分23例,3~5分5例。结论 球囊辅助夹闭术治疗LGIAs是一种有效的方式,成功夹闭率高,病死率低,预后良好。     

前循环巨大动脉瘤的手术治疗

目的探讨手术治疗脑前循环巨大动脉瘤的方法，设计个体化治疗方案。方法回顾分析2001年1月至2005年3月间手术治疗的38例脑巨大动脉瘤方法和效果。分别采用：直接夹闭瘤颈12例；动脉瘤切除加脑血管重建5例；动脉瘤孤立术4例；颅内外动脉吻合伴或不伴血管内介入治疗14例；包裹1例；载瘤动脉阻断2例。结果术后恢复优良32例，重度病残4例，死亡2例。结论术前应充分评价脑血流动力学和侧支循环，个性化设计治疗方案，采用不同手术术式可取得良好预后；同时颅内外血管吻合术可有效改善颅内供血，确保动脉瘤的后续治疗；手术和血管内介入治疗的结合是今后巨大型动脉瘤治疗的一个方向。     

床突旁颈内动脉瘤的手术治疗

探讨床突旁动脉瘤的分型，以及各型的手术特点，以提高该动脉瘤的手术疗效。回顾性分析ｐ－ＩＣＡＡ１８例，其中颈眼动脉型７例；垂体上动脉型７例；颈内动脉腹侧型４例。手术方法包括动动脉瘤夹闭术１３例交；动脉瘤孤立术３例；夹闭＋包裹术２例；颈总动有吉轧＋动脉瘤包裹１例。     

微血管多普勒超声在颈内动脉瘤手术中的应用

目的 探讨微血管多普勒超声(MVD)在颈内动脉瘤手术中的应用.方法 采用探头频率20MHz、直径1.5 mm,对32例颈内动脉瘤患者(共计36个动脉瘤)进行动脉瘤夹闭前后血流动力学监测.术后血管造影进行评估.结果 所有患者均能在动脉瘤顶或瘤体部监测到涡流样或毛刺样血流信号、闻及杂音.动脉瘤夹闭术后即刻监测,发现载瘤动脉狭窄8例,闭塞1例;动脉瘤夹闭不全2例,均经调整瘤夹位置,显示载瘤动脉远段的血流频谱形态和音频信号正常,术后经DSA/CTA证实.以上情况的发生与动脉瘤大小及载瘤动脉有粥样硬化斑块有关.结论 MVD可作为颅内动脉瘤手术的常规检测方法,尤其对瘤颈粗、甚至无明显瘤颈的巨大型动脉瘤手术具有指导意义.