青少年与成年人正畸治疗后上颌切牙牙根吸收程度比较

目的:研究青少年与成年人正畸治疗后上颌切牙牙根吸收情况.方法:选择2014年5月-2016年8月于赤峰学院附属医院接受正畸治疗的患者,按年龄分为青少年组(12～17岁,32例)与成人组(18～35岁,36例).入组患者均接受全口直丝弓矫治技术,矫治结束后戴Hawley保持器,随访1年.治疗前(T1)、治疗结束时(T2)...     

External apical root resorption following orthodontic treatment

This study investigated the association of appliance type and tooth extraction with the incidence of external apical root resorption (EARR) of posterior teeth following orthodontic treatment. Pre- and posttreatment orthopantomograms were compared for 97 patients and a 4-grade ordinal scale used to measure EARR. The incidence of EARR was positively associated with tooth position (P < .001), appliance type (P = .038), and extractions (P = .001). This was observed in an overall analysis mutually adjusted for the effects of age at start of treatment, pretreatment overbite and overjet, use of headgear, tooth extraction, and type of appliance. The incidence of EARR was 2.30 times higher for Begg appliances compared with edgewise, and it was 3.72 times higher where extractions were performed.     

正畸矫治对根管治疗牙齿牙根吸收程度影响的CBCT研究

目的利用CBCT评价正畸治疗对根管治疗牙齿牙根吸收程度的影响。方法选择上下颌牙齿轻中度拥挤的成年患者16例,患者上颌前牙中至少有一颗已行根管治疗。使用0.558 8 mm槽沟的MBT托槽进行非拔牙矫治。于治疗前、后分别拍摄头颅CBCT,并分别测量根管治疗牙齿以及对侧同名牙齿的长度。采用配对t检验进行统计分析。结果 16例患者一共有18颗上颌前牙接受过根管治疗,其中包括6颗中切牙,8颗侧切牙,4颗尖牙。平均治疗时间为(18.3±2.6)个月。治疗前,已行根管治疗牙齿牙根平均长度(22.68±2.14)mm;治疗后,牙根平均长度为(21.98±2.05)mm。治疗前,对侧同名活髓牙牙根平均长度(22.61±2.01)mm;治疗后,牙根平均长度为(22.01±2.37)mm。两组差别无统计学意义。按照牙位单独分析,亦无统计学差异。结论利用CBCT能够很好地观察正畸治疗后牙根吸收的情况。在轻中度拥挤非拔牙的病例中,正畸治疗并不会增加上颌前牙已行根管治疗牙齿牙根吸收的风险。     

A radiographic analysis of external apical root resorption of maxillary incisors during active orthodontic treatment

External apical root resorption (EARR) is an undesirable consequence of orthodontic treatment. The purpose of this study was to measure the amount of EARR and to examine its clinical significance in maxillary incisors, during a 12-month active treatment period. A further aim was to examine the contribution of gender, treatment technique, treatment duration, and extraction of maxillary first premolars to EARR. The sample comprised 151 maxillary incisor teeth in 40 patients (16 males, 24 females) aged 12-22 years, with different malocclusions. Standard periapical radiographs, using the long-cone paralleling technique, were obtained before and 6 and 12 months after the start of treatment. Quantitative measurements for 80 central and 71 lateral maxillary incisors were performed separately and corrected for image distortion. Root length reduction was calculated in millimetres and in terms of the percentage of the original root length. Resorption of more than 1 mm at 12 months of active treatment was considered to be clinically significant. On average, the degree of EARR for the maxillary central incisors was 0.77 +/- 0.42 and 1.67 +/- 0.64 mm, respectively, during the 6- and 12-month follow-up (P < 0.001). For the lateral incisors, the degree of EARR was 0.88 +/- 0.51 and 1.79 +/- 0.66 mm, respectively (P < 0.001). Clinically significant resorption was found for 74 per cent of the centrals and 82 per cent of the laterals. No significant correlation was observed between EARR and treatment technique. EARR was found to be correlated with gender for the lateral incisors. The effect of treatment duration (P < 0.001) and premolar extraction (P < 0.001) was statistically significant for both tooth groups.     

External apical root resorption of posterior teeth in asthmatics after orthodontic treatment.

External apical root resorption is an undesirable sequela of orthodontic treatment, resulting in loss of tooth structure from the root apex. It has been proposed that systemic factors, such as the inflammatory mediators produced in asthma, may enter the periodontal ligament and act synergistically to enhance root resorption. The aim of this study was to determine if asthmatic patients exhibited a higher incidence or severity of external apical root resorption compared with healthy (no medical conditions) patients after fixed orthodontic treatment. Records were obtained from patients treated with fixed appliances; 99 were healthy and 44 had asthma. Using OPGs (panoral films), posterior external apical root resorption was measured on all first and second premolars, mesiobuccal and distobuccal roots of the upper first molars, and mesial and distal roots of the lower first molars, giving 4 measurements per quadrant. A 4-grade ordinal scale was used to determine the degree of external apical root resorption. Combined tooth analysis (adjusted for treatment time, appliance, and extractions) showed that asthmatics had significantly more external apical root resorption of posterior teeth after treatment compared with the healthy group (P =.0194). Tooth-by-tooth analysis (adjusted for treatment time, appliance, extractions, headgear, overbite, overjet, sex, and age at start of treatment) found the upper first molars were most susceptible to external apical root resorption. Although the incidence of external apical root resorption was elevated in the asthma group, both asthmatics and healthy patients exhibited similar amounts of grade 2 (moderate) and grade 3 (severe) resorption.     

External apical root resorption caused by orthodontic treatment: a review of the literature

Aim: External apical root resorption is a common consequence of orthodontic treatment. A number of treatment-related factors have been implicated in the pathogenesis of root resorption in orthodontic patients; however recent evidence suggests that genetic factors also play a major role in the development of this condition. Herein, we review prevalence, diagnosis and aetiology of root resorption with a particular emphasis on the effect of genetic variation and orthodontic forces, as well as discuss effective prevention strategies.     

Long-term follow-up of maxillary incisors with severe apical root resorption

The purpose of the study was to analyse the mobility of teeth with severe orthodontically induced root resorption, at follow-up several years after active treatment, and to evaluate mobility in relation to root length and alveolar bone support. Seventy-three maxillary incisors were examined in 20 patients, 10-15 years after active treatment in 13 patients (age 24-32 years) and 5-10 years after active treatment in seven patients (age 20-25 years). All had worn fixed or removable retainers; seven still had bonded twistflex retainers. Total root length and intra-alveolar root length were measured on intra-oral radiographs. Tooth mobility was assessed clinically according to Miller's Index (0-4) and the Periotest method. Crestal alveolar bone level, periodontal pocket depth, gingival, and plaque indices, occlusal contacts during occlusion and function, and dental wear were recorded. There was a significant correlation (P < 0.05) between tooth mobility, and total root length and intra-alveolar root length. No correlation was found between tooth mobility and retention with twistflex retainers. None of the variables for assessment of periodontal status, occlusion and function were related to total root length or tooth mobility. It is concluded that there is a risk of tooth mobility in a maxillary incisor that undergoes severe root resorption during orthodontic treatment, if the remaining total root length is < or = 9 mm. The risk is less if the remaining root length is > 9 mm. Follow-up of teeth with severe orthodontically induced root resorption is indicated.     

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目的    评价上中切牙正畸治疗后根吸收状况,探讨影响根吸收的相关因素。方法    从大连大学附属口腔医院正畸科2名资深医生2007年5月至2009年12月所完成的正畸病例中,随机选择233例（男85例,女148例）。分为成人组90例,平均年龄（21.73 ± 3.68）岁;青少年组143例,平均年龄（13.37 ± 1.81）岁。通过分析治疗前后的头颅侧位片观察上中切牙牙根形态与长度变化,评价上中切牙根吸收状况。结果    233例患者中的13例上中切牙发生了不同程度的根吸收,根吸收发生率为5.58%。成人女性拔牙矫治组的上中切牙根吸收程度高于青少年女性拔牙矫治组,差异有统计学意义（P < 0.05）。青少年组中,女性拔牙矫治患者的根吸收程度较男性拔牙矫治患者明显,差异有统计学意义（P < 0.05）。而是否拔牙,其上中切牙根吸收程度差异无统计学意义（P > 0.05）。结论    女性拔牙矫治患者治疗后的上中切牙根吸收发生率较高。正畸根吸收原因复杂,治疗前应详细分析各种根吸收易发因素,以减小正畸根吸收的发生和程度,维持正畸牙齿的健康。     

Root resorption in maxillary central incisors following active orthodontic treatment

The purpose of this study was to determine if apical root resorption associated with orthodontic treatment continues after the termination of active treatment (that is, the removal of fixed appliances). A sample of 45 subjects who had experienced root resorption during treatment was selected from the orthodontic clinic at the State University of New York at Buffalo. The length of the maxillary central incisors was measured from lateral cephalometric radiograms taken before treatment, after active treatment, and after retention. From these data, the resorption occurring during and after active treatment was calculated. The mean amount of root resorption during active treatment was 2.93 mm. The mean amount of root resorption during the posttreatment period was 0.1 mm. There was a statistical difference between these two means using the Student's t test at the 0.05 level of significance. The reliability coefficient comparing the first tracings and measurements in the 19 cases that were retraced and remeasured was r = 0.993. The data from this radiographic study support the hypothesis that root resorption associated with orthodontic treatment ceases with the termination of active treatment. There was also evidence to suggest that when posttreatment root resorption does occur, it is not necessarily associated with large amounts of root resorption during the active treatment period. It is more likely associated with other factors, such as traumatic occlusion and active force-delivering retainers.     

Contribution of cone beam computed tomography to the detection of apical root resorption after orthodontic treatment in root-filled and vital teeth

Objective:To investigate whether root-filled teeth are similar to vital pulp teeth in terms of apical root resorption (ARR) after orthodontic treatment.Materials and Methods:An original sample of cone beam computed tomography (CBCT) images of 1256 roots from 30 orthodontic patients were analyzed. The inclusion criteria demanded root-filled teeth and their contralateral vital teeth, while teeth with history of trauma had to be excluded to comply with exclusion criteria. CBCT images of root-filled teeth were compared before and after orthodontic treatment in a split-mouth design study. Tooth measurements were made with multiplanar reconstruction using axial-guided navigation. The statistical difference between the treatment effects was compared using the paired t-test.Results:Twenty posterior root-filled teeth and their contralaterals with vital pulp were selected before orthodontic treatment from six adolescents (two boys and four girls; mean [SD] age 12.8 [1.8] years). No differences were detected between filled and vital root lengths before treatment (P  =  .4364). The mean differences in root length between preorthodontic and postorthodontic treatment in filled- and vital roots were −0.30 mm and −0.16 mm, respectively, without any statistical difference (P  =  .4197) between them.Conclusion:There appears to be no increase in ARR after orthodontic treatment in root-filled teeth with no earlier ARR.     

External apical root resorption concurrent with orthodontic forces: the genetic influence

Root resorption is a pathological process of multifactorial origin related to the permanent loss of dental root structure in response to a mechanical, inflammatory, autoimmune or infectious stimulus. External apical root resorption (EARR) is a frequent clinical complication secondary to orthodontic tooth movement; apart from variables related to treatment, environmental factors and/or interindividual genetic variations can confer susceptibility or resistance to its occurrence. In this context, genetic predisposition has been described as an etiological factor, together with mechanical factors derived from orthodontic treatment. In recent years, international research groups have determined the degree of influence of some genetic biomarkers in defining increased/reduced susceptibility to postorthodontic EARR. The influences of the IL1 gene cluster (IL1B, IL1A, IL1RN, IL6), P2RX7, CASP1, OPG (TNFRSF11B), RANK (TNFRSF11A), Osteopontin (OPN), TNFα, the vitamin D receptor (TaqI), TNSALP and IRAK1 have been analyzed. The objective of the present review study was to compile and analyze the latest information about the genetic background predisposing to EARR during orthodontic treatment. Genetics-based studies along with other basic science research in the field might help to clarify the exact nature of EARR, the influence of genetic inheritance and possibly lead to the prevention or even eradication of this phenomenon during orthodontic treatment.     

Apical root displacement is a critical risk factor for apical root resorption after orthodontic treatment

Objectives:To identify risk factors for apical root resorption (ARR) of maxillary and mandibular incisors using mathematical quantification of apical root displacement (ARD) and multiple linear mixed-effects modeling.Materials and Methods:Periapical radiographs of maxillary and mandibular incisors and lateral cephalograms of 135 adults were taken before and after orthodontic treatment. ARR was measured on the periapical radiographs, and movement of central incisors was evaluated on the superimposed pre- and posttreatment lateral cephalograms. ARD was mathematically calculated from pretreatment tooth length, inclination change, and movement of the incisal edge. Linear mixed-effects model analysis was performed to identify risk factors for ARR, and standardized coefficients (SCs) were calculated to investigate the relative contribution of the risk factors to ARR.Results:Vertical ARD showed the highest SCs for both maxillary and mandibular incisors. Horizontal ARD showed the second highest SC for mandibular incisors but was not significantly correlated with the ARR of maxillary incisors. When horizontal and vertical ARDs were included in the mixed-effects model, the use of self-ligating brackets was significantly correlated with increased ARR of mandibular incisors.Conclusions:ARD is a critical factor for ARR after orthodontic treatment. Careful monitoring of ARR is recommended for patients requiring significant ARD of incisors.     

Apical root resorption after orthodontic treatment -- a retrospective study

The purpose of the study was to compare the incidence and severity of apical root resorption in patients treated with different orthodontic appliances and to evaluate the effect of treatment duration on the degree of apical root resorption. A further aim was to analyse the degree of apical root resorption in different tooth groups in patients presenting with root resorption. The sample consisted of 625 patients (269 males, 356 females) aged 8-16 years at the beginning of treatment. Active removable plates and fixed appliances were used most frequently. Following exclusion of poor quality radiographs, the final sample included 601 patients (348 females, 253 males). Root resorption in all tooth groups, except third molars, was evaluated from pre- and post-treatment panoramic radiographs. The correlation of root resorption with treatment modality and duration was studied using multinomial logistic regression analysis. Of the tooth groups, maxillary incisors showed apical root resorption most frequently, followed by the mandibular incisors. Root resorption was significantly correlated with fixed appliance treatment (P < 0.001). In addition, the duration of fixed appliances treatment was found to contribute significantly (P < 0.01) to the degree of root resorption. The mean duration of treatment in patients without root resorption was 1.5 years, whereas in those with severe resorption was 2.3 years. The most severe resorption was seen in the maxillary incisors and premolars. It is concluded that with a long duration of fixed appliance treatment, the risk of severe resorption increases. In patients where treatment is prolonged, a 6-month radiographic follow-up is recommended.     

Long-term follow-up of tooth mobility in maxillary incisors with orthodontically induced apical root resorption

The aim of the study was to evaluate tooth mobility in relation to root length and alveolar bone support in maxillary incisors 10-25 years after orthodontic treatment, and to monitor the development during 5 years in a sub-sample. Thirty-six patients, seven males and 29 females with one or more severely resorbed maxillary incisors, a total of 139 teeth, were examined. At re-examination, 11 patients were older than 40 years, 20 were between 30 and 39, and five younger than 30 years. Root length, alveolar bone height, and crestal alveolar bone level were measured on standardized intraoral radiographs. Tooth mobility was registered using Miller's index and the periotest method. Statistical analysis was undertaken using a t-test for dependent and independent samples, and chi-square tests for comparison of the relationship between the periotest values (PTVs) and the variables periodontal pocket depth, gingival index, incisal facets, interferences, and anamnesis. The majority of the teeth were stable. The correlation between root length and alveolar bone height was high, with minimal changes of marginal bone support. Extremely resorbed incisors with a root length less than 10 mm had significantly higher PTV than teeth with longer roots and greater bone support. In the sub-sample, tooth mobility was followed in 16 patients, two males and 14 females, with 62 maxillary incisors over a 5-year period. The PTV increased significantly on average, particularly in teeth with extreme resorption. Increasing mobility can be expected with age in teeth with extremely resorbed roots. Teeth with a root length > or =10 mm and a healthy periodontium remain stable.