PCNL MONOTHERAPY FOR RENAL CALCULI — AN INITIAL EXPERIENCE

Twenty nine cases of renal stone underwent treatment by way of percutaneous nephrolithotomy during a 6 month period. Of these, 13 patients had recurrent or residual stones. Majority of these stones were between 1-2 cm in size. A field operating table was modified for this purpose. In 26 cases the calyceal system was accessed through either of the inferior calyces. Twenty five of these patients underwent stone clearance in a single stage, 2 underwent two-stage surgery while there were 2 failures.KEY WORDS: Kidney calculi, Nephrostomy percutaneous     

HIGH ALTITUDE PULMONARY OEDEMA – AN EXPERIENCE IN EASTERN HIMALAYA

Three hundred and five cases of high altitude pulmonary oedema (HAPO) hospitalised in eastern Himalayan region have been analyzed. Incidence of HAPO was 5.5 per cent. Eighty per cent cases occurred during latter half of the year. Fifty six per cent of cases belonged to the third decade of life. HAPO cases occurred most commonly between the height of 2740 m to 5960 m. Eighty three per cent cases developed symptoms within 72 hours of induction to high altitude and 65.9 per cent suffered from the illness despite complete acclimatization. Breathlessness, headache and cough were the commonest symptoms. Tachycardia and tachypnoea was present in all cases. Twenty five per cent cases showed various ECG abnormalities. Mortality rate was 0.98 per cent.KEYWORDS: Altitude, ECG abnormalities, Cerebral oedema, Pulmonary oedema     

UPPER GASTROINTESTINAL MUCOSA IN CHRONIC RENAL FAILURE – AN ENDOSCOPIC AND HISTOLOGICAL EVALUATION

Over a three year period, 98 patients of moderate to severe chronic renal failure (S creatinine > 5 mg/dl) admitted in our centre were evaluated for upper GI lesions. All patients underwent upper GI endoscopy. In 68% upper GI mucosa was affected. Various lesions encountered were gastritis (25.5%), duodenitis (10.2%), gastroduodenitis (21.4%), telengiectasia (5.1%), and peptic ulcer in 6.1%. In 74 patients three biopsies, one each from antrum, fundus and duodenum were taken. 45.9% of these had chronic gastritis and 14.8% chronic duodenitis. Prevalence of H pylori on histology was 17.56%. 20 patients (9.6%) developed upper GI bleed during hospitalisation. In 17 (85%) patients, where endoscopy could be done, gastritis/duodenitis/oesophagitis were the common underlying lesions.KEY WORDS: Endoscopy, GI mucosa, GI bleed, H pylori.     

AN UNUSUAL CASE OF ASYMPTOMATIC APLASTIC RENAL DYSPLASIA

The postmortem examination of a 59-year-old man who had suffered from acute abdominal pain for two days revealed that the cause of death was peritonitis secondary to perforated peptic ulceration. During examination,it was found that the urinary tract was abnormal. Here,we report a postmortem finding of aplastic renal dysplasia of the kidney and malformation of Lhe urinary tract.     

ACUTE RENAL FAILURE – CHANGING TRENDS

A prospective study of 120 patients of acute renal failure was done at CH (EC) Calcutta to document the changing trends in the incidence and etiology of acute renal failure and to assess the prognostic factors. Mean age of patients was 33.7 ± 20.2 years. 75% had a medical risk factor. The etiological factors were volume depletion (13.3%), septicaemia (25.6%), falciparum malaria (16.6%), a transplant related renal failure (5.7%) and drugs (16.7%). Renal histology showed acute tubular necrosis to be the most common lesion (53.3%). In 13.3% patients who died with acute renal failure, associated infection and multisystem involvement was more common.KEY WORDS: Acute renal failure     

MIDDLE EAR RECONSTRUCTION – OUR EXPERIENCE

A comparative study of ossicular reconstrution using four different graft material was carried out on 40 patients as a second stage procedure from July 1989 to June 1991. The graft materials used were : aulologus ossicular bone graft, allogeneic ossicular bone graft, autologus cartilage and bio-compatible materials. All patients were observed for a period ranging from one to two years. Extrusion of ossicular graft was prevented by use of a lace of cartilage between the ossicular graft and neotympanic membrance. Satisfactory results were obtained with cartilage graft in 6%, allogeneic ossicles 70%, autologus ossicular graft 80% and bio-compatible materials 33.3%.KEY WORDS: Ossiculoplasty, Autologus and allogeneic ossicular graft, Total ossicular replacement prosthesis, Partial ossicular replacement prosthesis     

EARLY CARCINOMA TONGUE – SURGICAL OPTIONS

A retrospective analysis of 127 surgically treated cases of T-1, T-2 carcinoma of oral tongue during the period 1987-1990 was undertaken. 68.5 per cent (87) underwent hemiglossectomy and 31.5 per cent (40) underwent wide excision. There were loco-regional recurrences in 22 per cent (27). In the hemiglossectomy group 9 per cent (8 of 87) had local recurrences compared to 25 per cent (10 of 40) of wide excision group, (P = 0.01). Mean disease free survival was 40 months and 33 months for hemiglossectomy group and wide excision group respectively, (P = 0.006). It is seen that local recurrences are significantly less for the hemiglossectomy group compared to the wide excision group.KEY WORDS: Disease free survival, Early cancer, Recurrence, Surgery, Tongue     

INTRACARDIAC TUMOURS – EXPERIENCE WITH 12 CASES

Twelve cases of intracardiac tumours operated during the period 1975 to 1994 are presented. There were 8 males and 4 females in the age range of 18 years to 64 years. Tumours were located in the left atrium in 10 patients and in the right atrium in 2 patients. Standard cardiopulmonary techniques were followed. The right atrial tumours were approached through a right atrial incision while the left atrial tumours were approached through a bi-atrial trans-septal approach. One patient underwent a perineal urethrolithotomy for an impacted urethral calculus at the same sitting. Eleven of the tumour masses excised were myxomas confirmed on histopathology. The last patient, operated for synovial sarcoma of the left knee 2 years before, presented with a metastatic tumour mass in the left atrium. No deaths occurred in the series.KEY WORDS: Heart neoplasms, Heart surgery, Myxomas     

EFFECT OF CAPTOPRIL ON RENAL HEMODYNAMICS AND RENAL PROSTAGLANDINS IN EARLY TYPE Ⅱ DIABETIC PATIENTS WITH NORMO－OR MICROALBUM

ＥＦＦＥＣＴＯＦＣＡＰＴＯＰＲＩＬＯＮＲＥＮＡＬＨＥＭＯＤＹＮＡＭＩＣＳＡＮＤＲＥＮＡＬＰＲＯＳＴＡＧＬＡＮＤＩＮＳＩＮＥＡＲＬＹＴＹＰＥⅡＤＩＡＢＥＴＩＣＰＡＴＩＥＮＴＳＷＩＴＨＮＯＲＭＯ－ＯＲＭＩＣＲＯＡＬＢＵＭＩＮＵＲＩＡ￥ＸｉａｏＸｉｎｈｕａ...     

EXPERIENCE ON HLA TYPING FOR ALLOGENEIC MARROW TRANSPLANTATION IN 217 MEMBERS OF 30 FAMILIES

From April 1978 to Oct 1990, 217 members of 30 families who requiredallogeneic marrow transplantation were examined for HLA typing, with HLA standardantiserum and mixed lymphocyte culture (MLC). The following conclusions could bedrawn: (1) when the HLA-A, B, C loci between donor and recipient were identical, theD locus also was generally identical too, but, in some rare cases the HLA-A, B, C wereidentical while the D locus remained different detected by MLC SI which wassignificantly increased; (2) in addition to twin, the sib were the main candidates of donorsin allogeneic marrow transplantation, however, if the phenotype of children was compati-ble to that of their parents with no significant stimulation in MLC, the parents could alsobe considered as a donor; (3) if the HLA-A, B, C typing was identical between fatherand motaher, the parents can also be considered as an eligible donor. Using HLA-A, B,C, DR and D loci identical sibs as donor, 9 of 11 cases (aplastic anemia 9 cases andANLL-M2 2 cases who received allogeneic marrow transplantation) had the evidence ofengraftment. Much attention should be paid to the difference of the minorhistocompatibility antigens, such as sex associated antigen between donor and recipient, be-cause even in 11 cases with HLA-A, B, C, DR and D loci identical sibs as donors formarrow transplantation, 5 cases still had the manifestation of GVHD in various degree,4/5 died of severe GVHD.     

TRANSPLANTATION

8.1　Liver 205171　Study on hemostatic and coagulative variations during orthotopic liver transplantation/Wang Xuefeng(王学峰,Ruijin Hosp,Shanghai 2nd Med Univ,Shanghai200025)…∥Chin J Organ Transplant. - 2004, 25 (6).-339~342Objective　To investigate the hemostatic and coagu lative variations during orthotopic liver transplantation(OLT).Methods　The blood platelet count, coagulantand anti coagulant functions were assessed pre and intra operation of OLT.Results　During …     

TRANSPLANTATION

8 .1 Liver 207338 Rat liver ischemia and reperfusioninjury in UW, HTK and Celsior/Song Shaowei (宋少伟,Dept Gener Surg, 1st Clin Col ,Chin Med Univ,Shenyang110001)…∥ChinJ Organ Transplant .-2007 ,28(1) .-21 ~23Objective To study the changes of purine nucleoside phosphorylase (PNP) andrat liver exogenous hyaluronic acid (HA) absorption after cold storage and normothermic reper- fusionin University of Wisconsin ( UW) ,Celsior and histi- dine-tryptopan-ketoglutarate ( HTK) solutio…     

TRANSPLANTATION

Conelusion Advanee age was not the absolute eon-traindieation for kidney transplantation.It 15 partieu-lar imPortant to eonduet PreoPerative PreParation,Pe-rio详rative anesthesia and monitoring,the preventionand treatment of the PostoPerative eomplieations,andthe monitoring of the toxie and side effeets of im-munosuPPressive agent,ete.The卯stoPerative eom-plieations,espeeially lung infeetion,are the main deadfaetors for advaneed age CRF patients reeeiving kid-ney tran印lantation.3 refs. …     

TRANSPLANTATION

8.1Liver206317Relationshipbetweenintra abdominalhyper tensionandacuterenalfailureafterlivertransplanta tion/ShuMing(舒明,InstDigestSurgOrganTransplant CenterRuijinHosp,AffilHospShanghai2ndMedUniv,Shanghai200025)…∥ChinJOrganTransplant.-2006,27(1).-22～25ObjectiveToinvestigatetherelationshipbetween intra abdominalhypertension(IAH)andacuterenalfail ure(ARF)afterlivertransplantation.MethodsTheclin icaldataof62casesoflivertransplantationwereretrospectivelyanalyzed.Intra abdominalpress…     

TRANSPLANTATION

injury during the long mieroeeneapsulation periods.Methods Eighteen SD rats were divided into threegroups,6 rats eaeh.In groupA,fruetose was addedin to the perfusion solutions(20mmol/L).There wasno fruetose in group B and C.After isolation and mi-eroeneapsulation,the viability was tested.In vitro eul-ture,fruetose(10mmol/L)was added to eulturernedium in groupC,but not in grouP A and B.LDHleakage and TP of eulture were examined.ResultsThe survival of hepatoeytes in group A was obviously…     

TRANSPLANTATION

8.2 Kidney940606T】le renal blood now曲angeinrenalall。盯盯t rejeCtion:Eva luatedbyduPlex US and color DoPPler flow七na牙ing.Gao Yunhua(高云华),et al.Xi qiaoHOsP,3rd Milit Med Coll,Chongqing.ChinJUltrasound Med 1993;9(4):257一259 97 renal allograft Patients were examin一ed妙duPlex US and eolor DoPPler flowimag一ing(CDFI)for 127 times.Among theaeute rejeetion,ehronie rejeetion onnon一rejeetion eases.the CDFI resistiveindeX( Rl)and three,kinds of renal bloodf low veloeities wete a…     

TRANSPLANTATION

8。1 Uver2013”刀犯加巴枷份”t ofacuteliver公dl眼by谓11堪tn刃铭·脚朋回而,吧附平妞a重川牙理”犯,c,aU雌卿犯ical记~·,画c加甲at仪ytes厄1划艰Yel堪de(张阳德,卜抽tl佳钾tobdExlterio3】垠ReS公nter,O训吧sha 410008)…//C比nJS止g一2001.18(1)一47一49 倒代h视To investlgate the theral犯utlc effectof而-c联nca详iulat司s”哭犷11elc间bg叮祀北田记众”犯日〕巴。h卿to-Cyt巴on rats with aCute liver fail眠(Alf).扮kt抽山M-~臼声己a回he阳优哎以“hal、,es曰in wistar二ts(s”艰卿℃-ie),劝rats(山呢山eie),田记gu即ea pl…     

TRANSPLANTATION

lipid aeted as energy substrate in the ho-moiothermy eondition,pig liver organs wereperfused extraeorporeally through theV·portal with perfusion solution.In fixed peri-od of time the Perfusion solution from theliver was taken and analysed to detemine forliver bioehemieal funetion and observe theeoneentration and size of hepatoeellular mi-toehondria.Results In oxygen earrier perfu-sion solution the ammonia eoneentrationwas low,urea eoneentration was high,dam-age to mitoehondria was minimum and…     

TRANSPLANTATION

Objective: The experiment aimed at studying the possibility of transplantation ofpig's cryopreservated hepatocytes treating acutehepatic failure in Wistar rats. Methods: Porcinehepatocytes were cryopreserved in liquid