微波治疗慢性单纯性鼻炎205例

目的探讨微波治疗慢性单纯性鼻炎的疗效。方法采用EBH—IV型耳鼻喉综合微波治疗仪治疗慢性单纯性鼻炎205例，之后用达芬霖液体喷雾剂喷鼻1—2周，1个月后检查统计分析治疗结果。结果治愈181例(88．3％)，好转22例(10．7％)，无效2例(1．0％)，总有效203例(99．0％)。结论应用微波治疗慢性单纯性鼻炎具有操作简单、无出血及焦痂和治疗效果好等优点。     

复方氧氟沙星溶液与常用疗法治疗鼻部炎性疾病的疗效对照观察

应用复方氧氟沙星溶液对 130例鼻部疾病患者进行治疗 ,结果显示 :该溶液对急性鼻炎、慢性单纯性鼻炎、慢性鼻窦炎、萎缩性鼻炎的有效率分别为 91%、86 %、91 3%、10 0 %。应用常用疗法对 10 0例鼻部疾病患者进行治疗 ,结果显示对上述四种疾病的有效率分别为 85 %、88%、5 8 3%、78%。复方氧氟沙星溶液治疗慢性鼻窦炎、萎缩性鼻炎的有效率明显大于常用方法 (P <0 0 5 )。治疗慢性单纯性鼻炎与急性鼻炎的有效率与常用方法无明显差异 (P >0 0 5 )。     

微波热凝治疗慢性鼻炎32例疗效观察

我科自 1 997年以来 ,用微波热凝术治疗慢性鼻炎 32例 ,临床观察疗效确定 ,现报告如下。1　资料与方法1 1　资料32例中 ,男 2 1例 ,女 1 1例。年龄 1 8～ 5 0岁 ,平均 36岁。病程 3～ 1 5年。慢性单纯性鼻炎 1 5例 ,慢性肥厚性鼻炎 1 0例 ,血管运动性鼻炎 7例。1 2　治疗方法1 %地卡因 2 0mL加 1‰肾上腺素 2mL制成棉片 ,表面麻醉和收缩鼻腔黏膜 2 0min ,采用微波多功能治疗机正大WB - 1 0 0 ,调至功率 30W ,时间 4s ,在鼻镜直观下 ,用单极探头置于下鼻甲下缘黏膜 ,由后向前在脚踏开关控制下选择 4～ 6点 ,使粘膜肥厚处组织凝固、收缩 ,…     

鼻炎电疗仪治疗慢性鼻炎、变应性鼻炎近期疗效观察

目的　探讨治疗慢性单纯性鼻炎、慢性肥厚性鼻炎、变应性鼻炎的新疗法。方法　使用英特医疗器械研究所研制的YT2 0 0 0 A型鼻炎电疗仪在门诊局麻下治疗上述鼻炎 95例。结果　 95例患者治愈 5 5例 ,显效 2 5例 ,好转 11例 ,无效 4例 ,总有效率 95 8%。结论　YT2 0 0 0 A型鼻炎电疗仪治疗上述鼻炎疗效显著 ,无明显并发症 ,操作简单、安全可靠 ,值得临床推广应用     

盐酸羟甲唑啉鼻腔喷雾剂的临床疗效

传统用麻黄素治疗鼻炎、鼻窦炎患者的鼻塞症状虽作用迅速但副作用较多。我们用盐酸羟甲唑啉鼻腔喷雾剂 (商品名为达酚霖 )治疗并与 1 %麻黄素滴鼻液进行了比较。1　资料与方法1 .1　临床资料　随机将 1 2 0例分为两组 ,达酚霖组 60例 ,麻黄素组 60例 ,达酚霖组中慢性肥厚性鼻炎 36例 ,单纯性鼻炎1 8例 ,鼻窦炎鼻息肉 6例。麻黄素组中慢性肥厚性鼻炎 42例 ,单纯性鼻炎 1 1例 ,鼻窦炎鼻息肉 7例。 1 0岁以下 ,高血压、心脏病、达酚霖过敏者除外。1 .2　方法　患者全身疗法相同 ,达酚霖喷鼻每日 2次 ,每次每鼻孔 1次 ,对照组用 1 %麻黄素 ,治疗…     

鼻炎治疗仪治疗鼻炎的保护材料改进及效果观察

我科采用 YT2 0 0 0 - A型鼻炎电疗仪治疗鼻炎 ,收到了较好的效果。现介绍如下。1　临床资料及方法1.1　观察对象　 2 0 0 0年 5月至 2 0 0 3年 4月在我院门诊治疗的 91例病人 ,随机分为常规组和改进组。常规组 4 5例 ,其中过敏性鼻炎 17例 ,肥大性鼻炎 16例 ,慢性单纯性鼻炎 12例。改进组 4 6例 ,其中过敏性鼻炎14例 ,肥大性鼻炎 2 1例 ,慢性单纯性鼻炎 11例。1.2　方法1.2 .1　常规方法　先给予下鼻甲 1%的卡因棉片行鼻腔粘膜表面麻醉 ,再用 7号长针刺入双下鼻甲粘膜2～ 3cm,用棉片包绕针体 ,塞入前鼻孔以保护鼻前庭皮肤。通电治疗 15分…     

微波小功率治疗鼻炎临床观测

我们自 1998年起使用成都锦江微波电器厂生产的ＷＢ- 10 0Ｂ微波多功能治疗机治疗单纯性鼻炎、肥厚性鼻炎、常年变应性鼻炎 179例 ,疗效良好 ,报告如下。1　资料与方法1 1　临床资料　本组男 10 9例 ,女 70例 ,16～ 5 7岁 ,平均37 2岁 ,发病时间 6个月～ 2 5年 ,平均 3 7年。单纯性鼻炎30例 ,常年变应性鼻炎 6 3例 ,肥厚性鼻炎 86例 ,39例合并副鼻窦炎 ,13例耳咽管功能不良 ,32例主诉打鼾症状明显。1 2　方法1 2 1　鼻炎合并副鼻窦炎患者先用青霉素 80万Ｕ 庆大霉素 8万Ｕ 1%氯麻液 5ｍｌ 生理盐水 2 0ｍｌ经鼻雾化吸入 ,每日 2次共 5ｄ …     

微波热凝治疗慢性肥厚性鼻炎临床分析

慢性肥厚性鼻炎是耳鼻喉科常见的多发病 ,传统的治疗方法很多 ,但临床疗效不一 ,且各有利弊。1 998年 9月以来 ,我科应用WB 1 0 0型微波治疗仪(成都锦江微波电器厂产 )热凝治疗慢性肥厚性鼻炎患者 4 0例 ,并与 1 998年 8月以前应用 80 %甘油行下鼻甲粘膜硬化法治疗的 4 0例进行对比 ,现将结果报道如下。1　资料与方法1 1　一般资料 :微波组 4 0例中 ,男 2 8例 ,女 1 2例 ;年龄 1 6～ 5 0岁 ,平均年龄 32 0岁。病程 2～ 30年 ,平均 1 0 5年。硬化组 4 0例中 ,男 32例 ,女 8例 ;年龄 1 8～ 5 4岁 ,平均 34 5岁。病程 2～ 30年 ,平均1 1 5…     

慢性肥厚性鼻炎微波治疗的疗效观察

目的 观察慢性肥厚性鼻炎微波治疗的疗效.方法 对66例慢性肥厚性鼻炎患者行微波治疗,统计有效率,分析鼻塞等症状改善不理想原因.结果 全部病例随访1～2年.微波治疗治愈60例,治愈率91%; 好转6例,好转率9%,总有效率100%.结论 微波治疗的有效率与手术适应证的正确选择有关.慢性肥厚性鼻炎微波治疗时间短、创伤小、恢...     

微波治疗慢性单纯性鼻炎

慢性单纯性鼻炎是耳鼻喉科常见的多发病，传统治疗方法很多，但临床疗效不一，且各有利弊。1997年7月以来，我科应用WTK微波治疗仪(长春生产)热凝治疗慢性单纯性鼻炎患者120例，取得良好效果，现报告如下。     

慢性肥厚性鼻炎的四种改进术式疗效比较

目的比较四种改进术式与传统方法在慢性肥厚性鼻炎治疗中的优劣。方法将2010年6月~2011年1月本科诊断为慢性肥厚性鼻炎的280例患者分为四组。A组：82例行微波治疗;B组：83例行低温等离子消融治疗;C组：65例行下鼻甲骨-黏膜剥离术治疗;D组：50例行下鼻甲骨骨折术治疗。结果四组中A组短期疗效好,B组创伤小、恢复快、长期效果好,C组长期效果好,但创伤大、操作稍复杂,D组长期效果好、创伤小、操作简单。A、B、C、D组6个月后总有效率分别为60.98%、84.34%、86.15%、82.00%。A组长期总有效率与其他比较差异均有高度统计学意义（均P〈0.01）。其他三组（B、C、D）间比较差异无统计学意义（P〉0.05）。四组均无明显后遗症。结论低温等离子消融及下鼻甲骨骨折治疗慢性肥厚性鼻炎有良好临床疗效,可于临床广泛应用。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.