共查询到20条相似文献,搜索用时 218 毫秒
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目的:研究大枣的炮制方法。方法:运用7种不同的炮制方法对大枣进行炮制,采用紫外可见分光光度法测定各炮制品中总黄酮的含量。结果:净制,炒黄法,炒焦法,炒炭法,砂烫法,蒸法,煮法7种炮制方法比较,各种炮制方法测得的总黄酮含量有变化,砂烫法中总黄酮含量相对较高且吸收峰图谱几乎与净制品和芦丁对照品的一致。结论:砂烫法为大枣较佳的炮制方法。 相似文献
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目的:考察金樱根不同炮制品中没食子儿茶素和儿茶素含量的变化。方法:采用RP-HPLC法测定不同炮制品金樱根的没食子儿茶素和儿茶素的含量。结果:没食子儿茶素含量为:蜜炙品(0.8495mg·g-1)>盐炙品(0.8317mg·g-1)>黑豆汁制品(0.7330mg·g-1)>醋炙品(0.6853mg·g-1)>生品(0.6520mg·g-1)>炒炭品(0.5032mg·g-1);儿茶素含量为:盐炙品(10.697mg/g)>醋炙品(10.449mg/g)>黑豆汁制品(9.486mg/g)>蜜炙品(8.394mg/g)>生品(6.116mg/g)>炒炭(4.235mg/g)。结论:蜜炙、盐炙、黑豆汁制、醋炙这4种炮制方法均可提高金樱根中没食子儿茶素和儿茶素的含量,而炒炭炮制方法降低金樱根中没食子儿茶素和儿茶素的含量。 相似文献
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目的:研究干姜经不同的炮制方法对其主要化学成分6-姜酚含量的影响。方法:采用HPLC测定炒黄、炒炭(清炒、闷煅)、麸炒、砂炒等不同炮制工艺后干姜中6-姜酚含量的变化。结果:传统炮制中6-姜酚的含量从大到小依次为:炒黄>麸炒>干姜>砂炒>炒炭>闷煅。结论:炮制火候和条件是影响干姜中6-姜酚含量的主要因素,炒黄的温度条件相对最低,其6-姜酚含量最高为8.57 mg·g-1,麸炒温度条件比炒黄稍高一些,其6-姜酚含量为8.14 mg·g-1,说明一定受热程度有利于提高干姜中6-姜酚含量。 相似文献
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目的 :考察不同炮制方法对莪术挥发油的影响。方法 :对三种不同来源的不同炮制品中挥发油含量进行测定。结果 :挥发油含量高低依次为 :生品 >炒制品 >醋制品 >酒制品。结论 :为筛选莪术合理的炮制工艺提供了实验依据。 相似文献
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目的:优化杜仲叶中绿原酸的分离纯化工艺,并探讨其抗氧化活性。方法:以绿原酸提取率为指标,比较铅沉淀、石灰乳沉淀、溶剂萃取、壳聚糖絮凝除杂对粗提物的分离效率,并考察7种大孔树脂对绿原酸的吸附性能,还研究了杜仲叶绿原酸提取物的抗氧化活性。结果:最佳分离除杂方法为壳聚糖絮凝除杂法,最佳树脂为NKA-9型大孔树脂,上柱前粗提物绿原酸含量为2.54%,经大孔树脂纯化后产品中绿原酸含量达到42.43%,提高了16倍。结论:壳聚糖絮凝除杂法能很好分离除杂,NKA-9型大孔树脂对杜仲叶绿原酸有较好纯化效果。杜仲叶绿原酸提取物抗氧化活性强于绿原酸标准品。 相似文献
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Investigation into the mechanism of Eucommia ulmoides Oliv. based on a systems pharmacology approach
Yan Li Chunxiao Han Jinghui Wang Wei Xiao Zhenzhong Wang Jingxiao Zhang Yinfeng Yang Shuwei Zhang Chunzhi Ai 《Journal of ethnopharmacology》2014
Ethnopharmacology relevance
Though Traditional Chinese Medicine (TCM) has long been playing a significant role in the maintenance of health for people in Asia as well as many other places, the mechanism of its action still remains ambiguous for most of the plants used in TCM, such as Eucommia ulmoides Oliv., a kind of herb that is widely used to help regulate hypertension and the immune system nowadays. However, its functioning mechanism is still unknown. Thus it is necessary to exploit the mechanism of Eucommia ulmoides Oliv.Methods
A systems pharmacology approach combining drug-likeness evaluation, oral bioavailability prediction, multiple drug targets prediction as well as network pharmacology techniques has been used.Results
This comprehensive systematic approach helps successfully to identify 41 candidate compounds contained in Eucommia ulmoides Oliv. while 39 potential targets hit by these ingredients and helps to uncover the synergistic mechanism of action on a systematic level.Conclusions
Our work successfully explains the mechanism of the efficiency of Eucommia ulmoides Oliv. for the treatment of hypertension and enhancing immune. These results not only provide a new insight for the understanding of the chemical and pharmacological basis of Eucommia ulmoides Oliv., but also provide an efficient way for drug discovery from herbal medicine. 相似文献15.
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A comparison of the contents of 7 trace elements (Zn, Mn, Cu, Fe, Ca, P, Pb) in Eucommia ulmoides and its processed products has been made, and the significance of processing Eucommia ulmoides is discussed in light of the experimental results. 相似文献
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杜仲总多糖对环磷酰胺致免疫低下小鼠的影响 总被引:1,自引:0,他引:1
目的研究杜仲总多糖对环磷酰胺致免疫低下小鼠的影响。方法应用环磷酰胺建立免疫低下小鼠模型,给予不同剂量杜仲总多糖后,测定小鼠体重、胸腺指数、脾指数、腹腔巨噬细胞吞噬率、吞噬指数等指标。结果300g杜仲原药材经提取分离得9.3g多糖干品。应用环磷酰胺后,小鼠体重、胸腺指数、腹腔巨噬细胞吞噬率、吞噬指数均降低。杜仲总多糖能减轻环磷酰胺致小鼠体重的下降,升高免疫低下小鼠胸腺指数,明显增加小鼠腹腔巨噬细胞吞噬率、吞噬指数(P<0.01)。与空白组比较,杜仲总多糖还能提高正常小鼠的脾指数(P<0.05)。结论杜仲总多糖能够较好地增强小鼠免疫功能。 相似文献