肝素注射联合山莨菪碱按摩治疗新生儿硬肿症效果观察

目的 探讨肝素皮下注射联合山莨菪碱注射液局部按摩治疗新生儿硬肿症的效果.方法 将78例硬肿症新生儿随机分为观察组(40例)和对照组(38例),对照组行常规治疗,观察组在此基础上用小剂量肝素10μp/(kg·d)皮下注射,联合山莨菪碱注射液按摩硬肿部位,2次/d.结果 两组治疗效果、体温回升时间、硬肿消退时间比较.差异有统计学意义(P<0.05,P<0.01).结论 肝素皮下注射联合山莨菪碱注射液局部按摩治疗新生儿硬肿症有效,且方法简单安全.     

推拿辅助治疗新生儿硬肿症效果观察

新生儿硬肿症是新生儿死亡的重要原因之一。为降低病死率 ,提高治愈率 ,我院于 2 0 0 0年 1月至 2 0 0 2年 9月对34例新生儿硬肿症患儿在综合治疗的基础上采用推拿辅助治疗 ,效果显著 ,现报告如下。1　资料与方法　　一般资料 :34例中 ,足月儿 10例 ,早产儿 2 4例。体重≥ 2 5 0 0 g 13例 ,<2 5 0 0g 2 1例。根据新生儿硬肿症的诊断标准[1] ,按硬肿范围、腋肛温差、器官功能改变 ,分为轻、中、重度。轻度 12例 ,中度 18例 ,重度 4例。合并窒息12例 ,肺炎 13例 ,败血症 3例。　　方法 :应用常规综合治疗 ,如复温、暖箱保暖、给氧、补充液体 ,…     

湿热敷治疗新生儿硬肿症效果观察

将96例新生儿硬肿症患儿随机分为对照组(46 例)和观察组(50 例)。对照组置入暖箱,观察组在此基础上对患儿双下肢进行湿热敷。结果观察组复温时间(12.00±3.64) h、硬肿消失时间(3.02±1.49) d;对照组复温时间(20.26±5.63) h、硬肿消失时间(4.03±1.45) d,两组比较,差异有显著性意义(均P<0.01)。提示暖箱复温配合湿热敷是治疗新生儿硬肿症的有效方法。     

新生儿硬肿症138例护理体会

<正> 新生儿硬肿症是新生儿疾病中很常见的一个症候群,主要由寒冷损伤所致,以早产、窒息、感染的新生儿常见。我院儿科1996年～2001年间共收治138例新生儿硬肿症,采取一系列综合护理,取得了很好的临床疗效,现总结如下。 1 临床资料 1.1 一般资料:本组138例,男76例,女62例。发生在冬春寒冷季节者98例,非寒冷季节40例,轻度硬肿112例,中度硬肿22例,重度硬肿4例。     

甲状腺激素佐治新生儿重度硬肿症

本文用甲状腺片每日４ｍｇ／ｋｇ佐治２０例新生儿重度硬肿症，治疗５－７日，结果显示佐治组体温恢复至正常，硬肿开始消通及完全消退时间均较对照组明显缩短，病死率显著下降，未发现甲状腺激素中毒反应，停用一周后查血清Ｔ３，Ｔ４，ＴＳＨ均正常，故提出甲状腺激素激素短时间佐治新生儿重度硬肿症是安全有效的，同时对新生儿硬肿症发生ＮＴＩ的机制进行了探讨。     

快速复温辅助治疗新生儿硬肿症的护理

１９９６～１９９８年我科采用快速复温法辅助治疗新生儿硬肿症２２例，效果满意。报告如下。１　临床资料２２例中男１１例，女１１例；胎龄最小３１周，最大４０周，平均３４周；体重１０００～３６８５ｇ，平均２０４６ｇ；体温（肛温）最低３１．４℃，最高３６．０℃，平均３３．４℃。因早产窒息所致本病１２例，感染所致６例，寒冷刺激所致４例。其中有１８例为早产儿，１２例并发窒息，５例并发肺炎，１例并发败血症，１例合并肺出血、呼吸窘迫综合征。硬肿范围＜２０％１９例，２０％～５０％２例，＞５０％１例。根据评分标准［１…     

红花浸液推拿辅助治疗新生儿硬肿症

目的探讨红花浸液推拿辅助治疗新生儿硬肿症的效果。方法将50例新生儿硬肿症患儿随机分成观察组和对照组各25例。对照组采用常规综合治疗,观察组在此基础上加用红花浸液推拿硬肿处皮肤。结果两组总有效率、硬肿消退时间、体温回升时间比较,差异有显著性意义（均P〈0.01）。结论红花浸液推拿辅助治疗新生儿硬肿症疗效确切,安全。     

1例重症新生儿硬肿的护理体会

目的:探讨对新生儿硬肿症的护理.方法:对我科1例例新生儿硬肿症患儿根据引起本病的危险因素、临床表现及新生儿复温、合理喂养等护理进行回顾性分析[5].结果:通过控制感染、对症治疗、支持治疗,效果显著,治愈率达99％.结论加强护士预防和治疗新生儿硬肿症发生的关键之一.     

山莨菪碱对体外循环心脏手术后白细胞变形力的影响

为观察山莨菪碱对体外循环（ＣＰＢ）心脏手术后病人白细胞变形能力（ＬＤ）的影响，进一步探讨该药改善微循环的机制。将１６例体外循环下心脏手术病人均分为实验、对照组。实验组于术后６０分钟静脉注射山莨菪碱０．２ｍｇ／ｋｇ。两组分别于术前、术后６０、给药后３０、６０分钟采外周血，测定白细胞变形力。结果显示，ＣＰＢ术后６０分钟两组白细胞变形力均明显降低（Ｐ＜０．０１），组间差异无显著性（Ｐ＞０．０５）。实验组给药后３０分钟ＬＤ高于对照组（Ｐ＜０．０１），但两组仍低于术前（Ｐ＜０．０１），给药后６０分钟实验组ＬＤ恢复至术前水平（Ｐ＞０．０５），明显高于对照组（Ｐ＜０．０１）。结论：ＣＰＢ术后ＬＤ降低，山莨菪碱对微循环的改善除作用于血管平滑肌及内皮外，提高ＬＤ亦起着重要作用     

山莨菪碱治疗小儿秋季腹泻的疗效观察

目的评价山莨菪碱治疗急性轮状病毒肠炎的效果。方法选择64例急性轮状病毒肠炎患儿随机分组,治疗组33例给予口服山莨菪碱,对照组31例给予口服维生素B1。结果治疗6d后,治疗组治愈54.5,改善36.4,无效9.1,总有效率90.9;对照组治愈45.2,改善35.5,无效19.3,总有效率80.6。总有效率比较差异有统计学意义（P〈0.01）。结论山莨菪碱能改善婴幼儿秋季腹泻症状,缩短病程。     

Absence of Effect of Heparin on Insulin Secretion

Bioartificial pancreatic devices containing isolated islets of Langerhans have been designed, in which the blood of the recipient circulates in contact with an artificial membrane, protecting the islets against immune rejection. This system assumes that heparin, required to prevent blood clotting, does not alter insulin secretion. However, heparin has been reported to inhibit in vitro insulin secretion by rat islets and to suppress in vivo insulin secretion in dogs. Therefore, the following evaluation was made on the effect of different heparin preparations on insulin secretion. (a) Isolated rat islets of Langerhans were perfused or incubated in the absence or presence of 20 micrograms/ml heparin; insulin secretion in response to a stimulation by glucose 20 mM was not altered by the presence of heparin. (b) Insulin secretion by an insulin-secreting cell line (RINm5F) in response to leucine and theophylline was not suppressed by heparin up to 100 micrograms/ml concentration. However, an inhibitory effect was observed at 200 micrograms/ml, which is 100 times higher than the heparin concentration commonly used for therapeutic use. (c) Neither in normal rats nor in dogs did heparin alter portal plasma insulin levels and the increase in plasma insulin following an intravenous injection of glucose. In conclusion, these data do not confirm the formerly observed inhibitory effect of heparin, which can therefore be used for the in vivo evaluation of a bioartificial pancreas.     

穴位运经治疗面瘫疗效观察

目的探讨穴位运经治疗面瘫的疗效。方法将73例面瘫患者随机分为观察组（37例）和对照组（36例），观察组采用推按运经治疗仪的脉冲电流刺激穴位治疗，对照组采用传统针刺穴位治疗。结果两组治疗效果比较，差异无显著性意义（P〉0．05）。结论采用穴位运经治疗面瘫，是一种无创安全、有效的治疗方法。     

云南白药联合山莨菪碱治疗化疗性静脉炎效果观察

目的 探讨云南白药联合山莨菪碱治疗化学性静脉炎的临床效果。方法 将行静脉化疗发生Ⅲ、Ⅳ级静脉炎60例患者随机分成观察组与对照组各30例，观察组将云南白药1g与山莨菪碱10mg调成糊状适量均匀敷于静脉炎处，用无菌纱布包扎，每日换药1次，直至治愈。对照组采用庆大霉素8万u、地塞米松5mg加生理盐水5m1纱布湿敷，予保鲜膜包裹，每6小时加药1次，直至治愈。结果 两组均100％治愈，对照组治愈时间为（14．53±6．40）d，观察组为（6．574±2．57）d，两组比较，差异有显著性意义（t=6．324，P〈0.01）。结论 云南白药联合山莨菪碱治疗化疗所致Ⅲ、Ⅳ级静脉炎能显著缩短治愈时间。     

云南白药联合山莨菪碱治疗化疗性静脉炎效果观察

目的 探讨云南白药联合山莨菪碱治疗化学性静脉炎的临床效果.方法 将行静脉化疗发生Ⅲ、Ⅳ级静脉炎60例患者随机分成观察组与对照组各30例,观察组将云南白药1 g与山莨菪碱10 mg调成糊状适量均匀敷于静脉炎处,用无菌纱布包扎,每日换药1次,直至治愈.对照组采用庆大霉素8万U、地塞米松5 mg加生理盐水5 ml纱布湿敷,予保鲜膜包裹,每6小时加药1次,直至治愈.结果 两组均100%治愈,对照组治愈时间为(14.53±6.40)d,观察组为(6.57±2.57)d,两组比较,差异有显著性意义(t=6.324,P＜0.01).结论 云南白药联合山莨菪碱治疗化疗所致Ⅲ、Ⅳ级静脉炎能显著缩短治愈时间.     

Acute Effect of Standard Heparin Versus Low Molecular Weight Heparin on Oxidative Stress and Inflammation in Hemodialysis Patients

Objective. Atherosclerotic cardiovascular diseases caused by traditional and non-traditional risk factors are the most common cause of morbidity and mortality in hemodialysis patients. Recently, much interest has been focused on non-traditional factors, such as oxidative stress, inflammation, and endothelial dysfunction. Hemodialysis patients are not only exposed to oxidative stress but also to inflammation. Although anticoagulants are the most frequently used drugs in hemodialysis patients, their effect upon oxidative stress and inflammation in dialysis patients are still unknown. Methods. Thirty-three hemodialysis patients were randomized into three groups. Group 1 received standard heparin while group 2 received low molecular weight heparin during the dialysis therapy. Group 3 (control group) did not receive any anticoagulant agent. Investigators were blinded to the therapy. Serum concentrations of oxidative stress and inflammation markers, including C-reactive protein, tumor necrosis factor alpha, superoxide dismutase, and malondialdehyde, were measured before and after dialysis session. Results. The oxidative stress and inflammation markers were significantly increased in groups 1 and 3 (p < 0.05 for each) compared to their baseline values. In contrast, baseline and end-treatment values of the oxidative stress and inflammation markers were comparable in the group 2 (p > 0.05). Conclusion. These findings indicate that the type of anticoagulants may take a role in the acute effect of hemodialysis upon oxidative stress and inflammation markers. A comparison of the groups revealed that low molecular weight heparin decreased the oxidative stress and inflammation, whereas standard heparin increased the oxidative stress and inflammation. Low molecular weight heparin appears to have an additive benefit for hemodialysis patients.