CT对原发性肠脂垂炎的诊断价值分析

目的：探讨CT对原发性肠脂垂炎的诊断价值。方法回顾性分析11例原发性肠脂垂炎的CT影像学资料,观察病灶的形态、大小、密度、部位及强化表现。结果与压痛部位一致的结肠壁旁肿块影,脂肪密度,呈梭形或卵圆形,5例边缘清晰,6例边缘模糊。肿块最大径2.1 cm~5.8 cm,中心密度低于四周密度,增强后呈环状强化。其中2例位于盲肠旁,1例位于升结肠旁,3例位于降结肠旁,5例位于乙状结肠旁。结论CT能及时发现肠脂垂炎的病灶并精确定位,有典型的影像学表现,对诊断及鉴别诊断具有重要价值。     

急性原发性肠脂垂炎的CT诊断

目的 探讨急性原发性肠脂垂炎的CT诊断及鉴别诊断.方法 回顾性分析成都市西区医院2011年12月至2016年7月收治的7例急性原发性肠脂垂炎的临床及CT资料,其中3例经手术及病理证实.结果 7例患者中3例位于升结肠旁,4例位于乙状结肠旁.7例CT平扫表现为结肠旁卵圆形脂肪密度结节影,边缘呈薄层环状稍高密度影,5例周围脂肪间隙内显示条索状或斑片状渗出影,7例患者病灶中心均可见点状或线状稍高密度影;增强后病灶呈环状强化;邻近腹膜增厚4例,局部结肠壁水肿、增厚3例.结论 急性原发性肠脂垂炎具有特征性CT表现,正确诊断可以避免不必要的外科手术治疗.     

急性原发性肠脂垂炎的MSCT特征及临床诊断价值

目的 分析急性原发性肠脂垂炎(APEA)的多层螺旋CT(MSCT)影像特征,探讨其临床诊断价值。方法 回顾分析我院12例经MSCT检查和随访诊断为APEA患者的完整的临床和影像学资料,观察病灶的发病部位、形态、密度、大小、周围脂肪组织、邻近腹膜及肠壁等改变。结果 12例APEA中,病灶位于乙状结肠旁4例,降结肠旁4例,,升结肠旁1例,结肠脾曲1例;所有病灶均为单发, 6例呈圆形或卵圆形,4例呈梭形,2例呈戒指样改变;病灶均呈中心密度较低、边缘密度较高的脂性密度, 8例病灶中心呈点状、线样或圆形稍高密度影的“中心点征”,12例均呈边缘环形稍高密度;病灶直径约1.8cm～3.6cm;2例周围脂肪间隙模糊,可见絮片状稍高密度渗出影;6例病灶可见邻近腹膜增厚,仅2例病灶相邻结肠壁增厚, 1例增强病灶边缘呈环形强化。结论 APEA的MSCT影像学表现具有一定特征性(圆形、卵圆形、梭形或戒指样脂肪密度团块,“中心点征”及边缘环形稍高密度伴或不伴周围炎性渗出改变),联合多平面重建能准确诊断APEA并能清楚显示邻近腹膜及肠壁情况,为临床诊断提供重要价值。     

原发性肠脂垂炎的MSCT特征表现

目的探讨多层螺旋CT诊断原发性肠脂垂炎的特征表现,提高对该病的认识。方法搜集我院2012至2016年间由CT提示并之后随访诊断为肠脂垂炎的24例患者临床及影像学资料,分析病变与结肠的位置关系、病变的大小、脂肪中心是否有高密度存在、邻近肠壁改变等征象。并对5例复诊患者的CT与第一次CT进行比较。结果肠脂垂炎最常见的发病部位为乙状结肠周围,最常见的位置为结肠前方;各病灶均表现为邻近肠壁的类圆形脂肪密度病灶,边缘有完整或不完整环形软组织密度,13例病变内部可见点状或小片状软组织密度影;24例病灶周围均可见模糊渗出,21病变邻近腹膜可见不同程度增厚;仅2例病灶局部肠壁增厚。在5例随访患者的CT图像上观察到病变大小、内部密度变化及内部高密度征的大小都随时间发生改变。结论肠脂垂炎具有一定的临床和影像学特征,CT能够发现病变,确定病变部位、范围及周围肠管表现,对临床诊断及治疗有指导意义     

多层螺旋CT检查用于原发性肠脂垂炎诊断的价值

目的 分析原发性肠脂垂炎的多层螺旋CT表现,探讨多层螺旋CT检查的诊断价值.方法 回顾性分析20例原发性肠脂垂炎的多层螺旋CT资料,观察病灶的形态、大小、密度、部位及周围表现.结果 20例病灶呈现戒指样或卵圆形;大小为1.5 cmx2.5 cm～3.1 cmx5.0cm;病灶呈现脂肪性密度,肿块中心密度低,周围密度高：病灶位于结肠壁旁,回盲部5例,升结肠旁1例,降结肠旁3例,乙状结肠旁11例.结论 多层螺旋CT检查对病灶的诊断及鉴别诊断有重要价值.     

肠壁脂肪晕征分析

目的：评价非炎症性肠疾病肠壁“脂肪晕”征的表现与发病率。方法：回顾分析了100例怀疑肾结石而行腹部CT检查的患者。重点观察了升结肠、横结肠、降结肠、乙状结肠、直肠和末端回肠（大约30cm）的“脂肪晕”征。测量脂肪的密度、肠壁的厚度和患者的体重。结果：发现“脂肪晕”征21例（21％）。并发肾结石6例（29％）。“脂肪晕”征的CT值在-10至-68Hu之间。分布以升结肠、横结肠、降结肠多见。16人体重〉90kg。结论：没有炎症性肠疾病时，出现“脂肪晕”征代表肥胖症或正常表现。     

多层螺旋CT在肠扭转诊断中的应用价值

目的探讨多层螺旋CT(MSCT)对肠扭转诊断价值。方法回顾性分析11例肠扭转患者的CT检查资料和临床资料。结果 CT平扫显示肠管不同程度扩张、胀气,内见长短不一的液气平面影,肠壁和肠系膜增厚,密度减低,增强扫描病变肠段强化减弱。9例小肠扭转患者中,3例可见"U"形征,8例可见"漩涡征";4例见"鸟喙征";3例见"靶环征";2例MPR图像显示肠系膜血管扭曲,3例伴有腹腔积液。2例乙状结肠扭转患者均可见"鸟喙征",其中1例可见"S"征,另1例可见"U"形征。结论肠扭转CT表现有一定特征性,MSCT分辨率高,扫描速度快,并可多方位、多角度观察,对肠扭转的诊断有重要价值。     

一期手术治疗左半结肠癌并发急性肠梗阻

一、临床资料我院自1984年7月~1991年5月共收治结肠癌并发急性肠便阻患者36例,对其中21例左半结肠癌并发急性肠梗阻病人行一期肠切除吻合术.21例中男16例,女5例,年龄在35岁~72岁之间,平均52岁.发病时间lO~46小时,平均21小时.癌肿位于结肠脾曲3例,降结肠6例,均行左半结肠切除横结肠乙状结肠对端吻合术.位于乙状结肠者12例行超过肿瘤边缘6cm 以上乙状结肠切除,降结肠直肠对端吻合术.全部病人术后均得到病     

14例乙状结肠扭转多层螺旋CT诊断临床观察

[背景]探讨多层螺旋CT(MSCT)在乙状结肠扭转(SV)诊断中的临床意义.[病例报告]回顾性分析经外科手术证实的14例SV患者的临床资料,总结SV的MSCT特征.14例中手术复位治疗12例,2例外科手术中发现扭转的结肠缺血、坏死,进一步给行坏死肠段切除及腹壁造瘘术;所有患者术后恢复良好.MSCT检查结果均可见不同程度的结肠扩张、积气及气-液平面表现,扩张的乙状结肠肠壁菲薄,无法判断肠壁强化程度;均有鸟嘴征表现,5例有漩涡征表现,其中4例伴有少量腹腔或盆腔积液,外科手术证实为血性积液.[讨论]SV在MSCT检查中主要表现为结肠严重扩张、积气,鸟嘴征及漩涡征,亦表现为气-液平面或腹腔、盆腔积液.MSCT检查对SV的诊断具有临床意义.     

肠系膜脂膜炎多层螺旋CT诊断价值

目的 探讨肠系膜脂膜炎多层螺旋CT的诊断价值.方法 总结21例经临床及影像诊断证实的肠系膜脂膜炎的多层螺旋CT影像资料,其中手术证实2例,依据CT诊断标准诊断19例.采用CT平扫9例,平扫及增强12例.1例行MRI平扫及增强扫描.结果 21例病例中,12例发病部位起自小肠系膜根部,其余9例病变位于小肠系膜中上部.表现为肠系膜“脂肪晕环”征16例;“假包膜征”7例;肠系膜多发结节2例;7例表现为肠系膜血管周围局限或广泛的云絮状密度增高影;2例出现肠袢移位,无肠管受浸润病例;2例病变内可见小结节状钙化.结论 肠系膜脂膜炎无特征性临床表现.多层螺旋CT检查有助于肠系膜脂膜炎的诊断.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.