颅内≤5 mm动脉瘤破裂的危险因素分析

目的 探讨颅内小动脉瘤破裂的危险因素,为颅内未破裂小动脉瘤干预与否提供依据.方法 收集2010-2013年接受介入治疗、有详细影像资料和临床资料的单发性颅内小动脉瘤(≤5 mm)患者180例,其中破裂出血149例,未破裂31例.比较两组患者动脉瘤形态学参数之入射角、动脉瘤瘤体高度与瘤颈长度之比值(AR)、瘤体最大瘤深与近端载瘤动脉直径之比值(SR)、动脉瘤形状、位置和子囊,以及临床危险因素之年龄、性别、高血压、蛛网膜下腔出血史.采用单因素两独立样本t检验(或秩和检验)和卡方检验,以及多变量Logistic回归分析确定两组差异的显著性.结果 单因素分析显示破裂的小动脉瘤多位于前交通动脉(OR=0.166,P=0.023)及基底动脉末端(OR-0.006,P＜0.001),表明前交通部位与基底动脉末端的动脉瘤更易破裂.180例颅内小动脉瘤患者中破裂组与未破裂组动脉瘤部位、子囊、AR值(1.76±0.72对1.35±0.48)、SR值(1.90±0.81对1.31±0.67)、入射夹角(123.9°±23.21°对95.96°±20.2°)均存在明显的统计学差异(P＜0.05),而两组动脉瘤形态、动脉瘤最大直径以及临床危险因素中年龄、性别、高血压、蛛网膜下腔出血史均无统计学意义(P＞0.05).多变量Logistic回归分析显示动脉瘤部位(OR=1.347,P=0.002)、入射夹角(OR=1.057,P＜0.001)、SR值(OR=2.726,P=0.047)为颅内小动脉瘤破裂的独立危险因素.结论 前交通动脉和基底动脉末端部位、SR值＞1.90±0.81、入射角度＞ 123.9°±23.21°为颅内≤5 mm动脉瘤破裂的独立危险因素,可以作为颅内未破裂小动脉瘤干预与否的参考依据.     

动态容积CT在未破裂颅内动脉瘤随访中的应用价值

目的 探讨动态容积CT分析未破裂颅内动脉瘤(UIA)体积增长的危险因素。方法 选取114例共128个UIA患者的临床资料,包括性别、年龄、高血压、高血脂、糖尿病、脑卒中史,观察体积增长组及未增长组UIA的形态、有无子囊、位置、平均CTA随访次数,测量瘤体直径、瘤体高度、瘤体宽度、瘤颈宽度、瘤体最大层面面积、体积、动脉角度、血管角度、流入角度、平均载瘤动脉直径、瘤体高度/瘤颈宽度(AR)、瘤体直径/平均载瘤动脉直径(SR)。分析两组数据有无统计学差异。结果 经多因素Logistic回归分析后,体积≥0. 04ml、血管角度、流入角度是UIA体积增长的危险因素。结论 动态容积CT对于分析UIA体积增长的危险因素具有较高的应用价值。     

基于容积CT数字减影血管成像对颈内虹吸部动脉瘤破裂风险的研究北大核心CSCD

目的:比较破裂与未破裂虹吸部动脉瘤的形态学特征,为未破裂动脉瘤的风险评估提供参考依据。方法:回顾性分析经容积CT数字减影血管造影(VCTDSA)检查后被诊断为虹吸部动脉瘤的患者151例,其中未破裂组104例(共117个动脉瘤),破裂组47例(共49个动脉瘤),比较破裂组与未破裂组动脉瘤的形状、夹角等共21个指标,对上述指标行单因素分析,然后使用ROC曲线判断指标的灵敏度、特异度以确定最大临界值,最后用多因素logistic回归分析。结果:单因素分析中未破裂组与破裂组虹吸部动脉瘤在形状、部位、宽、高、瘤颈、大小、子母角、倾角、流入角、AR(瘤体长径/瘤颈宽)、SR(最大瘤径/载瘤动脉平均直径)、S1/S2(面积比)、最大径、瘤宽/瘤颈、年龄、多发上差异具有统计学意义。多因素分析显示瘤大小(OR=12.607,95%CI=4.400~36.124,P<0.001)、倾角(OR=4.062,95%CI=1.570~10.513,P=0.004)、是否为多发动脉瘤(OR=4.274,95%CI=1.620~11.272,P=0.003)为虹吸部动脉瘤破裂的独立危险因素。结论:颈内动脉虹吸部动脉瘤的瘤大小、倾角、是否为多发是形态学预测破裂的危险因素,其用于预测动脉瘤破裂的风险具有一定意义。     

4D-CT血管成像在≤5 mm前交通动脉瘤评估破裂风险中的应用研究

目的 探讨≤5 mm前交通动脉瘤破裂出血的相关危险因素.方法 回顾性分析47例≤5 mm前交通动脉瘤患者资料,按破裂与否分成2组,比较2组4D-CTT血管成像(CTA)图像测量的参数差异,包括动脉瘤的形状、子瘤或瘤壁针尖状小突起、单发或多发、瘤体长径、瘤颈宽度、尺寸比(SR)、高宽比(AR)、流动角、动脉瘤角、载瘤动脉...     

64层3D-CTA与3D-DSA对颅内动脉瘤评价的对比研究

目的 对比评价64层螺旋CT三维血管造影(3D-CTA)与三维数字减影血管造影(3D-DSA)对颅内动脉瘤的诊断价值.方法 28例临床怀疑颅内动脉瘤的患者均行64层螺旋CT血管造影和DSA,CT三维后处理主要包括容积重建(VR)及最大密度投影(MIP).常规二维DSA检查后,对可疑病变血管行旋转DSA检查,应用三维工作软件行3D后处理,比较3D-CTA与3D-DSA对动脉瘤显示的价值.结果 28例病例中22例CTA和DSA均显示动脉瘤并经手术或栓塞证实,其中1例CTA和DSA显示单个动脉瘤,手术证实为2个动脉瘤,1例CTA显示假阳性.3D-CTA与3D-DSA均能清楚显示动脉瘤形状、瘤径指向、瘤体直径、瘤颈、载瘤动脉、瘤体穿动脉情况,两者无明显差异.结论 64层3D-CTA在颅内动脉瘤诊断及细节显示上与3D-DSA无明显差异,一定程度上应能替代血管造影,指导临床治疗.     

三维CT血管造影与平板DSA对颅内动脉瘤诊断价值的对比分析

目的 对比分析多层螺旋CT三维血管造影(3D-CTA)与平板DSA对颅内动脉瘤的诊断价值.方法 对44例自发性蛛网膜下腔出血(SAH)患者同时行3D-CTA及平板DSA(包括2D-DSA、3D-DSA)检查,评价不同检查方法对动脉瘤的诊断效能、3D-CTA容积再现(VR)与3D-DSA容积再现(VR)对共同检出的动脉瘤之瘤体长径差异、瘤颈及载瘤动脉清晰度.结果 44例自发性SAH患者经外科手术或血管内介入证实36例为动脉瘤患者,共46个动脉瘤(其中26例单发,10例多发).3D-CTA共检出40例48个动脉瘤(灵敏度83.33%,特异度75%,阳性预测值75%,阴性预测值66.67%).2D-DSA检出38例患者中44个动脉瘤(灵敏度77.78%,特异度75%,阳性预测值73.68%,阴性预测值75%).3D-DSA最大密度投影(MIP)检出34例动脉瘤患者共44个动脉瘤(灵敏度94.44%.特异度100%,阳性预测值100%,阴性预测值100%).3D-DSA(VR)检出36例动脉瘤患者共46个动脉瘤,无漏诊及误诊.就颅内动脉瘤的检出率方面,3D-CTA与2D-DSA、3D-DSA(MIP)的检出率差异无统计学意义(P>0.05),但3D-CTA(VR)与3D-DSA(VR)的检出率差异有统计学意义(P<0.05).无论是≥3 mm的动脉瘤还是<3 mm的动脉瘤,3D-CTA(VR)与3D-DSA(VR)对瘤体长径的测量差异均无统计学意义(P>0.1).在瘤颈及载瘤动脉清晰度显示方面,3D-CTA(VR)与2D-DSA和3D-DSA(VR)差异均有统计学意义(P<0.05),但3D-CTA(VR)与3D-DSA(MIP)差异无统计学意义(P>0.05).结论 3D-CTA对瘤体长径≥3 mm的颅内动脉瘤有很高的诊断效能,可作为一种微创的常规筛查方法,但对长径<3 mm的颅内动脉瘤有较高的漏诊及误诊率,对其未发现颅内动脉瘤的SSAH患者应进一步行3D-DSA检查.     

多层螺旋CT血管造影在诊断颅内动脉瘤中的应用进展

颅内动脉瘤是神经外科常见病，破裂出血死亡率较高，需要早期诊断与治疗。多层螺旋CT血管造影操作简便，快速，经济，无创，准确性、敏感性高，能够准确地显示动脉瘤的位置、形状、大小，瘤颈与颅底骨结构、载瘤动脉的关系等，可作为临床诊断动脉瘤首选方法和术前确定手术方案重要参考。     

CTA对颅内动脉瘤的诊断价值

目的 :探讨16层CTA对颅内动脉瘤的诊断价值。方法:CTA诊断30例颅内动脉瘤,所得原始CT数据传至Philips工作站后运用MPR、CPR、MIP、VR等技术行血管成像;30例颅内动脉瘤均行手术治疗,术后对照CTA检查的准确性。结果:30例患者手术发现动脉瘤36个,CTA发现35个,诊断符合率97.22%(35/36),未能显示的1个位于右大脑中动脉分支末梢,瘤径3 mm;CTA所示动脉瘤的位置、大小、形态、瘤顶指向、瘤颈宽窄、载瘤动脉、瘤体与周围结构关系,与术中所见一致。结论:16层CTA对Willis环周围瘤径3.0 mm以上的动脉瘤显示清晰,是一种准确、快速、价廉、无创的诊断颅内动脉瘤方法 ,可作为脑动脉瘤筛选及动脉瘤破裂致急性出血的首选检查方法。     

应用4D-FLOW MRI血流成像评价颅内囊状动脉瘤血流动力学状态特征

目的 应用四维血流磁共振成像(4D-FLOW MRI)技术,研究颅内囊状动脉瘤及瘤颈周围载瘤动脉内血流动力学变化特征。方法 经头颅CT血管造影(CTA)或磁共振血管造影(MRA)诊断为颅内囊状动脉瘤患者68例;应用4D-FLOW技术扫描并重建后进行血流动力学分析。在载瘤动脉的囊状动脉瘤入口截面处、囊状动脉瘤沿血流方向最大截面处、囊状动脉瘤出口截面处以及对侧动脉的对称位置分别手动勾画血管边缘轮廓,自动获取血流动力学参数。采用配对t检验比较载瘤动脉与对侧动脉之间的血流动力学参数。根据囊状动脉瘤最大径和尺寸比(SR)分组,采用独立样本t检验分析不同分组载瘤动脉血流动力学参数的差异。结果 载瘤动脉与对侧动脉比较,颅内囊状动脉瘤入口截面最大壁剪切应力(WSS)、平均WSS、最大轴向WSS-最大周向WSS小于对侧对称截面;囊状动脉瘤沿血流方向最大截面处最大WSS、平均WSS、平均轴向WSS、平均轴向WSS-平均周向WSS在载瘤动脉中较小,载瘤动脉中的最大能量损失和平均能量损失显著高于对侧动脉,上述差异均具有统计学意义(P<0.05)。在载瘤动脉中最大径>5 mm组的囊状动脉瘤入口截面最...     

CTA与DSA诊断颅内动脉瘤的对比研究

目的通过与DSA对比,评价三维CT血管造影在颅内动脉瘤诊断中的价值。方法对30例因蛛网膜下腔出血高度怀疑动脉瘤破裂的病人行CTA检查,同期行DSA检查及可行的血管内栓塞治疗。比较CTA与DSA检出动脉瘤的敏感性、特异性和准确性以及在显示动脉瘤瘤颈和载瘤动脉关系上的优劣。结果CTA检出动脉瘤26个,对动脉瘤的敏感性为95.5%,特异性为87.5%,准确性为93.3%,与DSA比较无显著差异。CTA对动脉瘤细节及瘤颈的显示明显优于DSA。结论CTA能无创有效的诊断颅内动脉瘤,所提供的诊断信息对治疗方案的制订具有极大的帮助,CTA还特别适用于急症病人的动脉瘤筛查。     

Geometric Parameter Analysis of Ruptured and Unruptured Aneurysms in Patients with Symmetric Bilateral Intracranial Aneurysms: A Multicenter CT Angiography Study

BACKGROUND AND PURPOSE:Previous studies of geometric and morphologic parameters of intracranial aneurysms have been conducted to determine rupture risk, which remains incompletely defined due to patient-specific risk factors, such as sex, hypertension, and age. To this end, we compared characteristics of ruptured and unruptured aneurysms in the same patients with symmetric bilateral intracranial aneurysms.MATERIALS AND METHODS:Between January 2008 and March 2014, 2361 patients with 2674 aneurysms were diagnosed by CT angiography or surgical findings at 4 medical centers. Geometric and morphologic parameters examined for symmetric bilateral intracranial aneurysms comprised aneurysm wall regularity, size, neck width, aspect ratio, size ratio, neck-to-parent artery ratio, and area ratio. Univariate and multivariate statistical analyses were performed to determine independent risk factors for rupture.RESULTS:Sixty-three patients (48 women, 15 men; mean age, 62.5 ± 9.8 years) with symmetric bilateral aneurysms were eligible for the study and were included. The most frequent aneurysm location was the posterior communicating artery. Univariate analysis disclosed that aneurysm size, aspect ratio, size ratio, area ratio, and irregular wall differed between patients with ruptured and unruptured aneurysms. Multivariate analysis indicated that aspect ratio of ≥1.6 (adjusted OR, 9.521; 95% CI, 2.182–41.535), area ratio of ≥1.5 (adjusted OR, 4.089; 95% CI, 1.247–13.406), and irregular shape (adjusted OR, 10.443; 95% CI 3.394–32.135) were significant predictive factors for aneurysm rupture after adjustment for aneurysm size.CONCLUSIONS:An aspect ratio of ≥1.6, area ratio of ≥1.5, and irregular wall are associated with aneurysm rupture independent of aneurysm size and patient characteristics. These characteristics alone can help in distinguishing ruptured bilateral intracranial aneurysms from unruptured ones.

Unruptured intracranial aneurysms are common lesions with a prevalence of 3%–7%.^1,2 Aneurysm rupture is the primary cause of subarachnoid hemorrhage, leading to high morbidity and mortality. Meanwhile, prophylactic treatment of unruptured intracranial aneurysms is also associated with risks.^3,4 Therefore, identification of the risk factors for aneurysm rupture is essential for both risk assessment and treatment.Previous research on geometric parameters, including aspect ratio (AR), size ratio (SR), and aneurysm flow angles, has shown their association with aneurysm rupture.^5–7 However, conclusions are confounded by patient-specific characteristics, such as hypertension, age, and history of subarachnoid hemorrhage from another aneurysm which, along with geographic region, have been identified as risk factors for aneurysm rupture.^8–10 Hence, aneurysm-related factors need to be analyzed by comparing the aneurysm characteristics of ruptured and unruptured aneurysms in the same individual to identify risk factors in a case-control design. We conducted a multicenter, retrospective cohort study of intracranial aneurysms in the Chinese population. The objectives of the article were to elucidate the morphologic and geometric parameters that discriminate intracranial aneurysm rupture status in the same patient with symmetric bilateral intracranial aneurysms.     

CT of abdominal aortic aneurysms--aneurysmal size and thickness of intra-aneurysmal thrombus as risk factors of rupture

In order to seek for the factors to suggest a risk of rupture of abdominal aortic aneurysms (AAA), we measured the largest diameter of AAA and the thickness of intra-luminal thrombus on CT in 72 patients. The mean aneurysmal size was 64 mm in diameter in 9 patients with ruptured aneurysm and 61 mm in diameter in 63 patients with non-ruptured aneurysm respectively (p less than 0.90). The rupture of AAA was seen in 3 of 30 patients with AAA of the small size (less than 50 mm in diameter), in 3 of 16 patients with AAA of the intermediate size (51-66 mm in diameter) and in 3 of 26 patients with AAA of the large size (more than 70 mm in diameter), respectively. The mean intra-luminal thrombus was 9 mm in 9 patients with ruptured aneurysm and 19 mm in thickness in 63 patients with non-ruptured aneurysm respectively (p = 0.05). We concluded from the above results that the aneurysmal size was not important, but the thickness of intra-luminal thrombus was useful for suggestion of a risk of rupture of AAA.     

多层螺旋CT 三维血管造影容积重建成像在颅内动脉瘤中的诊断价值

目的探讨多层面螺旋CT三维血管造影(MS 3D-CTA)容积重建(VR)技术在颅内动脉瘤中的诊断价值.方法对109例临床怀疑颅内动脉瘤的病人行MS 3D-CTA和DSA检查.使用GE Lightspeed pro 16层螺旋CT扫描仪获得原始图像,所有病例均采用VR技术对图像进行三维重建,20例同时有最大密度投影(MIP)辅助检查.VR和MIP后处理图像以及DSA图像由3位放射科医生用双盲法进行分析.结果DSA和手术证实83例共94个动脉瘤,其中单发74例,多发9例(7例2个动脉瘤,2例3个动脉瘤).VR图像上所测动脉瘤大小为1.3～32 mm,与DSA比较无显著性差异(t=1.548,P＞0.05).VR对颅内动脉瘤的敏感度为96.8%,特异度为92.9%,准确度为95.9%,阳性预测值为97.8%,阴性预测值为89.7%;DSA敏感度为97.9%,特异度为96.3%,准确度为97.5%,阳性预测值为98.9%,阴性预测值为92.9%.94个动脉瘤中,89个(94.7%)动脉瘤在VR图像上能清晰显示瘤体、瘤颈与载瘤动脉的三维空间关系,DSA为57个(60.6%).结论MS 3D-CTA VR的敏感度、特异度和准确度均较高,是一种快捷、经济和有效的检查技术.     

Assessing the Risk of Intracranial Aneurysm Rupture Using Morphological and Hemodynamic Biomarkers Evaluated from Magnetic Resonance Fluid Dynamics and Computational Fluid Dynamics

Purpose:Evaluate in vivo hemodynamic and morphological biomarkers of intracranial aneurysms, using magnetic resonance fluid dynamics (MRFD) and MR-based patient specific computational fluid dynamics (CFD) in order to assess the risk of rupture.Methods:Forty-eight intracranial aneurysms (10 ruptured, 38 unruptured) were scrutinized for six morphological and 10 hemodynamic biomarkers. Morphological biomarkers were calculated based on 3D time-of-flight magnetic resonance angiography (3D TOF MRA) in MRFD analysis. Hemodynamic biomarkers were assessed using both MRFD and CFD analyses. MRFD was performed using 3D TOF MRA and 3D cine phase-contrast magnetic resonance imaging (3D cine PC MRI). CFD was performed utilizing patient specific inflow–outflow boundary conditions derived from 3D cine PC MRI. Univariate analysis was carried out to identify statistically significant biomarkers for aneurysm rupture and receiver operating characteristic (ROC) analysis was performed for the significant biomarkers. Binary logistic regression was performed to identify independent predictive biomarkers.Results:Morphological biomarker analysis revealed that aneurysm size [P = 0.021], volume [P = 0.035] and size ratio [P = 0.039] were statistically significantly different between the two groups. In hemodynamic biomarker analysis, MRFD results indicated that ruptured aneurysms had higher oscillatory shear index (OSI) [OSI.max, P = 0.037] and higher relative residence time (RRT) [RRT.ave, P = 0.035] compared with unruptured aneurysms. Correspondingly CFD analysis demonstrated significant differences for both average and maximum OSI [OSI.ave, P = 0.008; OSI.max, P = 0.01] and maximum RRT [RRT.max, P = 0.045]. ROC analysis revealed AUC values greater than 0.7 for all significant biomarkers. Aneurysm volume [AUC, 0.718; 95% CI, 0.491–0.946] and average OSI obtained from CFD [AUC, 0.774; 95% CI, 0.586–0.961] were retained in the respective logistic regression models.Conclusion:Both morphological and hemodynamic biomarkers have significant influence on intracranial aneurysm rupture. Aneurysm size, volume, size ratio, OSI and RRT could be potential biomarkers to assess aneurysm rupture risk.     

Abciximab for thrombolysis during intracranial aneurysm coiling

Introduction  Thrombotic events are a common and severe complication of endovascular aneurysm treatment with significant impact on patients’ outcome. This study evaluates risk factors for thrombus formation and assesses the efficacy and safety of abciximab for clot dissolution. Materials and methods  All patients treated with abciximab during (41 patients) or shortly after (22 patients) intracranial aneurysm coil embolisation were retrieved from the institutional database (2000 to 2007, 1,250 patients). Sixty-three patients (mean age, 55.3 years, ±12.8) had received either intra-arterial or intravenous abciximab. Risk factors for clot formation were assessed and the angiographic and clinical outcome evaluated. Results  No aneurysm rupture occurred during or after abciximab application. The intra-procedural rate of total recanalisation was 68.3%. Thromboembolic complications were frequently found in aneurysms of the Acom complex and of the basilar artery, whilst internal carotid artery aneurysms were underrepresented. Two patients died of treatment-related intracranial haemorrhages into preexisting cerebral infarcts. Two patients developed a symptomatic groin haematoma. Conclusions  Abciximab is efficacious and safe for thrombolysis during and after endovascular intracranial aneurysm treatment in the absence of preexisting ischaemic stroke.     

CT of aortic aneurysms: the distinction between mural and thrombus calcification

Aortic calcification, either mural or thrombus, is a common finding in patients with abdominal aortic aneurysms. Differentiating between the two sites of calcification is necessary in order to avoid confusing simple thrombus calcification with displaced calcified intima in aortic dissection. The CT scans of 145 cases of abdominal aortic aneurysm and seven cases of abdominal aortic aneurysm with dissection were analyzed with respect to the location of the calcification: mural only or mural and thrombus. Mural calcification was seen in all 152 patients with aneurysms whereas thrombus calcification was identified in only 33 (24%) of the 136 patients with thrombus. Displaced intimal calcification caused by aortic dissection can either appear similar to or, at times, be indistinguishable from thrombus calcification. Thrombus calcification was present in four (57%) of the seven patients with abdominal aortic aneurysms and dissection. To avoid the possibility of a false-positive diagnosis of aortic dissection in patients with abdominal aortic aneurysm, other signs of aortic dissection should be sought such as separation of the true and false lumina by an intimal flap.     

多层螺旋CT三维血管成像在颅内动脉瘤夹闭术后随访中的初步应用

目的探讨多层螺旋CT三维血管成像（MS3D-CTA）在颅内动脉瘤夹闭术后随访中的应用价值。方法回顾性分析16例颅内动脉瘤患者夹闭术前后的MS3D-CTA资料。用16层螺旋CT扫描仪获得原始图像，然后采用容积重组（VR）、薄层最大密度投影（MIP）和多平面重组（MPR）技术对图像进行后处理。结果16例颅内动脉瘤夹闭术后复查共发现17个动脉瘤夹，其中后交通动脉瘤6例，前交通动脉瘤5例，大脑中动脉瘤4例，胼周动脉瘤1例2个动脉瘤夹。MS 3D-CTA检查未见异常7例，动脉瘤残留2例，载瘤动脉局限性狭窄4例，伴有血管痉挛3例，所有患者均未见载瘤动脉闭塞及动脉瘤夹滑脱移位征象。VR上12例清晰显示瘤夹及载瘤动脉的三维空间关系，3例较清晰显示，1例胼周动脉瘤使用2个瘤夹者线束硬化性伪影明显而显示较差；动脉瘤夹的形态及大小在薄层MIP与MPR上均能准确显示，但瘤夹与载瘤动脉的三维空间感较差。结论MS3D-CTA是颅内动脉瘤夹闭术后快捷、安全和有效的随访检查手段，VR与薄层MIP、MPR结合可更好地显示颅内动脉瘤夹闭术后改变。     

大脑脚脚间角对低颅压综合征患者的临床价值

目的:探讨MR I大脑脚脚间角测量在诊断低颅压综合征中的临床价值.方法:搜集经临床诊断的43例低颅压综合征患者及性别、年龄相匹配的43例健康志愿者的临床和MR I资料.对比分析2组患者的主要MR I表现(包括有无硬脑膜增厚及/或强化、脑下垂、静脉窦扩张、硬膜下积液等)及大脑脚脚间角(在经乳头体层面的横轴面T2 WI上由...     

CTA与MRA诊断动脉瘤及评估动脉瘤破裂风险的比较

 目的 比较CT血管造影术(CT angiography,CTA)与磁共振血管造影(magnetic resonance angiography,MRA)诊断动脉瘤与动脉瘤破裂的风险评估价值。方法 48例高度怀疑为颅内动脉瘤患者随机分为两组,每组24例,记为Ⅰ组和Ⅱ组,其中Ⅰ组行CTA+DSA检查,Ⅱ组行MRA+DSA检查。比较CTA及MRA对颅内动脉瘤的诊断灵敏度、诊断特异性、阳性预测值、阴性预测值及准确率。比较CTA及MRA对5 mm以上动脉瘤的诊断价值。结果 MRA诊断颅内动脉瘤的诊断灵敏度、诊断特异性、阳性预测值、阴性预测值、准确率较CTA稍低,但二者差异无统计学意义。CTA与三维增强MR血管成像(3D CE-MRA)对5 mm以上动脉瘤的诊断能力相当,但与三维时间飞跃法MR血管成像(3D TOF MRA)相比,CTA与CE-MRA的诊断灵敏度、诊断特异性、阳性预测值、阴性预测值、准确率明显较高,差异有统计学意义(P<0.05);CTA能更清楚地显示瘤颈。结论 CTA和MRA可作为诊断动脉瘤与动脉瘤破裂的风险评估的首要手段,CTA诊断的准确率及三维形态高于MRA。