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生物羊膜移植在青光眼小梁切除术中的疗效观察 总被引:1,自引:0,他引:1
目的观察羊膜移植小梁切除术治疗青光眼的临床疗效。方法对23例29只眼原发性青光眼进行常规小梁切除术,并在巩膜瓣下植入羊膜,观察术后眼压、视野、视力等情况,术前术后对比,并随访6~12个月,观察术后疗效。结果术后眼压均有降低,都形成较明显的弥散滤过泡,随访期间,眼压、视力、视野维持良好,功能性滤过泡长期存在,未出现不良反应。结论小梁切除联合羊膜移植术能有效地预防术后组织瘢痕的形成,促进青光眼功能性滤泡的维持,减少术后浅前房的发生,有效地控制了眼压。 相似文献
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李小珩 《中华临床医药杂志(北京)》2004,5(10):54-54
难治性青光眼为一组药物难以控制眼压而常规手术治疗预后差的青光眼。近2年来,我科共收治难治性青光眼总15例,均行羊膜移植联合小梁切除术,现将结果报告如下。 相似文献
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目的探讨干燥羊膜移植联合小梁切除术治疗难治性青光眼的有效性和安全性。方法采用国产干燥羊膜移植联合复合式小梁切除术治疗难治陛青光眼32例(39眼),术后随访6~24个月,检查记录术后视力、滤过泡、前房深度、眼压及术后并发症等情况。结果随访期间眼压由术前(41.3±5.1)mmHg降至术后(17.2±5.3)mmHg,比术前降低59.9%,P〈0.001。手术总成功率为93.4%,保持功能性滤过泡34眼(87.2%),术后视力提高2行以上者为27眼(69.2%),并发症主要包括浅前房(5眼)、低眼压(9眼)和前房积血(4眼)。结论羊膜移植联合复合式小梁切除术可减少滤过道疤痕的形成,提高手术的成功率,是治疗难治性青光眼安全有效的方法之一。 相似文献
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Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma. 相似文献
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Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma. 相似文献
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Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma. 相似文献
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Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma. 相似文献
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Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma. 相似文献
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Objective To explore the effect and security of dry amniotic membrane transplantation com-bined with trabeculectomy on refractory glaucoma. Methods Dry amniotic membrane transplantation combined with trabeculectomy was performed on 32 cases (39 eyes) with refractory glaucoma. All the patients were followed-up for 6-24 months. The acuity of visual, filtering bleb, anterior chamber depth, IOP and the complications of operation were studied. Results The IOP was descended 59.9 % (P<0.001) from (41.3±5.1)mmHg pre-operation to(17.2±5.3) mmHg post-operation. The total success rate was 93.4 %. After operation, 34 eyes (87.2 %) were kept functional filtering bleb. 27 eyes (69.2 %) had improved visual acuity. The complications included shallow anterior chamber (5 eyes) and early postoperative hypotony (9 eyes). Conclusions Amniotie membrane transplantation combined with trabeculectomy for refractory glaucoma can effectively inhibit the sear formation, decrease the IOP and increase the success rate considerably. The method is safe and effective in the treatment of refractory glaucoma. 相似文献
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目的探讨羊腰移植联合小梁切除治疗难治性青光眼的疗效。方法对24例25眼难治性青光眼进行羊膜移植联合小梁切除术后对眼压、滤泡、前房、视力进行3~7个月观察随访。结果术后3个月93.8%的眼压控制在8~20mmHg、6个月85.8%的眼压控制在8~20mmHg,5例5眼需局部加用降眼压药物。术后3个月23眼形成功能性滤泡,有效率为92%,6个月21眼形成功能性滤泡,有效率为91%,视力均有不同程度的改善,前房稳定。结论羊膜移植能有效防止滤过泡疤痕纤维化,是治疗难治性青光眼的简单、安全、有效方法。 相似文献
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目的 研究羊膜应用于小梁切除术的临床疗效。方法 将49例(52只患眼)采用巩膜瓣下羊膜植入术,术后观察视力、眼压、滤泡及并发症:术后随访(11.6±7.1)个月。结果 视力提高15只患眼(34.51%),功能性滤泡形成50只患眼(96.15%),46只患眼(92.00%)眼压8.7~21.87mmHg,平均(16.5±5.66)mmHg,6只患眼(11.53%)需联合1种降眼压药物控制眼压,眼压基本稳定。结论 羊膜应用于小梁切除术可有效地防止滤过泡的瘢痕组织形成,并能有效的长期保留功能性滤泡。 相似文献
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目的研究羊膜应用于小梁切除术的临床疗效。方法将49例(52只眼)采用巩膜瓣下羊膜植入术,术后观察视力、眼压、滤泡及并发症。术后随访(11.6±7.1)个月。结果视力提高15只眼(34.51%),功能性滤泡形成50只眼(96.15%),46只眼(92.00%)眼压8.7~21.87 mm Hg,平均(16.5±5.66)mm Hg,6只眼(11.53%)需联合1种降眼压药物控制眼压,眼压基本稳定。结论羊膜应用于小梁切除术可有效地防止滤过泡的瘢痕组织形成,并能有效的长期保留功能性滤泡。 相似文献
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目的探讨小梁切除术联合羊膜植入治疗闭角型青光眼的临床疗效。方法对48例(55眼)闭角型青光眼患者行小梁切除术,术中巩膜瓣下植入保存羊膜,术后观察患者视力、眼压、前房及滤过泡情况,术后随访6~18个月。结果眼压由术前的(32.43±5.76)mmHg降至术后的(16.63±4.07)mmHg(P〈0.01),功能性滤过泡形成率为89%,无排斥反应和严重并发症。结论小梁切除联合羊膜植入可减少滤过口瘢痕的形成,提高手术成功率。 相似文献
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目的:探讨小梁切除术联合可调整缝线治疗闭角型青光眼对患者眼表功能的影响。方法98例(134眼)按照数字表法随机分为两组,对照组49例(66眼),采用小梁切除术治疗,观察组49例(68眼)采用小梁切除术联合可调整缝线治疗。观察两组患者术前及术后3个月眼压变化情况、视力恢复情况及浅前房的发生情况。并对患者术后1d、3d、1个月和3个月的眼表功能进行评分。结果两组患者术后3个月眼压均有明显降低(t=3.921、5.746,均P<0.01),并且观察组较对照组降低更明显(t=2.680,P<0.05)。两组患者术后3个月视力均有明显提高(t=2.460、2.976,均P<0.05),并且观察组较对照组提高更明显(t=2.062,P<0.05)。对照组术后浅前房发生率为12.1%(8/66);观察组术后浅前房发生率为2.9%(2/68);观察组浅前房发生率明显少于对照组(χ2=7.98,P<0.01)。术后两组患者的眼表功能评分均逐渐降低,观察组患者术后1 d、3 d、1个月和3个月眼表功能评分均低于对照组( t=2.191、2.680、3.172、3.013,均P<0.05)。结论小梁切除术联合可调整缝线治疗闭角型青光眼可促进患者眼表功能的恢复。 相似文献
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目的探讨青光眼小梁切除术治疗各种类型青光眼,控制眼压及改善视力的疗效观察。探索一些提高手术成功率的方法。方法施行青光眼小梁切除术31例(35只眼)各种类型青光眼,术中使用抗代谢药物丝裂霉素C(MMC)抑制滤过区瘢痕形成,以获得功能性滤过泡和理想的眼压控制。随访1年。结果 31例(35只眼)除2例前房延缓形成,经保守治疗后前房恢复正常,大部分病例术后炎性反应轻微,有2例(3只眼)术后炎性反应较重,用阿托品散瞳,全身应用皮质类固醇,口服吲哚美辛(消炎痛)使炎症控制,术后眼压控制在12.22~20.55mmHg,全部形成功能性滤过泡。随访1年期间,均未发现前房消失或变浅和低眼压等并发症。结论青光眼小梁切除联合丝裂霉素C(MMC)治疗青光眼近、远期效果好,并发症少,成功率高。 相似文献
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目的探讨改良小梁切除术与小梁切除术治疗青光眼的术后疗效比较与分析。方法选取青光眼患者95例(95眼)随机分成观察组49例(49眼),对照组46例(46眼),分别行改良小梁术与小梁切除术。结果经统计学处理,术后早期眼压控制情况与前房形成情况无显著性差异(P>0.05),但术后远期眼压控制情况与功能性滤过泡形成情况比较有显著性差异(P<0.05)。结论改良小梁切除术较小梁切除术具有良好的远期眼压控制效果和形成良好的功能性滤过泡,减少了手术并发症的优点。 相似文献
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目的观察白内障超声乳化吸除人工晶体植入联合小梁切除术与白内障囊外摘除人工晶体植入联合小梁切除术治疗青光眼合并白内障的临床疗效。方法回顾分析患青光眼白内障在我院行超声乳化白内障吸除人工晶体植入联合小梁切除术(超乳三联术组)的患者74例(92眼),和行白内障囊外摘除人工晶体植入联合小梁切除术(囊外三联术组)的患者40例(52眼),记录手术前、后的视力和眼压,记录手术并发症和滤过泡情况。结果超乳三联术组术后平均眼压为(13.72±2.72)mm Hg,囊外三联术组术后平均眼压(12.92±5.35)mm Hg,较术前显著下降(P<0.01),且两组下降值差异无显著性(t=0.166,P>0.05)。超乳三联术组术后视力显著提高(χ2=18.254,P<0.01),囊外三联术组手术前后视力差异无显著性。术后3个月随访,眼压≥21mm Hg者,超乳三联术组2只眼,囊外三联术组4只眼,两组比较差异无显著性意义(P>0.05)。手术并发症超乳三联术组明显低于囊外三联术组,差异有极显著性意义(P<0.01)。两组术后均无严重并发症发生。结论超声乳化白内障吸除人工晶体植入联合小梁切除术,可安全有效治疗青光眼合并白内障,且效果优... 相似文献
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目的观察分析青光眼小梁切除术后低眼压性浅前房的发病病因及其防治方法,总结其处理效果及临床经验。方法选取我院2009年6月至2012年6月186例(236眼)青光眼行小梁切除术治疗的患者,对其术后并发症及处理的情况进行回顾性分析。结果 186例患者(236眼)中,术后发生低眼压性浅前房并发症有18例(18眼),占7.63%,采取保守治疗后痊愈有16例,治愈率为88.9%,余下2例疗效欠佳,后改为行切口修补术治疗,皆治愈出院,还有1例改为行前房重建术治疗,也治愈出院,随访半年,无再次并发低眼压性浅前房案例。结论低眼压性浅前房是青光眼小梁切除术后常见的并发症,应术后给予积极预防,一旦发现,应给予对症处理,可先采取保守治疗,疗效不理想可对酌情给予手术治疗,改善预后,具有重要的临床意义。 相似文献