Restoration with implants in patients with recessive dystrophic epidermolysis bullosa and patient satisfaction with the implant-supported superstructure

PURPOSE: The use of endosseous implants in the prosthetic restoration of edentulous patients with recessive dystrophic epidermolysis bullosa (RDEB) may provide improved outcomes when compared with traditional prosthetic methods. The aim of this study was to evaluate the feasibility of placing endosseous implants in patients with RDEB and to compare the treatment outcomes of fixed and removable implant-supported restorations in the edentulous maxilla or mandible with the main emphasis on patient response. MATERIALS AND METHODS: Six patients with RDEB were treated with implants. All patients were completely edentulous in either the maxilla or mandible and had marked oral involvement, with alterations in the soft and hard tissues in all cases. Three patients were treated with fixed, screw-retained implant-supported prostheses, and 3 were treated with removable implant-supported prostheses. Six months after prosthetic restoration, patients were given a questionnaire to assess their psychologic well-being and satisfaction with the implant-supported restoration marked on a visual analog scale. RESULTS: A total of 38 dental implants (21 maxillary, 17 mandibular) were placed in 6 patients. The implant success rate was 97.9%. The average follow-up from implant placement was 5.5 years (range, 1 to 9). The fixed and removable implant-supported prostheses were associated with improvements in comfort and retention, function, esthetics and appearance, taste, speech, and self-esteem. The level of satisfaction was slightly higher in patients with a fixed prosthesis. CONCLUSION: These findings suggest that endosseous implants can be successfully placed and provide support for prostheses in patients with RDEB. Patients with fixed prostheses and overdentures were satisfied with their implant-supported prostheses in the edentulous maxilla and mandible.     

功能性颌骨重建61例临床分析

目的:评价采用多种骨瓣进行功能性颌骨重建的临床效果。方法:61例颌骨缺损患者,首先应用多种骨瓣重建颌骨的连续性,然后植入骨结合种植体,利用种植义齿重建患者的咀嚼和发音功能。61例患者中,男39例,女22例,平均年龄48岁(20～61岁)。游离髂骨瓣32例,血管化腓骨瓣21例,单纯牵引成骨重建颌骨7例,其他骨瓣1例。共植入种植体247颗。种植固定义齿修复29例,种植体支持的活动义齿修复32例。结果:种植义齿修复完成后平均追踪49个月(6～114个月),种植体脱落6颗。1例患者在修复完成2年后因肿瘤复发死亡(含4颗种植体,不计入存活种植体)。至最后复查,共237颗种植体仍在行使功能,累计5年存活率为95.95%。结论:应用游离髂骨瓣、血管化腓骨瓣重建颌骨的连续性后,植入骨结合种植体,能够有效地重建患者的咀嚼、发音功能,近期效果满意。     

Steri-Oss种植体支持固定和可摘义齿修复牙列缺失患者的临床回顾研究

目的：研究十年观察期内用Steri-Oss种植体修复牙列缺失患者种植体生存率和影响因素。方法：自1995-2006年,共有57例无牙颌患者接受种植与修复治疗,共353颗Steri-Oss种植体。其中81颗种植体（22.95%）做固定修复,272颗种植体（77.05%）做可摘义齿修复,观察性别、种植体部位和修复类型对种植体成功率的影响。结果：其中有9例病人24颗种植体脱落,种植体成功率93.20%,女性病人的种植体生存率略低,但性别没有显著的差异（P〉0.05）。累计的种植体生存率上颌骨92.64%,略低于下颌骨93.68%,但统计学上的没有显著差异（P〉0.05）。种植体支持的固定修复的十年成功率是97.5%,种植体固位的可摘义齿成功率99.02%,累计的种植体生存率在可摘与固定义齿修复之间没有显著性差异（P〉0.05）。结论：确认了种植体支持无牙颌病人修复学中长期成功率。种植体固位的可摘全口义齿治疗方式在种植体生存率上和种植体支持的固定义齿的结果是相同的。     

The management of a completely edentulous patient using simultaneous maxillary and mandibular CAD/CAM-guided immediately loaded definitive implant-supported prostheses: a clinical report

Functional rehabilitation of a completely edentulous patient with removable prostheses is a clinical challenge. A patient with an edentulous maxilla and mandible received 6 endosseous implants in the maxilla and 5 implants in the mandible using CAD/CAM surgical templates. Definitive maxillary and mandibular implant-supported fixed complete dentures were connected immediately after implant placement using a CAD/CAM-guided implant surgical placement protocol.     

Implant-supported mandibular telescopic prostheses in oral cancer patients: an up to 9-year retrospective study

PURPOSE: The aim of this retrospective study was to present the results of implant-supported telescopic prostheses in the mandible after removal of malignant tumors. MATERIALS AND METHODS: Between 1991 and 2000, 24 patients with squamous cell carcinoma (16 irradiated, eight nonirradiated) underwent mandibular rehabilitation with implant-supported telescopic prostheses. A total of 111 dental implants were placed. Treatment complications were observed. The cumulative survival rates of the implants and prostheses were evaluated by lifetable analysis. RESULTS: Within a mean follow-up period of 30 months (1 to 108 months), only three implants failed. All other implants are still in function. Of 24 patients, 23 were satisfied with their implant-supported telescopic restorations. Soft tissue, implant, or prosthetic complications occurred very rarely. The cumulative implant survival rate was about 97% and the cumulative prosthesis survival rate was about 95% at 9 years. CONCLUSION: Implants and implant-supported telescopic maxillofacial prostheses can successfully remain in function over a long period. Increased implant and prosthetic complications should not be expected. Therefore, telescopic implant attachments seem to be very useful as a treatment option for prosthetic restoration of the mandible in tumor patients.     

口腔种植修复临床效果五年回顾研究

目的:评估柱状种植体应用5年的临床效果。方法:2001年2月至2005年12月植入柱状种植体共931枚,其中Pitt-easy种植体174枚,Frialit-2种植体148枚,Camlog种植体350枚,XiVE种植体176枚,Ankylos种植体45枚,I.M.Z种植体38枚。全部种植体均在2005年12月前完成上部结构修复,其中固定修复456例,活动修复8例,共计464例患者。平均追踪30个月(4-59月)。观察方法为X线检查和临床检查,采用Wheeler存留标准评估,纳入Kaplan-Meier存留曲线统计。结果:种植修复体完成时451例患者对修复效果满意,13例患者对修复体不满意,重做后10例表示满意,3例表示可以接受。随访中有34例患者共46枚种植体确诊为种植体周围炎。有明确记录的共24枚种植体脱落。5年随访累计修复体松动14件,修复体折断8件。据Wheeler存留标准统计5年存留率为95.2%。结论:种植修复患者的满意度高,本组种植体的5年存留率达到95.2%。     

牙列缺失患者种植体支持的固定和可摘义齿的回顾性研究

目的:研究十年观察期内种植体支持的固定和可摘义齿修复牙列缺失患者种植体的生存率和影响因素。方法:1995-2006年,227例患者(92例男性,135例女性)平均年龄63.7岁,在Charite’大学口腔颌面外科门诊接受种植和修复治疗。共1652颗种植体种植在牙列缺失上颌骨、下颌骨或双侧颌骨,支持76例(24.68%)固定义齿,232例(75.32%)可摘义齿。观察性别,种植体部位、修复方法对种植体生存率的影响。结果:其中有50例患者73颗种植体丧失,累计种植体生存率94.76%,本研究显示种植体生存率女性(93.93%)略低于男性(95.93%),但没有显著性差异。在上颌骨种植的种植体生存率(95.87%)略高于在下颌骨种植(94.53%),但统计学没有显著性意义。10年累计固定和可摘义齿的种植体生存率分别是98.02%和93.55%,两种修复方法差异有显著性。结论:确认了种植体支持牙列缺失患者修复中长期的成功率,并得出结论种植体生存率与性别,种植部位关系不大,与修复方法有关。种植体支持的固定义齿预后比可摘义齿好。     

Multicenter retrospective study of cement-retained implant-supported anterior partial prostheses: success and restoration evaluation

PURPOSE: The aim of this multicenter study was to evaluate implant success and restorative complications of cement-retained implant-supported anterior partial prostheses in Jordan. MATERIALS AND METHODS: A retrospective study of all implants with a minimum of 1-year follow-up were used to support fixed, cement-retained restorations from April 2000 until March 2007. The cement-retained implants were loaded with either single- or multiple-tooth replacements. The Fisher exact test was performed to test the presence of any statistically significant difference in success concerning gender or arch of placement. RESULTS: Eighty-seven implants were placed in the anterior region of the mandible or maxilla in 49 patients at multiple clinical practices in Jordan. The age of the patients ranged from 17 to 85 years. Eighteen implants were placed in the mandible and 69 in the maxilla. Three maxillary implants in 2 male patients had 3-mm horizontal bone loss. Those 3 implants are still functioning and were considered surviving implants but not successful implants. Therefore, the implant cumulative survival rate for both arches and genders was 100%. The implant cumulative success rate was 95.78%. Three crowns (maxillary) were dislodged. No significant differences were revealed regarding gender or arch of placement (P > .05). CONCLUSIONS: Cement-retained implants exhibited high survival and success rates among a Jordanian population.     

Long-term marginal periimplant bone loss in edentulous patients

PURPOSE: The aim of this study was to examine the long-term periimplant bone loss in patients treated with implant-supported fixed prostheses in both jaws. MATERIALS AND METHODS: The participants comprised 44 edentulous patients who have been followed for a 15-year period after treatment with a fixed implant-supported prosthesis in the mandible. Thirteen of them also received an implant-supported fixed prosthesis in the maxilla, on average 4.5 years after the mandibular treatment. The periimplant bone level was measured on intraoral radiographs. RESULTS: The long-term results of the implant treatment were successful, and only 1% (3/273) of the implants were lost in the mandible and 7% (5/75) in the maxilla. All but one of the failures occurred before the connection of the prostheses. The mean marginal bone loss around the implants was small (less than 1 mm for a 10-year period after implant placement), and was of similar magnitude in both jaws. However, the individual variation was relatively great. There was no significant difference in marginal bone loss between those who had a maxillary complete denture during the entire observation period and those who had received a fixed implant-supported maxillary prosthesis. Smokers lost more periimplant bone than did the nonsmokers; the difference was significant in the mandible but small and nonsignificant in the maxilla. CONCLUSION: The long-term periimplant bone loss was small and of similar magnitude in the mandible and the maxilla in subjects who had received implant-supported fixed prostheses in both jaws. The prosthetic status in the maxilla, i.e., complete denture or fixed implant-supported prosthesis, had no significant influence on the mandibular periimplant bone loss.     

Prospective clinical trial of dental implants in persons with ectodermal dysplasia

STATEMENT OF PROBLEMS: Ectodermal dysplasia is a hereditary condition in which hypodontia is the second most frequently occurring sign. Hypodontia is associated with lack of development of the alveolar ridge and results in less volume of bone for support of conventional prostheses. Minimal development of the alveolar ridge can affect the bone volume available for the placement of dental implants. Purpose. This clinical trial evaluated the survival of implants placed in individuals with a form of ectodermal dysplasia and severe hypodontia. MATERIAL AND METHODS: Two hundred sixty-four titanium endosteal dental implants were placed in 51 subjects: 37 males and 14 females between the ages of 8 and 68 (mean age 20.5 years, median age 16.5 years). Two hundred forty-three implants were placed in the anterior mandible, and 21 were placed in the anterior maxilla with a 2-stage surgical protocol. Either fixed-detachable dentures or bar-clip overdentures were provided. Subjects were followed up for 0 to 78 months after second-stage surgery. Kaplan-Meier survival rates and curves were produced to describe the survival of the implants for the different age groups and implant locations. Repeated-measures Cox regression models were used to evaluate the hazard ratios for age and location, with alpha=.05 as the criteria for significance. RESULTS: Of the 243 implants placed in the anterior mandible, 221 (91%) survived. Of the 21 implants placed in the anterior maxilla, 16 (76%) survived. Fourteen of the 51 (27%) subjects had a failed implant. All but 2 failures occurred before or at second-stage surgery. Implant-supported prostheses were provided for all patients. CONCLUSION: Within the limitations of this study, the results support the continued use of endosteal dental implants in this patient population with appropriate precautions in the maxilla.     

Treatment outcomes for adolescent ectodermal dysplasia patients treated with dental implants

To evaluate dental implant survival in patients with ectodermal dysplasia (ED). To assess patterns of hypodontia in this patient group. METHOD:. A retrospective analysis of the use of dental implants in ED patients treated at the Royal Children's Hospital, Melbourne. RESULTS: Sixty-one implants were placed into 14 patients (nine male and five female). The mean age of patients receiving maxillary implants was 18 years 6 months (range 17 years 9 months-20 years 0 months) and mandibular implants was 17 years 5 months (range 12 years 2 months-21 years 11 months). The mean follow-up period was 3 years 4 months (range 1 year 18 months-5 years 1 month). Forty-three implants were placed in the anterior mandible, three in the posterior mandible and the remaining 15 in the anterior maxilla. Of the 61 implants placed, 54 [88.5%] successfully integrated and were able to be restored. Three of the 15 implants placed into the anterior maxilla [20%] failed, while four of the 46 in the anterior mandible failed [8.7%]. Five of the 14 patients [35.7%] had at least one implant fail prior to abutment connection. At the 12-month review appointments, 41 of the integrated 54 implants [76%] were reviewed and classed as successful, giving an overall success at follow up of 67.2%. Thirteen implants [21.3%] were unable to be reviewed owing to geographical reasons. Teeth most likely to be present in the maxilla were the central incisors [71%], first molars [54%] and canines [43%], whereas in the mandible they were the canines [53%] and the first premolars and first molars [40%]. CONCLUSIONS: Dental implants can be placed, restored and loaded in ED patients. Maxillary teeth most likely to be present are the central incisors, canines and first molars, whereas in the mandible the canines, first premolars and molars are most likely to be present. Prior to cessation of growth, implant placement in the symphyseal region of the anterior mandible may be performed with caution. Despite the limited numbers and with due consideration to jaw development, the results support the continual use of endosseous dental implants in this group of patients for optimal clinical outcomes.     

Long-term survival and success of oral implants in the treatment of full and partial arches: a 7-year prospective study with the ITI dental implant system

PURPOSE: This study evaluated the long-term survival and success of different implant-supported prostheses supported by ITI implants. MATERIALS AND METHODS: Two hundred fifty consecutive patients were rehabilitated using implant-supported prostheses. Seven hundred fifty-nine implants were loaded. Single-tooth prostheses (n = 106), cantilever fixed partial prostheses (n = 42), fixed partial prostheses (n = 137), fixed complete prostheses (n = 5), implant/tooth-supported prostheses (n = 13), and overdentures (n = 37) were used. The mean follow-up period was 3.85 years. Life table analyses were performed. Implant survival rates were calculated by means of standard life table principles. Statistical analysis was performed to compare the implant survival and success by implant placement site for each type of prosthesis. RESULTS: The cumulative implant survival rates were calculated for implants supporting single-tooth prostheses (95.6%), cantilever fixed partial prostheses (94.4%), fixed partial prostheses (96.1%), fixed complete prostheses (100%), implant/tooth-connected prostheses (90.6%), and overdentures (95.7%). Similar survival and success rates were documented for implants placed in maxillae and mandibles. Implant size did not influence survival. DISCUSSION: Seven-year survival rates were similar for implants supporting single-tooth prostheses, cantilever fixed partial prostheses, fixed partial prostheses, and implant/tooth-supported prostheses. Medium-long term implant survival and success were not influenced by the site (maxilla or mandible). Implant and prosthetic survival rates for overdentures supported by 2 implants were comparable to those for overdentures supported by 3 or more implants. CONCLUSION: Prostheses supported by ITI implants represent a reliable medium-term treatment. (More than 50 references.)     

Evaluating the clinical performance of the Osseotite implant: defining prosthetic predictability

A 5-year prospective, multicenter study is in progress at four private dental practices to determine the cumulative implant survival rate and prosthetic outcome when using the Osseotite dental implant in posterior maxillary and mandibular areas. An interim evaluation after 34.4 months of study progress is presented. A total of 219 Osseotite implants were placed in 74 patients (34 women and 40 men with a mean age of 57.8 +/- 15.2 years) using a conventional two-stage surgical protocol and 3- to 6-month healing time. Subsequently, patients were restored with fixed or removable restorations. Nineteen of the 74 patients reported smoking an average of 13.2 cigarettes per day. Restorative treatments included 40 single-unit restorations; 53 splinted 2-, 3-, 4-, and 5-unit implant-supported maxillary and mandibular prostheses; 4 full-arch fixed maxillary prostheses; 1 mandibular fixed/detachable hybrid prosthesis; and 1 mandibular overdenture. The mean time from implant placement to second stage surgery was 6.2 +/- 2.0 months; from restoration and implant loading to the most recent follow-up evaluation was 20.9 +/- 6.8 months. Of the 219 implants placed, three posterior maxillary implants developed infections and were removed prior to second stage surgery. No implant failures occurred at second stage surgery or after implant loading. Using the Kaplan-Meier method, the cumulative implant survival rate was 100% for anterior implants and 98.4% for posterior implants at 28.5 +/- 5.7 months. The cumulative postloading implant survival rate was 100% for both anterior and posterior implants. The results of this study indicate that the Osseotite dental implant achieved a high rate of integration that remained stable during nearly 2 years of implant function. In addition, because no postloading implant failures have occurred, the Osseotite implant has provided a high level of prosthetic predictability.     

Implant prosthodontic management of partially edentulous patients missing posterior teeth: the Toronto experience

STATEMENT OF THE PROBLEM: The clinical success of implant-supported fixed partial dentures has been documented. However, few studies have reported long-term results or any association between implant outcomes and host determinants. PURPOSE: This study reports on implant and prosthesis outcomes in a group of partially edentulous patients treated with Br?nemark implants in the posterior zones. It also examines factors described in the medical history that may influence implant survival. MATERIAL AND METHODS: The charts of patients treated with implants from 1983 and followed prospectively through December 2001 at the University of Toronto were reviewed. One hundred thirty partially edentulous patients treated with implant-supported restorations in the posterior zones (area distal to mental foramen) were selected. Implant and prosthesis treatment outcomes were recorded and analyzed through the Kaplan-Meier and Cox regression methods (P<.05). RESULTS: A total of 130 patients received 432 Br?nemark dental implants in 174 posterior edentulous spans. The mean age of the patients at the time of insertion of the implants was 50.97 +/- 13.27 years. At 15 years, the overall implant and prosthesis survival rates were 91.6% and 89%, respectively. At 5 years, the survival rate of the wide-platform 5-mm-diameter implants was 76.3%. Implant diameter (P=.0001) and a history of a chronic medical condition (P=.01) were correlated with implant survival outcomes. CONCLUSIONS: High success of implant-supported prostheses in the posterior zones of both the maxilla and mandible. It corroborated other studies that have shown higher failure rates for wide-platform implants, emphasizing the need for proper establishment of clinical trials prior to marketing of new implant designs.     

Placement of posterior mandibular and maxillary implants in patients with severe bone deficiency: a clinical report of procedure

The purpose of this investigation was to modify the method for implant placement in the posterior parts of the arches for fixed implant-supported prostheses using minimally invasive surgery. Eighty-six implants were placed posterior to the mental foramina in patients with severely resorbed mandibles, and 75 implants were placed in the posterior severely resorbed maxilla. Bone grafting from the mandible to the maxillary sinus was performed in 9 patients with severely atrophic maxillae. In all patients, optimal use of the anatomic features of the arch was achieved by tilting the implants. Patients were followed up for 12 to 123 months after prosthesis connection (mean 18 months). Three maxillary implants were lost at the time of abutment connection: 1 in the pterygoid plate, 1 close to the posterior sinus wall, and 1 placed in the palatal cortex. One implant was mobile approximately 1 year later, apparently because of an ill-fitting prosthesis. In the mandible, no implants were lost. The method described for the treatment of edentulous arches represents an alternative therapy to several others currently in use. This minimally invasive surgical procedure should be applicable in an outpatient clinic for treatment of severely resorbed posterior portions of the arches with implant-supported prostheses.     

口腔种植修复临床效果十年回顾研究

目的评估骨结合种植体应用10年的临床效果。方法1994年8月至2004年8月在北京大学口腔医学院·口腔医院口腔种植中心植入的骨结合种植体共5590枚,其中Branemark种植体161枚,Frialit-2种植体1436枚,IMZ种植体1012枚,Ankylos种植体767枚,Camlog种植体2189枚,Komet种植体25枚。全部种植体均在2004年8月前完成上部结构修复,其中固定修复2314例,活动修复315例,共计2629例患者。平均追踪77·2个月(7~121个月)。观察方法为X线检查和临床检查,采用Wheeler存留标准评估,纳入Kaplan-Meier存留曲线统计。结果种植修复体完成时2624例患者对修复效果满意,5例患者对修复体不满意,重作后4例表示满意,1例表示可以接受。随访中有105例患者共178枚种植体确诊为种植体周围炎。有明确记录的共68枚种植体脱落。10年随访累计修复体松动21件,修复体折断4件,烤瓷冠崩瓷51件。据Wheeler存留标准统计10年存留率为96·7%。结论种植修复患者的满意度高,本组种植体的10年存留率达到96·7%。     

Ten-year experience in oral implant rehabilitation of cancer patients: treatment concept and proposed criteria for success.

Between 1988 and 1997, 18 irradiated patients (group 1, 83 implants) and 22 nonirradiated patients (group 2, 92 implants) received resection of the cancer-involved mandible and floor of the mouth and subsequently underwent mandibular rehabilitation with endosseous implants. Implant-supported prostheses were placed in 26 patients, while 13 patients received implant-tissue-supported prostheses. Between 1988 and 1991, patients were restored with implant-tissue-supported prostheses (based on 2 to 4 implants). This strategy was later changed because of the development of denture-related lesions. Since 1992, group 1 patients have been restored exclusively with implant-supported prostheses on 5 to 6 implants; group 2 patients have been rehabilitated alternatively with implant-tissue-supported prostheses on 4 implants. Special criteria for determining the success of implant-supported maxillofacial prostheses were developed. With a mean follow-up period of 37 months, 160 implants (91%) were clinically osseointegrated. Both types of restorations provided sufficient oral rehabilitation. However, only completely implant-supported prostheses avoided soft tissue ulcers. The cumulative success rate was approximately 75% after 7 years for group 1 patients and about 86% after 10 years for group 2 patients. The success rates for implants placed after the change in strategy were approximately 86% (group 1) and 94% (group 2) after 5 years. Based on these experiences, it is suggested that irradiated patients should be restored with exclusively implant-supported prostheses, without any mucosal contact.     

Life table analysis and clinical evaluation of oral implants supporting prostheses after resection of malignant tumors.

Seventeen mostly elderly patients, 13 men and 4 women, were consecutively admitted for implant-prosthodontic treatment after they had undergone resection of malignant tumors in the oral cavity. A total of 53 dental implants (ITI-Straumann) was placed, 12 in the maxilla, 41 in the mandible. The prosthetic rehabilitation consisted of overdenture therapy in 15 patients, and 2 patients were treated with fixed partial prostheses. Thirty-three implants were prescribed for patients who received radiotherapy either before or after implant placement. The average dose varied between 50 and 74 Gy. Eighteen implants were located in grafted bone from the fibula, scapula, or hip. For 2 patients, hyperbaric oxygen therapy was also prescribed after osteoradionecrosis had developed. One implant was lost before prosthetic loading. During an observation period of up to 7 years after loading, 3 more implants were removed. All implant losses occurred in the mandibles of patients who had received radiotherapy. A life table analysis was performed, and the cumulative survival rates, calculated for 2, 3, and 5 years, were 93%, 90%, and 90% respectively. No failures or complications were observed with technical components of the implants or prostheses. All prostheses could be maintained during the entire observation time. Although in the present investigation the survival rate of implants was slightly lower than under standard conditions, the treatment with implant-supported prostheses seemed to be advantageous for patients who had undergone intraoral resections.     

Immediately loaded implants supporting fixed prostheses in the edentulous maxilla: a preliminary clinical and radiologic report

PURPOSE: To evaluate the survival rate of immediately loaded ITI sand-blasted, large-grit, acid-etched (SLA) solid-screw dental implants in the edentulous maxilla after 8 months of loading. MATERIALS AND METHODS: Twenty-eight patients (mean age 63 years) with edentulous maxillae each received 6 implants and 1 implant-supported fixed provisional prosthesis within 24 hours after surgery. After a mean healing time of 15 weeks, the patient received a definitive, screw-retained, implant-supported fixed prosthesis. A total of 168 implants were placed. Clinical parameters were registered after 1 month of loading with the implant-supported fixed prostheses as well as 8 months after implant placement. Radiologic examinations and assessments were made at implant placement and after 8 months. RESULTS: The mean marginal bone level at implant placement was 1.6 mm (range 0 to 5.1; SD 1.1) apical of the reference point (the implant shoulder). The mean marginal bone level at the 8-month follow-up was 3.2 mm (range 0.4 to 5.9; SD 1.1) apical of the reference point. Three implants failed during the healing period. DISCUSSION: The improved results in the present study might be a result of the positive effect of splinting the implants immediately after placement. CONCLUSION: ITI SLA solid-screw implants immediately loaded (ie, loaded within 24 hours of placement) and supporting fixed prostheses had successful survival rates after 8 months. The present results constitute a solid baseline for future follow-up studies.     

前牙区即刻种植22例临床观察

目的:探讨前牙区即刻种植永久修复后的牙龈美学效果。方法:22例前牙缺失病例,行不翻瓣拔牙同期植入28颗种植体,上颌前牙24颗采用非埋入式种植术,下颌前牙4颗采用埋入式种植术,种植体愈合3～4个月进行永久修复。随访12～30个月(平均18个月)。根据Miller牙龈边缘组织退缩分类及Jemt牙龈乳头指数,分别观察种植体永久修复12个月后的牙龈边缘退缩及牙龈乳头状况;根据Albrektsson种植体成功标准,观察所植入的种植体状况。结果:28颗种植体留存率100%。Miller分类,18颗种植体牙龈边缘无退缩;8颗种植体牙龈边缘Ⅰ类退缩;2颗种植体牙龈边缘Ⅱ类退缩。种植修复体近远中Jemt牙龈乳头指数均为Ⅱ级以上。结论:前牙区即刻种植,延期修复是一项较成熟的手术方法,但须严格掌握适应证,才能获得良好的修复效果。