Trends in the incidence of cancer in the Sousse region,Tunisia, 1993–2006

In this article, we analyzed trends in incidence rates of the major cancer sites for a 14‐year period, 1993–2006, in the Sousse region localized in the centre of Tunisia. Five‐year age‐specific rates, crude incidence rates (CR), world age‐standardized rates (ASR), percent change (PC) and annual percent change (APC) were calculated using annual data on population size and its estimated age structure. A total of 6,975 incident cases of cancer were registered, with a male to‐female sex ratio of 1.4:1. ASRs showed stable trends (?0.1% in males, and +1.0% in females). The leading cancer sites in rank were lung, breast, lymphoma, colon‐rectum, bladder, prostate, leukemia, stomach and cervix uteri. For males, the incidence rates of lung, bladder and prostate cancers remained stable over time. While, cancers of colon‐rectum showed a marked increase in incidence (APC: +4.8%; 95% CI: 1.2%, 8.4%) and non‐Hodgkin's lymphoma (NHL) showed a notable decline (APC: ?4.4%; 95% CI: ?8.2, ?0.6). For females, cancers of the breast (APC: +2.2%; 95% CI: 0.4%, 4.0%) and corpus uteri (APC: +7.4%; 95% CI: 2.8%, 12.0%) showed a marked increase in incidence during the study period, while the cervix uteri cancer decreased significantly (APC: ?6.1%; 95% CI: ?9.2%, ?3.0%). The results underline the increasing importance of cancer as a cause of mortality and morbidity in Tunisia. Our findings justify the need to develop effective program aiming at the control and prevention of the spread of cancer amongst Tunisian population.     

Cancer of Corpus Uteri in Tunisia: Epidemiological and Clinicopathological Features

Introduction: The aim of this study was to survey for the first time the burden and characteristics of corpusuteri cancers in Central Tunisia. Design: Characteristics of all cancer cases diagnosed during a 15-year periodwere analyzed based on the data of the Cancer Registry of the Center of Tunisia. Five-year age-specific rates,crude incidence rates, world age-standardized rates (ASR), and annual percent change (APC) were calculatedusing annual data on population size and its estimated age structure. Results: A total of 218 new cases of corpusuteri cancer were recorded. The ASR was 3.1 per 100,000 with a significant increase over time (APC: +7.1%;95% CI: 3.1%, 11.1%). The median age at diagnosis was 60 years and only 20.6% of patients were less than50 years old. The tumor size was higher than 2 cm in 83.5% of cases. Stage I was the most frequent (59.9%)followed by advanced stages (23.2%). Endometrial adenocarcinoma was the most frequent histological type(62.8%) with grade II accounting for 48.5% of cases. Conclusion: Corpus uteri cancer is an important femalecancer with increasing trend over time. These findings justify the need to plan and develop effective programsaiming at the control of the spread of cancer in Tunisia.     

Trends in the incidence of cancer in Qidong, China, 1978-2002

A population-based cancer registry was established in Qidong, Jiangsu Province, China, in 1972, and the trends in incidence rates of the major cancer sites have been analyzed for a 25-year period, 1978-2002. Five-year age-specific rates, crude incidence rates, world age-standardized rates (ASR), percent change (PC) and annual percent change (APC) were calculated using annual data on population size, and estimates of its age structure. The indices of histological verification of diagnosis, death certificate only and proportion of mortality to incidence were employed for assessing the registration quality. A total of 51,933 incident cases of cancer were registered in Qidong from years 1978 to 2002, with a male-to-female sex ratio of 1.9:1. Crude incidence increased markedly over the 25-year period (PC and APC of +55.6% and +2.1%, respectively), but ASR showed a slight decrease (-0.4% in males, and -0.3% in females), indicating that the major part of this is due to population ageing. The leading cancer sites in rank were liver (average ASR = 50.8 per 100,000), stomach (26.7), lung (22.7), colon-rectum (8.9), oesophagus (7.4) and breast (5.4). Cancers of liver, lung, colon-rectum and female breast all showed increases in incidence during the study period, with APCs (ASR) of +0.1%, +1.7% and +1.4% for males, and +0.2%, +0.9%, +1.9% and +1.1% for females, while the cancers of stomach (APC: -3.2% in male, and --2.4% in female) and cervix (APC: -4.7%) showed notable declines. Examination of age-specific rates showed declining trends in the younger generations for liver cancer, but increases for cervix cancer. The results underline the increasing importance of cancer as a cause of mortality and morbidity in a population that is ageing and undergoing profound changes in socioeconomic development and lifestyle. The cancers of high lethality that have been common in the Chinese population (liver, stomach, oesophagus) are showing some evidence of decline, at least in younger generations, but they remain major problems. At the same time, the cancers associated with economically "developed" societies -- lung, colon-rectum and female breast -- are showing increases. The population-based cancer registry is an indispensable tool for providing data for planning and evaluation of programmes for cancer control in all societies.     

Incidence Trend for Non-Hodgkin Lymphoma in the North Tunisian Population, 1998-2009

Background: In 2008, non-Hodgkin lymphoma ranked tenth among other malignancies worldwide with an incidence of around 5 cases per 100,000 in both genders. The latest available rates in Tunisia are from 2006. Materials and Methods: This study aimed to provide an update about NHL incidence for 2009 and its trend between 1998 and 2009 as well as a projection until 2024, using data from the Salah Azaiz Institute hospital registry and the Noth Tunisia cancer registry. Results: In 2009, the NHL incidence in the north of Tunisia was 4.03 cases per 100,000, 4.97 for men and 3.10 for women. Diffuse large B-cell lymphoma (DLBCL) accounted for 63.2% of all NHL subtypes. Between 1998 and 2009, the overall trend showed no significant change. When we compared the trend between two periods (1998-2005 and 2005-2009), joinpoint regression showed a significant decrease of NHL incidence in the first period with an annual percentage change (APC) of -6.7% (95% CI:[-11.2%;-2%]), then the incidence significantly increased from 2005 to 2009 with an APC of 30.5% (95% CI: [16.1%; 46.6%]. The analyses of the different subtype trends showed a significant decrease in DLBCL incidence between 1998 and 2000 (APC:-21.5; 95% CI: [-31.4%;-10.2%]) then the incidence significantly increased between 2004 and 2007 (APC: 18.5; 95% CI: [3,6%;35.5%]). Joint point analysis of the age-period-cohort model projection showed a significant increase between 2002 and 2024 with an APC of 4.5% (%95 CI: [1.5%; 7.5%]). The estimated ASR for 2024 was 4.55/100 000 (95% CI: [3.37; 6.15]). Conclusions: This study revealed an overall steady trend in the incidence of NHL in northern Tunisia between 1998 and 2009. Projection showed an increase in the incidence in NHL in both genders which draw the attention to the national and worldwide burden of this malignancy.     

Colorectal Cancer Incidence Trend and Projections in Tunisia (1994 - 2024)

Objectives: The aim of this study was to describe trends of colorectal cancer incidence during the period 1994-2009 and to generate projections until 2024. Methods: The North-Tunisia Cancer Registry (NTCR) was the source of data for patients with CRC. This registry lists, since 1994, cases of malignant tumors in people living in North Tunisia, including the District of Tunis, the north east and the north west. Cases were classified using the International Classification of Diseases for Oncology. Data were analyzed using R software and Joinpoint one was employed to analyse trends. Projections were performed using the Age Period Cohort based on poisson regression. Results: During the period 1994 to 2009, 6,909 new cases of CRC were registered in Northern Tunisia. The age standardized incidence rate (ASR) increased significantly from 6.4/100,000 in 1994 to 12.4/100,000 in 2009. Trends in CRC incidence was significantly rising with an annual percentage change (APC) of + 3,9% [2.8% -5.1%]. Without effective interventions, the predicted CRC ASR would be 39.3/100,000 [CI 95%: 32,9/100,000 - 48,8/100,000] in 2024. Conclusion: The incidence of colorectal cancer is clearly increasing in Tunisia. Strengthening of screening and primary prevention measures is to be recommended.     

2000~2009年浙江省肿瘤登记地区子宫体癌发病与死亡分析

[目的]分析浙江省肿瘤登记地区2000～2009年子宫体癌的发病与死亡情况。[方法]数据来源于浙江省6个肿瘤登记处上报于浙江省肿瘤防治办公室的肿瘤发病和死亡资料．分别计算发病（死亡）例数、粗发病率（死亡率）、构成比、中标率、世标率、累积率、截缩率以及年度变化百分比等指标。[结果]2000—2009年浙江省6个肿瘤登记地区共计报告子宫体癌新发病例2347例,占女性癌症新发病例的3-35％。子宫体癌发病率为7．92／10万,中标率为4．64／10万,位居女性癌症发病顺位的第9位。子宫体癌发病率呈总体增长趋势,从2000年的5．13／10万增长到2009年的8．69／10万,年度变化百分比（APC）为6．40％（95％CI：3．78％～9．08％）。2000～2009年共报告子宫体癌死亡病例854例,占女性癌症死亡病例的2．56％。子宫体癌死亡率为2．88／10万,中标率为1．41／10万,居女性癌症死因顺位的第11位。子宫体癌死亡率呈现波动增长趋势,年度变化百分比为5．84％（95％CI：-2．70％～15．13％）。[结论]浙江省子宫体癌发病和死亡呈上升趋势,应加强肿瘤防治等措施．以期降低子宫体癌的发病水平。     

上海市区女性生殖系统恶性肿瘤发病趋势分析

目的对1972～1999年上海市区常见的女性生殖系统恶性肿瘤的发病率进行统计,分析其发病趋势及变化原因,为防治措施的制定提供依据.方法根据上海市肿瘤发病登记处收集的1972～1999年的上海市区卵巢癌、宫颈癌、宫体癌和不明部位子宫癌的病例资料和相应年份的人口资料,分别计算各年龄组的年龄别发病率.并采用直接法计算世界人口标化发病率,对数线性回归法计算标化率的年变化率(Annual percentage change,APC),并对病例数进行加权计算.结果1972～1999年上海市肿瘤登记处共登记卵巢癌6106例、宫颈癌8063例,宫体癌3 933例和不明部位子宫癌1 312例.28年来,宫体癌和卵巢癌的标化发病率呈上升趋势,分别从1972～1974年的2.49/10万和4.77/10万上升至1996～1999年的4.75/10万和6.88/10万,年增长率分别为3.0%和2.0%.同期宫颈癌的标化发病率从26.66/10万快速下降至2.18/10万,年下降率达10.5%.不明部位子宫癌的标化发病率亦呈下降趋势(P＜0.01).宫体癌以55～64和65～74岁组发病率上升最快,年增长率分别为2.5%和3.3%.卵巢癌各年龄组的发病率均有上升趋势,年变化率都在1.0%以上.宫颈癌发病率下降最快的年龄组是45～54和55～64岁组,25～34和35～44岁组的发病率在近几年有升高趋势.结论上述肿瘤的发病率及年龄别发病率的变化趋势提示,上海女性生活方式和环境因素的改变可能是导致这种变化的重要原因.     

2009—2015年甘肃省肿瘤登记地区子宫体癌发病与死亡特征分析

目的 分析甘肃省肿瘤登记地区2009—2015年子宫体癌发病和死亡流行状况及变化趋势,为甘肃省子宫体癌的防治提供依据.方法 审核整理2009—2015年甘肃省肿瘤登记地区子宫体癌发病(死亡)率、构成比、中国人口标化率(中标率)和世界人口标化率(世标率)等,分析年龄别发病及死亡情况,并通过Joinpoint回归模型计算年...     

Time Trends of Cancer Incidence in Urban Beijing,1998-2007

Objective:To report the time trends of cancer incidence in urban Beijing from 1998 to 2007.Methods:All data were obtained from Beijing Cancer Registry from 1998-2007 in urban Beijing.Time trends of incidence rate of cancer were assessed by annual percentage change(APC) of age-standardized incidence rate(ASR) of world standard population during this 10-year period.Results:For all 156851 cancer cases combined,the incidence rate rose in both males and females,with an APC of 2.23% and 3.74%,respectively.The ...     

Lung cancer in central Tunisia: epidemiology and clinicopathological features

Lung cancer is the most common cancer worldwide but data from Tunisia are limited. The aim of this research was to describe the epidemiology, pathology and clinical features of lung cancer in Central Tunisia. All lung cancer cases diagnosed during a 15-year period were analyzed based on the data of the Cancer Registry of the Center of Tunisia. Five-year age-specific rates, world age-standardized rates (ASR), and annual percent change were calculated using annual data on population size and the estimated age structure. A total of 1,882 incident cases of lung cancer were registered (1,782 males, 100 females). The median age at diagnosis was 64 years for males and 61 years for females, with ASRs of 35.2 per 100,000 among males and 1.5 among females. Over time, there were significant decreasing trends by -6.5% (95% CI: -12.9%; -0.2%) for females and a stable incidence for males at an annual rate of +0.2% (95% CI: -1.6%; +1.8%). The predominant histological type was squamous cell carcinoma in males (36.9%) and adenocarcinoma in females (52%). During 2003-2007, adenocarcinoma became the most frequent (33.7%) followed by squamous cell carcinoma (30.3%) in males. The majority of tumor cases were diagnosed at advanced stages (79.9%). In conclusion, lung cancer has remained the most common cancer diagnosed at advanced stages among Tunisian men. Our findings justify the need to plan and develop effective programs aiming at the control and prevention of the spread of lung cancer in Tunisia.     

Cancer Incidences in Rural Delhi - 2004-05

There are no data available on cancer incidence pattern in rural Delhi. This is the first report on cancerincidence among Delhi Rural population during 2004-05 which gives the first hand information on cancerincidence. The data for this report has been collected by Delhi Population based cancer registry. The sources forcancer registration are more than 162 Government Hospitals/centers and 250 private hospitals and nursinghomes. A total of 594 cancer cases with 317 males and 277 females were registered during the period 1st January2004 to 31st December 2005. The age adjusted (world population) incidence rates for all sites were 55.2 per100,000 for males and 47.7 per 100,000 for females. The leading sites of cancer among Delhi Rural males wasoral cavity (ASR: 8.0 per 100000) followed by lung (ASR: 6.5), larynx (ASR: 4.0) and bladder (ASR: 4.1). Infemales cervix uteri (ASR: 10.3 per 100,000) was the most common site of cancer followed by breast (ASR: 7.8),gallbladder (ASR: 3.5) and ovary (ASR: 3.3). The overall incidence rates of cancer in Delhi Rural werecomparatively very less than Delhi Urban. A statistically significant difference was also found between DelhiRural and Delhi Urban in incidence rates (ASR) for first four common sites. The rates in Delhi Rural are alsocomparatively lower than other rural registries situated in India.     

Characteristics and trends in incidence of childhood cancer in Beijing,China, 2000-2009

Objective： To investigate the characteristics and incidence trends of childhood cancer in Beijing, China, from 2000 to 2009. Methods： A total of 1,274 cases with childhood cancer in Beijing from 2000 to 2009 were included in the study. All rates were age-standardized using the direct method to the world standard population and expressed per million person-years. Incidence trends were characterized by calculating annual percent change （APC） usingJoinpoint Regression Program. Results： The crude incidence rate was 106.47 per million [age-standardized rate （ASR） 113.34] between 2000 and 2009 in Beijing with the most common diagnoses, leukemia （N=505, 39.64%, ASR 45.20）, followed by central nervous system （CNS） tumors （N=228, 17.90%, ASR 19.28） and lyrnphoma （N=91, 7.14%, ASR 6.97）. The incidence for all childhood cancers combined has increased during the study period, with an APC of 5.84% [95% confidence interval （95% CI）： 1.0-10.9] after adjusted by world population. The ASR of all combined cancers in boys showed a slight, but no significant increase, with an APC of 5.33 % （95 % CI： -0.6- 11.6）; for girls, the trends increased significantly, with an APC of 6.54% （95% CI： 1.5-11.8）. Conclusions： The incidence rate of childhood cancer in Beijing was higher than the average level of China and lower than that of western countries. The incidence trends of childhood cancer, especially leukemia among girls showed a significantly increase from 2000 to 2009. While among boys, no substantially change was seen during the observed time period. Some sex-specific trends by subcategories and trends of major cancers in different age groups by cancer site merit further investigation.     

Cancer in the Gambia: 1988-97

We describe the incidence of cancer in The Gambia over a 10-year period using data collected through the Gambian National Cancer Registry. Major problems involved with cancer registration in a developing country, specifically in Africa are discussed. The data accumulated show a low overall rate of cancer incidence compared to more developed parts of the world. The overall age standardized incidence rates (ASR) were 61.0 and 55.7 per 100 000 for males and females, respectively. In males, liver cancer was most frequent, comprising 58% of cases (ASR 35.7) followed by non-Hodgkin lymphoma, 5.4% (ASR 2.4), lung 4.0%, (ASR 2.8) and prostate 3.3% (ASR 2.5) cancers. The most frequent cancers in females were cervix uteri 34.0% (ASR 18.9), liver 19.4% (ASR 11.2), breast 9.2% (ASR 5.5) and ovary 3.2% (ASR 1.6). The data indicate that cancers of the liver and cervix are the most prevalent cancers, and are likely to be due to infectious agents. It is hoped that immunization of children under 1 year against hepatitis B will drastically reduce the incidence of liver cancer in The Gambia.     

Cervical Cancer in Khon Kaen,Thailand: Analysis of 1990-2014 Incidence Data and Prediction of Future Trends

Background: Cervical cancer is the second most common cancer of women in Thailand. There have been no reportsof incidence and future in Khon Kaen, a province in northeastern Thailand, where the relatively high prevalence givesevaluation of cervical cancer screening a high priority. Objectives: To determine cervical cancer incidence rates inKhon Kaen for 1990–2014 and predict future trends until 2029. Methods: Cancer incidence data from the Khon Kaenpopulation-based cancer registry were analyzed and age-standardized incidence rates (ASR) were estimated. Joinpointanalysis and age-period-cohort modeling were applied for data from 1990 to 2014 and the Nordpred package wasemployed to project trends from 2015 to 2029. Results: Between 1990 and 2014, a total of 3,258 cases were diagnosedwith ICD-O code C53 (invasive cervical cancer). Before 2005, an annual percentage change (APC) varied widely, withoutliers in 1993 and 1999. The APC computed with the Joinpoint software decreased at -2.8% (95% CI;-4.5 to -1.1)per year on average. After 2005, a rise was noted until 2008, after which a drop became apparent with an APC of-8.0% (95% CI; -14.5 to -1.1) per year on average. Both period and cohort effects played a role in shaping the decreasein incidence. The three projection method suggested that incidence rates would continue to decrease in the future.Conclusions: A decreasing trend in incidence of cervical cancer in Khon Kaen was noted from 1990 to 2014 with aprediction of continuous decrease until 2029. Maintenance and improvement of the screening program is advised.     

2010-2014年浙江省肿瘤登记地区子宫体癌发病与死亡分析

目的近年来子宫体癌发病呈现明显上升趋势,为了解浙江省近年来女性子宫体癌流行现状,现分析2010-2014年浙江省肿瘤登记地区子宫体癌的发病与死亡情况。方法数据来源于浙江省肿瘤防治办公室14个登记处(浙江省)上报的子宫体癌发病、死亡和人口资料,分别计算发病(死亡)例数、粗发病率(死亡率)、构成比和顺位、中国标准人口构成(中标率)、Segi’s标准人口构成(世标率)、累积率、截缩率、年龄别发病率(死亡率)、发病率(死亡率)年度变化百分比(annual change percent change,APC)及95%CI等指标。结果2010-2014年浙江省14个肿瘤登记地区共报告子宫体癌新发病例2767例,占女性癌症新发病例的3.08%。子宫体癌发病率为9.46/10万,中标率为6.11/10万,位居女性癌症发病顺位的第8位。子宫体癌发病率呈波动增长趋势,从2010年的9.31/10万上升至2014年的10.28/10万,APC为1.89%(95%CI:-2.90~6.91)。2010-2014年共报告子宫体癌死亡病例797例,占女性癌症死亡病例的2.10%。子宫体癌死亡率为2.72/10万,中标率为1.58/10万,位居女性癌症死因顺位的第13位。子宫体癌死亡率呈现波动下降趋势,由2010年的2.76/10万降至2014年的2.52/10万,APC为-4.28%(95%CI:-13.82~6.33)。结论浙江省子宫体癌发病率呈波动上升趋势,但死亡率呈波动下降趋势,应通过提高早诊早治比例、提高女性自我防护意识和倡导健康生活方式等综合措施做好子宫体癌防控。     

Trend analysis of cancer incidence in Japan using data from selected population-based cancer registries

Population-based cancer registries are operated by over 80% of prefectures in Japan. However, only a limited proportion of the registries can provide long-term incidence data. Here, we aimed to establish a method for monitoring cancer incidence trends in Japan using data from selected prefectures. Based on the availability of long-term (≥ 20 years) high-quality data, we collected incidence data from five prefectures (Miyagi, Yamagata, Fukui, Osaka, and Nagasaki), which included an annual average of 54,539 primary cancer cases diagnosed between 1985 and 2004. Cancer mortality data for 1995-2004 were obtained from the vital statistics. Representativeness and homogeneity of the trends were examined by funnel plot analysis of log-linear regression coefficients calculated for the most recent 10 years of data (1995-2004) of age-standardized rates (ASR). The ASR of incidence for five prefectures in total (5-pref total) showed a significant decrease, with an annual percent change (APC) of -1.0 (95% confidence interval [CI] -1.4: -0.6) for males and -0.4 (95% CI -0.8: -0.1) for females. Excluding data from Osaka (4-pref total) reversed the decreasing trend; the corresponding APC was +0.4 (95% CI -0.2: +1.0) for males and +0.7 (95% CI +0.5: +0.9) for females. The APCs for the ASR of mortality for the 4-pref total (males, -1.5; females, -1.3) were more representative of nationwide data (males, -1.4 [95% CI -1.7: -1.2]; females, -1.1 [95% CI -1.4: -0.9]) than those for the 5-pref total (males, -1.7; females, -1.4). We conclude that using data from Miyagi, Yamagata, Fukui, and Nagasaki prefectures, with continuous monitoring of the representativeness of the data, is a provisionally relevant way to evaluate cancer incidence trends in Japan.     

肝癌流行趋势的改变:基于启东40年癌症登记资料的分析

[目的]探讨启东市1972-2011年肝癌发病趋势的变化,为肝癌的流行趋势及预防控制的评估提供决策依据。[方法]基于启东市癌症发病登记数据库,计算肝癌粗发病率（CR）、中国人口标化率（中标率）、世界人口标化率（世标率）、35-64岁截缩率、0-74岁累积率、累积风险、变化百分比（PC）及年均变化百分比（APC）等指标。[结果]1972-2011年启东肝癌发病28 398例（男性21 404例,女性6 994例）,占全部癌症发病的30.61%,位居癌症发病第1位。CR为63.17/10万,中标率和世标率分别为39.32/10万和50.71/10万;35-64岁截缩发病率为119.06/10万;0-74岁累积发病率为5.28%;肝癌发病的累积风险为5.15%。40年间肝癌发病的CR、中标率、世标率的变化百分比（PC）分别为40.77%、-44.35%与-37.24%,年均变化百分比（APC）分别为1.44%、-1.14%、-0.83%。各时期肝癌发病率显示45-74岁各年龄组发病率趋势稳定,75岁及以上年龄组的发病率有所上升,而35-44及以下各年龄组的发病率均有下降趋势。年龄—出生队列方法分析显示45岁以下各年龄组出生队列的发病率有明显的下降趋势。[结论]启东40年来肝癌粗发病率（绝对数）虽呈上升趋势,但标化率已呈明显的下降趋势;青年人中肝癌发病率的下降尤为显著。     

启东市1972~2011年胃癌发病趋势分析

[目的]探讨启东市1972-2011年胃癌发病率变化趋势。[方法]基于启东市1972-2011年癌症发病登记数据库,对胃癌发病率作性别、年龄别、时间趋势分析,计算指标包括粗发病率、中国人口标化率（中标率）、世界人口标化率（世标率）、35-64岁截缩率、0-74岁累积率、累积风险、变化百分比（PC）及年均变化百分比（APC）等。[结果]1972-2011年启东胃癌发病15 401例（男性9804例,女性5597例）,粗发病率为34.26/10万,占全部癌症发病的16.60%,位居癌症发病第2位。中标率和世标率分别为16.25/10万和25.59/10万;35-64岁截缩发病率为40.03/10万;0-74岁累积发病率为3.15%,累积风险为3.10%。40年间胃癌发病的粗率、中标率和世标率的变化百分比（PC）分别为＋21.90%、-55.32%与-51.20%,年均变化百分比（APC）分别为＋0.49%、-2.12%、-2.06%。各时期胃癌发病率显示25-74岁各年龄组的发病率有下降趋势。年龄—出生队列方法分析显示,25-79岁各年龄组出生队列发病率有下降趋势。[结论]启东胃癌40年粗发病率总体维持在较高水平,但标化发病率已呈下降趋势。启东人群中胃癌的进一步下降,是可以预期的。     

Changing Trends in Incidence of Ovarian Cancer - the Indian Scenario

Ovarian cancer has emerged as one of the most common malignancies affecting women in India. The presentcommunication reports the trends in the incidence rate of ovarian cancer for Indian women. The data publishedin Cancer Incidence in Five Continents for various Indian registries for different periods and / or publication bythe individual registries served as the source material. Mean annual percentage change (MAPC) in rates wascomputed using relative differences between two time periods. During the period 2001-06, the age-standardizedincidence rates (ASR) for ovarian cancer varied from 0.9 to 8.4 per 100,000 person years amongst variousregistries. The highest incidence was noted in Pune &Delhi registries. The Age Specific Incidence Rate (ASIR)for ovarian cancer revealed that the disease increases from 35 years of age and reaches a peak between the ages55-64. The trend analysis by period showed an increasing trend in the incidence rate of ovarian cancer in mostof the registries, with a mean annual percentage increase in ASR ranged from 0.7% to 2.4 %. Analysis of databy ASIR revealed that the mean annual percentage increase was higher for women in the middle and older agegroups in most of the registries. Estimation of annual percent change (EAPC) in ovarian cancer by Poissonregression model through Maximum Likelihood Estimation (MLE) for the data of 3 population-based cancerregistries vs. Mumbai, Chennai and Bangalore for the period 1983-2002 revealed that linear regression wasfound to be satisfactory fit between period and incidence rate. Statistically significant increase in EAPC wasnoted with the crude rate (CR,) ASR, and ASIR for several age-groups. Efforts should be made to detect ovariancancer at an early stage by educating population about the risk factors. Most of the ovarian cancers areenvironmental in origin and consequently, at least in principle avoidable.     

2009—2015年甘肃省肿瘤登记地区甲状腺癌流行特征及变化趋势

目的 分析甘肃省肿瘤登记地区2009—2015年甲状腺癌发病与死亡的流行状况.方法 审核整理2009—2015年甘肃省肿瘤登记地区甲状腺癌发病(死亡)例数、发病(死亡)率、构成比、中标率、世标率等,分析年龄别发病、死亡情况,并通过Jointpoint回归模型计算年度变化百分比(Annual percentage cha...