磁共振导航下细针穿吸诊断头颈深部肿块的应用价值

目的:评价磁共振导航下细针穿吸诊断头颈深部肿块的应用价值。方法:对12例头颈深部肿块患者行磁共振导航定位引导下细针穿吸细胞学检查,男9例,女3例,年龄15-63岁。肿块位于颞下窝6例,腮腺深叶3例,翼下颌间隙2例,咽旁间隙1例。结果:所有12例肿块经磁共振导航下穿吸针均显示达到肿块中心;穿吸细胞学检查6例与术后病理符合,1例不符:另5例穿吸细胞学为炎症,未进行手术探查,现随访正常。穿吸诊断准确率为91.67％,敏感度为80％,特异度为100％;穿吸过程中无明显并发症。结论:磁共振导航下细针穿吸细胞学检查是一种定位准确、诊断准确率高且安全的检查方法,尤其适应于头颈部深部肿块的诊断。     

下颌切迹入路细针穿吸细胞学检查在面侧深部肿物诊断中的应用价值

目的:评价经下颌切迹入路的细针穿吸细胞学检查(FNAC)在面侧深部肿物诊断中的应用价值。方法:应用细针穿吸方法,对40例面侧深部肿物患者进行细胞学检查。男24例,女16例;年龄3～75岁,平均年龄43.28岁。将细胞学检查结果与术后组织病理学检查结果或随访资料进行比较,计算FNAC诊断准确率及在区别肿瘤与非肿瘤、恶性肿瘤与良性病变上的敏感度和特异度。结果:FNAC诊断准确率为80.00%;诊断肿瘤与非肿瘤的敏感度为80.77%,特异度为100.00%,5例患者为假阴性,假阴性率为19.23%,假阳性率为0;诊断恶性肿瘤与良性病变的敏感度为80.00%,特异度为88.00%。3例患者为假阴性,假阴性率为20.00%,3例患者为假阳性,假阳性率为12.00%。结论:FNAC是一种安全性好,操作简单,患者易于接受的诊断方法,在不易做切除及切取活检的面侧深部肿物的定性诊断中有较高的准确率,能准确区别肿瘤与非肿瘤、恶性肿瘤与良性病变,为临床治疗提供依据。     

细针吸取细胞学检查对腮腺肿物的诊断价值

目的探讨细针吸取细胞学检查(FNAC)对腮腺肿物的诊断价值。方法回顾性分析2013—2016年首都医科大学附属北京友谊医院口腔科98例行FNAC的腮腺肿物的病历资料,以最终组织病理学诊断结果为金标准。计算FNAC对各腮腺肿物诊断的准确率,对非肿瘤性病变及恶性肿瘤诊断的灵敏度、特异度、阳性预测值及阴性预测值。结果 FNAC诊断腮腺肿物的准确率依次为:非肿瘤性病变(88.9%)>良性肿瘤(74.0%)>恶性肿瘤(56.3%);FNAC诊断非肿瘤性病变灵敏度:88.9%,特异度为:91.0%,阳性预测值:50.0%,阴性预测值:98.8%;FNAC诊断腮腺恶性肿瘤灵敏度:87.5%,特异度为:97.6%,阳性预测值:87.5%,阴性预测值:97.6%,假阳性病例为1例腮腺囊肿和1例多形性腺瘤,假阴性病例为2例恶性淋巴瘤误诊为沃辛瘤。结论 FNAC对腮腺非肿瘤性病变及良性肿瘤的诊断准确率高,恶性肿瘤的灵敏度特异度好,是一种有较好诊断价值的诊断手段,假阳性及假阴性病例,需要结合超声引导下穿刺、免疫组化及术中冰冻结果。     

涎腺肿块的细针吸取细胞学诊断研究

目的 通过对细针吸取细胞学(fine needle aspiration cytology,FNAC)与病理诊断的比较,评价本组细针吸取细胞学在涎腺肿块术前诊断的价值.方法 采用"友谊式"细针穿刺器,对81例涎腺肿块进行FNAC检查,将其结果与术后组织病理结果对照,得出FNAC诊断准确率,同时计算微小组织病理学诊断的准确率.结果 本组FNAC定性诊断准确率达92.59%,误诊率7.41%;组织学分类完全符合率达67.90%,基本符合率24.69%,不符合率7.41%;微小组织病理学诊断准确率达85.71%,误诊率14.29%.结论 FNAC对涎腺肿块的定性诊断的准确性较高,对术前诊断有重要的参考意义.由于FNAC诊断不同类型涎腺肿块的完全符合率不同,其临床可参考性也不同.     

多种方法联合在腮腺肿物诊断中的应用

近年来 ,我们应用包括腮腺区B超、细针吸细胞学检查、腮腺造影和腮腺区CT在内的多种方法联合对腮腺区肿块进行诊断 ,明显的提高了诊断符合率 ,且适合基层医院开展 ,现报告如下 :1　临床资料1.1　一般资料本组共 66例腮腺区肿块患者 ,男 3 7例 ,女 2 9例 ,年龄 2～80岁。良性肿瘤 3 9例 ,恶性肿瘤 2 1例 ,其它 6例。所有病例均行腮腺区B超、细针吸细胞学检查、腮腺造影和腮腺区CT检查 4种方法中的 2种或 3种联合检查 ,其中 17例行B超与细针吸细胞学联合检查 ,13例行B超与CT联合检查 ,15例行B超与造影联合检查 ,10例行CT与细针吸细胞学…     

细针吸取活检对腮腺肿瘤的诊断价值

目的：探讨细针吸取活检对腮腺肿瘤的诊断价值。方法：68例非淋巴造血系统及非囊性病变的原发性腮腺肿瘤患者，术前行细针吸取细胞学检查，对40例良性的28例恶性肿瘤按不同组织来源分类；将穿吸结果与术后病理检查对照，按临床流行病学方法计算符合率，特异符合率，假阳性率和假阴性率。结果：细针吸取活检对良性或恶性肿瘤的诊断符合率无显著性差异（P＞0．05）；21例多形性腺瘤的符合率为100％，特异符合率为90．48％；8例非腺上皮来源良性肿瘤的符合率为50％，40例良性肿瘤的假阳性率为0，28例恶性肿瘤的假阴性率为17．86％，5例粘液表皮样癌中，4例报告倾向“多形性腺瘤”，结论：细针吸取活检对多形性腺瘤的诊断价值较大，对非腺上皮性良性肿瘤的诊断傺 大；粘液表皮样癌易误诊为多形性腺瘤。     

细针吸取细胞学在口腔颌颈部包块诊断中的应用

目的:探讨细针吸取细胞学检查(FNAC)对口腔颌颈部包块的诊断价值.方法:运用细针穿刺器对195例口腔颌颈部包块进行FNAC检查,并与包块切除术后病理组织学(HPD)的诊断结果进行对比.结果:FNAC检查定性诊断准确率90.8%,误诊率9.2%:HPD的结果与FNAC的组织学结果相比两者间无差异性(p＞0.05).FNAC检查后无并发症发生,也未发现肿瘤转移与复发.结论:细针穿刺器吸取细胞对口腔颌颈部包块诊断具有安全,简便等优点,有较高的诊断准确率.     

腮腺肿块细针抽吸细胞学诊断的价值

本文目的是评价细针抽吸细胞学在腮腺肿块诊断中的价值。 患者和方法 回顾1990.1～1998.12,228例术前行细针抽吸细胞学(FNAC)的腮腺肿块患者,以前未行治疗并无腮腺或非腮腺肿瘤病史。所有患者均行保留或不保留面神经单侧腮腺切除或腮腺次全切或全切。其中男105例,女123例。年龄16～97岁,平均55岁。病理示良性163例(150例肿     

口腔颌面肿块细针吸细胞学分析

细针吸细胞学应用于口腔颌面肿块的诊断准确性高,已在临床上广泛应用.我院1993年～1995年对86例口腔颌面肿块患者术前行细针吸细胞学检查,术后行病理组织学检查,结果对照分析如下.     

116例口腔颌面颈部肿块细针吸取细胞学诊断分析

目的：研究细针吸取细胞学检查（ＦＮＡＣ）对口腔颌面颈部肿块的诊断价值。方法：运用“友谊式细针穿刺器”对１１６例口腔颌面颈部肿块进行ＦＮＡＣ检查，将其结果与肿块术后病理组织学诊断结果对比。结果：ＦＮＡＣ检查定性诊断的准确率为９０５２％，误诊率为９４８％，假阳性仅１例；ＦＮＡＣ检查所定肿块组织类型与病理组织学诊断结果完全一致者达５０％；ＦＮＡＣ检查后无１例并发症发生，至今未发现肿块转移与复发。结论：①“友谊式细针穿刺器”吸取细胞诊断口腔颌面颈部肿块，简便安全，实用快捷。②口腔颌面颈部肿块ＦＮＡＣ检查定性诊断的可靠性较高，在确定肿块具体类型方面，仅供参考。     

Fine needle aspiration cytology and frozen section in the diagnosis of malignant parotid tumours

The aim of this study was to determine the value of fine needle aspiration cytology (FNAC) and frozen section (FS) in the diagnosis of malignant parotid tumours. One hundred and thirty-eight patients who underwent FNAC and FS of a parotid tumour between 2006 and 2011 were analyzed retrospectively. The sensitivity, specificity, and positive and negative predictive values of FNAC and FS were determined using final histological diagnosis as the gold standard. Of the 138 tumours assessed in our study, 30 were malignant and 108 benign. For FNAC, the sensitivity was 73%, specificity 87%, positive predictive value 61%, and negative predictive value 90%. For FS, the sensitivity was 80%, specificity 98%, positive predictive value 92%, and negative predictive value 94%. Four false-negative results by FNAC were corrected by FS, and surgery was completed. Two false-positive results were identified by both FNAC and FS. FNAC is an important examination that provides valuable information for the preoperative diagnostic work-up and alerts the surgeon to the possible presence of malignancy. However, FNAC cannot be used alone, and FS has a very important place in the intraoperative management of parotid tumours.     

Fine-needle aspiration cytology: a reliable tool in the diagnosis of salivary gland lesions

J Oral Pathol Med (2012) 41 : 106–112 Background: Fine‐needle aspiration cytology (FNAC) is used as the main initial diagnostic investigation for lumps in the head and neck region. Major salivary glands and some minor salivary glands are easily accessible; therefore, they are optimal targets for FNAC. The aim of this study was to discuss the advantages and pitfalls of FNAC as compared to histopathology in the salivary gland lesions. Material and methods: A total of 127 FNAC were carried out on salivary gland lesions from January 2006 to December 2010 – a 5‐year period. Histopathological follow‐up data were obtained in 56 cases. The study was conducted to examine the sensitivity, specificity, and accuracy of FNAC for salivary gland swellings in comparison with histopathology. Results: The male‐to‐female ratio was 2.4:1. Parotid gland was involved in 51.1%, submandibular gland in 37%, sublingual gland in 4.7%, and minor salivary glands in 7% of patients. There were 55.9% cases of non‐neoplastic lesions and 44.1% cases of neoplastic lesions on biopsy. Sensitivity, specificity, positive predictive value, and negative predictive value of FNAC for malignant neoplastic lesions were 84.61%, 86.48%, 68.75%, and 94.11%, respectively, whereas for benign neoplastic lesions, they were 84.61%, 91.66%, 91.6%, and 85%, respectively. Conclusion: Fine‐needle aspiration cytology is found to be a good sensitive and specific technique for the diagnosis of most of the salivary gland lesions. FNAC should be adopted as an initial investigation for all salivary gland swellings in conjunction with other investigations where appropriate.     

Fine-needle aspiration cytology of salivary gland tumours: a 10-year retrospective analysis

Introduction

The aim of this study was to evaluate the sensitivity, specificity, diagnostic accuracy, positive predictive value (PPV) and negative predictive value (NPV) of fine-needle aspiration cytology (FNAC) of salivary gland tumours performed at a tertiary cancer hospital over a time period of 10?years.

Materials and methods

A retrospective analysis was carried out between 1995 and 2004 to review the cases of patients with salivary gland tumours who had undergone pre-operative FNA and for whom definite histology was either by tru-cut biopsy or by histopathological examination of the operative specimen.

Results

A total of 107 cases of salivary gland tumours were treated during that period, but only 82 cases diagnosed by FNAC could be correlated with histological and clinical data and were considered for this study. The sensitivity, specificity, diagnostic accuracy, PPV and NPV were estimated considering 54 benign and 28 malignant cases. Sensitivity was 90% (28/31), specificity was 98% (54/55), diagnostic accuracy was 95.1% (82/86), PPV was 96% and NPV was 94%.

Discussion

This study confirms that FNA cytology is a technique that offers high sensitivity, specificity and diagnostic accuracy in salivary gland tumour diagnosis.     

单光子发射型计算机断层成像在腮腺肿块诊断中的应用评价

目的探讨单光子发射型计算机断层成像（ｓｉｎｇｌｅ ｐｈｏｔｏｎ ｅｍｉｓｓｉｏｎ ｃｏｍｐｕｔｅｄ ｔｏｍｏｇｒａｐｌｙ，ＳＰＥＣＴ）对腮腺肿块术前定性诊断的价值。方法 对４５例腮腺肿块患者术前１￣２周行腮腺区ＳＰＥＣＴ检查，以５价＾９９锝标记的二巯基丁二酸钠「ｔｅｃｈｎｅｔｉｕｍ－９９ｍ（Ｖ）ｄｉｍｅｒｃａｐｔｏｓｕｃｃｉｎｉｃ ａｃｉｄ，＾９９ｍＴｃ（Ｖ）ＤＭＳＡ」为显像剂，结果与病理诊断、临     

The role of operator experience in fine needle aspiration cytology of head and neck masses

Fine needle aspiration cytology (FNAC) was performed on 95 patients presenting with a mass in the head and neck region, where a subsequent surgical pathological diagnosis and adequate documentation were available. In this group, 70% of the samples were found to be of diagnostic yield. Of these, the number of true-positives was 27, and true-negatives 35. This gives a sensitivity and specificity of 90% and 97%, respectively. The accuracy was 100% when performed by a consultant and 91% when performed by junior staff. These sensitivity and specificity levels compare favourably with those reported in other studies using FNAC in head and neck lesions. Greater experience of the operator appears to improve the accuracy rate. FNAC is a useful diagnostic tool for head and neck tumours, as shown by the high specificity and sensitivity rates in this study.     

The application of magnetic resonance imaging-guided fine-needle aspiration cytology in the diagnosis of deep lesions in the head and neck.

PURPOSE: Image-guided fine-needle aspiration cytology (FNAC) may be useful as an alternative diagnostic approach to lesions in the head and neck. This study reports on the use of magnetic resonance imaging (MRI)-guided FNAC for diagnostic evaluation of deep lesions in this region. MATERIALS AND METHODS: This was a prospective study of 12 patients with deep lesions in the head and neck who underwent MRI-guided FNAC at the Shanghai 9th People's Hospital. A 0.2-T open magnet was used for MRI and localization of the 20-gauge MRI-compatible needle. All of the aspirated samples were stained with hematoxylin and eosin and examined by a cytopathologist. RESULTS: The needle in all 12 cases was displayed on MRI in the central portion of the lesion under the guidance of MRI; 12 of 12 patients (100%) had diagnostic aspirations and none needed open biopsy for more specific histologic interpretation. Six of these 12 patients with tumors (4 malignant, 2 benign) underwent operative treatment with positive postoperative pathologic results. One patient had a diagnosis of inflammation. The diagnostic accuracy was 91.67% (11 of 12), the sensitivity was 85.71% (6 of 7), and the specificity was 100% (5 of 5). There were no false-positive results and 1 false-negative result, for a false-negative rate of 14.29% (1 of 7). All aspiration procedures were well tolerated and without complications. CONCLUSIONS: MRI-guided FNAC is a cost-effective tool for establishing tissue diagnosis as a primary investigative modality. It is helpful and accurate in the diagnosis of deep lesions in the head and neck and in follow-up of patients, thereby avoiding further surgical intervention.     

The accuracy of fine needle aspiration cytology in the clinical diagnosis of minor salivary gland tumours

The objective of this study was to investigate the accuracy of fine needle aspiration cytology (FNAC) and biopsy for the clinical diagnosis of minor salivary gland tumours (MSGTs). This retrospective study of 32 MSGT cases was conducted over a 5-year period. Clinical features including age, sex, and location of the tumour were obtained from the patient clinical records. All cases were also assessed histologically according to the 2017 World Health Organization Classification of Head and Neck Tumours. The results of FNAC and biopsy were correlated with those of histopathology, and their sensitivity, specificity, and diagnostic efficacy were calculated using histopathology as the gold standard. Eighteen malignant MSGTs (56.3%) and 14 benign MSGTs (43.8%) were diagnosed by pathological diagnosis. The most common malignant tumour was mucoepidermoid carcinoma (seven cases, 38.9%). Most benign cases were pleomorphic adenomas (13 cases, 92.9%). FNAC was performed for 23 cases and biopsy for 13 cases. The sensitivity and specificity of FNAC were 66.7% and 91.0%, respectively, while those of biopsy were 90.0% and 100.0%, respectively. Although FNAC is a minimally invasive and cost-effective procedure, it is less accurate than biopsy in the assessment of MSGTs. Repeated FNAC or biopsy should be considered in negative and unsatisfactory FNAC cases.