Congenital hip dislocation and subtrochanteric pseudoarthrosis: Hip replacement based on computer-aided analysis

We describe the technique and outcome of resection hip arthroplasty with external fixator for malignant pelvic tumors involving the innominate bone. We used the procedure in 5 patients, all followed for more than 2 years. 4 of the patients are alive and 1 died of pulmonary metastasis. None of the patients experienced local tumor recurrence or infection. Lower limb function in 3 of the 5 patients was more than 70% with Enneking's criteria (Enneking et al. 1993). These 3 patients could walk without support and passively flex the hip up to 90 degrees. This resection hip arthroplasty allows early weight bearing with hip motion. We believe it is an excellent alternative to other procedures, such as endoprosthetic replacement, reconstruction with allograft or arthrodesis.     

En bloc resection of the hip via a simultaneous double approach

The pelvis is not an uncommon localization for primary or secondary tumors. Progress in chemotherapy has reduced the risk of metastasis and advances in reconstruction surgery using prostheses or allografts has made it possible to preserve a functional limb. We describe our method for en bloc resection of the hip. We use a double simultaneous approach for en bloc resection of the hip. The posterior Kocher-Langenbeck approach is associated with a anterior iliocrural approach. Each approach is performed by a separate team. We analyzed the advantages and disadvantages of this method, describing three recent cases. The double-simultaneous approach allowed greater safety for en bloc carcinological resection of the hip for patients with malignant tumors or aggressive intra-articular extension. Reconstruction was achieved with a total hip arthroplasty, reducing the duration of the operation and in theory, blood loss and risk of secondary infection. This method would not be indicated for patients without pelvic involvement nor for patients with a small-sized tumor (<5 cm).     

Minimum 5-Year Results in 96 Consecutive Hips Treated With a Tapered Titanium Stem System

We performed total hip arthroplasty with single titanium stem in 96 consecutive, nonselected hips. All patients, regardless of bone type and shape, neck shaft angulation, or age, received the same implant. Patients were followed for a minimum of 5 years, and an independent radiographer evaluated the hips for ingrowth, subsidence, leg-length discrepancy, and remodeling. The average Harris Hip score was 96 points (range, 73-100 points) at final follow-up. Radiographically, all stems were ingrown. No stem had more than 3 mm of subsidence, and there were no leg-length discrepancies more than 5 mm. We concluded that this titanium stem is a versatile option for total hip arthroplasty in patients with a wide variety of demographic and femur characteristics.     

Persistent infection associated with residual cement after resection arthroplasty of the hip

BACKGROUND: The danger of residual bone cement after resection of infected prosthetic components is controversial. PATIENTS AND METHODS: We analyzed 10 patients with infected total hip prosthesis who had been treated previously with resection arthroplasty and antibiotics and who had persistent infection with residual cement. In 9 patients, surgical debridement with resection of all the PMMA was performed, and adequate intravenous antibiotics were administered. 1 patient refused surgical treatment, but accepted antibiotics. RESULTS: At an average of 4 (1-18) years of follow-up, 8 patients had no signs or symptoms of recurrent infection. 1 severely immunodeficient patient died 2 years after the removal of residual cement, for reasons other than his hip. The patient who refused surgical treatment continues to have an active sinus 4 years after first consultation. INTERPRETATION: Residual cement may be responsible for chronic infection. At resection arthroplasty, as part of the treatment of an infected hip arthroplasty, all devitalized or foreign material must be removed.     

Bipolar hip arthroplasty as a salvage treatment for instability of the hip

BACKGROUND: Recurrent instability of the hip in the absence of an identifiable cause is a challenging problem. It has been proposed that bipolar hip arthroplasty may have a role in the treatment of these complex cases. The purpose of our study was to evaluate the results of bipolar hip arthroplasty for the treatment of recurrent instability of the hip in a series of patients at our institution. METHODS: We reviewed the records of twenty-seven patients who had undergone bipolar hip arthroplasty as a salvage procedure for the treatment of recurrent instability of the hip after total hip replacement. All patients had undergone at least two, and a mean of three, stabilizing operative procedures on the hip prior to the bipolar arthroplasty. The mean duration of follow-up was five years (range, two to twelve years), with no patient lost to follow-up. There were six deaths, of unrelated causes. RESULTS: Bipolar arthroplasty prevented redislocation in twenty-two hips (81 percent). At the time of final follow-up, twenty-five patients (93 percent) had a stable hip. Five patients (19 percent) had had episodes of subluxation or dislocation following the bipolar arthroplasty. Two of these patients had only a single episode of dislocation that was treated successfully by immobilization. Two of the remaining three patients required a reoperation because of the instability. The hip was stabilized with the use of a constrained cup prosthesis in one of these patients, and the other patient eventually required resection arthroplasty. The third patient had continuing instability but improved function and pain relief, and a reoperation was not performed. There were a total of seven reoperations; these included revision because of disassembly of the cup in one hip, revision bipolar arthroplasty because of continuing instability in two, resection arthroplasty because of deep infection in two, revision arthroplasty because of recalcitrant groin pain in one, and revision arthroplasty because of deep infection and superior migration of the implant in one. The Harris hip score improved significantly, from a mean of 24 points (range, 5 to 45 points) preoperatively to a mean of 55 points (range, 35 to 80 points) postoperatively (p < 0.05). CONCLUSIONS: We believe that, despite some potential problems, bipolar hip arthroplasty can have a role in the salvage management of recurrent instability of the hip in patients in whom other stabilization procedures have failed.     

Resection arthroplasty in radiation-induced osteonecrosis of the hip

PurposeThe purpose of this study was to evaluate the choice of appropriate surgical procedure through follow-up of postoperative results in patients with radiation-induced osteonecrosis of the hip.Materials and methodsFrom January 1990 to December 2010, 25 patients underwent surgery for hip osteonecrosis after pelvic irradiation, for a total of 31 cases. The mean patient age was 61.6 years and the mean follow-up period was 60.4 months. There were 28 cases of primary total hip arthroplasty, three cases of primary resection arthroplasty, and six cases of secondary resection arthroplasty after total hip arthroplasty failure. The THA group was classified into two groups according to the period of operation: 1990 ∼ 2000 and 2001 ∼ 2010. THA and resection arthroplasty were compared retrospectively.ResultsIn the 16 cases of primary total hip arthroplasty (1990 ∼ 2000), 8 cases (50%) had a failed acetabular component. In 12 cases of primary total hip arthroplasty (2001 ∼ 2010), two cases (16.7%) had a failed acetabular component and two cases (16.7%) had an infection. Six cases underwent resection arthroplasty after total hip arthroplasty. There were no complications in the nine cases of resection arthroplasty. Seven of the nine cases (77.7%) had pain relief. The mean VAS scores of the resection arthroplasty group were lower than those of the total hip arthroplasty group at the time of the latest follow up (P = 0.04).ConclusionsThe failure rate of total hip arthroplasty used in radiation necrosis has decreased. Therefore, total hip arthroplasty should be the primary surgical method in patients with radiation-induced osteonecrosis of the hip. Resection arthroplasty is limited as first-line therapy due to functional problems. It use should be limited to pain control in low-demand elderly patients.     

Hospitalizations for Total Hip Arthroplasty after Renal Transplantation in the United States

The national incidence of and factors associated with total hip arthroplasty in renal transplant recipients has not been reported. We conducted an historical cohort study of 42096 renal transplant recipients in the United States between 1 July 1994 and 30 June 1998. Primary outcomes were associations with hospitalizations for a primary discharge code of total hip arthroplasty (ICD9 procedure code 81.51x) within 3 years after renal transplant using Cox regression. Renal transplant recipients had a cumulative incidence of total hip arthroplasty of 5.1 episodes/1000 person-years, which is 5-8 times higher than reported in the general population. Avascular necrosis of the hip was the most frequent primary diagnosis associated with total hip arthroplasty in this population (72% of cases). Repeat surgeries were performed in 27% of patients with avascular necrosis, vs. 15% with other diagnoses. Total hip arthroplasty was more frequent in transplant recipients who were older, African American, or who experienced allograft rejection. Mortality after total hip arthroplasty was 0.21% at 30 days and 15% at 3 years, similar to the mortality of all transplant recipients. The most common indication for total hip arthroplasty after renal transplant is avascular necrosis of the hip, in contrast to the general population. Although repeat surgeries are common, total hip arthroplasty is well tolerated and is not associated with increased mortality in this population.     

Treatment of infected hip arthroplasty with antibiotic-impregnated calcium hydroxyapatite

We reviewed the treatment of infected hip arthroplasty with antibiotic-impregnated calcium hydroxyapatite (CHA) ceramic blocks. Seven consecutive patients consisting of 2 men and 5 women with an average age of 65 years were followed up for an average of 5.0 years. All patients received resection arthroplasty and thorough debridement, followed by implantation of antibiotic-impregnated CHA ceramic. Two-stage revision was performed in all patients. There was no evidence of a recurrent infection in 6 patients. The remaining one patient underwent an additional debridement 2 years after the second stage. This patient was free of infection at the time of the latest follow-up. Antibiotic-impregnated CHA ceramic is thus considered to be an excellent drug delivery system for the infected hip arthroplasty.     

Two-stage reconstruction of a total hip arthroplasty because of infection

From 1969 to 1985, eighty-one patients (eighty-two hips) who had an infection after a previous total hip arthroplasty were treated with a resection arthroplasty, followed by delayed reconstruction in the form of a repeat total hip arthroplasty. For all of the reconstructions, the femoral and acetabular components were fixed to bone with cement that did not contain antibiotics. An average of 5.5 years (range, 2.0 to 13.6 years) after reimplantation, infection had recurred in eleven hips (13 per cent). The presence of retained cement at the time of the resection arthroplasty appeared to be associated with recurrent sepsis, as three of seven patients who had retained cement had a recurrent infection, compared with only eight (11 per cent) of seventy-five patients from whom the cement had been completely removed (p less than 0.01). The twenty-six patients (twenty-six hips) who had the reimplantation less than one year after the resection arthroplasty had seven recurrent infections (27 per cent), while the fifty-six patients who had reimplantation more than one year after the resection arthroplasty had only four recurrences (7 per cent) (p less than 0.001). Three of the seven patients in whom the infection was caused by gram-negative bacilli and group-D streptococcal organisms (which are considered highly virulent) and who received systemic antimicrobial therapy for less than twenty-eight days had a recurrence. In contrast, only one of the thirteen patients in whom the infection was caused by a virulent organism and who were treated for longer than twenty-eight days had a recurrence (p = 0.055). The two-stage reconstruction is an effective, safe technique even when the infection is caused by a virulent organism.     

Anaesthesia for patients over 90 years of age. Outcomes after regional and general anaesthetic techniques for two common surgical procedures

Peri-operative morbidity and mortality and long term outcome of patients over 90 years of age who underwent either total hip arthroplasty or transurethral prostate resection were studied retrospectively. The outcomes of patients who received regional or general anaesthesia were compared. One hundred and forty-one patients underwent total hip arthroplasty and 44 patients underwent transurethral prostate resection during the study period (1975-1985). Overall in-hospital mortality was 4.9% Mortality at 30 days was 5.3% in patients who underwent hip arthroplasty during regional anaesthesia, compared with 6.8% in those who received general anaesthesia. Long term survival was similar for these two groups and was longer than projected for age and gender-matched general population cohorts. The 30-day mortality rate was 3.2% for patients who underwent prostatic resection under regional anaesthesia; no deaths occurred in the general anaesthesia group. This difference was not statistically significant. Long term survival was similar for patients in both groups and was better than predicted. Anaesthetic technique did not influence short term morbidity and mortality or long term outcome for these procedures.     

髋关节置换术后早期失败原因的回顾性分析

目的探讨髋关节置换术后早期失败的原因和特点。方法对1995年1月至2009年1月本组收治的342例初次髋关节置换（THA）失败患者进行回顾性分析,将这些失败的患者分为早期失败组（初次髋关节置换术后〈5年内失败组）和晚期失败组（初次髋关节置换术后〉5年失败组）,再对早期失败组患者的翻修原因进行分析。结果以髋关节翻修作为终止点,42．1％（144／342）的患者在初次THA术后5年内进行翻修,在早期失败的两个主要原因中,31．2％是因为无菌性松动,24．3％是因为髋关节脱位。结论THA术后早期的失败原因是无菌性松动和髋关节脱位。外科医师要提高手术技术,以避免THA术后的早期失败。     

Repeat 2-Stage Exchange for Infected Total Hip Arthroplasty : A Viable Option?

We investigated whether performing a repeat 2-stage exchange eradicates infection in patients who previously underwent 2-stage treatment for an infected total hip arthroplasty. We identified 15 patients who had failed a 2-stage total hip arthroplasty and underwent a planned repeat 2-stage between 2000 and 2009. Of the 15 patients, 8 were treated with a complete 2-stage procedure, whereas the remaining 7 patients were treated only with a first-stage resection of the infected implant. Of the 8 patients who underwent complete 2-stage exchange, 1 died because of in-hospital complications, and 1 had a recurrent infection. Repeat infection is highly associated with resistant organisms, obesity, and poor patient health. Of the 7 patients who underwent resection without reimplantation, 3 had a recurrent infection. Our data suggest that if infection can be adequately controlled after repeat resection of the joint prosthesis, reimplantation is a reasonable option.     

Synchronous Periprosthetic Joint Infections: High Mortality,Reinfection, and Reoperation

BackgroundSynchronous periprosthetic joint infections (PJIs) are a catastrophic complication with potentially high mortality. We aimed to report mortality, risk of reinfection, revision, reoperation, and implant survivorship after synchronous PJIs.MethodsWe identified 34 patients treated for PJI in more than one joint within a single 90-day period from 1990 to 2018. PJIs involved bilateral knee arthroplasty (27), bilateral hip arthroplasty (4), 1 knee arthroplasty and 1 elbow arthroplasty (1), 1 knee arthroplasty and 1 shoulder arthroplasty (1), and bilateral hip and knee arthroplasty (1). Irrigation and debridement with component retention was performed in 23 patients, implant resection in 10 patients, and a combination of irrigation and debridement with component retention and implant resection in 1 patient. A competing risk model was used to analyze implant survivorship, and Kaplan-Meier survival was used for patient mortality. Mean follow-up was 6 years.ResultsMortality was high at 18% at 30 days and 27% at 1 year. The 1-year cumulative incidence of any reinfection was 13% and 27% at 5 years. The 1-year cumulative incidence of any revision or implant removal was 6% and 20% at 5 years. The 1-year cumulative incidence of unplanned reoperation was 25% and 35% at 5 years. Rheumatoid arthritis was associated with increased risk of mortality (HR 7, P < .01), as was liver disease (HR 4, P = .02).ConclusionIn the largest series to date, patients with synchronous PJIs had a high 30-day mortality rate of 18%, and one-fourth underwent unplanned reoperation within the first year.     

Repeat 2-stage exchange for infected total hip arthroplasty: a viable option?

We investigated whether performing a repeat 2-stage exchange eradicates infection in patients who previously underwent 2-stage treatment for an infected total hip arthroplasty. We identified 15 patients who had failed a 2-stage total hip arthroplasty and underwent a planned repeat 2-stage between 2000 and 2009. Of the 15 patients, 8 were treated with a complete 2-stage procedure, whereas the remaining 7 patients were treated only with a first-stage resection of the infected implant. Of the 8 patients who underwent complete 2-stage exchange, 1 died because of in-hospital complications, and 1 had a recurrent infection. Repeat infection is highly associated with resistant organisms, obesity, and poor patient health. Of the 7 patients who underwent resection without reimplantation, 3 had a recurrent infection. Our data suggest that if infection can be adequately controlled after repeat resection of the joint prosthesis, reimplantation is a reasonable option.     

Coxarthrosis after traumatic hip dislocation in the adult

Sixteen percent of patients with uncomplicated hip dislocations have posttraumatic arthritis develop. Incidences as high as 88% are reported for patients with dislocations associated with severe acetabular fractures. The surgical treatment of patients with posttraumatic arthritis includes arthroscopy, arthrodesis, osteotomy, and arthroplasty. Although arthroplasty offers the best solution for the painful arthritic hip in the older or inactive patient, the treatment of an active patient in the prime of life with severe osteoarthritis of the hip is problematic. In the younger, active patient, it may be prudent to consider alternative treatment in an attempt to avoid, or delay, total hip arthroplasty. Although improving the longevity of primary arthroplasty is desirable, measures to prevent or delay the onset of the osteoarthritis seem more appropriate. Arthroscopic lavage, debridement and chondral abrasion, and osteochondral fragment removal after dislocation may have a role in the treatment of young patients with the early stages of coxarthrosis. Any patient with isolated posttraumatic arthritis of the hip who has a life expectancy greater than 30 years may be a candidate for hip arthrodesis. The ideal candidates for hip arthrodesis are only laborers younger than 35 years of age. Osteotomy of the hip for posttraumatic arthritis remains an appealing alternative for many patients because of the long-term failures of total hip arthroplasty. The clinical results of osteotomy are variable and do not match the results of a total hip arthroplasty. However, primary arthroplasty may fail, and revision arthroplasty is routinely more difficult and shorter lived than the primary operation.     

Resection arthroplasty of the hip

Forty-four patients with 46 resection arthroplasties performed for various indications were followed an average of 8.0 years. Pain relief was good or excellent in 77% and eradication of infection was achieved in all but one. Completeness of cement removal at the time of resection arthroplasty did not affect the results or control of infection. Patients with a history of prior septic total hip arthroplasty had results similar to those for patients with other indications for resection arthroplasty. A comprehensive review of the literature supports these results.     

Impregnation of vancomycin, gentamicin, and cefotaxime in a cement spacer for two-stage cementless reconstruction in infected total hip arthroplasty

Twenty-two patients with infected total hip arthroplasty were treated with 2-stage arthroplasty, using a cement spacer impregnated with a combination of 3 thermostable antibiotics (vancomycin, gentamicin, and cefotaxime). Initially, implants were removed, and a spacer was inserted. Six to 12 weeks later, the spacer was removed, and the patients underwent reconstruction using cementless components. The patients were followed for an average of 41 months. One patient had a recurrence of infection and was treated with resection arthroplasty. The remaining 21 patients (95%) had no evidence of infection at the final follow-up. We recommend using the combination of these 3 antibiotics in the cement spacer for 2-stage reconstruction in infected hip arthroplasty when the causative organism is not identified in the culture of preoperative aspiration.     

Intrathecal morphine for postoperative analgesia: a randomized, controlled, dose-ranging study after hip and knee arthroplasty

In this series, we examined analgesia and side effects of intrathecal morphine sulfate (ITMS) after hip and knee arthroplasty over a dose range of 0.0-0.3 mg. Eighty patients undergoing hip (n = 40) or knee (n = 40) arthroplasty were randomized to receive ITMS (0.0, 0.1, 0.2, or 0.3 mg). A patient-controlled analgesia (PCA) device provided free access to additional analgesics. Morphine use, pain relief, and side effects were recorded for 24 h. Data were analyzed with analysis of variance and linear regression. After hip arthroplasty, morphine use was less in patients receiving 0.1, 0.2, or 0.3 mg of ITMS than in control patients (P < 0.05). After knee arthroplasty, ITMS did not reduce postoperative morphine requirements. Nausea and vomiting and the incidence of oxygen saturation <93% were similar in all groups. Pruritus was more common after ITMS. Patients receiving 0.2 or 0.3 mg of ITMS were more satisfied with their pain control than those receiving 0.0 or 0.1 mg after both hip and knee arthroplasty. Analgesic needs are greater after knee arthroplasty than after hip arthroplasty. We conclude that combining small-dose (0.2 mg) ITMS with PCA morphine provides good to excellent pain control in most patients after total hip or knee arthroplasty. However, PCA morphine use was reduced by the addition of ITMS only after hip arthroplasty. IMPLICATIONS: This series examined the need for supplemental analgesics, the quality of analgesia, and the incidence of side effects with intrathecal morphine sulfate (ITMS) for analgesia after hip and knee arthroplasty. Analgesic needs are greater after knee arthroplasty than hip arthroplasty. Combining small-dose (0.2 mg) ITMS with standard doses of PCA morphine provided good to excellent pain control in most patients and reduced patient-controlled analgesia morphine use after hip, but not knee, arthroplasty.     

Does Discharge Disposition After Primary Total Joint Arthroplasty Affect Readmission Rates?

We reviewed 90-day readmission rates for 9150 patients with a primary total hip or knee arthroplasty performed between April 2001 and December 2004. Patients with an American Society of Anesthesiologists score of 3 or greater or with perioperative complications were excluded. We correlated the readmission rate with discharge disposition to either skilled nursing facilities (SNFs) or Home. Of the 9150 patients identified, 1447 were discharged to an SNF. After statistically adjusting for sex, age and American Society of Anesthesiologists scores, total hip arthroplasty and total knee arthroplasty patients discharged to SNFs had higher odds of hospital readmission within 90 days of surgery than those discharged home (total hip arthroplasty: odds ratio = 1.9; 95% confidence interval, 1.2-3.2; P = .008; total knee arthroplasty: odds ratio = 1.6; 95% confidence interval, 1.1-2.4; P = .01). Healthy patients discharged to SNFs after primary total joint arthroplasty need to be followed closely for complications.     

A population study in the Province of Ontario of the complications after conversion of hip or knee arthrodesis to total joint replacement.

OBJECTIVE: To evaluate the complication rates after conversion of hip and knee fusions to total joint replacements in the Province of Ontario. DESIGN: A retrospective cohort study. PATIENTS: Those who had undergone an elective conversion of a hip or knee fusion to a total joint replacement during fiscal year 1993 through 1996, as captured in the Canadian Institute for Health Information and Ontario Health Insurance Plan databases. OUTCOME MEASURES: Inhospital complications and length of initial hospital stay, revision, infection, amputation and repeat fusion rates within 4 years. RESULTS: Conversion of hip and knee fusion to total joint arthroplasty was generally performed by high-volume surgeons in high-volume hospital settings. Forty hip and 18 knee replacements involved conversion of a previous fusion. Conversion of a hip fusion was associated with a 10% infection rate, a 10% revision rate and a 5% resection arthroplasty rate due to infection within 4 years of the conversion. Conversion of a knee fusion was associated with an 11% infection rate, and a more than 5% revision rate at 4 years. Over 16% of patients who underwent conversion of a knee fusion required removal of the components (for various reasons) within the first 4 years. CONCLUSIONS: There is a high rate of complications after conversion of a hip or knee fusion to a total joint arthroplasty. These issues must be carefully considered and discussed with the patient before any conversion procedure.