Size of Medial Knee Osteophytes Correlates With Knee Alignment But Not With Coronal Laxity in Patients With Medial Knee Osteoarthritis

The severity of osteoarthritis (OA) has been related to osteophyte size. However, the effects on osteophyte size of repeated and increased loading associated with joint laxity and varus misalignment remain unclear. We investigated these relationships in patients with medial knee OA and compared the performances of computed tomography (CT) and radiography for assessing osteophyte parameters. We examined knee joint alignment on radiographs and knee laxity using arthrometry in 191 patients with medial knee OA who were undergoing total knee arthroplasty. We also measured femur and tibia osteophyte distance (largest perpendicular distance from the cortical line to outer margin of the osteophyte) using radiography and CT, osteophyte areas (largest area surrounded by the outer margin of an osteophyte) by CT and determined the locations of the osteophytes in the femur and tibia by CT. We then analyzed the correlations between the variables using Spearman's rank correlation tests. Osteophyte sizes in the femur and tibia as determined by radiography (distance) or CT (distance and area) were positively correlated with the degree of varus alignment but not with medial or lateral laxity. There was also a significant correlation between maximum osteophyte distances measured by radiography and CT. The greatest number and the largest osteophytes were located in the posterior third of the femur and middle third of the tibia, respectively. Osteophyte size was correlated with preoperative knee alignment but not with knee laxity in patients with medial knee OA. Osteophyte size can be evaluated using conventional radiography, without the need for CT. © 2019 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 38:639–644, 2020     

Posterior clearance increases the knee extension angle in cruciate retaining type total knee arthroplasty: Intraoperative evaluation using a navigation system

BackgroundPosterior osteophyte of the femur can impinge on the tibia insert in total knee arthroplasty (TKA). Although osteophyte removal [posterior clearance (PC)] improves the flexion angle, its influence on the gaps and extension angle are unclear. This study investigated the effect of PC on the gaps and range of motion (ROM) using a navigation system, as well as PC's relationship with osteophyte size.MethodsTwenty-seven knees that underwent cruciate-retaining (CR)-type TKA were examined. Before and after PC, the ROM, hip-knee-ankle (HKA) angle, and flexion and extension gaps were recorded using a navigation system. Osteophyte size was measured in the lateral view in radiographs, and in the sagittal and axial planes of computed tomography (CT) images. The effects of PC on the gaps and ROM were analysed statistically.ResultsPC caused the extension gap to increase by 0.7 ± 0.9 mm in the medial (p < 0.001), and 0.9 ± 1.5 mm in the lateral compartment (p = 0.006). The extension angle increased by 4.9 ± 1.6°, flexion angle increased by 6.5 ± 5.0°, and HKA decreased by 0.3°. The increase in extension angle by PC was significantly correlated with the preoperative HKA angle (r = 0.594) and with the osteophyte area in radiographs and CT (r = 0.626 to 0.681).ConclusionsThe extension and flexion gaps increased less than 1 mm in the medial and lateral compartments. PC achieving an additional 5° extension angle could promote full extension in severely deformed knees with a large posterior osteophyte. The extension angle increase by PC was correlated with the preoperative HKA angle and osteophyte size.     

Unikompartimentelle Oxford-III-Prothese mit mobilem Gleitlager

Objective

Replacement of the joint surfaces in the medial compartment by an endoprothesis with a mobile bearing.

Indications

Unicompartimental anteromedial gonarthrosis with an intact anterior cruciate ligament. Avascular necrosis at the medial femoral condyle.

Contraindications

Third to fourth degree cartilage damage in the lateral compartment. Lateral menisectomy. Symptomatic osteoarthritis in the femoropatellar joint. Chronic polyarthritis. More than 15° varus. Varus passive not redressable. Medial or lateral subluxation. More than 15° extension deficit. Passive flexion less than 110°. Cruciate ligament lesions with instability. Poor soft tissue conditions.

Surgical technique

The leg is mounted on an electric leg holder that allows flexion up to 120°. The joint is opened via an anteromedial arthrotomy starting at the medial border of the patella and ending 3 cm below the tibia plateau. The osteophytes are resected and the tibial resection is performed with an oscillating saw under guidance of a jig which is positioned according to the physiological tibial slope. The medial collateral ligament must be protected with a Hohmann retractor. The vertical cut is performed first; then the horizontal cut is performed. The size of the resected plateau should allow space for a tibial component and a meniscus implant of 4 mm. The resected plateau seves to determine the size of the plateau. The jig for the femoral preparation is adjusted according to the axis of femur and tibia. After the posterior resection the 0 mm spigot is inserted into the central drill hole and the distal part of the condyle is milled. The depth of milling is determined by equalizing the flexion and extension gap. Extension and flexion gap balancing is controlled with test inlays. Posterior osteophytes at the medial femur condyle are cut with a special chisel. In the anterior aspect bone resection is needed to prevent impingement of the meniscus implant. Then the tibia plateau is finally prepared. After inserting the test implants the femoral and tibial components are cemented in one or two stages.

Postoperative management

The patient is mobilised under full weight bearing with two crutches.

Results

A total of 50 Oxford III hemiarthroplasties were implanted using the minimal invasive technique. Indication was an anteromedial gonarthrosis with intakt anterior cruciate ligament. Age varied between 59 and 79 years with a mean of 71 years. Follow-up was 5 years. There were three revisions till final follow-up. Cause was an inlay luxation in one case and in two cases with lateral arthrosis. The average KOOS score was 92.3 points (±?6 points).     

Humeral osteophyte size and clinical outcomes after anatomic total shoulder arthroplasty

BackgroundThe severity of primary glenohumeral osteoarthritis (PGOA) has been associated with advanced radiographic findings including inferior humeral head osteophytes. The primary objective of this study is to analyze for any correlation between the size of the inferior humeral head osteophyte and functional outcomes in patients undergoing anatomic total shoulder arthroplasty (TSA) for PGOA.MethodsA retrospective review of a multi-surgeon database was performed to identify all patients with PGOA from 2015 to 2019 with a minimum of two-year clinical follow-up. Preoperative anteroposterior and Grashey views were used for all included patients to obtain measurements of the inferior humeral osteophyte. Two groups at the extremes of osteophyte width were identified: 1) patients with absent or minimal osteophytes (lowest quartile of width, < 4.9 mm) and those with large osteophytes (highest quartile of width, > 10.1 mm). Change in active range of motion (ROM) from baseline, patient-reported outcomes (PROs), strength and complications were assessed at a minimum of 2 years postoperatively and compared between the two groups.ResultsDemographics were similar for the large osteophyte group (n = 57) and small osteophyte group (n = 56). There was a higher percentage of patients with more significant glenoid deformity in the large osteophyte group compared to the small osteophyte group (P = .009 for A1 deltoid). The large osteophyte group had significantly more restricted preoperative ROM for all measures (P < .05 for all). There were no significant differences in final ROM achieved between the two groups. Patients in the large osteophyte group had greater improvement from baseline for external rotation at the side (31° vs 21°, P = .015), external rotation at 90° abduction (38° vs 20°, P = .004), and internal rotation at 90° abduction (30° vs 12°, P < .001) compared to the small osteophyte group. Overall, there were very few differences between the small and large osteophyte groups in final PROs, with the exception of a higher American Shoulder and Elbow Surgeons score in the large osteophyte group (90.8 vs 85.9, P = .048).ConclusionPatients with large humeral osteophytes have significantly greater restrictions in preoperative ROM compared to patients with small osteophytes. Patients with large osteophytes experience greater improvements in rotational motion after anatomic TSA compared to patients with small osteophytes, although the final ROM achieved was similar between groups. Overall, PROs after anatomic TSA were similar between patients with small and large osteophytes preoperatively.     

Medial epicondyle osteotomy: a method of choice in severe varus knee arthroplasty

The purpose of this study was to evaluate the results of total knee arthroplasty (TKA) after using medial epicondyle osteotomy (MEO) as a balancing method for severe varus deformity and also to compare these results with those of TKA after using additional resection of the tibial medial plateau to correct this deformity. A total of 60 knees with severe varus deformity underwent TKA between 2006 and 2010. In 30 cases, we used MEO as a balancing method, and in other 30, additional medial tibial plateau resection was performed. The clinical outcomes were measured with the Knee Society score (KSS), the range of the motion and frontal laxity of the knee. The radiological outcomes were measured by anteroposterior simple radiographs to assess: the union state of the osteotomy site, the amount of resected tibial medial plateau bone and the femorotibial angle. The findings of the study show that in the MEO group the KSS improved from 21.13?±?13.6 to 92.1?±?7.6 points (P?<?0.001). Moreover, the range of motion increased from 70.3°?±?25.3° to 109.3°?±?12.7° (P?<?0.001). The femorotibial angle was corrected from a 22.6°?±?5.71° varus to a 4.0°?±?1.38° valgus (P?<?0.001) and frontal laxity decreased from 10.83°?±?3.9° to 0.33°?±?1.2° (P?<?0.001). No statistically significant differences were found between groups regarding the postoperative outcomes of KSS, range of motion, femorotibial angle and frontal laxity. The amount of resected tibial medial plateau bone was statistically significantly smaller in the MEO group (1.63?±?0.96?mm in the MEO group and 4.73?±?2.7?mm in the other group; P?<?0.001). In the MEO group, the mean thickness of the polyethylene insert was 12.66?±?1.21?mm, while in the second group, it was 13.73?±?1.59?mm, with statistically significant P?=?0.005. Fibrous union occurred in all knees in the MEO group. Using medial epicondyle osteotomy for varus knee when performing total knee arthroplasty could be a useful ligament-balancing technique to achieve medial stability of the knee. In addition, it could have considerable advantages towards the additional resection of the tibial medial plateau.     

Effects of long-term estrogen replacement therapy on the prevalence and area of periarticular tibial osteophytes in surgically postmenopausal cynomolgus monkeys

Osteoarthritis (OA) occurs naturally in cynomolgus macaques. The purposes of the present study were to: 1) develop histological measurement schemes to measure the cross-sectional area of axial and abaxial osteophytes in the proximal tibia; 2) determine the effects of long-term estrogen replacement therapy (ERT) on osteophyte prevalence and area; and 3) assess relationships between osteophyte size and risk factors of OA (age and body weight) and concurrent bone and cartilage lesions. Adult female cynomolgus macaques (n=180) were bilaterally ovariectomized (OVX) and were treated for 3 years with ERT, soy phytoestrogens (SPE), or no hormones (OVX controls). At necropsy, the prevalence and cross-sectional area of periarticular tibial osteophytes were evaluated histologically. Treatment effects on osteophyte prevalence and area were evaluated using Chi-square analyses and Kruskal-Wallis test, respectively; other comparisons were evaluated using regression analyses. The prevalence of abaxial osteophytes in the medial tibial plateau was not significantly affected by treatment group; however, the prevalence of abaxial osteophytes in the lateral tibial plateau was significantly lower in ERT group than SPE group (p<0.01). The total number of abaxial osteophytes (sum of lateral and medial) was significantly lower in ERT group compared to OVX and SPE groups. Neither the prevalence of axial osteophytes nor the sum of lateral and medial axial osteophytes was significantly affected by treatment in either tibial plateau. There were no significant treatment effects on axial or abaxial osteophyte cross-sectional area in either tibial plateau. There was a significant positive correlation between abaxial osteophyte area and SCB thickness in the medial tibial plateau (p=0.048); however, there were no significant correlations between abaxial osteophyte area (medial or lateral) and age or body weight. In this model of naturally occurring OA, long-term ERT does not consistently reduce the prevalence, and has no significant effects on cross-sectional area, of periarticular tibial osteophytes.     

Adopting the Joint Line Theory for Bone Resection in Cruciate‐Retaining Total Knee Arthroplasty to Prevent Flexion Gap Tightness

BackgroundDuring a conventional measured resection using the posterior reference method for total knee arthroplasty (TKA) in varus knees, proximal tibia is resected from the lateral joint surface for the same thickness as the implant. Distal femur is resected from the worn medial surface for the same thickness as the implant. Posterior femur is resected using the posterior reference method with an external rotation for appropriate degrees. In this situation, although the joint line of the tibia is leveled to the height of lateral joint surface, the posterior joint line of the femur is leveled to the center of medial and lateral posterior condyle, which is a few millimeters lower than the lateral posterior condyle. This discrepancy between the proximal tibia‐posterior femoral joint line causes a tight flexion gap in cruciate‐retaining TKA. Therefore, downsizing of the femur is necessary to adjust the posterior joint line to the level of the lateral condyle.PerspectivesTo avoid this circumstance, the postoperative joint line should be leveled to the center of the original medial and lateral joint surface. Proximal tibia is resected from the lateral joint surface 1 mm to 2 mm thicker than the implant. Distal femur is resected from the worn medial surface 1 mm to 2 mm thinner than the implant. Posterior femur is resected using the posterior reference method with an external rotation for appropriate degrees. In this situation, all the joint lines are leveled to the center of the medial and lateral joint surface. Otherwise, use of an anatomically shaped implant with a physiologic joint line is another option to avoid joint line discrepancy.ConclusionsAdopting joint line theory for bone resection can prevent the flexion gap tightness that likely occurs in cruciate‐retaining TKA.     

Comparison of postoperative alignment using fixed angle versus variable angle distal femoral resection in uncomplicated total knee replacement

Purpose

This study aimed to compare the postoperative alignment of the lower limbs using fixed angle versus variable valgus angle distal femur resection in uncomplicated total knee replacement (TKR) and to determine the mean valgus correction angle (VCA) in the study population.

Methods

This was a prospective comparative study conducted between July 2018 and December 2019 in patients with osteoarthritic knees who underwent primary TKR. Forty-nine patients with 54 knees completed the study. They were randomized into fixed valgus angle (group A) and variable valgus angle (group B) groups. Twenty-four patients with 26 knees were in group A who had distal femur resection with 5-degree valgus correction, while 25 patients with 28 knees were in group B who had distal femur resection with individualized valgus correction angle calculated from hip-knee-ankle scanogram.

Results

The demographic data were comparable in the two groups. There was no statistically significant difference between the groups in the mean preoperative mechanical femorotibial angle (MFTA). The fixed angle group had a mean postoperative MFTA of 2.0 ± 2.8°, while variable angle group had a mean of 1.6 ± 2.4°. However, the difference between the groups did not reach statistical significance (p = 0.60). The mean VCA in the study population was 5.8 ± 1.2° (Range 4–9°).

Conclusion

Our study has shown that the use of variable valgus angle for distal femur resection in uncomplicated TKR did not significantly improve the accuracy of restoring the postoperative coronal alignment within 0 ± 3°.

     

Effects of posterior condylar osteophytes on gap balancing in computer-assisted total knee arthroplasty with posterior cruciate ligament sacrifice

Objective

Gap planning in navigated total knee arthroplasty (TKA) is a critical concern. Osteophytes are normally removed prior to gap planning, with the exception of posterior condylar osteophytes of the femur, which are removed after posterior condylar resection. This study investigated how posterior condylar osteophytes affect gap balancing during surgery.

Methods

This prospective study was conducted on 40 primary varus osteoarthritic knees with a posterior condylar osteophyte that underwent TKA navigation. For all knees, computed tomography (CT) was performed to evaluate osteophyte position. The extension gap and flexion gap were determined under navigation using a tension device with a distraction force of 44 lb. The extension gap and flexion gap were measured before and after osteophyte removal.

Results

This study revealed that the average osteophyte thickness after removal was 7.75 ± 5.34 mm. The average extension gap change was 0.64 ± 0.80 mm, and the average flexion gap change was 0.85 ± 1.12 mm. With respect to increases in the medial extension gap, lateral extension gap, medial flexion gap and lateral flexion gap, the average effects of posterior condylar osteophyte removal were 0.74 ± 0.81 mm, 0.53 ± 0.96 mm, 0.71 ± 0.97 mm and 1.00 ± 1.41 mm, respectively. Posterior condylar osteophyte thickness was also significantly associated with increases in the lateral extension gap (R² = 0.107, p = 0.03), medial flexion gap (R² = 0.101, p = 0.04) and lateral flexion gap (R² = 0.107, p = 0.04).

Conclusion

These results indicated that posterior condylar osteophytes of the femur affect gap balancing during TKA navigation.

     

Total knee replacement in severe genu varum deformity

In patients with osteoarthritis (OA) and severe osseous deformity of the knee, total knee replacement (TKR) is a major challenge. If the preoperative deformity exceeds 15°, restoration of the correct mechanical alignment will be difficult to achieve. In the management of medial compartment OA associated with a deformity of more than 15°, there is no agreement on the policy to adopt. The first step to be taken is a detailed analysis of the deformity, to determine where it is articular (wear, laxity) or extra-articular (constitutional or acquired bony deformity). The options open to the surgeon are: isolated valgus osteotomy (with TKR at a later stage), TKR or one-stage opening-wedge tibial valgus osteotomy and TKR. This chapter examines the different options and describes the authors’ preferred strategy.     

固定平台后稳定型假体全膝关节置换术后的运动学研究

 目的 探讨固定平台后稳定型假体全膝关节置换(total knee arthroplasty,TKA)术后膝关节在负重屈膝下蹲时的运动学特征。方法 选取10名健康志愿者和10例固定平台后稳定型假体TKA术后患者。制作骨骼及膝关节假体三维模型,在持续X线透视下完成负重下蹲动作,膝关节屈曲度每增加15°截取一幅图像。通过荧光透视分析技术完成三维模型与二维图像的匹配,再现股骨与胫骨在屈膝过程中的空间位置,通过连续的图像分析比较正常与固定平台后稳定型假体TKA术后膝关节在负重下蹲时股骨内、外髁前后移动及胫骨内外旋转幅度。结果 负重下蹲时,正常膝关节平均屈曲136°,股骨内、外髁分别后移(7.3±1.2) mm和(19.3±3.1) mm,胫骨平均内旋23.8°±3.4°;TKA术后膝关节平均屈曲125°,股骨内、外髁分别后移(1.4±1.6) mm和(6.4±1.7) mm,胫骨平均内旋8.5°±3.4°。结论 固定平台后稳定型假体TKA术后膝关节运动与正常膝关节相似,均表现出股骨内、外髁后移及胫骨内旋运动,但幅度小于正常膝关节,且在屈膝过程中存在股骨矛盾性前移及胫骨外旋现象。     

Comparing navigation-based in vivo knee kinematics pre- and postoperatively between a cruciate-retaining and a cruciate-substituting implant

Purpose

Individual physiological knee kinematics are highly variable in normal knees and are altered following cruciate-substituting (PS) and cruciate-retaining (CR) total knee arthroplasty (TKA). We wanted to know whether knee kinematics are different choosing two different knee designs, CR and PS TKA, during surgery using computer navigation.

Methods

For this purpose, 60 consecutive TKA were randomised, receiving either CR (37 patients) or PS TKA (23 patients). All patients underwent computer navigation, and kinematics were assessed prior to making any cuts or releases and after implantation. Outcome measures were relative rotation between femur and tibia, measured medial and lateral gaps and medial and lateral condylar lift-off.

Results

We were not able to demonstrate a significant difference in femoral external rotation between either group prior to implantation (7.9° CR vs. 7.4° PS) or after implantation (9.0° CR vs. 11.3° PS), both groups showed femoral roll-back. It significantly increased pre- to postoperatively in PS TKA. In the CR group both gaps increased, the change of the medial gap was significantly attributable to medial release. In the PS group both gaps increased and the change of the medial and of the lateral gap was significant. Condylar lift-off was observed in the CR group during 20° and 60° of flexion.

Conclusion

This study did not reveal significant differences in navigation-based knee kinematics between CR and PS implants. Femoral roll-back was observed in both implant designs, but significantly increased pre- to postoperatively in PS TKA. A slight midflexion instability was observed in CR TKA. Intra-operative computer navigation can measure knee kinematics during surgery before and after TKR implantation and may assist surgeons to optimise knee kinematics or identify abnormal knee kinematics that could be corrected with ligament releases to improve the functional result of a TKR, whether it is a CR or PS design. Our intra-operative finding needs to be confirmed using fluoroscopic or radiographic 3D matching after complete recovery from surgery.     

Importance of the lateral anatomic tibial slope as a guide to the tibial cut in total knee arthroplasty in Japanese patients

Using three-dimensional computed tomography in 50 osteoarthritic knees, we simulated at various cutting angles the tibial cut for total knee arthroplasty. Cutting angles of 0°, 3°, 5°, 7°, 9°, and 11° were used. We then calculated the anterior and posterior thicknesses, the medial-lateral widths, and the medial and lateral condylar depths of the resected tibial bone at each cutting angle. Each set of measurements was evaluated according to a comparison between the cutting angle and the anatomic posterior slopes. The cutting angles showing the smallest anterior-posterior difference at the medial and lateral plateaus were 9° and 7°, respectively. The mean anatomic posterior slopes at the medial and lateral plateaus were 9.0° and 8.1°, respectively. When the tibia was cut at the cutting angle closest to the medial anatomical posterior slope in each knee, the thickness of the lateral posterior plateaus resected from 12 knees (24%) was more than 10mm. Among these 12 knees, the cutting angle was more than 9° in 9 knees (75%). In contrast, when the tibia was cut at the cutting angle closest to the lateral anatomical posterior slope, only one resected medial posterior plateau was more than 10mm. The cutting angle of this case was 7°. Therefore, in consideration of the thickness of bone resection from anatomic posterior slope, we demonstrated the importance of using the lateral anatomic posterior tibial slope as a guide to the tibial cut. There was no significant difference with respect to resected bone morphology at any cutting angle.     

Fixed‐bearing medial unicompartmental knee arthroplasty restores neither the medial pivoting behavior nor the ligament forces of the intact knee in passive flexion

Medial unicompartmental knee arthroplasty (UKA) is an accepted treatment for isolated medial osteoarthritis. However, using an improper thickness for the tibial component may contribute to early failure of the prosthesis or disease progression in the unreplaced lateral compartment. Little is known of the effect of insert thickness on both knee kinematics and ligament forces. Therefore, a computational model of the tibiofemoral joint was used to determine how non‐conforming, fixed bearing medial UKA affects tibiofemoral kinematics, and tension in the medial collateral ligament (MCL) and the anterior cruciate ligament (ACL) during passive knee flexion. Fixed bearing medial UKA could not maintain the medial pivoting that occurred in the intact knee from 0° to 30° of passive flexion. Abnormal anterior–posterior (AP) translations of the femoral condyles relative to the tibia delayed coupled internal tibial rotation, which occurred in the intact knee from 0° to 30° of flexion, but occurred from 30° to 90° of flexion following UKA. Increasing or decreasing tibial insert thickness following medial UKA also failed to restore the medial pivoting behavior of the intact knee despite modulating MCL and ACL forces. Reduced AP constraint in non‐conforming medial UKA relative to the intact knee leads to abnormal condylar translations regardless of insert thickness even with intact cruciate and collateral ligaments. This finding suggests that the conformity of the medial compartment as driven by the medial meniscus and articular morphology plays an important role in controlling AP condylar translations in the intact tibiofemoral joint during passive flexion. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 36:1868–1875, 2018.

     

Version of the osteoarthritic knee

Version of normal and osteoarthritic knees is evaluated by computed tomography in this study. Version of the knee is defined as the static rotation of the tibia with respect to the femur in full knee extension. It is measured as the difference between the transverse axes of the femoral condyles and tibia. The average knee version, or external rotation of the tibia with respect to the femur across the normal knee, was 0°. Version of the osteoarthritic knee was 5°. Rotation of the tibia with respect to the femur across the extended osteoarthritic knee is a relationship that will affect the placement of components in total knee arthroplasty. This relationship should be addressed in alignment instrumentation and technique to avoid component malalignment in total knee arthroplasty.     

X-ray knee as a screening tool for osteoporosis

Cortical thickness (Cor-Th) of tibia varies considerably on X-ray knees. It was hypothesized that Cor-Th can be used for preliminary prediction of BMD. Ninety nine patients underwent a digital X-ray left knee fixed flexion PA view with an external calibration scale attached to X-ray plate and BMD by DXA using GE lunar machine (Madison, Wisconsin.). Cor-Th was measured at 5 selected levels (A,B,C,D, and E) ranging from 5-7 cm below the tibial plateau on its medial aspect. T-scores were recorded for BMD at AP spine, left forearm and left femur. Cor-Th of tibia at each level significantly correlated with each site of BMD measurement namely AP spine, left femur and left forearm. This correlation varied in the range from 0.241 to 0.426. For AP spine, it was maximum at level C (r=0.347, p<0.001) whereas for left femur and forearm sites, it was maximum at level B (r=0.426 &r=0.373 respectively, p<0.001). The correlation of Cor-Th with BMD varied with age. Above 56 years of age, Cor-Th at each level significantly correlated to BMD at each site. Medial tibial cortical thickness, 6 cm (level C) below tibial plateau can be used as preliminary predictor of patients who need a DXA scan.     

Association between bone mineral density distribution and various radiographic parameters in patients with advanced medial osteoarthritis of the knee

PurposePatients with severe osteoarthritis (OA) of the knee have changes in bone mineral density (BMD) of the distal femur and proximal tibia. Correlations between the medial-to-lateral BMD (M/L-BMD) ratio (which normalizes the potentially confounding effects of body size and sex on BMD) and radiographic parameters that indicate OA progression have not been adequately studied. The purpose of this study was to evaluate correlations between radiographic indicators of OA progression and femoral and tibial M/L-BMD ratios.MethodsA consecutive series of 182 knees in 156 patients with advanced medial knee OA who underwent total knee arthroplasty were included. We evaluated correlations between the femoral and tibial M/L-BMD ratios and various radiographic parameters, including tibiofemoral angle (TFA), mechanical axis angle (MAA), tibial coronal angle, tibiofemoral subluxation (%), load-bearing axis deviation at the tibial plateau (%), and medial and lateral laxity.ResultsUnivariate analyses using Spearman's correlation coefficient revealed significant positive correlations between femoral and tibial M/L-BMD ratios and both TFA and MAA and negative correlations with tibial coronal angle and load-bearing axis deviation. Multivariate analyses showed significant associations between TFA and the femoral M/L-BMD ratio (β = 0.434, p < 0.001) and between MAA and the tibial M/L-BMD ratio (β = 0.384, p < 0.001).ConclusionBMD distribution around the knee might be predictable with radiographic parameters such as the TFA for the femur and MAA for the tibia. The findings of this study provide in vivo data on the evaluation of preoperative femoral and tibial M/L-BMD ratios without dual-energy X-ray absorptiometry.     

Changes in ligamentous laxity after posterior stabilized total knee replacement and factors correlated with postoperative laxity

Instruction

Total knee arthroplasty (TKA) performed with the gap technique can achieve rectangular gaps during flexion and extension by proper bone resection and subsequent soft tissue release. Acquisition of appropriate soft tissue balance is important for successful TKA. It is unknown, however, whether the intraoperative well-balanced ligamentous laxity changes postoperatively over time. We hypothesized that even if good soft tissue balance was achieved intraoperatively the lateral ligamentous laxity would increase with time postoperatively. This phenomenon depends on preoperative background factors.

Methods

We used the angle between the component surfaces of the tibia and femur to define ligamentous laxity. Changes in ligamentous laxity after posterior stabilized minimally invasive surgery (MIS)-TKA were analyzed retrospectively in 150 knees based on radiographic measurements. At 12 months after the operation, the cases were divided into two groups in which the lateral ligamentous laxity in flexion was either ≤3° (balanced group) or >3° (unbalanced group). Factors with a potential to encourage postoperative ligamentous laxity were analyzed.

Results

Our data show that the postoperative ligamentous laxity in extension did not change, whereas the lateral ligamentous laxity in flexion increased with time. This change was significantly related to the preoperative lateral ligamentous laxity, body weight, body mass index, and age.

Conclusion

The results of this study should be taken into account by surgeons performing MIS-TKA with the gap technique.     

Longitudinal study of magnetic resonance imaging and standard X-rays to assess disease progression in osteoarthritis

OBJECTIVE: To investigate, over 1-year, the relationship between X-ray and magnetic resonance imaging (MRI) findings in patients with knee osteoarthritis (OA). METHODS: Sixty-two osteoarthritic patients (46 women) were followed for 1 year. At baseline and after 1 year, volume and thickness of cartilage of the medial tibia, the lateral tibia and the femur were assessed by MRI. A global score from the multi-feature whole-organ MRI scoring system (WORMS) was calculated for each patient at baseline and after 1 year. This score combined individual scores for articular cartilage, osteophytes, bone marrow abnormality, subchondral cysts and bone attrition in 14 locations. It also incorporated scores for the medial and lateral menisci, anterior and posterior cruciate ligaments, medial and lateral collateral ligaments and synovial distension. Lateral and medial femoro-tibial joint space width (JSW) measurements, performed by digital image analysis, were assessed from fixed-flexion, postero-anterior knee radiographs. RESULTS: One-year changes in medial femoro-tibial JSW reach 6.7 (20.5) % and changes in medial cartilage volume and thickness reach 0.4 (16.7) % and 2.1 (11.3) %, respectively. Medial femoro-tibial joint space narrowing (JSN) after 1 year, assessed by radiography, was significantly correlated with a loss of medial tibial cartilage volume (r=0.25, P=0.046) and medial tibial cartilage thickness (r=0.28, P=0.025), over the same period. We found also a significant correlation between the progression of the WORMS and radiographic medial JSN over 1 year (r=-0.35, P=0.006). All these results remained statistically significant after adjusting for age, sex and body mass index. CONCLUSION: This study shows a moderate but significant association between changes in JSW and changes in cartilage volume or thickness in knee joint of osteoarthritic patients.     

Influence of increasing construct constraint in the presence of posterolateral deficiency at knee replacement: A biomechanical study

When faced with posterolateral corner (PLC) deficiency, surgeons must choose a total knee replacement (TKR) construct that provides the appropriate level of constraint. This should match the internal constraint of the device to the soft tissue host laxity pattern. Little guidance is available peroperatively, with factors influencing final component choice remaining ill defined. This study aimed to quantify the effect of PLC insufficiency on the “envelope of laxity” (EoL) after TKR and the effect of increasingly component constraint upon knee behavior through a functional arc of flexion. Using computer navigation, mixed effect modeling and loaded cadaveric legs—laxity was quantified under separate states: the native knee, after implantation of a posterior stabilized (PS)‐TKR, after sectioning the lateral (fibular) collateral ligament and popliteus tendon (PS‐TKR‐PLC), and after re‐implantation with a semi‐constrained “total stabilized” knee replacement (TS‐TKR). Laxity was quantified from 0 to 110° of flexion for anterior draw, varus–valgus, and internal–external rotation. Implantation of the PS‐TKR was consistently associated with increased constraint when compared to the native knee. PLC sectioning led to significantly increased laxity during varus stress from mid to deep flexion. Revision to a TS‐TKR construct restored constraint mimicking that of the primary state but only for the arc of motion 0–90°. In a posterolateral deficient state, a fixed bearing semi‐constrained TS‐TKR restored the knee to near normal kinematics but this was only achieved from an arc of motion 0–90° of flexion. At higher flexion angles, there remained an unfavorable laxity pattern with varus stress opening. © 2015 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:427–434, 2016.