杆卡式固位种植覆盖义齿在严重吸收上颌骨的临床应用

目的：评价Branemmk杆卡式固位种植覆盖义齿修复严重吸收上颌骨全牙列缺失的临床效果。方法：采用Branemark种植系统的常规操作方法，46枚Brdnemark种植体植入11例严重吸收上颌全牙列缺失的患者，3～6个月后，进行Ⅱ期手术，将愈合基台连接在种植体上修复期在Ⅱ期手术二周后进行，选择永久基台连接在种植体上.采用杆卡附着体（Bar-elip attachment），按常规制作和载上塑料活动修复体。结果：Btanemark杆卡式固住种植覆盖义齿修复严重吸收上颌骨全牙列缺失的近期成功率为100％.结论：Barnnemark杆卡式固位种植覆盖义齿修复严重吸收上颌骨全牙列缺失具有良好的临床效果.     

Brnemark种植义齿修复上颌全牙列缺失的临床评价

目的 :评价Branemark种植义齿修复上颌全牙列缺失3年后的临床效果。方法 :采用Branemark种植系统的常规操作方法 ,在I期手术 ,116枚Branemark种植体植入上颌全牙列缺失的16例患者,6个月后 ,进行II期手术 ,再经1周后 ,用固定可卸式修复体修复。结果 :Branemark种植体修复后3年 ,上颌累积成功率为91.1% ,修复体的稳定率为100%。结论 :Branemark种植义齿修复上颌全牙列缺失具有良好的临床效果。     

Branemark种植义齿修复上颌全牙列缺失的临床评价

目的：评价 Branemark种植义齿修复上颌全牙列缺失 3年后的临床效果。方法：采用 Branemark种植系统的常规操作方法，在 I期手术， 116枚 Branemark种植体植入上颌全牙列缺失的 16例患者 , 6个月后，进行 II期手术，再经 1周后，用固定可卸式修复体修复。结果： Branemark种植体修复后 3年，上颌累积成功率为 91.1％，修复体的稳定率为 100％。结论： Branemark种植义齿修复上颌全牙列缺失具有良好的临床效果。     

种植体支持球帽附着体固位下颌覆盖总义齿的临床应用

目的：探讨球帽附着体固位的下颌种植覆盖总义齿的临床效果。方法：随机选择18例下颌牙列缺失的患者,植入2颗种植体,利用球帽附着体固位制作的覆盖义齿,随访6个月—4年,从患者主观感受和X射线检查两方面观察修复效果。结果：覆盖义齿的美观、舒适、固位稳定性好,咀嚼效率高。结论：种植体支持球帽附着体固位的下颌覆盖义齿修复下颌牙列缺失患者临床效果好。     

上下颌游离缺失Brnemark种植义齿早期临床效果的比较研究

目的:比较上下颌游离缺失Branemark种植义齿修复早期临床效果。方法 :5例上颌 (17颗 )和7例下颌(22颗 )游离缺失Branemark种植体植入金合金烤瓷桥修复行使功能18个月后 ,比较上下颌游离缺失Branemark种植体支持固定桥义齿的稳固情况、种植体周牙龈指数和种植体周骨吸收量。结果 :上下颌游离缺失Branemark种植体支持固定桥义齿种植体周骨吸收量无显著性差异 (P>0.05) ;两者种植体周牙龈均处于正常状态 ;上下颌游离缺失种植义齿均未见种植体松动或脱落 ,基台和全冠的稳固性均良好。结论 :上下颌游离缺失Branemark种植体支持种植固定桥义齿修复效果良好     

上/下全牙列缺失的即刻修复和即刻负重的近期疗效观察

目的:本文旨在报告作者对上下颌全牙列缺失采用Diem系统行即刻修复和即刻负重6-9月后的临床经验和临床结果.材料和方法:本组病例共7例,其中女性一例,男6例,平均年龄55.97±7.25SD岁,共植入51颗肩台转换种植体;2例13颗植入上颌.7例共38颗植入下颌,其中2例为全12牙缺失.在植入种植体的当天安装Diem标准IOL基台,完成修复体均采用螺丝目位.永久修复在6-8周完成,观察时间6-9月.结果:一颗植体在三月时松动拔除(1.9%).其余肩台转换种植体骨吸收均小于0.6mrm结论:本组病例在随访期间CSR为98.1%,采用Diem的IOL基台的上下颌全牙列缺失的即刻修复和即刻负重是可靠和有效的.     

杆卡和球帽附着体下颌种植覆盖义齿放射学对比研究

目的：了解杆卡和球帽附着体下颌种植覆盖义齿修复后种植体周齿槽骨的变化。方法：同顾性分析42例全颌牙缺失病例在下颌区各植入2颗种植体,行种植体支持覆盖义齿修复的病例,其中杆卡下颌种植覆盖总义齿19例,球帽式下颌覆盖总义齿23例。对其定期进行随访及放射学检查获得的数据进行总结。结果：杆卡和球帽附着体下颌种植覆盖义齿修复后2年,种植基牙周齿槽骨吸收情况经统计学处理没有差别。结论：杆卡和球帽附着体下颌种植覆盖义齿修复后,短期对种植体基牙周齿槽骨影响没有明显差别。     

Brnemark种植系统在下颌全牙列缺失的临床应用

238颗Branemark种植体植入48名下颌全牙列缺失患者的颌骨内 ,完成固定可卸式修复体46件 ,临床观察30～48个月 ,修复后2年累积成功率为97.4% ,修复体稳定率为100% ,种植失败多数发生在种植早期 ,其主要原因为骨质疏松。     

种植体支持套筒冠固位全口覆盖义齿即刻负重3例

对3例全口无牙颌或重度慢性牙周炎牙列缺损患者术前制作全口义齿或即刻全口义齿,拔除全口余留牙,在下颌植入4颗Ankylos种植体,上颌植入6颗种植体,将SynCone套筒基台接入种植体,再套入预成圆锥形外冠,完成临时义齿修复。3～12个月后将临时义齿更换为铸造支架覆盖义齿。随访12～24个月,除1例种植体在植入后1个月松动拔除而重新植入种植体外,其余种植体均未出现明显的牙槽骨吸收。     

球帽附着体种植覆盖义齿修复牙槽嵴重度萎缩无牙下颌

目的：总结分析BEGO种植体系统球帽附着体固位覆盖义齿,修复重度牙槽骨萎缩无牙下颌的临床应用与效果。方法：对重度牙槽骨萎缩、普通义齿固位极度不良的7例下颌无牙颌患者,在下颌骨前牙区植入2-3枚BEG0柱形螺旋种植体,共植入种植体17枚,后期采用球基台作球帽附着体固位覆盖义齿修复,定期复诊观察评价种植和覆盖义齿修复效果。结果：全部17枚种植体均顺利一期愈合,愈合周期平均3个月,球帽附着体覆盖义齿修复后经6-12个月观察,义齿稳定、咀嚼功能恢复理想,容貌改善明显,患者满意。结论：种植体支持球帽附着体固位覆盖义齿修复牙槽骨重度萎缩无牙下颌,可有效恢复咀嚼功能,改善患者容貌,提高患者生活质量,同时球帽附着体修复,简单经济,易于保持口腔清洁,可以推广。     

柠檬精油对牙周致病菌抑制作用及其安全性初步研究

目的:探讨柠檬精油对牙周致病菌的体外抗菌活性及对细胞增殖的影响。方法:采用微量液体稀释法测定柠檬精油对Pg、Fn、Aa、Pi的最小抑菌浓度(minimal inhibitory concentration,MIC)及最小杀菌浓度(minimum bactericidal concentration,MBC);以较低浓度的MIC为标准稀释LEO作为实验组,采用MTT法测定柠檬精油对HUVECs的毒性作用,明确抑菌浓度下LEO的安全性。结果:柠檬精油对牙周主要致病菌均有抑菌作用,Pg、Fn、Aa、Pi的MIC分别是9.0 g/L、4.5 g/L、4.5 g/L、9.0 g/L,Aa、Fn的 MBC是9.0 g/L,Pg、Pi的MBC未测得。1/2MIC、1/20MIC浓度的LEO能够抑制人脐静脉内皮细胞的生长,而低于1/200MIC浓度的LEO则对人脐静脉内皮细胞的生长没有影响,其中1/200MIC浓度的LEO作用明显优于0.02%的CHX。结论:体外环境中,柠檬精油对牙周致病菌Pg、Fn、Aa、Pi具有抗菌活性,低浓度应用对机体相对安全。     

Oral cancer: molecular technologies for risk assessment and diagnosis

Purpose: The effective biomarkers related to diagnosis, metastasis, drug resistance and irradiation sensitivity of oral cancers will help the pathologist and oncologist to determine the molecular taxonomy diagnosis and design the individualization treatment for the patients with oral cancers.     

Stimulated whole saliva components in children with Down syndrome

The authors report on the components of stimulated whole saliva from children with Down syndrome—including pH, flow rate, sialic acid and protein concentrations, and amylase and peroxidase activity. Saliva samples were collected from 35 children aged 6–10 years. Of the participants, 17 had Down syndrome and 18 did not. To stimulate saliva production, the children chewed a piece of parafilm for 10 minutes before the sample was collected. Soon after collecting the saliva sample, the authors measured pH using a portable pH-meter. Sialic acid levels were determined with a thiobarbituric acid assay. Protein content was determined with Folin's phenol reagent. Amylase was assayed and the authors measured the maltose produced by the breakdown of starch and peroxidase using ortho-dianisidine.
No statistically significant difference was observed in levels of sialic acid (free and total) between the two groups. Protein concentration was about 36% higher in the group with Down syndrome. However, the salivary flow rate, pH, and amylase and peroxidase activities were lower among the children with Down syndrome.     

Computer-assisted planning for maxillofacial prosthodontic rehabilitation

Computerized tomography (CT) planning and the use of CT derived surgical templates for implant placement have shown promise for restoring function within months after surgical reconstruction of acquired post-oncologic defects.     

Effect of Pingyangmycin on human venous malformation endothelial cells

Purpose: Venous malformations are common vascular anomalies with a propensity of the head and neck. Intralesional injection of Pingyangmycin (PYM, bleomycin A5 hydrochloride) is a widely used sclerotherapy method for the treatment of venous malformation.     

牙髓再生的研究现状

目前,根管治疗术在临床上已得到了广泛的应用并成功的保存了患牙,但其仍有许多术后并发症。随着组织工程技术在口腔领域的应用,构建一种组织工程化牙髓进行牙髓-牙本质复合体的再生治疗成为可能。近年来国内外已有很多关于牙髓再生的研究,并且已经取得了一定成果。本文将对目前国内外牙髓再生的研究进展现状作一综述。     

Oropharyngeal dysphagia in amyotrophic lateral sclerosis alters quality of life

Dysphagia is one of the most important complications encountered in amyotrophic lateral sclerosis (ALS). Our aim was to determine whether oropharyngeal dysphagia impacted the quality of life (QoL) of patients with ALS. Thirty consecutive patients were recruited (31–82 years, 18 men). Swallowing function was evaluated using a standardised videofluoroscopic barium swallow. All the patients completed a specific questionnaire on quality of life in dysphagia (SWAL‐QoL) immediately after the videofluoroscopy. The results of dysphagia outcome severity scale separated 14 patients with oropharyngeal dysphagia and 16 with normal swallowing function. There was no difference in the average age, weight and body mass index of the two groups (dysphagic patients: 68 ± 11 kg versus non‐dysphagic patients: 69 ± 14 kg). Most of the dysphagic patients had a bulbar affection based on their Norris scores which determine the importance of cranial nerves illness (20 ± 8), significantly lower than those of the non‐dysphagic patients (35 ± 5) (P < 0·0001). There was no difference in the neurological peripheral symptoms evaluated by Amyotrophic Lateral Sclerosis Functional Rating Scale scores (dysphagic patients: 26 ± 7 versus non‐dysphagic patients: 27 ± 8) (ns). The swallowing quality of life questionnaire revealed that the dysphagic patients had significant burden (P < 0·001). They were affected by the necessity to applied a food selection (P < 0·01), by the increase in eating duration (P < 0·05) and described a decrease in eating desire (P < 0·05). They complained of fear regarding the risk of dysphagia (P < 0·05). They also described difficulties with oral communication (P < 0·001). All of those complained about dysphagia which impacted directly mental health (P < 0·05) and social life (P < 0·05). In conclusion, oropharyngeal dysphagia is a common symptom accompanying ALS, which alters the patient's QoL, especially social health.     

拔牙位点保存用复合温敏凝胶的构建及体外表征

目的:制备多壁碳纳米管/羟基磷灰石/壳聚糖复合温敏凝胶,探讨其作为拔牙位点保存材料的理化性能。方法:采用原位沉积方法制备多壁碳纳米管/羟基磷灰石(MWNT/ HA简称HAC)复合无机材料,将其分散至壳聚糖温敏凝胶中,制备壳聚糖/多壁碳纳米管/羟基磷灰石(CS /MWNT/HA简称CS/HAC)复合温敏凝胶,以成胶时间、孔径、孔隙率、机械强度及降解性能为指标优化配方设计,并表征复合温敏凝胶的微观形貌及理化性能。结果:以10 g/L的HAC作为补强成分加入到壳聚糖溶液中,能够在不影响成胶并保证一定孔隙率(84%)的前提下,提高材料的机械性能(抗压强度0.441 MPa),所获复合温敏凝胶具有适宜的临床操作时间(12 min),并具有可控的降解速率。结论:负载HAC的复合温敏凝胶具有良好的成型性,并具有较好的机械性能,在拔牙位点保存领域具有良好的应用前景。     

Interventional neuroradiologic procedures in the head and neck

Interventional radiology and interventional neuroradiology are evolving specialties which can aid the head and neck surgeons in the clinical management of patients with complex vascular lesions.