Patellofemoral kinematics during knee flexion-extension: an in vitro study.

The purpose of this work was to obtain kinematics data for the normal human patellofemoral joint in vitro. Eight fresh-frozen cadaver knees were used. The heads of the quadriceps were separated, and the knees mounted in a kinematics rig. The femoral axis was aligned with an electromagnetic transmitter. The six heads of the quadriceps, including vasti medialis and lateralis obliquus, were loaded via cables according to their physiological cross-sectional areas and orientations. Magnetic trackers were mounted on the patella and tibia. The knee was flexed-extended against the extending muscle action, and patellar tracking was measured in six degrees of freedom. As the knee flexed, the patella flexed by 0.7 times the tibiofemoral flexion angle. It also translated medially 4 mm to engage the trochlear groove at 20 degrees knee flexion, then translated to 7 mm lateral by 90 degrees knee flexion. The patella tilted progressively to 7 degrees lateral by 90 degrees knee flexion, and patellar medial-lateral rotation was usually less than 3 degrees. This is believed to be the first set of patellar tracking data obtained in both flexion and extension motion while the patella was acted on by a full set of quadriceps muscle tensions acting in physiological directions. These data may be used in future studies of the effects of pathologies on patellar tracking.     

Sectioning the medial patellofemoral ligament alters patellofemoral joint kinematics and contact mechanics

Medial patellofemoral ligament (MPFL) disruption may alter patellofemoral joint (PFJ) kinematics and contact mechanics, potentially causing pain and joint degeneration. In this controlled laboratory study, we investigated the hypothesis that MPFL transection would change patellar tracking and PFJ contact pressures and increase the distance between the attachment points of the MPFL. Eight fresh frozen dissected cadaveric knees were mounted in a rig with the quadriceps and ITB loaded to 205 N. An optical tracking system measured joint kinematics, and pressure sensitive film between the patella and trochlea measured PFJ contact pressures. Length patterns of the distance between the femoral and patellar attachments of the MPFL were measured using a suture led to a linear displacement transducer. Measurements were repeated with the MPFL intact and following MPFL transection. A significant increase in the distance between the patellar and femoral MPFL attachment points was noted following transection (p < 0.05). MPFL transection resulted in significantly increased lateral translation and lateral tilt of the patella in early flexion (p < 0.05). Peak and mean medial PFJ contact pressures were significantly reduced and peak lateral contact pressures significantly elevated in early knee flexion following MPFL transection (p < 0.05). MPFL transection resulted in significant alterations to PFJ tracking and contact pressures, which may affect articular cartilage health. © 2013 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 31:1423–1429, 2013     

Correction of Patellofemoral Malalignment With Patellofemoral Arthroplasty

Background

The goal of patellofemoral arthroplasty (PFA) is to replace damaged cartilage and correct underlying deformities to reduce pain and prevent maltracking. We aimed to determine how PFA modifies patellar height, tilt, and tibial tuberosity-trochlear groove (TT-TG) distance. The hypothesis was that PFA would correct trochlear dysplasia or extensor mechanism malalignment.

Association between measures of trochlear morphology and structural features of patellofemoral joint osteoarthritis on MRI: The MOST study

The sulcus angle has been widely used in the literature as a measure of trochlear morphology. Recently, lateral trochlear inclination and trochlear angle have been reported as alternatives. The purpose of this study was to determine the association between measures of trochlear morphology and patellofemoral joint (PFJ) cartilage damage and bone marrow lesions (BMLs). Nine hundred seven knees were selected from the Multicenter Osteoarthritis Study, a cohort study of persons aged 50–79 years with or at risk for knee OA. Trochlear morphology was measured using lateral trochlear inclination, trochlear angle, and sulcus angle on axial MRI images; cartilage damage and BMLs were graded on MRI. We determined the association between quartiles of each trochlear morphology variable with the presence or absence of cartilage damage and BMLs in the PFJ using logistic regression. The strongest associations were seen with lateral trochlear inclination and lateral PFJ cartilage damage and BMLs, with knees in the lowest quartile (flattened lateral trochlea) having more than two times the odds of lateral cartilage damage and BMLs compared to those in the highest quartile (p < 0.0001). Lateral trochlear inclination may be the best method for assessment of trochlear morphology as it was strongly association with structural damage in the PFJ. © 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 30:1–8, 2012     

Simulation of patella alta and the implications for in vitro patellar tracking in the ovine stifle joint

Patella alta is associated with adverse cartilage adaptations, patellofemoral pain, and instability. It is defined by a relatively long patellar tendon and patella positioned in a more proximal location within the patellar groove of the femur. This study used the ovine stifle joint model to investigate the effect of patellar tendon lengthening on the 3D passive kinematics of the patellofemoral and tibiofemoral joints. Eight patellar tendons were lengthened in 2 mm increments up to a maximum of 12 mm (20%) using a device placed in series with the transected patellar tendon. Three‐dimensional kinematics were measured in the intact joint and at each increment of patellar tendon length (L_T) during passively induced tibiofemoral flexion. Patellar flexion angle was linearly correlated with tibial flexion angle in the intact joint, and this correlation persisted after tendon lengthening (R = 0.897–0.965, p < 0.01). Patellofemoral kinematics expressed as a function of tibial flexion angle were significantly altered by L_T increases >9%. In contrast, when patellofemoral kinematics were expressed as a function of patellar flexion angle they were not significantly altered by increases in L_T. Tibiofemoral kinematics were not affected by the L_T increases. These results demonstrate that for a given tibial flexion angle, patellar tendon lengthening alters the patellar flexion angle. However, for a given patellar flexion angle, the orientation of the patella in the remaining five degrees of freedom is unchanged, implying a repeatable path of patellar motion. © 2012 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 30:1789–1797, 2012     

Three‐dimensional patellar motion at the natural knee during passive flexion/extension. An in vitro study

Patellar maltracking may result in many patellofemoral joint (PFJ) disorders in the natural and replaced knee. The literature providing quantitative reference for normal PFJ kinematics according to which patellar maltracking could be identified is still limited. The aim of this study was to measure in vitro accurately all six‐degrees‐of‐freedom of patellar motion with respect to the femur and tibia on 20 normal specimens. A state‐of‐the‐art knee navigation system, suitably adapted for this study aim, was used. Anatomical reference frames were defined for the femur, tibia, and patella according to international recommendations. PFJ flexion, tilt, rotation, and translations were calculated in addition to standard tibiofemoral joint (TFJ) kinematics. All motion patterns were found to be generally repeatable intra‐/interspecimens. PFJ flexion was 62% of the corresponding TFJ flexion range; tilt and translations along femoral mediolateral and tibial proximodistal axes during TFJ flexion were found with medial, lateral, and distal trends and within 12°, 6 and 9 mm, respectively. No clear pattern for PFJ rotation was observed. These results concur with comparable reports from the literature and contribute to the controversial knowledge on normal PFJ kinematics. Their consistence provides fundamental information to understand orthopedic treatment of the knee and for possible relevant measurements intraoperatively. © 2009 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 27:1426–1431, 2009     

Differences in patellofemoral kinematics between weight‐bearing and non‐weight‐bearing conditions in patients with patellofemoral pain

Patellar maltracking is thought to be one source of patellofemoral pain. Measurements of patellar tracking are frequently obtained during non‐weight‐bearing knee extension; however, pain typically arises during highly loaded activities, such as squatting, stair climbing, and running. It is unclear whether patellofemoral joint kinematics during lightly loaded tasks replicate patellofemoral joint motion during weight‐bearing activities. The purpose of this study was to: evaluate differences between upright, weight‐bearing and supine, non‐weight‐bearing joint kinematics in patients with patellofemoral pain; and evaluate whether the kinematics in subjects with maltracking respond differently to weight‐bearing than those in nonmaltrackers. We used real‐time magnetic resonance imaging to visualize the patellofemoral joint during dynamic knee extension from 30° to 0° of knee flexion during two conditions: upright, weight‐bearing and supine, non‐weight‐bearing. We compared patellofemoral kinematics measured from the images. The patella translated more laterally during the supine task compared to the weight‐bearing task for knee flexion angles between 0° and 5° (p = 0.001). The kinematics of the maltrackers responded differently to joint loading than those of the non‐maltrackers. In subjects with excessive lateral patellar translation, the patella translated more laterally during upright, weight‐bearing knee extension for knee flexion angles between 25° and 30° (p = 0.001). However, in subjects with normal patellar translation, the patella translated more laterally during supine, non‐weight‐bearing knee extension near full extension (p = 0.001). These results suggest that patellofemoral kinematics measured during supine, unloaded tasks do not accurately represent the joint motion during weight‐bearing activities. © 2010 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 29:312–317, 2011     

Influence of Patellar Morphology Classified by Wiberg Classification on Knee Joint Function and Patellofemoral Tracking After Total Knee Arthroplasty Without Patellar Resurfacing

BackgroundTo evaluate the influence of patellar morphology on knee joint function and patellofemoral tracking in patients with primary osteoarthritis after total knee arthroplasty (TKA) without patellar resurfacing.MethodsWe performed a retrospective study of 156 patients with primary osteoarthritis who underwent TKA without patellar resurfacing from April 2018 to July 2019. As per Wiberg classification, patients were divided into Wiberg type I (group A, n = 38), II (group B, n = 88), and III (group C, n = 30) groups. The clinical data, postoperative follow-up data, and radiological data between three groups were compared.ResultsThere was no statistically significant difference in the HSS score and Feller score between the three groups before surgery and at each follow-up point after surgery (P > .05). At the last follow-up, there were no significant differences in the height and relative thickness of the patella between the three groups (P > .05). However, the incidence of anterior knee pain was significantly higher in group C than in the group B (P < .05). The patellar tilt angle was significantly larger in group C than in the groups A and B (both P < .05). The patellar facet angle was significantly larger in group A than in group B and C, which was also significantly larger in group B than in group C (both P < .05).ConclusionPatients with three different morphologic types of the patella both exhibited improved knee joint function after TKA, however, patients with Wiberg type Ⅲ patella were more prone to have poor patellofemoral tracking and anterior knee pain after surgery.     

Patellofemoral function after total knee arthroplasty: gender-related differences

The purpose of the study was to evaluate patellofemoral results in 2 comparable groups of 50 patients, men and women, undergoing total knee arthroplasty. The average follow-up was 6 years. The implant was posteriorly stabilized with a dome patellar arthroplasty. The patients were studied using Knee Society knee and functional scores and the Hospital for Special Surgery (HSS) patellar score. Radiologic study included standard and weight-bearing axial views and a computed tomographic scan to assess component rotation. The 2 groups achieved satisfactory and similar knee scores; women had a significantly lower functional and patellar scores. The incidence of lateral patellar tilt, subluxation, and lateral impingement was decreased in weight-bearing axial views compared with non-weight bearing. Medial bony impingement was evident only in weight-bearing views and correlated with pain (P < .05).     

A clinical comparison of patellar tracking using the transepicondylar axis and the posterior condylar axis

Two different methods for femoral component rotation in total knee arthroplasty (TKA) were compared with regard to the need for lateral retinacular release and 3-year follow-up knee society scores of both patellofemoral function and 3-year radiographs of the patella. The posterior condylar axis was used in 1322 consecutive primary TKAs, and the transepicondylar axis (TEA) was used in 1059 consecutive primary TKA. A significant decrease in lateral retinacular release was observed from 56.9% (752 knees) using the posterior condylar axis down to 12.3% (130 knees) using the TEA. No significant differences in knee society scores were observed between the 2 groups with regard to stair climbing, pain, patella radiographs, or range of motion. Routine use of the TEA is recommended for determining femoral component rotation in TKA.     

The influence of femoral internal and external rotation on cartilage stresses within the patellofemoral joint

Internal and external rotation of the femur plays an important role in defining the orientation of the patellofemoral joint, influencing contact areas, pressures, and cartilage stress distributions. The purpose of this study was to determine the influence of femoral internal and external rotation on stresses in the patellofemoral cartilage. We constructed finite element models of the patellofemoral joint using magnetic resonance (MR) images from 16 volunteers (8 male and 8 female). Subjects performed an upright weight‐bearing squat with the knee at 60° of flexion inside an open‐MR scanner and in a gait laboratory. Quadriceps muscle forces were estimated for each subject using an electromyographic‐driven model and input to a finite element analysis. Hydrostatic and octahedral shear stresses within the cartilage were modeled with the tibiofemoral joint in a “neutral” position and also with the femur rotated internally or externally by 5° increments to ±15°. Cartilage stresses were more sensitive to external rotation of the femur, compared with internal rotation, with large variation across subjects. Peak patellar shear stresses increased more than 10% with 15° of external rotation in 75% of the subjects. Shear stresses were higher in the patellar cartilage compared to the femoral cartilage and patellar cartilage stresses were more sensitive to femoral rotation compared with femoral cartilage stress. Large variation in the cartilage stress response between individuals reflects the complex nature of the extensor mechanism and has clinical relevance when considering treatment strategies designed to reduce cartilage stresses by altering femoral internal and external rotation. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res     

Influence of Total Knee Arthroplasty on Patellar Kinematics and Patellofemoral Pressure

Background

Patellofemoral complications are one of the main problems after total knee arthroplasty (TKA). The design of the TKA component may affect the patellar biomechanics, which may be associated with this postoperative complication. The purpose of this study was to assess the influence of TKA and prosthesis designs on the patellar kinematics and patellofemoral pressure.

改良髌骨双骨道法自体股薄肌腱重建髌骨内侧支持带治疗复发性髌骨脱位

目的探讨改良髌骨双骨道法自体股薄肌腱重建髌骨内侧支持带（medial patellofemoral ligament,MPFL）治疗复发性髌骨脱位的临床效果,同时探讨解剖高危因素对术后效果的影响。方法2007年1月-2010年2月,对36例髌骨复发性脱位（单侧31例,双侧5例）采用改良髌骨双骨道法自体股薄肌腱重建MPFL,在髌骨内上缘由后内向前外向髌骨内1／2表面平行钻2个3．5mm骨道,将股薄肌腱引过骨道,将股薄肌腱的两游离端拉入股骨内侧骨道,屈膝30。位可吸收螺钉固定。对所有患者的Beighton评分,Q角,Insall指数,滑车发育不良分级,胫骨结节一滑车沟距离（TT—TG）等进行测量。临床评分采用Kujala,Lysholm和Tegner评分,同时调查患者的满意度。结果32例对手术的效果非常满意,3例满意,1例不满意。Kujala、Lysholm、Tegner评分分别由术前（64．34-15．0）、（65．1±18．6）、（3．2±1．1）分显著提高到术后（92．4±9．2）分（t=4．657,P=0．002）,（92．0±10．1）分（t=3．936,P=0．006）和（5．2±1．0）分（t=6．633,P=0．001）。80．6％（29／36）的患者在术后6—8个月恢复到受伤前的运动水平。1例术后1年再次髌骨脱位。97．6％（40／41）的膝关节存在股骨滑车发育不良,Beighton评分（5．2±2．5）分,Insall指数为1．22±0．14,Q角（13．6±3．9）°,TT-TG值（13．7±4．4）mm,与功能评分无相关性（P〉0．05）。结论自体股薄肌腱改良髌骨双骨道法重建MPFL是一种可靠安全经济的手术方法。高危解剖因素如高位髌骨、滑车发育不良、关节松弛等情况广泛存在于髌骨复发性脱位的患者中,虽未发现其严重程度会直接影响手术效果,但当复合因素存在时,仅重建MPFL的软组织手术可能不足以完全防止髌骨脱位复发。     

In vivo sagittal plane kinematics of the Avon patellofemoral arthroplasty

Isolated patellofemoral osteoarthritis can be treated with patellofemoral arthroplasty (PFA). In contrast to total knee arthroplasty, the effect of PFA on knee joint kinematics is not known. A study was performed to identify the kinematic changes after PFA. The sagittal plane kinematics was examined in 12 patients who had undergone Avon PFA. An established fluoroscopic method was used to examine the patellar tendon angle (PTA)/knee flexion relationship during functional activities. No significant difference existed between the kinematics of PFA knees compared with normal, except for a uniform elevation in PTA throughout the range. This increase in PTA in the PFA joint represents a 1.6-mm anterior displacement of the patella. The kinematic profile after PFA is close to normal and suggests that the knee is exhibiting more normal loading characteristics than those of the total knee arthroplasty joint.     

Six DOF in vivo kinematics of the ankle joint complex: Application of a combined dual‐orthogonal fluoroscopic and magnetic resonance imaging technique

Accurate knowledge of in vivo ankle joint complex (AJC) biomechanics is critical for understanding AJC disease states and for improvement of surgical treatments. This study investigated 6 degrees‐of‐freedom (DOF) in vivo kinematics of the human AJC using a combined dual‐orthogonal fluoroscopic and magnetic resonance imaging (MRI) technique. Five healthy ankles of living subjects were studied during three in vivo activities of the foot, including maximum plantarflexion and dorsiflexion, maximum supination and pronation, and three weight‐bearing positions in simulated stance phases of walking. A three‐dimensional (3D) computer model of the AJC (including tibia, fibula, talus, and calcaneus) was constructed using 3D MR images of the foot. The in vivo AJC position at each selected position of the foot was captured using two orthogonally positioned fluoroscopes. In vivo AJC motion could then be reproduced by coupling the orthogonal images with the 3D AJC model in a virtual dual‐orthogonal fluoroscopic system. From maximum dorsiflexion to plantarflexion, the arc of motion of the talocrural joint (47.5 ± 2.2°) was significantly larger than that of the subtalar joint (3.1 ± 6.8°). Both joints showed similar degrees of internal–external and inversion–eversion rotation. From maximum supination to pronation, all rotations and translations of the subtalar joint were significantly larger than those of the talocrural joint. From heel strike to midstance, the plantarflexion contribution from the talocrural joint (9.1 ± 5.3°) was significantly larger than that of the subtalar joint (?0.9 ± 1.2°). From midstance to toe off, internal rotation and inversion of the subtalar joint (12.3 ± 8.3° and ?10.7 ± 3.8°, respectively) were significantly larger than those of the talocrural joint (?1.6 ± 5.9° and ?1.7 ± 2.7°). Strong kinematic coupling between the talocrural and subtalar joints was observed during in vivo AJC activities. The contribution of the talocrural joint to active dorsi‐plantarflexion was higher than that of the subtalar joint, whereas the contribution of the subtalar joint to active supination–pronation was higher than that of the talocrural joint. In addition, the talocrural joint demonstrated larger motion during the early part of stance phase while the subtalar joint contributes more motion during the later part of stance phase. The results add quantitative data to an in vivo database of normals that can be used in clinical diagnosis, treatment, and evaluation of the AJC after injuries. © 2006 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res     

Total Knee Arthroplasty With Patellar Retention: The Severity of Patellofemoral Osteoarthritis Did Not Affect the Clinical and Radiographic Outcomes

Background

The purpose of this study is to compare the clinical and radiographic outcomes of total knee arthroplasty (TKA) with patellar retention in accordance with the severity of patellofemoral arthritis.

Using real‐time MRI to quantify altered joint kinematics in subjects with patellofemoral pain and to evaluate the effects of a patellar brace or sleeve on joint motion

Abnormal patellofemoral joint motion is a possible cause of patellofemoral pain, and patellar braces are thought to alleviate pain by restoring normal joint kinematics. We evaluated whether females with patellofemoral pain exhibit abnormal patellofemoral joint kinematics during dynamic, weight‐bearing knee extension and assessed the effects of knee braces on patellofemoral motion. Real‐time magnetic resonance (MR) images of the patellofemoral joints of 36 female volunteers (13 pain‐free controls, 23 patellofemoral pain) were acquired during weight‐bearing knee extension. Pain subjects were also imaged while wearing a patellar‐stabilizing brace and a patellar sleeve. We measured axial‐plane kinematics from the images. Females with patellofemoral pain exhibited increased lateral translation of the patella for knee flexion angles between 0°and 50° (p = 0.03), and increased lateral tilt for knee flexion angles between 0° and 20° (p = 0.04). The brace and sleeve reduced the lateral translation of the patella; however, the brace reduced lateral displacement more than the sleeve (p = 0.006). The brace reduced patellar tilt near full extension (p = 0.001), while the sleeve had no effect on patellar tilt. Our results indicate that some subjects with patellofemoral pain exhibit abnormal weight‐bearing joint kinematics and that braces may be effective in reducing patellar maltracking in these subjects. Published by Wiley Periodicals, Inc. J Orthop Res 27: 571–577, 2009     

Understanding patellofemoral pain with maltracking in the presence of joint laxity: Complete 3D in vivo patellofemoral and tibiofemoral kinematics

Patellofemoral pain is widely accepted as one of the most common pathologies involving the knee, yet the etiology of this pain is still an open debate. Generalized joint laxity has been associated with patellofemoral pain, but is not often discussed as a potential source of patellar maltracking. Thus, the objective of this study was to compare the complete 6 degree of freedom patellofemoral and tibiofemoral kinematics from a group of patients diagnosed with patellofemoral pain syndrome and maltracking to those from an asymptomatic population. The following null hypotheses were tested: kinematic alterations in patellofemoral maltracking are limited to the axial plane; knee joint kinematics are the same in maltrackers with and without generalized joint laxity (defined by a clinical diagnosis of Ehlers Danlos Syndrome); and no correlations exist between tibiofemoral and patellofemoral kinematics or within patellofemoral kinematics. This study demonstrated that alterations in patellofemoral kinematics, associated with patellofemoral pain, are not limited to the axial plane, minimal correlations exist between patellofemoral and tibiofemoral kinematics, and distinct subgroups likely exist within the general population of maltrackers. Being able to identify subgroups correctly within the omnibus diagnosis of patellar maltracking is a crucial step in correctly defining the pathophysiology and the eventual treatment of these patients. © 2008 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 27: 561–570, 2009     

关节镜辅助下内侧髌股韧带重建治疗急性髌骨脱位的中期随访

目的探讨关节镜辅助下内侧髌股韧带(medial patellofemoral ligament, MPFL)重建治疗急性髌骨脱位(acute patellar dislocation, APD)的中期临床疗效。方法 2016年3月至2018年3月,我科采用关节镜辅助下MPFL重建手术治疗19例APD病人,其中男7例,女12例;年龄为(21.5±6.3)岁。所有病人于术中进行关节镜检查,评估髌骨轨迹,然后进行MPFL重建。术后6个月随访复查X线片及膝关节CT,测量膝关节Q角,采用Lysholm评分评价病人术后膝关节功能情况。结果术后所有病人均获随访,随访时间为(11.7±5.3)个月。术后无髌骨再脱位发生,恐惧试验阴性,关节功能恢复良好。术后6个月,19例病人的髌骨Q角为15.37°±1.46°,较术前的17.63°±1.83°显著减小,差异具有统计学意义(t=5.938,P<0.001);术后6个月19例病人的膝关节Lysholm评分为(90.47±2.83)分,较术前的(67.63±7.14)分明显提高,差异具有统计学意义(t=-16.052,P<0.001)。结论关节镜辅助下MPFL重建治疗APD的中期临床效果良好。