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目的:探讨吸烟对老年男性血中甘油三酯水平的影响。方法:对本院2007-2010年就诊的老年男性患者572例的临床资料进行回顾性分析,按吸烟史分为吸烟组与非吸烟组,其中吸烟组468例,非吸烟组104例,比较吸烟组与非吸烟组的血清甘油三酯的水平差异,按甘油三酯水平分为高甘油三酯组327例和正常甘油三酯组245例,并分析影响甘油三酯水平的相关因素。结果:吸烟组甘油三酯平均水平为(3.07±1.29)mmol/L明显高于不吸烟组(1.42±0.45)mmol/L,差异有统计学意义(P〈0.05)。影响甘油三酯水平的相关因素分析表明,体重、吸烟数量、吸烟年限与甘油三酯水平呈正相关(r=0.594,P〈0.05),而年龄和身高与甘油三酯水平无明显相关性(r=0.037,P〉0.05),采用Logistic回归分析提示,甘油三酯水平随吸烟数量、吸烟年限的增加而增高。结论:吸烟对老年男性甘油三酯水平具有重要的影响,提倡禁烟。 相似文献
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目的探讨2型搪尿病血糖控制对空腹、餐后血脂的影响.方法将53例2型糖尿病患者按不同锫化血红蛋白水平分为3组,观察各组空腹、餐后甘油三酯及其它血脂成份变化.结果糖化血红蛋白>10%组较搪化血红蛋白8%~10%及<8%组餐后甘油三酯明显增高,具有显著差异(P<0.05);对三组餐后甘油三酯与空腹甘油三酯进行的相关分析显示,餐后甘油三酯水平与空腹甘油三酯水平具有显著的正相关(P<0.001).结论随着血糖控制的改善,空腹及餐后甘油三酯下降,提示2型糖尿病血糖控制对降低甘油三酯有重要意义. 相似文献
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观察不同磷脂 /甘油三酯比的脂肪乳剂对血脂的影响。取大鼠随机分成三组 ,分别经上腔静脉插管输入等热量的磷脂 /甘油三酯比分别为 0 .0 6和 0 .12的脂肪乳剂 ,或不做处理。连续应用 2 4h。于实验后检测甘油三酯、磷脂、胆固醇的变化。结果 :应用脂肪乳剂后血甘油三酯两组均有提高 ,但各组间无明显差别。然而 ,与应用磷脂 /甘油三酯比为 0 .0 6的脂肪乳剂相比 ,输入磷脂 /甘油三酯比为 0 .12的脂肪乳剂后 ,血磷脂、胆固醇显著升高。结论 :磷脂 /甘油三酯比而不是甘油三酯是引起血脂蓄积的原因 ,应用低磷脂 /甘油三酯比的脂肪乳剂可减少血脂… 相似文献
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目的了解便携式血脂仪测定胆固醇及甘油三酯的准确性和与生化实验室所测结果的相关性,探讨便携式血脂仪测定的质量控制方法。方法采用血糖胆固醇甘油三酯三用检测仪测定60例病人空腹时的微血管全血甘油三酯(TG)和胆固醇(TCH),同时静脉采血用自动生化分析仪测定血清甘油三酯和胆固醇。结果快速血脂仪与自动生化分析仪间存在系统差异,血脂仪测定值略低于生化检测结果,但无统计学差异,两者均有很好的相关性,相关系数都达到0.72以上,胆固醇较甘油三酯相关性更好。结论血糖胆固醇甘油三酯三用检测仪所测值能反映血脂浓度,所测结果胆固醇较甘油三酯更可靠,采取必要的措施可以保证获取准确的结果。 相似文献
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高脂肪、蔗糖膳食致肥胖的作用机理研究 总被引:7,自引:1,他引:6
目的:探讨高脂肪、蔗糖膳食的致肥胖作用机理。方法:应用高胰岛素血症的下丘脑腹内侧核损伤性肥胖大鼠和正常胰岛素水平的SD大鼠,饲以高脂肪、蔗糖和正常饲料,观察甘油三酯的代谢、胰岛素、脂蛋白脂酶活性的变化,分析胰岛素与甘油三酯生成、脂蛋白脂酶活性的相关关系。结果:高脂肪膳食具有明显的增加体重和脂肪的作用,但高蔗糖膳食仅有促进脂肪生成的作用;两者均可引起胰岛素水平的升高,升高的胰岛素水平提高脂蛋白酯酶的活性。高脂肪膳食引起外源性甘油三酯的升高,在脂蛋白脂酶的作用下,外源性甘油三酯进入脂肪细胞;高蔗糖膳食通过胰岛素的作用,促进内源性甘油三酯的分泌,在脂蛋白脂酶的作用下,内源性甘油三酯进入脂肪细胞。结论:高脂肪膳食和高蔗糖膳食导致肥胖的作用机理并不相同,不同之处是前者引起外源性甘油三酯的升高,后者促进内源性甘油三酯的产生。相同之处是两种膳食均引起胰岛素水平升高,升高的胰岛素水平提高脂蛋白酯酶活性,在脂蛋白酯酶的作用下,甘油三酯进入脂肪细胞。 相似文献
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目的:观察不同磷脂/甘油三酯比的脂肪乳剂对血脂的影响。方法:雄性Wistar大鼠随机分成3组,分别经上腔静脉插管输入等热量的磷脂/甘油三酯比分别为0.06和0.12的脂肪乳剂或不做处理,连续应用24h。于实验后检测 油三酯,磷脂,胆固醇的变化。结果:应用脂肪乳剂后血甘油三酯两组均有提高,但各组间无明显差别。但与应用磷脂/甘油三酯比为0.06的脂3肪乳剂相比,输入磷脂/甘油三酯比为0.12的脂肪乳剂后,血磷脂,胆固醇显升高,结论:磷脂/甘油三酯比而非甘油三酯是引起血脂蓄积的原因,应用低磷脂/甘油三酯比的脂肪乳剂可减少血脂蓄积。 相似文献
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目的探讨单纯高甘油三酯血症患者血清细胞间粘附分子-1(sICAM-1)的变化及其对早期预测动脉粥样硬化的意义.方法利用^125I-sICAM-1放射免疫分析(RIA)方法测定35例单纯高甘油三酯血症患者和33例健康人血清sICAM-1水平.结果单纯高甘油三酯血症患者血清sICAM-1水平高于对照组(P<0.01),且血清sICAM-1与甘油三酯呈正相关(P<0.01),多元逐步回归显示甘油三酯为影响血清sICAM-1最为显著的因素(R^2=0.53).结论sICAM-1表达增加可能与高甘油三酯血症相关,有助于早期预测动脉粥样硬化病变的发生. 相似文献
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目的探讨企业职工高尿酸血症(HUA)与血压、血脂、血糖的相关性,为企业进行健康管理提供依据。方法以中国石油长庆油田公司各下属企业为抽样单位,整群随机抽取2个单位,每个单位中所有的HUA者作为HUA组,共720人;同时在尿酸水平正常者中随机选取620人为正常组。通过Logistic回归分析HUA与年龄、性别、血压、血脂、血糖的关系。结果HUA合并高血压、高血脂、空腹m糖受损任意一项、两项、三项的比例均远高于正常组(OR值分别为:4.036,2.562,4.174)。多因素Logistic回归发现:男性、收缩压、总胆固醇、三酰甘油、低密度脂蛋白胆固醇是HUA的危险因素(OR值分别为7.736,2.309,1.721,2.761,1.411);高密度脂蛋白胆固醇为HUA的保护因素(OR值为0.211)。结论HUA存在性别差异,且与血压、血脂密切相关。企业对职工的健康管理应充分考虑多危险因素的综合作用,全面的进行健康教育及干预。 相似文献
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Trina M. Aguirre Ann E. Koehler Ashish Joshi Susan L. Wilhelm 《Ethnicity & health》2018,23(1):111-119
Objective: Addressing health disparities requires well designed, culturally adapted research. However, recruiting/retaining minority participants has often been challenging. We present strategies used to successfully recruit and retain rural Hispanic women during a breastfeeding education intervention.Design: This study involved a two-group repeated measures quasi-experimental design with assessments at seven intervals between enrollment and 6 months postpartum. Participants (Hispanic women?≥?15 years old) were recruited through a regional hospital.Results: We successfully met our recruitment goals, most women contacted were enrolled (46 of 58), and 100% completed the study.Discussion: Research staff with ties within the community helped establish trust. Using bilingual study materials, simple language, and an interpreter addressed language/literacy concerns. Phone assessments facilitated participation as transportation was an issue. Accommodating requests to deliver or mail study materials and providing incentives were important. Extra effort was needed to maintain contact when phone service was disrupted or participants moved. Keys to success were persistence, flexibility, and alleviating barriers to participation. 相似文献
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目的:分析初产妇、经产妇心理状态特点,以便采取更有效的干预措施。方法筛选2014年6月至2015年1月在咸阳市旬邑县妇幼保健院产科门诊产前检查的健康初产和经产妇各60名,孕周为28~40周。入组时用焦虑自评量表( SAS)、抑郁自评量表(SDS)对两组孕妇进行心理评定,并给1次支持性心理干预(40~60分钟),1周后再次用SAS、SDS对两组孕妇进行评定分析。结果经产妇干预前SAS(50.73±3.45)、SDS(49.13±3.86)评分明显高于初产妇SAS(42.45±2.08)、SDS(41.77±2.21),差异均有统计学意义(t值分别为-15.921、-12.817,均P<0.01);干预后两组SAS、SDS评分均比干预前明显降低,差异均有统计学意义(t值分别为14.999、15.413;15.724、15.832,均P<0.01);干预后经产妇 SAS(38.61±5.02)、SDS(39.10±3.03)评分明显高于初产妇SAS(34.88±3.31)、SDS(32.01±4.27),差异均有统计学意义(t值分别为-4.805、-10.489,均P<0.01)。结论初产妇和经产妇均伴有焦虑、抑郁情绪,干预前后经产妇抑郁、焦虑情绪均较初产妇明显,支持性心理干预能有效改善孕妇的不良情绪。 相似文献
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超重肥胖已成为世界各国儿童青少年面临的重大公共卫生问题之一。现行的儿童青少年超重肥胖筛查标准不统一,逐条评价或自行编写程序容易出错且效率较低。本研究以中国学龄儿童青少年超重与肥胖筛查标准为例,详细介绍了国际和中国共四种评价儿童青少年超重肥胖的方法和步骤,结合具体案例详细介绍其应用方法,同时编制SPSS和SAS程序包和解... 相似文献
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《Health & place》2022
We used data from the Fragile Families and Child Wellbeing Study which includes a sample of adolescents of age 15 at the most recent wave (between 2014 and 2017) from mainly low-income urban families in the United States, to examine the association between neighborhood poverty entries and exits and adolescent depression and anxiety. In addition, we examined whether these associations differed by gender. Adolescents who consistently lived in disadvantaged neighborhoods had the highest level of depression and anxiety. Those who entered poor neighborhoods were more depressed than those who never lived in poor neighborhoods. Those who exited poor neighborhoods showed no significant difference in depression and anxiety compared to those never lived in poor neighborhoods. Furthermore, these associations applied to adolescent girls only and were not statistically significant for boys. The results suggest that neighborhood poverty has cumulative negative impacts on adolescent mental health and disproportionally affects adolescent girls. Reducing neighborhood poverty would substantially improve the health of adolescents, especially girls, which would reduce health disparities. 相似文献
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Enabling positive change: Progress and setbacks in HIV and sexual and reproductive health and rights
Purnima Mane 《Global public health》2018,13(10):1341-1356
At a point in history when the future of sexual and reproductive health including HIV looks particularly uncertain, it is helpful to recognise that many of the challenges currently faced are neither new nor insurmountable. Reflecting on past achievements and lessons learned helps us to have confidence that positive change is feasible. This paper reflects on some of the changes observed in countries like India and Mozambique and identifies a range of factors which need to coalesce to enable these developments, along with specific contextual factors. It is the combination of these influences rather than any one of them alone that brought about the change in the three instances described – fostering a positive political response to HIV in its early years in India; bringing about policy reform on abortion in Mozambique; and increasing contraceptive prevalence and age at marriage in some districts in Bihar, India. Change is always fragile and susceptible to setbacks, but change-seekers can learn in the process and gain renewed hope that progress can and often does take place if they persevere. 相似文献
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骨钙素是成骨细胞分泌的骨蛋白 ,骨钙素水平与成骨细胞活性成正相关 ,是一项很好的反映骨形成与骨转化的生化指标。小儿骨生长发育有自身特点 ,骨钙素水平的改变类似儿童身高生长曲线 ,可以很好地应用于评价儿童生长发育及监测生长障碍患儿对治疗的反应 相似文献