Facet joint degeneration as a cause of low back pain

Recognizing that not all patients with low back pain have lumbar disc disease, the authors began to inject facet joints in June 1982 and have experience now with 21 patients, each injected under fluoroscopic control with a mixture of local anesthetic and steroid. One technical problem occurred when large osteophytes blocked access to the facet joints. Otherwise, there were no complications and minimal morbidity. Most patients (15 of 20; 75%) had an initial response, but a much smaller number (six of 18 followed more than three months; 33%) had a lasting response. Repeat injections, when done, always led to temporary improvement but rarely to lasting relief (one of five; 20%). Three factors characterized the patients: a negative screening examination for other causes of back pain or sciatica; back pain with tenderness localized over one or more facet joints; and radiologic changes of degenerative joint disease within the facet joints. Facet joint disease may be a significant cause of low back pain. The above three criteria are useful in clinical identification of patients with this problem. Facet joint injections play an important role in the diagnosis and treatment of low back pain.     

Local corticosteroid injections for low back pain and sciatica

In patients with symptoms caused by intervertebral disk displacement, studies of epidural corticosteroid injections have produced compelling evidence of a short-term analgesic effect (lasting about 3 weeks), despite a number of discrepancies. In contrast, no reductions were noted in the time off work or need for surgery. Strong evidence supports a short-term symptomatic effect of guided transforaminal corticosteroid injections, and there is also some evidence of a long-term effect. Further work is needed to assess the potential of this treatment modality for decreasing surgical requirements in patients who fail conventional nonsurgical treatment. Facet-joint injections may produce pain relief in some patients with common low back pain. This modality can be offered to selected patients who fail to respond to first-line treatment. Epidural injections are not appropriate in patients with acute low back pain. They may offer short-term symptom relief to patients experiencing acute exacerbations of chronic low back pain, in whom they are used as an ancillary method. Intradural injections should not be performed, as they may induce adverse effects and have not been proved effective. Interspinous injections and iliolumbar ligament injections can be considered in selected patients. Although published data have led to controversy about the effectiveness of local corticosteroid injections, a short-term analgesic effect is usually obtained, making this modality useful for the second-line treatment of patients with disk-related sciatica, as well as in selected patients with chronic low back pain.     

Patient satisfaction with spinal cord stimulation for predominant complaints of chronic, intractable low back pain.

BACKGROUND CONTEXT: Results of subsequent surgical intervention in patients with intractable pain after lumbar spine surgery are typically worse than for initial surgery, particularly in those with predominant complaints of back pain rather than lower extremity pain. Spinal cord stimulation (SCS) has been found to yield good results in patients with primary complaints of intractable lower extremity pain. Technological advances have broadened the indications for this treatment. PURPOSE: The purpose of this study was to evaluate patient satisfaction after SCS in the treatment of patients with predominant complaints of chronic, intractable, low back pain. STUDY DESIGN/SETTING: Data were collected from retrospective chart review and patient follow-up questionnaire. Patients were treated at a spine specialty center. PATIENT SAMPLE: The study group consisted of the consecutive series of our first 41 patients who underwent SCS for predominant complaints of low back pain. The mean symptom duration was 82.9 months, and the mean age was 47.9 years (range, 28-83 years). All but three patients had previously undergone lumbar spine surgery (mean, 2.3 prior surgeries). OUTCOME MEASURES: At the time of follow-up (5.5-19 months after SCS implantation), patients completed questionnaires assessing their satisfaction with their outcome, if they would have the procedure again knowing what their outcome would be and if they would recommend SCS to someone with similar problems. In determining outcome, a negative response was assigned for patients who had the device removed. A worst-case analysis was also conducted in which a negative response was assigned for patients lost to follow-up or who failed to respond to a particular question. Data were also collected on complications and re-operations. METHODS: All trial stimulation procedures were performed under local anesthetic with the patient providing feedback concerning pain relief achieved with various lead placements and settings. If one lead did not provide acceptable relief in all the areas needed, placement of a second lead was pursued. If the patient failed to maintain acceptable pain relief (> or =50% pain relief) during a multiday trial period, the leads were removed. If adequate relief was maintained during the trial period, the receiver was implanted. RESULTS: Responses to the follow-up questionnaire indicated that 60% of patients considered themselves improved from their preoperative condition and the remaining 40% did not; 78.1% of patients would recommend SCS to someone with similar problems, 69.0% were satisfied, 75.0% would have the procedure performed again if they had known their outcome before implantation. Among the 36 patients in whom the system was implanted, it was later removed in 4 because of lack of sufficient pain relief. Other re-operations included repositioning of the leads to regain pain relief in the areas needed, replacement of a malfunctioning unit and revision of lead extension wires. CONCLUSIONS: In this retrospective study, the majority of patients were satisfied with the results of SCS and would have the procedure again knowing what their outcome would be. These results suggest that further investigation of SCS is warranted in this difficult to treat patient population presenting with predominant complaints of chronic, intractable, axial low back pain.     

Lumbar facet joint syndrome. A randomised clinical trial

A group of 109 patients with unilateral low back pain for over three months were randomised to receive one of three types of injection treatment: cortisone and local anaesthetic injected into two facet joints (28), the same mixture around two facet joints (39), or physiological saline into two facet joints (42). The effect of the treatment was evaluated in relation to work attendance, pain, disability and movements of the lumbar spine. Patients were examined one hour and two and six weeks after treatment and also completed a questionnaire after three months. A significant improvement was observed in work attendance, pain and disability scores, but this was independent of the treatment given and movements of the lumbar spine were not improved. Of the 70 patients with initial pain relief after injection, 36% reported persisting benefit at the three month follow-up, independent of the mode of treatment given. We conclude that facet joint injection is a non-specific method of treatment and the good results depend on a tendency to spontaneous regression and to the psychosocial aspects of back pain.     

Beyond opioid patient-controlled analgesia: a systematic review of analgesia after major spine surgery

Postoperative pain control in patients undergoing spine surgery remains a challenge for the anesthesiologist. In addition to incisional pain, these patients experience pain arising from deeper tissues such as bones, ligaments, muscles, intervertebral disks, facet joints, and damaged nerve roots. The pain from these structures may be more severe and can lead to neural sensitization and release of mediators both peripherally and centrally. The problem is compounded by the fact that many of these patients are either opioid dependent or opioid tolerant, making them less responsive to the most commonly used therapy for postoperative pain (opioid-based intermittent or patient-controlled analgesia). The purpose of this review was to compare all published treatment options available that go beyond intravenous opiates and attempt to find the best possible treatment modality.     

Persistent local pain after posterior spine surgery for thoracic lesions

Many surgeons have investigated local pain associated with posterior spine surgery for cervical or lumbar lesions. However, little information is available concerning local pain after posterior thoracic spine surgery. This prospective study was, thus, performed to investigate the frequency and clinical features of local pain after posterior spine surgery for thoracic lesions. In 29 consecutive patients undergoing posterior spine surgery for various thoracic spinal disorders, local pain was investigated before and after surgery. In all 19 patients with preoperative back pain presumably due to thoracic lesions, pain was well alleviated after surgery. In contrast, 6 patients (21%) newly developed persistent shoulder angle pain after surgery, which resembled axial pain after cervical laminoplasty. In 5 of these 6 patients surgical exposure was extended to the cervicothoracic junction, whereas persistent shoulder angle pain was independent of disease etiologies and surgical procedure, and all of the 5 patients had no other etiologies of local pain such as surgical site infections, hardware failures, pseudoarthrosis, other metastasis, and vertebral fractures. These results suggest that dissection of muscle attachments to the cervicothoracic junction would play some part in the development of persistent local pain after posterior spine surgery for thoracic lesions, although surgical exposure of the zygapophysial joints at the cervicothoracic junction might be a possible source of postoperative shoulder pain. Therefore, to minimize such surgical complications, muscle insertions into the cervicothoracic junction should be preserved as far as possible.     

Percutaneous epidural neuroplasty: Prospective evaluation of 0.9% NaCl versus 10% NaCl with or without hyaluronidase

Background and Objectives. Percutaneous epidural neuroplasty (epidural neurolysis, lysis of epidural adhesions) is an interventional pain management technique that has emerged over approximately the last 10 years as part of a multidisciplinary approach to treating radiculopathy with low back pain. In addition to local anesthetic and corticosteroid, hypertonic saline (10% NaCl) and hyaluronidase are used for the technique. The objective of this study was to determine if hypertonic saline or hyaluronidase influenced treatment outcomes. Methods. Eighty-three subjects with radiculopathy plus low back pain were assigned to one of four epidural neuroplasty treatment groups: (a) hypertonic saline plus hyaluronidase, (b) hypertonic saline, (b) isotonic saline (0.9% NaCl), or (d) isotonic saline plus hyaluronidase. Subjects in all treatment groups received epidural corticosteroid and local anesthetic. Results. Twenty-four subjects did not complete the study. Most of the other 59 subjects receiving any of the four treatments as part of their pain management obtained significant relief immediately after treatment. Visual analog scale (VAS) scores for the area of maximal pain (VAS_max, back or leg) were reduced in 25% or more of subjects in all treatment groups at all post-treatment follow-up times (1, 3, 6, 9, and 12 months). A smaller fraction of subjects treated with hypertonic saline or hyaluronidase and hypertonic saline required more additional treatments than did subjects receiving the other treatments. Conclusions. Percutaneous epidural neuroplasty, as part of an overall pain management strategy, reduces pain (sometimes for over one year) in 25% or more of subjects with radiculopathy plus low back pain refractory to conventional therapies. The use of hypertonic saline may reduce the number of patients that require additional treatments.     

Viscosupplementation in lumbar facet joint arthropathy: a pilot study

BACKGROUND: Degeneration of the spine is a prevalent problem that generally advances with age, although its occurrence is not restricted to the elderly. Chronic low back pain is a common problem with several treatments, but rigorous evaluation of many interventions is still lacking. One of the most common methods of treating lumbar facet arthropathy is intra-articular injection of local anesthetic and steroid. However, in large joints, such as the knee, viscosupplementation has been shown to compare favorably to steroid in terms of symptom relief and duration of benefit. It is suggested that viscosupplementation may supersede steroid in treatment of symptomatic knee osteoarthritis. Hyaluronic acid (HA) therapy is still in its infancy in joints outside the knee, although some preliminary results are promising. OBJECTIVE: This was a pilot study to test the potential effectiveness of HA injection therapy in the treatment of lumbar facet joint arthritis. METHODS: Thirteen patients with symptomatic lumbar facet joint arthritis who met the inclusion criteria were prospectively recruited. Pretreatment evaluation of patients was by questionnaire, including the Visual Analog Score and Oswestry Disability Questionnaire. A single injection of HA into affected facet joints was then performed, with correct placement confirmed on fluoroscopy. The patients were similarly evaluated 6 weeks after treatment. RESULTS: Eighteen facets in 13 patients were injected with HA. At 6-week follow up, there was no significant improvement in pain when measured on the Visual Analog Score. There was also no significant improvement in the Oswestry Disability Questionnaire. CONCLUSIONS: Preliminary results from this pilot study do not demonstrate any benefit of viscosupplementation in the management of symptomatic lumbar facet arthropathy.     

Ageing and degenerative changes of the intervertebral disc and their impact on spinal flexibility

Purpose

Degeneration of the intervertebral disc is associated with various morphological changes of the disc itself and of the adjacent structures, such as reduction of the water content, collapse of the intervertebral space, disruption and tears, and osteophytes. These morphological changes of the disc are linked to alterations of the spine flexibility. This paper aims to review the literature about the ageing and degenerative changes of the intervertebral disc and their link with alterations in spinal biomechanics, with emphasis on flexibility.

Methods

Narrative literature review.

Results

Clinical instability of the motion segment, usually related to increased flexibility and hypothesized to be connected to early, mild disc degeneration and believed to be responsible for low back pain, was tested in numerous in vitro studies. Despite some disagreement in the findings, a trend toward spinal stiffening with the increasing degeneration was observed in most studies. Tests about tears and fissures showed inconsistent results, as well as for disc collapse and dehydration. Vertebral osteophytes were found to be effective in stabilizing the spine in bending motions.

Conclusions

The literature suggests that the degenerative changes of the intervertebral disc and surrounding structures lead to subtle alteration of the mechanical properties of the functional spinal unit. A trend toward spinal stiffening with the increasing degeneration has been observed in most studies.

     

Treadmill ambulation with partial body weight support for the treatment of low back and leg pain

STUDY DESIGN: A single-subject experimental design using an A-B-A treatment protocol. OBJECTIVE: To determine whether walking on a treadmill with partial body weight support (PBWS) would be an effective adjunct treatment method to standard care for decreasing pain and increasing function in patients suffering from low back and leg pain. BACKGROUND: Mechanical low back pain (LBP) is commonly aggravated by activities that increase axial loading in the spine, such as sitting, standing, and walking. Patients with mechanical LBP usually describe relief with positions that unload the spine. One traction technique now being used in clinics to unload the spine is the PBWS system. The use of endurance exercise has also been found to be a consistent predictor of better outcomes in patients with LBP. Thus treatment that combines spinal unloading using PBWS and endurance exercise may be an effective intervention for patients with low back and leg pain. METHODS AND MEASURES: Eleven subjects participated in this study using an A-B-A design. Phase A was defined as the baseline condition and phase B was intervention with PBWS provided by a mechanical unloading system. The Roland-Morris Questionnaire (RMQ) and Visual Analog Scale (VAS) were utilized to collect data on functional status and perceived pain, respectively. Visual Analysis and 2 standard deviation band method (2SDBM) were used to analyze the data. RESULTS: Pain scores between baseline and PBWS treatment phases were significantly improved for 3 out of the 6 subjects who completed the study. RMQ baseline and treatment scores revealed that 5 out of 6 subjects had significant functional improvements in the PBWS treatment phase. CONCLUSION: The results suggest that ambulation with PBWS combined with the standard level of care for this population holds sufficient promise for pain relief and functional improvement to justify testing its efficacy in larger groups of subjects with these complaints.     

Musculo-skeletal mechanisms of low back pain]

Authors presented in comprehensive form updated knowledge concerning reasons and mechanisms of musculoskeletal back pain nonspecific symptom which in majority of cases, provides only little inside into the nature of the underlying problem. The physician must however find sufficient time to educate the patient as to the nature of this disorder and likely course during treatment. Understanding the source and mechanisms of the patients pain allows the physician and patient to approach the problem rationally with mutual confidence. The basic aim of the physician is exact identification of the anatomic source of pain and exclude the possibility of underlying systemic or malignant process that might threaten the patient's life. The musculoskeletal system consists of the bones and articulations, ligaments, muscles and tendons, that connect and manipulate them within spinal column. All of these tissues are richly innervated and specific biomechanical conditions cause, that lumbar part of the spine and lumbosacral junction are extremely susceptible to direct and indirect affected by a spectrum of reasons causing pain. The pathomechanism of the pain originating within the facet joints, bone and periosteum, paraspinous muscles and tendons, intervertebral disks, posterior longitudinal ligament and dorsal root ganglion was discussed. Although in majority of causes it possible to control localized pain by means of conservative treatment, however in some patients (0.5%-1%) surgery is needed to decompress neurologic structures, restore stability, and eliminate pain.     

Therapeutic arthrography and bursography

Arthrography and bursography as therapeutic venues have found their place in the musculoskeletal procedure armamentarium. Therapeutic arthrography not only rules in and rules out the origin of pain but can provide 6 to 9 months of pain relief in diseased joints. Therapeutic arthrography allows injections of anesthetic, corticosteroid, or alternatively hyaluronic acid to be delivered accurately to the source of pain. Corticosteroids have a long history of use in osteoarthritis. Alternative therapy with hyaluronic acid is anew procedure. This article reviews the technique of arthrography in different joints and bursae and discusses the pros and cons of the use of corticosteroids versus viscosupplementation in therapeutic arthrography.     

Infiltration of anomalous lumbosacral articulations. Steroid and anesthetic injections in 10 back-pain patients

In 10 patients with severe, chronic low back pain, we studied the effect of steroid and local anesthetic infiltration of anomalous lumbosacral articulations, formed between a transitional lumbosacral vertebra and the sacrum. There was immediate total relief of pain in 8 patients, and in 1 patient immediate partial relief that became total after approximately 7 days. Five patients subsequently relapsed to their former pain level in periods ranging from 1 day to 12 weeks, 3 patients continued to report adequate partial pain relief after periods of 7 to 41 months, and 1 patient remained free from pain 2 years after infiltration. IN some cases, infiltration of these articulations may be therapeutic, as well as diagnostic.     

Zervikale Bandscheibe

The spinal intervertebral disc can cause neurocompression or pain as a result of degeneration. Surgical interventions, therefore, include decompression, fusion, disc replacement or a combination thereof. Identifying the painful segment in the case of axial pain requires accurate segment diagnosis and may require invasive diagnostic measures (joint infiltration, discography), since imaging is often not fluid enough. In the case of fusion following disc removal, the placeholder is substitued in the form of a cage or autologous iliac crest graft. Alternatively, when dorsal elements are intact, a disc prosthesis can be inserted. In the case of compression, removal of the compromised structures (disc, osteophytes) becomes necessary. If the indication is correctly made and the appropriate surgical technique used, good results can be expected from cervical spine surgery.     

Infiltration of anomalous lumbosacral articulations: Steroid and anesthetic injections in 10 back-pain patients

In 10 patients with severe, chronic low back pain, we studied the effect of steroid and local anesthetic infiltration Of anomalous lumbosacral afticulations, formed between a transitional lumbosacral vertebra and the sacrum. There was immediate total relief of Pain in 8 Patients, and in 1 Patient immediate partial relief that became total after approximately 7 days. Five patients subsequently relapsed to their former pain level in periods ranging from 1 day to 12 weeks, 3 patients continued to report adequate partial pain relief after periods of 7 to 41 months, and 1 patient remained free from pain 2 years after infiltration. In some cases, infiltration of these articulations may be therapeutic, as well as diagnostic.     

Influence of facet joint angles and asymmetric disk collapse on degenerative olisthesis of the cervical spine

This study examined the facet angles of the joint facets of the intervertebral joints, the anterior and posterior heights of the intervertebral disks, and cervical lordosis as possible parameters of olisthesis. Lateral radiographs of the cervical spine in 123 patients were examined, and parameters were correlated to anterolisthesis and retrolisthesis in each segment. Results indicate anterolisthesis is caused by a decrease of the facet angles of the caudal joint facets. This process is favored by loss of anterior height of the intervertebral disks and a flattened position of the cervical spine. Loss of posterior height of the intervertebral disks promotes retrolisthesis.     

Anterior operations in cervicarthrosis and vertebral artery compression

Pain in the cervical spine in the course of degenerative changes is a frequent complaint reported by patients seeking the help of various specialists. Depending on the location of pathologic changes, the pain in the spine may be accompanied by a whole array of signs and symptoms, which are sometimes more troublesome for the patient than the back pain itself. The symptoms are sometimes so persistent and difficult to treat that they lead the patient to apathy and depression, even to the point of suicidal attempts. Should serious aggravation of symptoms develop despite all efforts at successful conservative therapy, surgical treatment is employed to remove the osteophytes protruding into the lumen of the vertebral canal and compressing the spinal roots. An analysis from 1969 to 1988 of treatment in 237 patients with neurologic disorders and concomitant or dominant disturbances of blood flow in vertebral arteries showed that there are specific indications for surgical decompression of the arteries, i.e., when lumen is constricted by the osteophytes at the level of uncovertebral joints. In a series of 47 patients, 42 cases were found to be pain free.     

Lumbar spine postures in Marines during simulated operational positions

Low back pain has a 70% higher prevalence in members of the armed forces than in the general population, possibly due to the loads and positions soldiers experience during training and combat. Although the influence of heavy load carriage on standing lumbar spine posture in this population is known, postures in other operationally relevant positions are unknown. Therefore, the purpose of this study was to characterize the effect of simulated military operational positions under relevant loading conditions on global and local lumbar spine postures in active duty male US Marines. Secondary objectives were to evaluate if intervertebral disc degeneration and low back pain affect lumbar spine postures. Magnetic resonance images were acquired on an upright scanner in the following operational positions: Natural standing with no external load, standing with body armor (11.3 kg), sitting with body armor, and prone on elbows with body armor. Custom software was used to measure global lumbar spine posture: Lumbosacral flexion, sacral slope, lordosis, local measures of intervertebral angles, and intervertebral distances. Sitting resulted in decreased lumbar lordosis at all levels of the spine except L1–L2. When subjects were prone on elbows, a significant increase in local lordosis was observed only at L5–S1 compared with all other positions. Marines with disc degeneration (77%) or history of low back pain (72%) had decreased lumbar range of motion and less lumbar extension than healthy Marines. These results indicate that a male Marine's pathology undergoes a stereotypic set of postural changes during functional tasks, which may impair performance. © 2017 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:2145–2153, 2017.

     

The diagnostic and predictive value of hip anesthetic arthrograms in selected patients before total hip arthroplasty

Concurrent osteoarthritis of the hip and lumbar spine occurs frequently. Our study tests the hypothesis that hip anesthetic arthrograms can be used as predictive diagnostic tool before total hip arthroplasty when standard evaluation techniques fail to provide convincing evidence of the source of pain. Thirty-four consecutive hip anesthetic arthrograms were reviewed retrospectively. Quantified outcome measures included Visual Analog Pain Score, Harris Hip Score, and patient satisfaction. The pain relief after hip anesthetic arthrogram accurately predicted pain relief after hip arthroplasty (positive predictive value = 95.23%, negative predictive value = 87.5%). Our study supports the selected use of hip anesthetic arthrograms in the preoperative assessment of patients with concurrent hip and lumbar spine osteoarthritis associated with nondiagnostic history and physical examinations.     

Typical MRI findings in sports medicine evaluation for degenerative disc disease

Sports medicine patients are a subgroup who may be prone to low back pain. CT evaluation, while accurate, exposes patients to ionizing radiation, especially critical in the younger age group. A large number of general orthopaedic patients with low back pain unresponsive to conservative therapy were examined with conventional lateral sagittal and the more flexible oblique multislice axial images. Conventional lateral views alone were found to be insufficient in the accurate diagnosis of degenerative disc disease and must be complemented by oblique axial imaging if MRI is to be used as the primary spine imaging modality, for sports medicine imaging. This paper presents normal and pathologic anatomy as seen with oblique axial surface coil MR lumbar spine imaging. J Orthop Sports Phys Ther 1989;10(8):290-296.