Reconstructions of the shoulder following tumour resection

PURPOSE: To review and compare the postoperative outcomes of 3 types of shoulder reconstructions: prosthetic arthroplasty, clavicula pro humero reconstruction, and allograft arthrodesis. METHODS: Records of 25 shoulder reconstructions following tumour resection were retrospectively reviewed. Perioperative data, oncological prognoses, postoperative complications, and functions were assessed. RESULTS: We performed 10 prosthetic arthroplasties, 7 clavicula pro humero procedures, 4 allograft arthrodeses, and 4 soft tissue reconstructions. Eight patients died of their diseases. Three developed complications and underwent revision surgery. 19 patients achieved stable shoulders. Ten patients attended for functional assessments. Respective mean scores using the Musculoskeletal Tumor Society-International Symposium on Limb Salvage and the Toronto Extremity Salvage Score were: 77% and 82% for prosthetic arthroplasties, 67% and 62% for clavicula pro humero procedures, 83% and 70% for allograft arthrodeses, and 93% and 98% for soft tissue reconstructions. CONCLUSION: A stable construct is the treatment goal for shoulder reconstructions, as it enables effective function of the arm and hand.     

The reversed Delta shoulder prosthesis in reconstruction of the proximal humerus after tumour resection

The authors present two series of six and seven patients respectively, with a tumour of the proximal humerus, who were treated at two different institutions with a Delta type inverted shoulder prosthesis (DePuy International Ltd) after a Malawer type Ia or Ib resection. The rationale of using an inverted shoulder prosthesis is the aim to improve the functional outcome in rotator cuff deficient shoulders. This type of prosthesis medializes and lowers the centre of rotation, lengthens the lever arm of the deltoid muscle and improves its function. At one institution the resected part of the humerus was re-implanted after extracorporeal irradiation. It was fixed intramedullarly by cementation of the humeral prosthetic component to facilitate restoration of humeral height. This graft allowed reinsertion of muscles (deltoid, pectoralis, biceps) thus improving power generation postoperatively. The largest glenosphere, size 42, was routinely used to reconstruct the glenoid; this theoretically improves the functional outcome (increased external rotation) and stability. At the other institution no graft augmentation was used except in one patient. The height of the humeral prosthetic component was assessed after resection of the tumour by measurement of the resected part. The prosthetic stem was fitted in the remaining part of the humeral diaphysis, in three cases by cementation and in three cases by press-fit (hydroxyapatite coating). Muscle balance was appreciated intra-operatively. Stability of the prosthesis was directly related to the level of resection. Both techniques resulted in a minimum active abduction of 60 degrees, reaching 90 degrees or more in most patients. When compared to other results in the literature, this is a major functional improvement. The mean adjusted postoperative Constant score was 72.5% (range: 30-90%), and the mean MSTS score was 75.8% (range 36.7-96.7%).     

肩关节肿瘤切除和重建后的患肢功能观察

目的 肩关节肿瘤切除后,探讨不同重建方式的患肢长期功能。方法回顾性分析32例肩关节肿瘤保肢患者的临床资料。重建方式包括：8例一期肩关节融合,7例假体异体骨复合物,6例功能性间隔物,5例未行重建或悬吊术,3例假体,2例带血管蒂腓骨和1例异体骨。结果23例生存患者平均随访81个月。不同重建方式的功能评分分别为：一期肩关节融合为87％,主动运动优良,肩部有力;假体异体骨复合物为79％,间隔物为66％,未重建为85％,假体为60％和带血管蒂腓骨为73％。结论肩关节肿瘤的重建方式是根据切除范围和患者的实际需要来选择。如外展肌群无法重建,肩关节融合的功能良好,肩部有力;如果外展肌群可以重建,假体异体骨复合物功能较好。     

Functional outcomes and complications of reconstruction of the proximal humerus after intra‐articular tumor resection

Objective: To evaluate functional outcomes and complications of reconstruction of the proximal humerus after intra‐articular tumor resection. Methods: Twenty‐five patients who underwent Malawer I type resection and reconstruction of the proximal humerus for treatment of malignant or invasive benign tumors from August 1999 to August 2005 were evaluated. A variety of reconstructive procedures, including modular tumor prosthesis, osteoarticular allograft, and allograft‐prosthetic composite (APC), were performed after resection of tumor. Oncological and radiographic parameters were evaluated. The modified Musculoskeletal Tumor Society (MSTS) evaluation system was used to assess limb functional outcome. Results: The study group consisted of 10 male and 15 female patients, among which there were 20 malignant and 5 benign tumors. Restoration of shoulder function was achieved with a prosthesis in 6 patients, osteoarticular allograft in 12, and allograft‐prosthesis composite in 7. At a mean of 48 months follow‐up, 2 patients had died of disease. Two patients had local recurrence and 2 had metastatic disease. On the basis of the modified MSTS functional evaluation, the mean scores were 22.50 in the modular prosthesis group, 24.58 in the osteoarticular allograft group, and 27.00 in APC group, respectively. Joint instability and subluxation were serious complications affecting shoulder function in 10 patients. Conclusion: Reconstruction of the proximal humerus is an option that provides good relief of pain and preserves manual dexterity. Functional outcomes are better for APC and allograft than for modular prosthesis, due to retention of the rotation cuff. Complications in the APC group were less than in the allograft one.     

Evaluation of a reconstruction reverse shoulder for tumour surgery and tribological comparision with an anatomical shoulder arthroplasty

Purpose

The functional results after reconstruction of the proximal humerus in tumour surgery are poor. Therefore, a reversed proximal humerus replacement was developed in our institution (MUTARS humerus inverse). A low degree of wear on the polyethylene is required because of the patients’ youth and demands on shoulder function. A special type of polyethylene with shock-absorbing properties has been developed to minimise polyethylene wear in the MUTARS inverse proximal humerus replacement. We compared the tribological properties of an anatomical shoulder prosthesis (CAPICA) with the new reversed proximal humerus replacement (MUTARS humerus inverse).

Methods

Both prostheses were tested up to 5 × 10⁶ cycles. Every millionth cycle the surface was inspected and a gravimetric measurement was performed. A measurement of surface roughness was done before testing and after 5 × 10⁶ cycles.

Results

In both prostheses after 5 × 10⁶ cycles there were no major defects, such as delamination, observed. In the reversed proximal humerus replacement abrasion of 28 mg/10⁶ cycles was detected. The mean abrasion of the anatomical prosthesis was 9.28 mg/ 10⁶ cycles.

Conclusion

The glenoid component of the first reversed humerus replacement (MUTARS humerus inverse) has wear properties comparable to those of normal reversed shoulder prostheses. This is important, as this type of prosthesis is used in young patients after resection of bone tumours, with a good functional outcome. It can, therefore, be expected that the revision rate due to wear will be as high as in patients with normal reversed shoulder prostheses.     

An analysis of factors affecting the long-term results of total shoulder arthroplasty in inflammatory arthritis

The authors studied 36 patients undergoing 50 total shoulder arthroplasties for inflammatory arthritis with an average follow-up period of 5 years (range, 2-9 years). There were 7 men and 29 women. Twenty-nine patients (38 shoulders) had rheumatoid arthritis, 6 patients (11 shoulders) had systemic lupus erythematosus, and 1 patient (1 shoulder) had psoriatic arthritis. Twenty-four of the procedures were performed on the dominant hand. Twenty-one patients (32 shoulders) were receiving steroids, chemotherapeutic agents, or Gold therapy at the time of arthroplasty. Using the Hospital for Special Surgery scoring system, 22 shoulders had excellent, 18 good, 1 fair, and 9 poor results. Forty-eight of 50 shoulders had satisfactory pain relief. The average shoulder score was 85 points (range, 50-100 points). There were no reoperations, infections, or persistent nerve palsies and no symptomatically loose prostheses, although there were three cases of glenoid component shift. Eighteen glenoid components and 4 humeral components had radiolucent lines and in two cases metaphyseal bone atrophy was noted about the proximal humerus with firm cement fixation and bone hypertrophy about the stem tip. Total shoulder arthroplasty provides a predictable reconstructive alternative for patients with inflammatory arthritis. Overall functional results are related to the biologic condition and motivation of the patient, the status of the rotator cuff, and prosthesis alignment.     

The Tikhoff-Linberg procedure for bone tumors of the proximal humerus: the classical “extensive” technique versus a modified “transglenoid” resection

Summary The authors report on two groups of patients (each with 12) with primary bone tumors of the humerus who underwent either a classical Tikhoff-Linberg (T-L) procedure or a modified technique by which the body of the scapula was saved. The latter procedure was an en bloc resection of the glenohumeral joint after an extra-capsular osteotomy of the neck of the scapula, followed by reconstruction with a modular prosthesis. Indications, perioperative differences, and complications of both procedures are discussed. Besides producing better aesthetic and functional results, the modified technique offered the advantages of shorter anesthesia time, less blood loss, and a better anchorage of the prosthesis. The results of this study show that the proposed modification of the T-L procedure is indicated in patients with bone tumors of the proximal humerus in which invasion of the joint capsule is present without macroscopic involvement of the glenoid.Supported in part by Special Project Oncology, National Council for Research, grant no. 87.02810.44     

Use of the reverse shoulder prosthesis for the treatment of failed hemiarthroplasty in patients with glenohumeral arthritis and rotator cuff deficiency

We report the use of the reverse shoulder prosthesis in the revision of a failed shoulder hemiarthroplasty in 19 shoulders in 18 patients (7 men, 11 women) with severe pain and loss of function. The primary procedure had been undertaken for glenohumeral arthritis associated with severe rotator cuff deficiency. Statistically significant improvements were seen in pain and functional outcome. After a mean follow-up of 44 months (24 to 89), mean forward flexion improved by 26.4 degrees and mean abduction improved by 35 degrees . There were six prosthesis-related complications in six shoulders (32%), five of which had severe bone loss of the glenoid, proximal humerus or both. Three shoulders (16%) had non-prosthesis related complications. The use of the reverse shoulder prosthesis provides improvement in pain and function for patients with failure of a hemiarthroplasty for glenohumeral arthritis and rotator cuff deficiency. However, high rates of complications were associated with glenoid and proximal humeral bone loss.     

The Tikhoff-Linberg procedure: report of ten patients and presentation of a modified technique for tumors of the proximal humerus

The Tikhoff-Linberg resection is a limb-sparing surgical option to be considered for bony and soft-tissue tumors in and around the proximal humerus and shoulder girdle. Careful selection of patients whose tumor does not involve the neurovascular bundle in the axilla is required. The distal clavicle, upper humerus, and part or all of the scapula are resected. The tumor remains covered by the deltoid muscle plus portions of the muscles that arise from or insert into the resected specimen. In patients with tumors of the proximal humerus a custom prosthesis is used to maintain length and stabilize the distal humerus. Elbow flexion plus stability of the shoulder without the need of an orthosis may be achieved with muscle transfers. Function of the hand and forearm after Tikhoff-Linberg resection should be near normal. Review of results in 10 patients shows no local recurrences and excellent function. The major postoperative problem was nerve palsy. The Tikhoff-Linberg procedure should continue to be used for limb salvage in selected patients with tumors in or around the shoulder girdle.     

Pedicle screw system reconstruction in shoulder resection type IV-total scapulectomy: A case report and short term follow up

IntroductionShoulder resection remains a challenging procedure after scapulectomy for tumour resection. The results have various functional outcome, wound coverage, and cosmetic aspect. In this case report, we reported the outcome of pedicle screw application after scapulectomy procedure within 1 month follow up after surgical tumour excision.Case presentationA 74-year-old female presented with a painful lump on the left shoulder since nine months before admission. We performed physical examination, radiological evaluation using x-ray and MRI. We performed limb salvage surgery with shoulder girdle resection of tumour procedure using Malawer technique type IVB and applied pedicle and screw in proximal end clavicula and proximal end of humerus. We performed histopathological examination to ensure the tumour. We evaluated the patient one month after surgery using DASH score.DiscussionMRI examination revealed that there was a solid mass with malignant characteristic destructing left scapular bone with the acromioclavicular and glenohumeral joint involvement. We used pedicle and screw to reconstruct the patient with efficient cost spending consideration. Clinical valuation showed there was no pain left and hand-free movement except the limitation of shoulder abduction. DASH score evaluation pre operative and post operative showed improvement from 70.8 to 45.0.ConclusionLimb salvage procedure using pedicle screw system may be one of treatment of choice for treating tumour of the shoulder affecting glenohumeral joint with excellent result of evaluation both clinical and functional outcome.     

Functional recovery after a reverse prosthesis for reconstruction of the proximal humerus in tumor surgery

An alternative treatment for primary bone tumors of the proximal humerus was assessed. Four patients, who made full functional recovery after complete resection of the proximal humerus inclusive of the rotator cuff and subsequent reconstruction with a reverse shoulder prosthesis, were examined clinically and radiographically. Distinct medialization of the center of rotation of the glenohumeral joint (28 mm) and elongation of the remaining deltoid muscle (116%) were measured. Increased scapular rotation (118%) was observed. The radiologic results and thoracoscapular rhythm analyses were implemented in a three-dimensional computerized model of the glenohumeral joint. This allowed us to calculate a doubling of the moment of the deltoid abductor muscle in the true scapular plane. After tumor surgery, in which the proximal humerus is resected without reinserting the rotator cuff, full functional recovery of the shoulder can be obtained with a total shoulder prosthesis, medializing the glenohumeral center of rotation and elongating the remaining deltoid muscle. Level of Evidence: Therapeutic study, Level IV (case series-no, or historical control group).     

肩胛带骨肿瘤的外科治疗结果及评价

目的 探讨肩胛带骨肿瘤的手术切除方式、重建方法,观察术后功能恢复情况及临床结果.方法 回顾性分析1998年7月至2006年7月收治的71例肩胛骨周围骨肿瘤患者的病例资料,其中恶性肿瘤61例,骨巨细胞瘤10例.15例恶性肿瘤起源于肩胛骨,56例起源于肱骨近端.男42例,女29例;年龄11～62岁,平均36.5岁.手术方法:肩胛带离断术10例,单纯肩胛骨切除3例,肩胛骨切除、人工肩胛骨置换3例,部分肩胛骨及肱骨近端切除、假体置换8例,肱骨近端切除、假体置换47例.结果 10例骨巨细胞瘤患者肩周肌肉保留较好,术后MSTS功能评分平均28分.起源于肱骨近端的原发恶性骨肿瘤患者三角肌止点处均予以切除,术后肩外展30°～60°,MSTS功能评分平均23分.37例肱骨骨肉瘤患者中4例(10.8%)局部复发,2例骨转移,5例肺转移.7例转移患者均死亡.1例恶性骨巨细胞瘤患者出现肺转移死亡.3例尤文肉瘤患者出现肺转移死亡.5例肱骨及5例肩胛骨软骨肉瘤患者术后未见局部复发及转移.结论 肩胛带骨肿瘤切除、人工肱骨近端假体重建能保留完整肘部及手部功能、并发症少,是肩部恶性肿瘤的首选术式;肱骨近端骨肉瘤和下肢骨肉瘤比较预后较好;肱骨近端恶性肿瘤行关节内肿瘤切除和关节外肿瘤切除肿瘤的局部复发率接近,提示对多数肱骨近端恶性肿瘤可以采用关节内切除.     

Surface replacement of the humeral head in the rheumatoid shoulder

The clinical results obtained an average of 4.2 years after resurfacing of the humeral head in 72 rheumatoid shoulders showed 94% of the patients being pleased regarding pain relief and 82% reporting improved shoulder mobility. Shoulder function was significantly improved. The radiographs were analyzed regarding the position of the humeral head resurfacing cup, proximal migration of the humerus, and glenoid attrition during the follow-up period. Change of the distance between the superior margin of the cup and the greater tuberosity and/or change of inclination of the prosthesis were regarded as signs of prosthetic loosening. With that definition, 25% of the cups were found to be loose at follow-up. Prosthetic loosening, however, had no bearing on the clinical result. Also, no relationship was found between the position of the cup and the clinical outcome. Neither progressive proximal migration of the humerus in 38% of the shoulders nor central attrition of the glenoid in 22% of the shoulders showed any relationship to gain of mobility, pain relief, or functional ability.     

Secondary reconstruction of stumps above the elbow. Five cases

The authors report a serie of five patients with five stumps above the elbow who needed a secondary reconstruction to allow or facilitate a prosthesis. They used in the first case an expansion of the latissimus dorsi flap and of the axillary and prepectoral region in order to free the stump of the humerus sutured on the thorax. In the second case, a free parascapular flap covered an unstable scar of the clavicula after a scapulothoracic amputation. In the third case, the transfer of a free flap of fibula associated with a pedicled latissimus dorsi flap had allowed the elongation of the stump of the humerus. In the two last cases, a latissimus dorsi flap pedicled in one and free in the second one had allowed to preserved the length of the humerus for prosthesis. The technical choices are eclectic and different in every case. The purpose is to obtain an efficient trophicity and a thickness that can support the prosthesis and if possible a stump long enough to improve the adaptation of the prosthesis. The five operated patients were able to be apparated, reducing in this way their daily functional difficulties.     

Clinical evaluation of a new custom offset shoulder prosthesis for treatment of complex fractures of the proximal humerus

Primary hemiarthroplasty of the shoulder is an accepted procedure to treat complex proximal humeral fractures. The goal of this study was to assess the functional outcome in patients treated with hemiarthroplasty using a custom offset shoulder prosthesis, either for an acute four-part fracture of the proximal humerus or following failed primary treatment of a complex humeral fracture. Thirty seven patients were followed up for a mean of 17 months after shoulder replacement (Group A: four-part-fractures; n = 26, Group B: posttraumatic necrosis/non-union after failed primary treatment; n = 11). The Constant-Murley-Score and radiological score according to Neer's classification were used for postoperative functional and radiological assessment. Following hemiarthroplasty, Group A achieved an average Constant Score of 52 and Group B of 46. The pain relief after hemiarthroplasty was about 53% in Group A and only 33% in Group B. The least satisfying partial function was shoulder mobility in both groups. Radiographic evaluation did not correlate with the Constant Score. Patients secondarily treated with arthroplasty seem to have less chance to achieve a satisfying functional outcome compared to those with immediate hemiarthroplasty. These results emphasise the importance of a careful initial decision to select the most appropriate treatment modality in complex fractures of the proximal humerus.     

Modular endoprosthetic replacement for metastatic tumours of the proximal femur

Background and aims  

Endoprosthetic replacements of the proximal femur are commonly required to treat destructive metastases with either impending or actual pathological fractures at this site. Modular prostheses provide an off the shelf availability and can be adapted to most reconstructive situations for proximal femoral replacements. The aim of this study was to assess the clinical and functional outcomes following modular tumour prosthesis reconstruction of the proximal femur in 100 consecutive patients with metastatic tumours and to compare them with the published results of patients with modular and custom made endoprosthetic replacements.     

多发性骨髓瘤的外科治疗探讨

目的 探讨多发性骨髓瘤外科治疗的手术指征、方式和效果。方法 总结分析了29例孤立性骨髓瘤和多发性骨髓瘤患者的临床表现及外科治疗情况。本组病例男17例,女12例。年龄38～76岁,平均59．5岁。原发病灶位于脊柱9例,肋骨1例,眩骨2例,股骨上端2例,股骨干4例,骨盆5例,骶骨6例、这29例患者分别进行了下列外科治疗：行单纯病灶清除12例,其中6例为骶骨骨髓瘤,5例为骨盆部骨髓瘤;行脊柱前路病灶清除减压、钛网置入钢板内固定6例;行脊柱后路病灶清除减压,经椎弓根内固定3例;5例病理性骨折患者分别行肿瘤刮除、骨水泥填充,髓内钉或DHS内固定;3例患者行肿瘤切除,人工假体置换。文章评估了手术后疼痛、神经损害症状、脊柱不稳等症状的改善,生活质量及生存情况。结果 疼痛改善最明显,所有患者均有疼痛减轻。3例截瘫患者,一例由Frankal分级B级变为C级,2例由C级变为D级。术后平均随访1．5年。3例局部复发。结论 对有严重神经功能损害和严重影响患者生存质量的合并症的多发性骨髓瘤患者来说,外科手术治疗是一种有效可行的治疗方法,再结合化疗和放疗,对改善患者的生活质量和延长生存期是非常有意义的。     

肱骨近端恶性肿瘤的保肢治疗

目的 探讨肱骨近端恶性肿瘤切除术后的重建方法。方法 36例肱骨近端恶性肿瘤,其中骨肉瘤 11例、软骨肉瘤 6例、皮质旁骨肉瘤及纤维肉瘤各 3例、原始神经外胚层瘤及恶性纤维组织细胞瘤各 2例、转移性骨肿瘤 5例、恶性骨巨细胞瘤 4例。骨肉瘤、原始神经外胚层瘤与恶性纤维组织细胞瘤患者均接受了新辅助化疗。肿瘤关节内切除 33例,关节外切除 3例。 21例采用异体半关节移植, 4例采用人工假体置换, 6例行游离锁骨移植, 5例行带骨膜血管蒂锁骨移植。结果 随访 6～ 118个月,平均 62.7个月。死亡 11例,局部复发 3例。按 Enneking功能评价标准, 21例采用异体半关节移植的患者,平均得分 24分; 4例人工假体置换的患者,平均得分 26分; 11例采用同侧锁骨重建肱骨近端的患者,平均得分 23分。结论 肱骨近端恶性肿瘤保肢手术的重建以人工假体置换和异体半关节移植为首选,儿童的保肢可选用同侧锁骨移植。保肢术后的功能与肩袖和肩外展肌的修复密切相关。     

The scapulohumeral line revisited.

Routine observation of the scapulohumeral line in the true anteroposterior radiographic view of the shoulder will allow a higher level of confidence in ruling out posterior dislocation of the glenohumeral joint. It will also facilitate evaluation of the relationship between the proximal humerus and the scapula (especially the acromion and the glenoid fossa) in (1) abnormal conditions of the subacromial space; (2) fractures and dislocations of the proximal humerus; and (3) proximal humerus prosthesis insertion and assessment.