Effects and mechanisms of traditional Chinese medicines on functional dyspepsia: A reviewOA

Functional dyspepsia(FD) is a common and frequently occurring disease in clinic. With the infuence of environmental factors, social factors and dietary factors, the incidence rate of FD in the general population is yearly increasing. Traditional Chinese medicine has a long history and far-reaching infuence in the treatment of FD. It can prevent and treat FD in the form of multiple-components, targets and channels,with obvious effect and prominent advantages. This article starts with the common s...     

Therapeutic effects of Chinese herbal medicines for treatment of urolithiasis: A reviewOA

Urolithiasis is a common and complex disease of the urinary system, which can cause urinary tract blockage, urinary tract infection, and even damage to urinary system-related tissues. Although urolithiasis can be cured, its high recurrence rate and the development of chronic kidney disease in some patients have drawn the attention of nephrologists. Although the application of extracorporeal lithotripsy, percutaneous nephrolithotomy and other minimally invasive techniques have made the treatment ...     

Modulative effect of Physalis alkekengi on both gut bacterial and fungal micro-ecosystemOA

Objective: Gut microbiome is an intricate micro-ecosystem mediating the human health and drug efficacy. Physalis alkekengi(PAL) is an edible and time-honored traditional Chinese medicine. Several pharmacological effects of PAL have been verified and gut bacteria are implied in its therapeutic actions.However, the detailed modulation of PAL on gut bacterial species and on gut fungi remains largely unknown. We, therefore, designed a preliminary experiment in normal mice to reveal the modulation ef...     

Jianzhen's eastward sea-voyageOA

<正>Chunyu Jianzhen (688-763) was from the Jiangyang County,Guangling (now Yangzhou,Jiangsu Province).He was an eminent Buddhist monk and learned medical scientist of the Tang Dynasty(618-907).He is the author of Jianshen’s Secret Recipes (Jian Shang Ren Mi Fang).At the invitation of Japan,he went there and introduced Buddhism,medical and other technical knowledge to Japan,so he was honored by the Japanese people with the"Founder of Japanese Kampo Medicine"and"Master from Overseas".     

GUIDE FOR AUTHORSOA

<正>Introduction Types of paper Contributions falling into the following categories will be considered for publication: Original research papers, reviews, perspectives, news and views, case reports, letters.Please ensure that you select the appropriate article type from the list of options when making your submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.     

Antioxidant mechanism of modified Qiongyu paste against aging based on network pharmacology and experimental validationOA

Objective:To provide a possible basis for the anti-aging effect of modified Qiongyu paste(MQP).Methods:Ultra-high-performance liquid chromatography-Q-Orbitrap mass spectrometry was applied to confirm the effective components of MQP that we had identified from databases and research literature.Then,network pharmacology was employed to predict the possible underlying mechanism of MQP against aging.According to the overlap with age-related gene targets,we obtained key targets of MQP against aging u...     

GUIDE FOR AUTHORSOA

<正>Introduction Types of paper Contributions falling into the following categories will be considered for publication:Original research papers, reviews, perspectives,news and views, case reports, letters.Please ensure that you select the appropriate article type from the list of options when making your submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.     

GUIDE FOR AUTHORSOA

<正>Introduction Types of paper Contributions falling into the following categories will be considered for publication: Original research papers, reviews, perspectives, news and views, case reports, letters.Please ensure that you select the appropriate article type from the list of options when making your submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.     

GUIDE FOR AUTHORSOA

<正>Introduction Types of paper Contributions falling into the following categories will be considered for publication: Original research papers, reviews, perspectives, news and views, case reports, letters.Please ensure that you select the appropriate article type from the list of options when making your submission. Authors contributing to special issues should ensure that they select the special issue article type from this list.     

Instruction for AuthorsOA

<正>Chinese Herbal Medicines (CHM) is an official international journal sponsored by Tianjin Institute of Pharmaceutical Research and Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences.The purpose of CHM is to provide a forum for the studies on Chinese herbal medicines,phytomedicines,and natural products as well.The journal will accept the following contributions:letters,original articles,review papers,short communications,     

GUIDE FOR AUTHORSOA

<正>Introduction Types of paper Contributions falling into the following categories will be considered for publication:Original research papers,reviews,perspectives,news and views,case reports,letters.Please ensure that you select the appropriate article type from the list of options when making your submission.Authors contributing to special issues should ensure that they select the special issue article type from this list.Before You Begin Ethics in Publishing For information on Ethics in...     

Instruction for AuthorsOA

<正>Chinese Herbal Medicines(CHM) is an official international journal sponsored by Tianjin Institute of Pharmaceutical Research and Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences.The purpose of CHM is to provide a forum for the studies on Chinese herbal medicines,phytomedicines,and natural products as well.     

Effect of Rhei Radix et Rhizoma and Eupolyphaga Steleophaga on liver protection mechanism based on pharmacokinetics and metabonomicsOA

Objective: Based on metabonomics technology of high-performance liquid chromatography-mass spectrometry(HPLC-MS/MS) and hydrogen nuclear magnetic resonance spectroscopy(¹H NMR), the pharmacokinetic characteristics and therapeutic mechanism of Rhei Radix et Rhizoma(RhRR, Dahuang in Chinese), Eupolyphaga Steleophaga(EuS, Tubiechong in Chinese) combined with RhRR acting on acute liver injury were explored.Methods: Models of acute liver injury were established, and the pharmacokinetic met...     

A scoping review on traditional medicine for bruxismOA

Objective: To investigate the current evidence on traditional medicine in managing bruxism and its clinical efficacy.Methods: A search was conducted in nine databases to identify potential eligible articles published from the date of inception until August 3, 2022. All clinical studies that used traditional medicine of any type in treating bruxism were eligible for inclusion. Two authors performed data extraction and quality assessments independently. Retrieved data were tabulated and discussed ...     

Pu-erh tea: A review of a healthful brewOA

Pu-erh tea has been used for thousands of years to treat metabolic diseases. Recognized in Shen Nong’s Herbal Classic, a compendium kept by the first traditional Chinese practitioners, it is still highly valued for its hypocholesterolemic and hypolipidemic effects. This review reports the processing and bioactive components of pu-erh tea. Recent human and animal studies of pu-erh tea and its potential therapeutic mechanisms have also been summarized. The interaction of liver and gut microbiome r...     

Elucidation of the hepatoprotective effect and mechanism of Melastoma dodecandrum Lour. based on network pharmacology and experimental validationOA

Objective: To systematically explore the effect and mechanism of melastomatis dodecandri herba(Melastoma dodecandrum Lour.) in the treatment of hepatitis based on network pharmacology.Method: We evaluated the hepatoprotective effects of M. dodecandrum in concanavalin A(Con A)-induced hepatitis in mice by assessing survival rate, histological analysis, serum transaminases, and related cytokines. Then the mechanism of action was predicted by a network pharmacology-based strategy. Based on the resu...     

Characteristics of Xiao Chai Hu decoction based on randomized controlled trials: A bibliometric analysisOA

Objective: To explore the characteristics of Xiao Chai Hu(XCH) decoction in randomized controlled trials(RCTs) using a bibliometric method.Methods: Seven databases including PubMed, Web of Science, Embase, Cochrane library, China National Knowledge Infrastructure(CNKI), Chinese Scientific Journal Database(VIP) and Wanfang database were retrieved from inception to May 27, 2022. In the study, XCH decoction(or modified) used alone or combined with conventional Western medicine as an intervention me...     

Chemical composition and pharmacological activity of seco-prezizaane-type sesquiterpenesOA

The seco-prezizaane-type sesquiterpenes(SPS), as a special class of sesquiterpenes with a highly oxidative five-ring cage structure and seven consecutive chiral centers, are isolated from the genus Illicium,which have a variety of biological activities, including neurotoxicity and neurotrophic effects, etc. This review summarizes the chemical constituents and pharmacological effects of SPS, and discusses the potential trend and scope of future research.     

Natto: A medicinal and edible food with health functionOA

Natto is a soybean product fermented by natto bacteria. It is rich in a variety of amino acids, vitamins,proteins and active enzymes. It has a number of biological activities, such as thrombolysis, prevention of osteoporosis, antibacterial, anticancer, antioxidant and so on. It is widely used in medicine, healthcare food, biocatalysis and other fields. Natto is rich in many pharmacological active substances and has significant medicinal research value. This paper summarizes the pharmacological a...     

Discovery of the relationship between bitter taste and bitter flavor(efficacy) based on hTAS2RsOA

Objective: To explore the relationship between bitter taste and bitter flavor(efficacy), their characteristics were analyzed at the target and pharmacodynamic points.Methods: Compounds with bitter receptor activity were obtained by high-throughput screening models of the human bitter taste receptors(h TAS2Rs), which were used to analyze bitter taste. The efficacy of anti-asthma medications was used as an example to research bitter flavor(efficacy). The pharmacological effects of bitter taste and...