国外旋毛虫病的流行现状

该文对近年来人体旋毛虫病在国外的地理分布、流行现状、感染来源、流行因素、传播途径及发病季节等进行了综述。     

亚洲国家旋毛虫病的流行历史与现状

在亚洲48个国家中,11个(22.92%)的家养动物有旋毛虫感染,14个(29.17%)存在有野生动物的旋毛虫感染,18个(37.5%)有人体旋毛虫病的报道.该文对旋毛虫病在亚洲国家的地理分布、流行历史与现状、感染来源及致病虫种等进行了综述.     

墨西哥及南美洲旋毛虫病流行的历史和现状

该文对旋毛虫病在墨西哥及南美洲的历史、分布、流行现状、感染来源、致病虫种、检疫方法及防治措施等进行了综述。     

俄罗斯及东欧国家旋毛虫病的流行状况

该文对旋毛虫病在俄罗斯及部分东欧国家(波兰、斯洛伐克等)的地理分布、流行状况与趋势、感染来源及致病虫种等进行了综述。     

大理地区近10年旋毛虫病流行情况报道

目的 了解大理地区近10年来旋毛虫病的流行情况。方法 对1992－2001年门诊患者资料，进行整理、分析。结果 最近10年，在1342例门诊可疑病人中，检出旋毛虫抗体阳性669例，阳性率达49．9％，男性高于女性，血常规检查：有部分白细胞及嗜酸性粒细胞升高。附一起暴发流行报告。结论 大理地区旋毛虫病感染较重，并且呈逐年上升趋势，偶有暴发流行。     

国外旋毛虫病的流行现状

该文对近年来人体旋毛虫病在国外的地理分布、流行现状、感染来源、流行因素、传播途径及发病季节等进行了综述.     

许昌市旋毛虫病流行病学调查

１９９６ ～１９９７ 年,分别在河南省许昌市的许昌县及鄢陵县进行人群及动物旋毛虫病流行病学调查。结果发现家猪旋毛虫感染率为２ ．６１％ 。血清学检查,家猪、家鼠及人旋毛虫抗体阳性率依次为５ ．４５ ％ ,６ ．６１％ 和４ ．８５ ％ ;汉民血清的阳性率（８ ．８２ ％ ） 高于回民（０ ．９６％ ）。对同１ 份家猪肌肉标本采取直接压片法、人工消化法及血清学抗体检测３ 种方法检查,发现直接压片法容易漏检,人工消化法及血清学抗体检测法的检出率较高。提示目前当地取上市猪肉膈肌直接压片镜检旋毛虫检疫方法亟待改进。为不漏检,建议对猪肉上市前检疫时先用血清学试验初筛,对检出阳性者再用人工消化法确证。     

大理地区近10年旋毛虫病流行情况报道

目的了解大理地区近 1 0年来旋毛虫病的流行情况。方法对 1 992 -2 0 0 1年门诊患者资料 ,进行整理、分析。结果最近 1 0年 ,在 1 34 2例门诊可疑病人中 ,检出旋毛虫抗体阳性 6 6 9例 ,阳性率达 4 9.9% ,男性高于女性 ,血常规检查 :有部分白细胞及嗜酸性粒细胞升高。附一起暴发流行报告。结论大理地区旋毛虫病感染较重 ,并且呈逐年上升趋势 ,偶有暴发流行。     

旋毛虫病的免疫预防研究

至目前为止，有关猪旋毛虫病免疫预防的研究甚少。对旋毛虫各期虫体抗原的免疫原性虽已有人分别作过一些研究，但仍未见３期虫体抗原对家猪免疫保护作用在同一实验中对比观察的报道及其混合抗原对家猪免疫作用的研究报道。本实验观察了用旋毛虫各期虫体抗原及其混合抗原免疫家猪后其对攻击性感染的免疫保护作用。     

The epidemiology of human trichinellosis in China during 2000-2003

The endemic foci of trichinellosis continue to be mainly located in the southwestern, the central and northeastern China. The seroepidemiological surveys of T. spiralis infection in humans were carried out in six Provinces or Municipals (P/M) of China during 2000-2003, the overall seroprevalence was 3.57%. From 2000 to 2003, 17 outbreaks of human trichinellosis, with 828 cases and 11 deaths, were recorded in 8 P/A of China. All of 11 deaths occurred in the southwestern China (1 case in Sichuan, 4 cases in Tibet and 6 cases in Yunnan), where the ethnic groups have the habit of eating raw meat. Pork is the predominant source of outbreaks of human trichinellosis in China. Out of 17 outbreaks, 13 (76.47%) outbreaks were caused by eating raw or poorly cooked pork, 2 (11.77%) outbreaks caused by eating raw dog meat and 2 (11.77%) outbreaks by eating game meat (wild boar and bear), suggesting the increasing significance of dog and game meat as source of infection for human trichinellosis. The partial effects of health education interventions for control of trichinellosis have been achieved in some counties of Yunnan province. The number of inhabitants eating raw meat has decreased from 72.74% (1561/2146) before interventions to 47.43% (489/1031) after interventions. The decrease of incidence of trichinellosis in China during the past 4 years was probably due to a combination of factors, including the reduction in the prevalence of Trichinella infection in domestic swine, the strengthened meat inspection, the increased use of home freezers and the development of heath education practice.     

我国旋毛虫病流行病学 诊断 治疗及防治措施研究进展

旋毛虫病是一种呈世界性分布的人兽共患寄生虫病,人和多种动物（包括肉食动物、草食动物甚至某些禽鸟类）均可被感染,人因生食或半生食含有活幼虫囊包的肉类或肉制品而感染。在中国,该病主要流行于西南、东北和中原地区,危害人数多、社会影响大。该病暴发所导致的突发性公共卫生事件,严重威胁着人民健康和社会稳定。本文就我国旋毛虫病流行状况、诊断、治疗和防控措施等作一概述,旨在为进一步做好我国旋毛虫病防治工作提供参考。     

人群及猪旋毛虫病血清流行病学调查

目的 了解流行区和非流行区人群和(或)猪旋毛虫病血清的流行情况,为流行区制定旋毛虫病防治策略及措施提供依据.方法 从流行区云南洱源和勐海县抽取6个行政村,从非流行区上海市和吉林省延吉市各选1个居民小组,对人群和(或)猪旋毛虫病进行血清流行学调查,采用ELISA法检测人群、猪血清IgG抗体,压片镜检猪肌肉.对被采血人员进...     

我国旋毛虫病的流行趋势

该文对我国旋毛虫病的流行趋势进行了分析.西南地区(云南、四川及西藏)是目前我国旋毛虫病的主要流行区,西部地区(青海、内蒙古等)有可能成为新的流行区.我国已发生输入性旋毛虫病的暴发,且在边境口岸入境肉类中已检出旋毛虫.旋毛虫病暴发主要发生在冬季,猪肉是主要的传染源,旋毛虫感染猪主要来自小养猪场和散养的猪,野生动物肉类也是重要的传染源.我国旋毛虫病防治工作的重点应放在西南地区.     

旋毛虫病免疫学诊断研究进展

旋毛虫病（trichinellosis）是一种危害严重的人畜共患寄生虫病,人因食入生的或不熟的含活幼虫囊包的肉类及其制品而感染.肌肉活检是该病确诊的依据,但是受摘取组织局限性的影响,不易检出幼虫,容易漏诊.免疫学诊断技术常常作为检测重要的辅助手段.该文概述了酶联免疫吸附试验、凝集试验、免疫酶染色试验、间接荧光抗体技术、快速免疫层析法、斑点免疫金渗滤法酶联免疫电转移印记技术等7种旋毛虫病免疫学诊断的抗体检测方法和1种抗原检测方法,并对早期、快速、准确诊断旋毛虫病的检测方法进行分析评价.     

Characterization of a Trichinella spiralis 31 kDa protein and its potential application for the serodiagnosis of trichinellosis

The Trichinella spiralis 31 kDa protein (Ts31) was screened from the excretory-secretory (ES) proteins of muscle larvae (ML) by immunoproteomics using serum from mice infected with T. spiralis at 18 days post infection (dpi). The aim of this study was to characterize the Ts31 protein and to evaluate the potential of the recombinant Ts31 protein (rTs31) for serodiagnosis of human trichinellosis. Ts31 gene was cloned and rTs31 was produced in an E. coli expression system. An anti-rTs31serum recognized the native protein migrating in a 25–55 kDa range by Western blotting of ML crude or ES antigens. Expression of Ts31 gene was observed at all developmental stages of T. spiralis (adult worms, newborn larvae, pre-encapsulated larvae and ML). An immunolocalization analysis identified Ts31 in the cuticle and stichocytes of the parasite. The sensitivity of rTs31-ELISA and ES antigen ELISA for detecting anti-Trichinella IgG antibodies in sera of patients with trichinellosis was 97.83% (45/46) and 86.78% (39/46), respectively (P > 0.05); The specificity of rTs31-ELISA was 99.13% (114/115), which was significantly higher than 85.22% (98/115) of ES antigen ELISA (P < 0.01). The rTs31 protein of T. spiralis could be considered as a potential diagnostic antigen for trichinellosis.