激素替代疗法对妇女绝经期症状与子宫及其循环的影响

目的；观察激素替代疗法对妇女绝经期症状，子宫及其循环的影响。方法；３０例病人分２且，使用以及口服雌激素前后，观察子宫体积，内膜厚度；Ｋｕｐｐｅｒｍａｎ评分，血清Ｅ２、ＦＳＨ、彩超油子宫动脉博动指数及阻力指数；用Ｔ检验统计，结果；用雌服地激素后，Ｋｕｐｐｅｒｍａｎｙ评分，ＦＳＨ下降，口服绥改善血脂构成。结论：激素替代闻 法可改善绝经期期症状，降低子宫循环阻力，增加子宫血供；口服者可改善血脂构成。     

激素替代疗法治疗更年期综合征的临床观察

大部分妇女在更年期被一系列或轻或重的症状所困惑 ,这些症状统称为更年期综合征。这是由于卵巢功能衰退 ,体内激素水平波动或下降所致的以植物神经功能紊乱为主 ,伴有神经心理症状的一组症候群[1] 。我们应用醋酸甲羟孕酮复合胶囊(商品名 :妇更春胶囊 )治疗更年期综合征 ,观察并探讨该药对治疗更年期症状的效果及副作用。1　资料和方法1 1　对象 :选自 2 0 0 0年 1月～ 2 0 0 2年 6月来我院就诊的更年期综合征患者 3 0例。其中年龄最大 65岁 ,最小 3 5岁 ,平均 5 2岁。经过询问病史 ,均有不同程度更年期症状。体检及辅助检查血雌二醇 (E2 …     

激素替代疗法治疗妇女更年期综合征53例临床观察

目的探讨更年期综合征妇女激素替代治疗（HRT）相关指标的变化及其临床意义。方法本文对53例更年期综合征患者行激素替代疗法治疗。结果治疗后患者的各项激素及生化指标与治疗前比较,雌二醇（E2）、孕激素（P）明显升高;而卵泡刺激素（FSH）、黄体生成素（LH）、碱性磷酸酶（AKP）、总胆固醇（TC）及甘油三酯（TG）等指标均明显降低,且差异具有统计学意义（P〈0．05）,这表明HRT能够调节更年期妇女的体内激素水平,对绝经期及绝经后期妇女的心血管有保护作用。结论采用HRT法治疗妇女更年期症状是安全的,但是否选用HRT还需要掌握激素使用的适应证、禁忌证和慎用情况。     

不同剂量激素补充对围绝经期妇女更年期综合征的影响

目的探讨不同剂量激素补充对围绝经期妇女更年期综合征的影响。方法选取2011年6月-2012年6月永州市江华县人民医院收治的142例围绝经期妇女,分为低剂量组（91例）和常规剂量组（51例）,分别给予0．3mg和0625mg雌激素治疗,观察两组治疗效果。结果两组患者更年期综合征改善情况比较,差异无统计学意义;低剂量组不良反应发生率低于常规剂量组,差异有统计学意义（P〈0.05）。结论低剂量激素补充疗法可有效改善围绝经期妇女更年期综合征症状,且安全性较好,值得临床推广应用。     

更年期女性补充营养应坚持七多三少

女性在步入更年期后,由于卵巢功能的下降导致其体内雌激素水平降低,容易患上更年期综合征、骨质疏松症以及心脑血管病等疾病。因此,更年期女性除了要通过药物进行治疗以外,还需要补充各种营养来增强体质,改善更年期症状以及辅助治疗各种更年期疾病。为此,美国著名医学网站网络博士(WebMD)为更年期女性正确地补充营养推荐了一套七多三少的饮食指导方针,下面我们就介绍一下此方针的具体内容,以供处在更年期的女性参考。     

Complementary and alternative medicine in the treatment of menopausal symptoms

A large number of women will pass through menopause each year. Women in menopausal transition experience a variety of menopausal symptoms. Although hormonal therapy remains the most effective treatment,side effects have been reported by several large studies.An increased number of women seek the use of complementary and alternative medicine(CAM) for treating menopausal symptoms.This review analyzes the evidence from systematic reviews,randomized controlled trials and epidemiological studies of using herbal medicine(Black cohosh, Dong quai,St John’s wart,Hops,Wild yam,Ginseng,and evening primrose oil) and acupuncture for the treatment of menopausal symptoms.Evidence supporting the efficacy and safety of most CAM for relief of menopausal symptoms are limited. Future larger and better controlled studies testing the effectiveness of these treatments are needed.     

A survey of complementary and alternative medicine in Iran

Objective:To survey the use,capability and satisfaction of complementary and alternative medicine(CAM)in comparison with conventional medicine in Iran.Methods:In this national survey,a cross-sectional study was designed,5,000 people were surveyed to identify predictors of Iranian traditional medicine(ITM)use compared with conventional medicine.Data were collected through a questionnaire that covered three different predictor categories: demographic information,patient’s viewpoint,and patients’ experiences.Results: Most of the participants preferred government owned hospitals rather than other places.Praying for one’s own health was the most frequent and favorable ITM domain(P=0.017)based on patients’ interests,both in low-(P=0.08)and highlevel (P=0.011)educated subjects.Among the participants,97.8%had previous conventional medicine history due to their chronic diseases Conclusions:Iranian patients resort to ITM as a choice at the late stage of the disease.Current deficiency in integration of CAM and conventional medicine is in contrast to the increasing demand on patients’ side.Health care organizers should be facilitating the CAM services by tuition of CAM practitioners and supporting eligible CAM centers for diagnosis and treatment of patients.     

Action mechanisms of complementary and alternative medicine therapies for rheumatoid arthritis

Rheumatoid arthritis(RA) is characterized as a chronic inflammatory disease in joints and concomitant destruction of cartilage and bone.Cartilage extracellular matrix components,such as typeⅡcollagen and aggrecan are enzymatically degraded by matrix metalloproteinases(MMPs) and aggrecanases in RA.Currently,treatments targeting cytokines,including anti-tumor necrosis factor (TNF)αantibodies,soluble TNF receptor,anti-interleukin(IL)-6 receptor antibody, and IL-1 receptor antagonist,are widely used for treating RA in addition to anti-inflammatory agents and disease-modifying antirheumatic drugs(DMARDs),such as methotrexate,but these treatments have some problems,especially in terms of cost and the increased susceptibility of patients to infection in addition to the existence of low-responders to these treatments.Therefore,therapeutics that can be safely used for an extended period of time would be preferable.Complementary and alternative medicines including traditional Chinese medicines(TCM) have been used for the arthritic diseases through the ages.Recently,there are many reports concerning the anti-arthritic action mechanisms of TCM-based herbal formulas and crude herbal extracts or isolated ingredients.These natural herbal medicines are thought to moderately improve RA,but they exert various actions for the treatment of RA.In this review,the current status of the mechanism exploration of natural compounds and TCM-based herbal formulas are summarized,focusing on the protection of cartilage destruction in arthritic diseases including RA and osteoarthritis.     

中医药辅助替代治疗在卵巢缺失综合征中的运用

目前,妇科恶性肿瘤术后造成的卵巢缺失综合征不仅影响女性的生活健康,而且引发一系列的社会问题.常规药物治疗对卵巢缺失综合征的疗效较为有限,而中医药补充替代治疗通过补充替代和代谢调节,不仅协同手术、西药的治疗作用,减少西医西药对人体的损害,而且经济实用,减轻肿瘤患者的精神及经济负担,同时中医药绿色疗法,回归自然,亦是创造医疗和谐的保障.     

补充替代医学国际使用情况分析

中医药属于世界补充替代医学的重要组成部分，把握补充替代医学的国际形势以及中医药在其中的地位是中医药国际化的基础。本文通过分析国际社会补充替代医学的使用率、应用病种、使用者的社会人口学特征以及医学经济学情况等，探索提升中医药在海外的声誉和使用率的可行途径。     

Cancer complementary and alternative medicine research at the US national cancer institute

The United States National Cancer Institute(NCI) supports complementary and alternative medicine(CAM) research which includes different methods and practices (such as nutrition therapies) and other medical systems(such as Chinese medicine). In recent years,NCI has spent around $120 million each year on various CAM-related research projects on cancer prevention,treatment,symptom/side effect management and epidemiology.The categories of CAM research involved include nutritional therapeutics, pharmacological and biological treatments,mind-body interventions,manipulative and body based methods,alternative medical systems,exercise therapies,spiritual therapies and energy therapies on a range of types of cancer.The NCI Office of Cancer Complementary and Alternative Medicine(OCCAM) supports various intramural and extramural cancer CAM research projects.Examples of these cancer CAM projects are presented and discussed.In addition,OCCAM also supports international research projects.     

马里兰大学医学院结合医学中心——美国医学院最早成立的替代医学中心

马里兰大学医学院的补充医学中心成立于1991年,是美国在西医学院成立的第一个以研究中医药为主的综合性补充和替代医学中心。从1995年起连续被美国国家健康研究院评为全国中医研究的杰出中心,研究主要集中在评估中医药、针灸和身心疗法如气功、冥想疗法的安全性、有效性及作用机制。补充医学中心作为马里兰大学的交叉学科中心,主要承担了科研、临床、文献和教育4个方面的工作,彼此促进,已形成一个充满凝聚力的团队。中心近年来还增加了针灸和中医药研究在国际间的交流合作,特别与中国的香港中文大学、上海中医药大学和其他中医药大学进行了合作。     

Remifemin与替勃龙治疗围绝经期综合征的临床比较

目的:与替勃龙比较观察Remifemin治疗我国妇女围绝经期综合征的有效性和安全性.方法:选取244例符合入选标准的受试者随机分成Remifemin组(试验组)和替勃龙组(对照组),通过随机、双盲、平行对照研究比较两组的Kupperman评分,Kupperman评分反应率和不良事件发生率.结果:Kupperman评分与不良事件频数复合变量的非劣效检验P＜0.0001,有统计学意义,Kupperman评分,Kupperman评分反应率两组组间比较P＞0.05,无统计学意义,不良反应事件两组组间比较P＜0.001,有极显著统计学意义,说明Remifemin的疗效非劣于替勃龙,安全性优于替勃龙.结论:Remifemin治疗我国妇女围绝经期综合征是安全有效的.     

美国补充替代医学的科研现状及其与中国中医药研究的比较

美国对包括中医药在内的补充替代医学的研究日益关注。研究规模与投入不断增加。中医疗法的偏重、东西方知识背景、思维方式以及对中医理论认可程度的不同导致中国和美国在中医学研究的内容和思路上存在差异。     

Evidence-based practice method of integrative Chinese and Western medicine based on literature retrieval through PICO question and complementary and alternative medicine topics

An evidence-based practice method according to literature retrieval through PICO （Patients,Intervention,Comparison,Outcome） questions and complementary and alternative medicine （CAM） topics,which can obtain helpful evidence for guiding clinical practice,was introduced with a practical example in this paper.The knowledge of diseases and Western medicine treatment can be acquired by literature retrieval through PICO question,while searching by CAM topics may provide evidence for Chinese medicine （CM）.Thus the author held that literature retrieval through both PICO question and CAM topics was an ideal evidencebased practice method for integrative Chinese and Western medicine （ICWM）.However,since the standard in CM evidence hierarchy is still under study,the value of the CAM thematic retrieval method remains very limited.In the future,studies on the definition and hierarchy of CM evidences and the herb-drug interaction between Western and Chinese medicine during a combination therapy should be strengthened to improve the status of ICWM evidence-based practice.