中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

血清高敏C反应蛋白水平与五年累积糖尿病发病风险的关系

目的 研究高敏C反应蛋白(hs-CRP)与5年糖尿病发病风险的关系.方法 研究对象来源于"中国多省市心血管病前瞻性队列研究"中的北京大学社区队列.2002年对该队列45～74岁1541人进行心血管病危险因素调查和hs-CRP水平测定,2007年进行危险因素复查,对两次资料完整且基线无糖尿病和感染性疾病的1045人进行分析.结果 研究人群5年间糖尿病的年龄标化累积发病率为8.8%,男性为9.8%,女性为8.2%.基线hs-CRP水平四分层后显示:男女两性糖尿病的累积发病率均有随hs-CRP水平升高而逐渐增加的趋势(P＜0.01).调整基线年龄、高血压、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、甘油三酯、血糖、吸烟和腹部肥胖后,男女两性中hs-CRP≥3mg/L者发生糖尿病危险分别是hs-CRP＜1 mg/L者的3.30倍(95%CI:1.25～8.73)和2.58倍(95%CI:1.06～6.29).男女两性基线hs-CRP水平判定糖尿病是否发病的ROC曲线下面积分别为0.619(95%CI:0.536～0.701)和0.667(95%CI:0.585～0.749).结论 基线hs-CRP水平是糖尿病发病的独立预测因素,提示慢性炎症在糖尿病发生的病理过程中发挥重要作用.

Abstract：

Objective To analyze the association between hs-CRP(high-sensitivity C-reactive protein) levels in serum and the 5-year-accumulative-risk of diabetes in a general population.Methods Participants were from the cohort of Peking University residential community in the Chinese Multi- provincial Cohort Study(CMCS). Two surveys on cardiovascular risk factors and the measurements of serum hs-CRP levels were conducted in 2002 and 2007, respectively. Individuals with incomplete information and those having infectious diseases at baseline were excluded. A total of 1045 participants aged 45 to 74 years and free of diabetes at baseline were included in this analysis.Results The age-standardized 5-year accumulative incidence rate of diabetes was 8.8% (male:9.8%, female: 8.2% ) and increased significantly with the level of hs-CRP in both women and men (P＜0.01). After adjustment for age, hypertension, low-density liproprotein cholesterol, and high-density liproprotein cholesterol, triglycerides, fasting glucose, smoking status and central obesity,people with hs-CRP≥3 mg/L had a 3.30 times higher risk of developing diabetes in men and 2.58 times for women when compared to those with hs-CRP＜1 mg/L. The areas under the receiver operating characteristic curves of baseline hs-CRP level in predicting the incidence of diabetes were 0.619(95%CI:0.536-0.701 ) in men and 0.667(95%CI:0.585-0.749) in women. Conclusion Serum hs-CRP levels could predict the incidence of diabetes, indicating that inflammation might have great importance in the onset of diabetes.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

中国成年人高血压患病区域聚集性及危险因素的多水平模型分析

Objective To analyze the region cluster and risk factors of hypertension in the Chinese adult population and to explore the application of multilevel regression model in the risk factors of hypertension. Methods Multi-stage random sampling technique was used to choose 15 540 individuals aged 35-74 years from 10 regions in China. Two-level logistic regression models were fitted under MLwiN 2.02 software. Results The region cluster of hypertension existed and variance portion coefficient was 3.1%. After adjusting for the age and gender, overall obese people (BMI≥28 kg/m2) were 4.50(95%CI: 4.00-5.06) times, overweight people (BMI=24-27.9 kg/m2) were 2.26 (95%CI: 2.07-2.46) times more likely to be hypertensive as compared with those of normal BMI (18.5-23.9 kg/m2), and those centrally obesive people (Waist circumference≥85 cm in male or 80 cm in female) were 2.62 (95%CI: 2.42-2.83) times more likely to be hypertensive as compared with those of normal WC. The age-and gender-adjusted odds ratios (Ors) of triglyceride (TG), serum total cholesterol (TC), glucose, low-density lipoprotein cholesterol (LDL-C) , high-density lipoprotein cholesterol (HDL-C) and drinking alcohol were 2.10 (95% CI: 1.89-2.33) , 2.08 (95% CI: 1.84-2.35) , 1.85 (95% CI: 1.60-2.14) , 1.58 (95% CI: 1.38-1.81), 1.49(95%CI: 1.32-1.69) and 1.15(95%CI: 1.05-1.27), respectively. Conclusion The prevalence of hypertension was not only affected by individual risk factors, such as obesity, drinking alcohol, abnormal glucose and serum lipids profile, but also affected by the geographic environment where people resided in. Population-and risk factors targeted strategies, proved a promising way to reduce individual risk of hypertension in the primary prevention of hypertension.     

天津市宝坻区老年人体质指数、腰围以及腰围身高比与高血压患病率的关联

  目的   探讨天津市宝坻区60岁及以上老年居民的体质指数(body mass index, BMI)、腰围(waist circumference, WC)以及腰围身高比(waist-to-height ratio, WHtR)与高血压患病率的关联。   方法   本研究对2018年4-5月参加天津市宝坻区口东卫生院体检的老年人(≥60岁)进行问卷调查和体格检查。采用分层分析和logistic回归分析BMI与WC(或WHtR)对高血压的联合作用和交互作用。   结果   共邀请1 692人, 1 417人(83.75%)参与本研究。老年人群的高血压患病率为46.36%、BMI超重和肥胖者占66.50%、WC中心型肥胖者占74.66%、WHtR超重和肥胖者占75.38%。与BMI或WC正常相比, BMI超重(OR=1.65, 95% CI:1.19~2.30)和肥胖(OR=3.41, 95% CI:2.23~5.20)及WC中心型肥胖(OR=1.49, 95% CI:1.00~2.23)均增加高血压的患病风险。BMI联合WC超重/肥胖(OR=2.49, 95% CI:1.78~3.46), 或BMI联合WHtR超重/肥胖(WHtR超重: OR=2.05, 95% CI:1.41~2.99;WHtR肥胖: OR=2.37, 95% CI:1.50~3.76)的患病风险高于后者单独作用的风险(WC超重/肥胖: OR=1.39, 95% CI:0.90~2.15;WHtR超重: OR=1.02, 95% CI:0.62~1.66;WHtR肥胖: OR=1.44, 95% CI:0.55~3.81)。   结论   三项指标中, BMI与高血压患病的关联性最强, 且BMI超重/肥胖增强WC(或WHtR)与高血压的关联, 提示控制BMI相关体重指标在正常范围内有助于预防和控制高血压。     

中国成年人体质指数和腰围与高血压关系的四年随访研究

目的探讨中国成年人体质指数(BMI)和腰围(WC)的增加与高血压发病危险的关系。方法利用“中国居民健康与营养调查”资料,以4552例18~60岁参加2000年调查、当时无高血压等慢性病并且2004年调查被随访到者为研究对象,考察基线BMI和WC对高血压的预测作用,以及BMI和WC4年间的变化与高血压发病之间的关系。结果男性和女性随访4年高血压发病率分别为20.01%和13.52%。随着基线肥胖程度的增加,高血压的发病危险增加。与BMI和WC均不肥胖者相比,BMI超重/肥胖并且WC肥胖者发生高血压的危险最高(男性,RR=2.840,95%CI:2.139~3.771;女性,RR=2.734,95%CI:2.050~3.647)。调整了其它协变量后,4年中BMI每增加一个单位,男性和女性患高血压的危险分别增加0.141和0.109倍;WC每增加1cm,男性和女性患高血压的危险分别增加0.038和0.035倍。结论体质指数和腰围的增加均能增加高血压发病的危险,体质指数和腰围联合使用可增强对高血压发病的预测作用。     

江苏省成年居民肥胖与高血压相关关系研究

目的 探讨不同体型人群中超重肥胖、中心性肥胖与高血压患病率、知晓率、治疗率、控制率、治疗控制率相关关系。方法 采用整群随机抽样,对江苏省成年居民进行横断面调查,采用t检验、F检验分析组间差异;采用χ2检验,logistic回归模型计算OR值及95％CI。结果 江苏省成年居民BMI≥24/中心性肥胖率高达47.6%。BMI≥24/中心性肥胖人群的高血压患病率、知晓率、治疗率分别为51.2%、60.6%、54.3%,均高于其他体型人群。BMI＜18.5/非中心性肥胖人群的高血压治疗控制率最高,为60.0%。Logistic 回归分析结果表明,在调整年龄、收入、文化程度及吸烟饮酒状况后,与BMI = 18.5～23.9/非中心性肥胖相比,BMI≥24/中心性肥胖的人群高血压患病风险增加3.111倍（aOR = 3.111,95%CI = 2.665～3.632）。BMI = 18.5～23.9/中心性肥胖人群以及BMI≥24/中心性肥胖人群高血压治疗控制不良风险显著增加,调整OR值分别为0.362（95%CI = 0.155～0.845）和0.579（95%CI = 0.394～0.851）。结论 江苏省成年居民BMI≥24/中心性肥胖率较高,且高血压患病风险最高,中心性肥胖增加高血压治疗控制不良的风险。     

Non-obese (body mass index < 25 kg/m2) Asian Indians with normal waist circumference have high cardiovascular risk

OBJECTIVE: Although the prevalence of obesity is not high in Asian Indians, increased prevalence rates of metabolic perturbations and cardiovascular risk factors have been reported. In this study, we evaluated body mass index (BMI), anthropometric measurements, and body fat profiles of obese and non-obese subjects and correlated those values with cardiovascular risk factors. METHODS: This cross-sectional study involved 639 subjects (170 men and 469 women) from low socioeconomic stratum residing in urban slums of New Delhi. Non-obese subjects were categorized into quartiles of percentage of body fat (%BF) and waist circumference (WC). Using logistic regression analysis, the odds ratios (ORs) and 95% confidence intervals (CIs) for the occurrence of cardiovascular risk factors (diabetes mellitus [DM], hypertension, hypercholesterolemia, hypertriglyceridemia, low levels of high-density lipoprotein cholesterol, and high levels of low-density lipoprotein cholesterol) were computed with first quartile in the non-obese group as the reference category for the following five categories: %BF and WC quartiles in the non-obese group and obese group (BMI > or = 25 kg/m(2)). RESULTS: In the non-obese group, approximately 66% of men and 88% of women had at least one risk factor. In non-obese women, significantly high ORs and 95% CIs were found for hypertension (3.2, 1.4-7.2), DM (2.8, 1.2-6.3), and hypertriglyceridemia (3.9, 1.9-8.3) in the upper quartiles of %BF, and significantly high OR (95% CIs) was observed for hypertriglyceridemia (3.9, 1.4-10.8) in non-obese men. Among non-obese men, significantly high OR (95% CIs) was found for hypertriglyceridemia (3.2, 1.0-10.3); among non-obese women, significantly high ORs (95% CIs) were observed for hypertension (2.5, 1.1-5.8) and hypertriglyceridemia (2.5, 1.2-5.2) in the normal range of WC (70-80 cm). CONCLUSION: The study showed that Asian Indians have excess cardiovascular risk at BMI and WC values considered "normal." These data suggested that definitions of "normal" ranges of BMI and WC need to be revised for Asian Indians.     

河南省7～18岁学生血压现状及影响因素分析

目的 分析河南省中小学生血压偏高现状,探讨其影响因素,为血压偏高的防控提供参考。方法 以参加2019年全国学生体质健康调研的河南省7～18岁学生共39 675人为研究对象,于2019年9—10月收集其血压、身体发育相关指标,描述并比较男女、城乡各年龄组血压偏高检出率,利用多因素logistic回归分析血压偏高的影响因素。结果 血压偏高总检出率男生为20.8%,大于女生的12.4%(χ²=504.706,P<0.001),城市学生为16.2%,略小于乡村学生的17.0%(χ²=5.294,P=0.022);超重肥胖学生血压偏高检出率为25.4%,大于体重正常或消瘦学生的13.7%(χ²=734.088,P<0.001),所有学段均为超重肥胖学生检出率大于体重正常或消瘦学生;血压与腰围、体重、BMI均呈现正相关,收缩压与三者的相关系数分别为0.326、0.555、0.461,舒张压与三者的相关系数分别为0.230、0.390、0.326,P均<0.001;多因素logistic回归结果显示,与7～9岁年龄组...     

中国东部地区青少年肥胖类型及其与血压的关系

目的探讨2016-2017年我国东部地区12个省(直辖市)12~17岁青少年肥胖类型和血压关系。方法采用多阶段分层随机抽样,选取"2016-2017年中国儿童与乳母营养健康监测"项目中我国东部地区12~17周岁的青少年共8279人作为研究对象。依据体质指数、腰高比将研究对象划分为非肥胖、一般性肥胖、中心型肥胖、复合型肥胖4种类型。依据"中国3~17岁儿童每岁、身高对应的血压标准"判定不同肥胖类型人群的正常高值血压、血压偏高的情况。利用χ²检验、方差分析与多水平线性模型、多水平Logistic回归模型分析不同肥胖类型与血压的关系。结果中国东部地区12~17岁青少年正常高值血压检出率为13.66%(1069人),血压偏高检出率为18.79%(1782人)。其中非肥胖组正常高值血压检出率12.85%(732人),血压偏高检出率13.79%(999人);一般性肥胖组正常高值血压检出率20.45%(99人),血压偏高检出率23.62%(160人);中心型肥胖组正常高值血压检出率6.95%(32人),血压偏高检出率14.64%(87人);复合型肥胖组正常高值血压检出率16.68%(206人),血压偏高检出率42.42%(536人)。血压偏高检出率男女生间(χ²=8.05,P<0.01)差异有统计学意义;多水平模型结果:中心性肥胖仅女生血压偏高风险显著高于非肥胖组(OR=1.50,95%CI 1.12~2.02);肥胖的男、女生正常高值血压(OR=2.05,95%CI 1.62~2.58;OR=1.83,95%CI 1.38~2.42)、血压偏高(OR=2.06,95%CI 1.59~2.67;OR=1.57,95%CI 1.15~2.14)的风险均显著高于非肥胖组,;复合型肥胖的男、女生正常高值血压(OR=3.80,95%CI 3.19~4.51;OR=2.79,95%CI 2.30~3.37)、血压偏高(OR=4.07,95%CI 3.39~4.88;OR=2.84,95%CI 2.32~3.46)的风险显著高于非肥胖组。结论中国东部地区12~17岁青少年群体中,不同肥胖类型与血压水平相关程度不同,复合型肥胖血压偏高风险最高。     

Relationship of BMI, waist circumference, and weight change with use of health services by older adults

OBJECTIVE: To examine the relationship of BMI, waist circumference (WC), and weight change with use of health care services by older adults. RESEARCH METHODS AND PROCEDURES: This was a prospective cohort study conducted from 2001 to 2003 among 2919 persons representative of the non-institutionalized Spanish population > or =60 years of age. Analyses were performed using logistic regression, with adjustment for age, educational level, size of place of residence, tobacco use, alcohol consumption, and presence of chronic disease. RESULTS: Obesity (BMI > or = 30 kg/m(2)) and abdominal obesity (WC >102 cm in men and >88 cm in women) in 2001 were associated with greater use of certain health care services among men and women in the period 2001-2003. Compared with women with WC < or = 88 cm, women with abdominal obesity were more likely to visit primary care physicians [odds ratio (OR): 1.36; 95% confidence limit (CL): 1.06-1.73] and receive influenza vaccination (OR: 1.30; 95% CL: 1.03-1.63). Weight gain was not associated with greater health service use by either sex, regardless of baseline BMI. Weight loss was associated with greater health service use by obese and non-obese subjects of both sexes. In comparison with those who reported no important weight change, non-obese women who lost weight were more likely to visit hospital specialists (OR: 1.45; 95% CL: 1.02-2.06), receive home medical visits (OR: 1.61; 95% CL: 1.06-2.45), be hospitalized (OR: 1.88; 95% CL: 1.29-2.74), and have more than one hospital admission (OR: 2.31; 95% CL: 1.19-4.47). DISCUSSION: Obesity and weight loss are associated with greater health service use among the elderly.     

延边地区不同指标肥胖高中生高血压分布特点

目的分析吉林省延边地区不同指标肥胖汉族青少年高血压患病特点。方法于2008-2009年在延边地区安图县采用整群抽样方法抽取4所学校高三汉族学生1 785人,于清晨空腹安静状态下测量全部学生身高、体重、腰围(WC)及血压,分别以体质指数(BMI)和腰围作为评价肥胖的指标。结果在BMI正常、超重和肥胖男生高血压患病率分别为18.5%、39.1%和56.0%,女生分别为6.7%、14.3%和33.3%,不同体重男女生患病率差异有统计学意义(χ男2=37.8,χ女2=17.9,均P<0.00);在腰围正常和异常男生中高血压患病率分别为20.8%和32.2%,差异有统计学意义(χ2=5.9,P<0.01);多因素分析结果表明,超重和肥胖学生高血压患病危险性明显升高,其OR值分别为6.008和2.668;BMI和WC均异常组、单纯BMI异常组及单纯WC异常组的高血压患病危险性(OR值)依次为3.586、2.777和0.500。结论青少年BMI对血压升高的影响可能大于WC,且具有计量反应关系;BMI合并WC明显升高高血压患病危险性。     

西昌市社区居民中心性肥胖流行特征与影响因素分析

目的 了解四川省西昌市居民的中心性肥胖流行现况与影响因素,为后续当地相关的干预措施的制定提供理论依据与数据支持。方法 综合考虑经济水平、民族构成、地理位置等因素,在西昌市选择6个调查点,根据调查点社区人口数确定抽样比例,采用简单随机抽样的方法抽取18周岁及以上的成年居民进行问卷调查与体格检查,对所得数据进行描述性分析、单因素χ2分析与多因素logistic回归分析。结果 共纳入874名居民,中心性肥胖率为39.24%。单因素分析结果显示,不同饮酒情况（χ2=4.914,P<0.05）、高血压患病情况（χ2=15.869,P<0.001）、BMI（χ2=300.521,P<0.001）的成年居民中心性肥胖率不同。多因素分析结果显示,饮酒者（OR=1.545,95%CI:1.028～2.322）、高血压患者（OR=1.684,95%CI:1.093~2.592）发生中心性肥胖的风险所增加;相较于正常体重（18.5kg/m²≤BMI<23.9kg/m²）的居民,BMI<18.5kg/m²组别人群（OR=0.114,95%CI:0.015~0.843）发生中心性肥胖的风险更低,而BMI≥24.0kg/m²组别人群（OR=12.196,95%CI:8.630~17.234）则风险更高。 结论 西昌市成年居民中心性肥胖率较低。BMI<18.5kg/m²为中心性肥胖的保护因素,而饮酒、高血压患病、BMI≥24.0kg/m²为中心性肥胖的危险因素。     

全髋关节置换术前的肥胖状态对术后远期翻修率的影响

目的探讨全髋关节置换术(total hip arthroplasty,THA)前的肥胖状态对术后远期翻修率的影响。方法回顾性分析2004年1月~2005年12月在北京市平谷区医院行THA的患者418例,其中男性262例,女性156例,以术前体质量指数(body mass index,BMI)将患者分为肥胖组(BMI≥30 kg/m2)和非肥胖组(BMI30 kg/m2),比较两组患者THA术后远期翻修情况的差异。结果肥胖组和非肥胖组患者THA术后5年人工关节翻修率分别为5.4%和3.1%,两组间差异无统计学意义(P0.05);肥胖组和非肥胖组患者THA术后10年人工关节翻修率分别为15.5%和8.0%,两组间差异有统计学意义(P0.05)。THA术后10年,肥胖组患者的翻修风险是非肥胖组患者的2.12倍(OR=2.12,95%CI为1.13~3.98);肥胖组患者因髋臼和(或)股骨假体松动而行翻修手术的风险是非肥胖组患者的2.63倍(OR=2.63,95%CI为1.03~6.77)。结论 THA术前肥胖会增加术后远期翻修率。