耳鸣认知压力对耳鸣严重程度的影响

目的 分析耳鸣患者对耳鸣的不正确认识与耳鸣对生活质量影响之间的相关性.方法 选择以耳鸣为第一主诉的192例患者为研究对象,年龄18~83岁,平均45±15.52岁;男99例,女93例,按年龄分为青年组(≤44岁)111例,中年组(45~59岁)42例,老年组(≥60岁)39例;男性患者耳鸣平均时间25.67±37.71月(0.20~216.00月),女性患者耳鸣平均时间27.12±45.42月(0.10~300.00月).所有对象均填写普通话版耳鸣问卷量表(Mandarin tinnitus questionnaire,MTQ)和普通话版耳鸣残疾评估量表(Chinese Mandarin tinnitus handicap inventory,THI-CM),分析MTQ中认知压力(cognitive distress,CD)与耳鸣严重程度之间的相关性.结果 192例患者MTQ平均得分为36.95±20.06分(6.00~88.00分),其中认知压力(问题17、18、23、41、42)平均得分为2.36±2.55分,问题17、18、23、41、42平均分分别为:2.81、2.63、2.59、2.40、2.41.THI-CM平均分为23.89±20.06分(2.00~90.00分),CD和THI-CM的相关系数为0.64(P<0.01),男性和女性CD和THI-CM的相关系数分别为0.63和0.66(P<0.01);青年组、中年组和老年组CD和THI-CM的相关系数分别为0.02、0.07、0.38(P>0.01).THI-CM评分为无残疾、轻度、中度和重度残疾组的CD和THI-CM的相关系数分别为0.30(P<0.01)、0.29(P>0.01)、-0.12(P>0.01)、0.23(P>0.01).结论 本组对象认知压力与耳鸣残疾严重程度之间有一定相关性,认知压力得分随着耳鸣严重程度的增加而增加;男性和女性均表现出相关性,但相关性不强;年龄和认知压力之间无相关性,但随着年龄增长,两者之间的相关系数增大,表明耳鸣患者的生活质量可能随着年龄增加,越容易受到对耳鸣不正确认知的影响.     

耳鸣严重程度与焦虑的相关性研究

目的:研究耳鸣严重程度与焦虑的相关性,探讨其在耳鸣康复中的作用。方法:对以耳鸣为第一主诉就诊的119例患者,用耳鸣一般情况问卷表、耳鸣残疾量表(THI)和焦虑自评量表(SAS)进行横断面调查,分析其相关性。结果:THI得分和SAS得分正相关(r=0.573,P<0.01),THI得分分级和SAS得分正相关(r=0.551,P<0.01)。耳鸣严重程度越高,焦虑得分越高。结论:耳鸣严重程度与焦虑呈中度正相关性,对以耳鸣为第一主诉且其THI得分分级≥中度(即≥38分)的耳鸣患者,应注意了解其焦虑程度,进行必要的心理干预,有助于耳鸣患者的康复。     

性别、年龄、听力损失程度与耳鸣严重程度的关系探讨

目的用耳鸣残疾量化表得分评估耳鸣患者耳鸣的严重程度,分析患者的性别、年龄、听力损失程度是否影响耳鸣严重度。方法对97例以耳鸣为第一主诉的主观性耳鸣患者进行系统的耳鼻咽喉科检查、听力学检查和耳鸣残疾评估量表(tinnitus handicap inventory,THI)评分,分析患者的性别、年龄及听力损失程度与THI得分的关系。结果 97例中,男36例,年龄18～78岁(平均47±12.5岁);女61例,年龄15～71岁(平均55±17.6岁),经Wilcoxon秩和检验分析,不同性别间患者的THI得分差异无统计学意义(P>0.05),Spearman相关性分析显示,耳鸣患者的年龄、听力损失程度与THI得分之间无明显的相关性(均为P>0.05)。结论耳鸣残疾评估量表得分分析可知耳鸣患者的性别、年龄、听力损失程度对耳鸣严重程度无明显的影响。     

耳鸣残疾量表在耳鸣应用中的现状和分析

耳鸣残疾量表（tinnitus handicap inventory,THI）及其翻译量表是临床诊断耳鸣常用而有效的工具,目前被广泛应用于耳鸣的评估。本文将THI及其翻译量表在耳鸣中的应用进行综述和分析,以便为临床医师和研究者提供有效、实用的参考。     

持续性特发性耳鸣严重程度的相关因素分析

目的 探讨导致持续性特发性耳鸣严重程度的相关因素.方法 分析870例持续性特发性主观性耳鸣患者的一般资料、病史、听力学结果、耳鸣匹配实验、耳鸣残疾量表、匹兹堡睡眠质量指数量表和焦虑自评量表,应用多因素Logistic回归分析研究与患者耳鸣严重程度相关的因素.结果 ①性别(P＜0.001)、年龄(P=0.010)、耳鸣主...     

慢性耳鸣严重程度影响因素分析

目的 通过对慢性原发性耳鸣的病史采集、听力学检测、耳鸣心理声学检测、伴发疾病症状采集,探讨哪些因素与慢性耳鸣患者耳鸣严重程度相关。方法 2016年4月-2019年12月以耳鸣为第一主诉就诊于秦皇岛市第一医院耳科门诊的病程大于6个月的慢性耳鸣患者,通过填写耳鸣残疾量表（THI）、耳鸣病史采集（性别、年龄、耳鸣病程、侧别、在何种环境下能感知耳鸣）、听力学检测（纯音听阈测定、LDL测试）、耳鸣心理声学检测、可能与耳鸣相关的全身疾病症状（头痛、打鼾、失眠、血管危险因素）,应用多因素有序logistic回归进行分析。结果 性别、年龄、病程、耳鸣与环境、PTA、耳鸣侧别、匹配频率、匹配响度、残余试验、头痛、血管危险因素、打鼾与慢性耳鸣严重程度之间无相关性。Feldmann曲线类型、听觉过敏、睡眠障碍与慢性耳鸣严重程度之间有相关性。结论 严重的慢性主观性耳鸣治疗过程中应关注听觉过敏和睡眠障碍的治疗。     

TSG助听器用于耳鸣患者的临床结果

目的 评估TSG助听器(GN Resound Live 9 TS)改善患者耳鸣的效果,从而检验该技术用于治疗单纯性耳鸣和耳鸣伴有听力障碍患者的可行性和疗效.方法 采用耳鸣残疾评估量表(TinnitusHandicap Inventory,THI)作为评估素材,分别对9名受试者在TSG助听器配戴前后的耳鸣残疾程度进行评估.结果 ①全部受试者配戴GN Resound Live 9 TS助听器前后THI总分和各条目得分均有显著性差异(P<0.0001) ; ②GN Resound Live 9 TS助听器配戴前后受试者THI的功能性、情感性及严重性得分均得到显著性改善(P<0.0001).结论 GN Resound Live 9 TS助听器对单纯耳鸣受试者或耳鸣伴有轻中度感音神经性听力损失者均显示出明显的改善作用.     

慢性耳鸣的临床特点及严重程度影响因素分析

目的 分析慢性耳鸣的临床特点及严重程度的影响因素。方法 回顾性分析1 452例慢性耳鸣患者的临床资料,所有患者均进行详细的病史询问、纯音测听和耳鸣心理声学评估,填写耳鸣障碍量表(tinnitus handicap inventory, THI)、焦虑自评量表(self-rating anxiety scale, SAS)或广泛性焦虑障碍量表(generalized anxiety disorder-7,GAD-7),抑郁自评量表(self-rating depression scale, SDS)或抑郁筛查量表(patient health questionnaire-9,PHQ-9)、匹兹堡睡眠质量指数量表(pittsburgh sleep quality index, PSQI)和听觉过敏问卷等。分析耳鸣患者的临床特点,并以THI评分≥38分为中-重度耳鸣组,THI评分≤36分为轻度耳鸣组,以THI分组为应变量,上述各因素为自变量,采用Logistic回归分析探究各因素与耳鸣严重程度的相关性。结果 1 452例慢性耳鸣患者中,轻度耳鸣625例(43.04%),中-重度耳鸣827例(...     

全参数生物反馈指标在主观性耳鸣患者中的应用

目的研究全参数生物反馈在治疗主观性耳鸣患者中的效果。方法对20例主观性耳鸣患者行全参数生物反馈治疗10次,观察治疗前后耳鸣残疾评估量表（Tinnitus Handicap Inventory,THI）得分及全参数生物反馈指标的变化。结果耳鸣患者治疗前后THI总分分别为44．9±22．3和28．0±14．8,差异达到极显著性水平（P〈0．01）;冶疗前后生物反馈指标肌电分别为6．7±1．6和5．1±1．2,差异达到显著性水平（P〈0．05）、治疗前后仪波分别为13．3±6．4和16．4±6．2,差异极显著（P〈0．01）、治疗前后SMR波分别为5．4±1．6和6．2±2．2,差异显著（P〈0．05）。结论主观性耳鸣患者进行生物反馈治疗有效,可明显降低THI总分,改善耳鸣症状,随着耳鸣患者症状减轻,其对应生物反馈指标也发生相应改变。     

Interaction of tinnitus suppression and hearing ability after cochlear implantation

Objectives: To study the postoperative impact of cochlear implants (CIs) on tinnitus, as well as the impact of tinnitus on speech recognition with CI switched on.

Methods: Fifty-two postlingual deafened CI recipients (21 males and 31 females) were assessed using an established Tinnitus Characteristics Questionnaire and Tinnitus Handicap Inventory (THI) before and after cochlear implantation. The tinnitus loudness was investigated when CI was switched on and off in CI recipients with persistent tinnitus. The relation between tinnitus loudness and recipients’ satisfaction of cochlear implantation was analyzed by the visual analogue scale (VAS) score.

Results: With CI ‘OFF’, 42?CI recipients experienced tinnitus postimplant ipsilaterally and 44 contralaterally. Tinnitus was totally suppressed ipsilateral to the CI with CI ‘ON’ in 42.9%, partially suppressed in 42.9%, unchanged in 11.9% and aggravated in 2.4%. Tinnitus was totally suppressed contralaterally with CI ‘ON’ in 31.8% of CI recipients, partially suppressed in 47.7%, unchanged in 20.5%. Pearson correlation analysis showed that tinnitus loudness and the results of cochlear implant patients satisfaction was negatively correlated (r?=?.674, p?Conclusion: The study suggests six-month CI activation can be effective for suppressing tinnitus. The tinnitus loudness may affect patients’ satisfaction with the use of CI.     

Evaluation of tinnitus retraining therapy for patients with normal audiograms versus patients with hearing loss

Objective

A few chronic tinnitus patients show normal hearing thresholds in the pure tone audiometry from 125 Hz to 8000 Hz (≤20 dB). We report the characteristics of the course of those patients underwent tinnitus retraining therapy (TRT) compared with other patients suffering from chronic and severe tinnitus.

神经调节与耳鸣

耳鸣被定义为没有任何外部声音源的声音感知，其中慢性耳鸣常对生活质量产生影响。到目前为止，还没有关于耳鸣的因果治疗的记录，大多数药理学和身心治疗方式旨在减少耳鸣对生活质量的影响，提高患者的适应性。随着对耳鸣发生和维持的病理生理机制的深入研究，各种不同的神经调节干预措施也被开发、设计出来，并显示出有希望的结果。这篇综述的目的是从大量的最新文献中，对耳鸣研究中的不同神经调节方法进行简要的概述。     

A questionnaire study of the quality of life and quality of family life of individuals complaining of tinnitus pre- and postattendance at a tinnitus clinic

Tinnitus is a condition that is difficult to treat, and treatment outcomes are difficult to measure. The majority of people who experience tinnitus are not troubled by it; however, the troubled minority are referred by an otorhinolaryngologist for specialist clinic help. The aim of this study was to investigate how the impact of tinnitus changes following attendance at a tinnitus clinic and to find out how acceptable the questionnaires used were for measuring recovery. Fifty-seven tinnitus sufferers completed three questionnaires covering the characteristics of tinnitus, and its effect on daily life, quality of life, and quality of family life, before and after treatment at the Nottingham Tinnitus Clinic. Questionnaires were answered at patients' homes while they were on the waiting list to attend the clinic, and again 1 year after their first attendance. Measures of functional and social handicap were significantly reduced following attendance at the clinic (mean change in functional handicap=13%, p<0.01, and mean change in social handicap=8%, p<0.01). Quality of life was significantly better after treatment at the clinic (mean visual analog scale difference=6.5%, p=0.01). We conclude that attendance at the Nottingham Tinnitus Clinic had a positive effect on the impact of tinnitus on patients and their families, and that the questionnaires gave an accurate measure of patient distress.     

A Hebrew adaptation of the tinnitus handicap inventory

Abstract

Objective: To establish a Hebrew version of the English THI. Design: The English THI (THI-E) was translated into Hebrew by two bilingual investigators, independently. A third investigator then constructed the final Hebrew THI version (THI-H) from the two translations. This version was administered to fifty consecutive patients at the tinnitus clinic. Participants also assessed tinnitus severity and loudness, and completed the Hebrew versions of the Beck's depression inventory and the state anxiety inventory. Study sample: The participants were fifty consecutive patients (older than 18 years of age, with a tinnitus lasting over three months) who were referred to a tinnitus clinic (none of them declared compensation seeking). Results: A very good internal consistency was found (α = 0.93), with significant correlation between the subscales of the THI-H and the Beck depression inventory score and the state anxiety inventory score. Conclusions: A valid and reliable THI-H questionnaire was constructed.

Sumario

Objetivo: Establecer una versión en Hebreo del THI en Inglés. Diseño: El THI en Inglés (THI-E) fue traducido al Hebreo por dos investigadores bilingües de manera independiente. Un tercer investigador elaboró después la versión final del THI en Hebreo (THI-H) a partir de las dos traducciones. Esta versión se administró a cincuenta pacientes consecutivos en la clínica de acufeno. Los participantes también evaluaron la severidad del acufeno y su intensidad subjetiva y completaron las versiones en Hebreo del Inventario de Depresión de Beck y el Inventario del Estado de Ansiedad. Muestra de Estudio: Los participantes fueron cincuenta pacientes consecutivos (mayores de 18 años con acufeno de duración mayor a 3 meses) que fueron referidos a la clínica de acufeno (ninguno de ellos declaró búsqueda de compensación). Resultados: Se encontró una muy buena consistencia interna (α = 0.93), con correlación significativa entre las subescalas del THI-H y las puntuaciones del Inventario de Depresión de Beck y del Inventario de Estado de Ansiedad. Conclusiones: Se elaboró un Cuestionario de THI-H válido y confiable.     

临床耳鸣治疗中咨询问题和模式的建立

耳鸣是一种极为常见的症状,其病因和影响因素复杂多样,人群中耳鸣的患病率高达10-15%,而其中80%的人可不需要进行临床上的治疗或干预,但患者对耳鸣的容忍性却与患者的心理状态和社会方面的因素密切相关。有效的咨询又可使很多患者的耳鸣症状得到缓解,因此,系统全面的耳鸣咨询被认为是耳鸣治疗和康复中极其重要且不可缺少的组成部分,当然,咨询的方式在临床医生之间由于医生的治疗方案的选择和理念等不同而差异很大。为此,本文从耳鸣咨询的目的和作用、内容、方法和手段以及注意事项等方面进行阐述,最后就建立临床耳鸣咨询的模式提出一套方案。     

两种激素鼓室内灌注治疗主观性耳鸣的近期临床观察

目的:探讨鼓室内灌注醋酸泼尼松龙和地塞米松治疗主观性耳鸣的疗效。方法:选择病史在1个月以上已接受过口服药物治疗的主观性耳鸣患者73例(78耳),醋酸泼尼松龙组鼓室灌注醋酸泼尼松龙注射液,地塞米松组鼓室灌注地塞米松注射液,对照组口服卡马西平。3组均同时口服甲磺酸倍他司汀片、维生素B1片和甲钴胺片。所有患者在治疗前、治疗结束时再次行纯音测听和耳鸣匹配测试,随访6个月。结果:73例患者(78耳)均完成全部的治疗及随访。治疗结束时,醋酸泼尼松龙组、地塞米松组、对照组耳鸣治疗有效率分别为48.6%、33.3%、44.0%;6个月后3组的耳鸣控制率分别是45.7%、27.8%、36.0%。结论:鼓室内应用激素能改善主观性耳鸣,对口服药物无效的患者可以选用鼓室灌注类固醇激素。     

Electric field navigated transcranial magnetic stimulation for chronic tinnitus: A pilot study

Objective: Repetitive transcranial magnetic stimulation (rTMS) has shown potential in reducing tinnitus symptoms. We evaluated effects of electric field (E-field) navigated rTMS targeted neuroanatomically according to tinnitus pitch. Design: In this open methodological pilot study, the patients received E-field navigated 1-Hz rTMS in daily treatment sessions to the left superior temporal gyrus, targeted according to tonotopic representation of their individual tinnitus pitch. Patients rated their tinnitus intensity and annoyance with a numeric rating scale (NRS) from 0 to 10 at the baseline and after each rTMS session. They also rated their global impression of change (scale ? 3 to + 3) after the treatment. Study sample: Thirteen patients (mean age 53 years; 10 men, 3 women) with chronic, intractable tinnitus. Results: The mean intensity was 7.1 (SD 1.8) at the baseline, decreasing to 4.5 (SD 2.2) after the rTMS (p < 0.0001). The mean annoyance 7.0 (SD 1.8) at the baseline decreased to 4.0 (SD 2.4) after the treatment (p < 0.0001). Intensity diminished at least 30% in 8/13 patients and annoyance in 9/13 patients. A total of 10/13 patients felt subjective benefit from the treatment. Conclusions: These preliminary observations suggest that E-field-rTMS may improve the current treatment options for intractable tinnitus.     

Neurofeedback for subjective tinnitus patients

Objective

Previous studies report that enhanced power in the delta range (1.5–4 Hz) and reduced power in the alpha frequency band (8–12 Hz) were most pronounced in the temporal regions. These studies referred to the 8–12 Hz activity as tau activity, and they created a new neurofeedback protocol to treat tinnitus using a temporally generated tau rhythm (8–12 Hz) and slow waves in the delta range (3–4 Hz) for feedback. This study aims to repeat this protocol and to evaluate its effect on tinnitus.

Methods

Fifteen normal-hearing patients with tinnitus were treated with the neurofeedback protocol. The Tinnitus Handicap Inventory and Visual Analogue Scales were administered before and after treatment and at 1, 3 and 6 months post-treatment.

Results

After therapy, all questionnaires scores were significant improved, and the improvements persisted throughout the followup period. Moreover, an increasing trend in the tau/delta ratio was observed; specifically, the trend was more stable respect of the pre-recording measure. However, only in some subjects may the signal alone be enough to develop the correct behaviors.

Conclusion

Further studies are necessary to characterize the tinnitus subjects who recovered from and adapted to this psychophysical condition and, therefore, responded to neurofeedback therapy.