全髋与半髋关节置换术治疗老年股骨颈骨折的临床效果

目的 分析全髋与半髋关节置换术治疗老年股骨颈骨折的临床疗效.方法 100例老年股骨颈骨折患者,采用随机数字表法分为观察组和对照组,每组50例.对照组行半髋关节置换术治疗,观察组行全髋关节置换术治疗.比较两组患者临床疗效,手术时间、手术出血量、总引流量和完全负重时间,术后髋关节评分表(Harris)评分、假体髋臼外展角度...     

不同置换术治疗老年股骨颈骨折的临床疗效对比

目的比较不同置换术治疗老年股骨颈骨折临床疗效的差异。方法选取我院收治的97例老年股骨颈骨折患者,随机分为对照组48例和观察组49例,对照组患者使用半髋关节置换术治疗,观察组患者使用全髋关节置换术治疗。比较两组手术时间、术中出血量、术后髋关节功能恢复时间、Harris评分和并发症发生率的差异。结果观察组手术时间、术中出血量和术后髋关节功能恢复时间均多于对照组,两组比较差异有统计学意义(P<0.05);Harris评分显示观察组优良率为93.9%(46/49),显著高于对照组的75.0%(36/48)(P<0.05);观察组术后并发症发生率显著低于对照组(P<0.05)。结论全髋关节置换术与半髋关节置换术比较,临床疗效较好且并发症发生率低,在患者能耐受的情况下,可作为老年股骨颈骨折治疗首选方法。     

全髋与半髋关节置换术治疗老年股骨颈骨折的临床疗效差异研究

目的探讨全髋与半髋关节置换术治疗老年股骨颈骨折的临床疗效差异。方法选取2016年10月至2017年10月我院收治的股骨颈骨折老年患者96例,随机分为对照组和观察组,各48例。对照组采用半髋关节置换术治疗,观察组实施全髋关节置换术治疗。对比两组手术情况、术后恢复情况以及并发症发生情况。结果观察组术中出血量、手术时间均显著高于对照组,但观察组术后并发症发生率小显著低于对照组切术后12个月Harris评分明显高于对照组(P <0.05),差异有统计学意义。结论采用全髋关节置换术治疗老年股骨颈骨折相比半髋关节置换术疗效更显著,术后膝关节功能恢复更为良好,并发症发病率较低,安全性更高,值得推广。     

人工髋关节置换术和股骨头置换术治疗老年股骨颈骨折的疗效分析

目的:比较人工髋关节置换术和股骨头置换术治疗老年股骨颈骨折患者的临床疗效。方法:回顾分析2005～2009年我院收治的109例老年股骨颈骨折患者,随机分为髋关节置换组和股骨头置换组,其中,髋关节置换组57例,股骨头置换组52例,比较这两组患者手术持续时间、住院时间、术中出血量、术后引流量、早期并发症及临床疗效。结果:两组患者围手术期手术持续时间、住院时间、术中出血量、术后引流量等情况相比较,差异无统计学意义(P>0.05);观察组Harris评分和优良率明显优于对照组,两组比较差异有统计学意义(P<0.05);且观察组并发症明显小于对照组,具有统计学差异(P<0.05)。结论:全髋关节置换术和人工股骨头置换术治疗老年股骨颈骨折相比较,前者疗效佳,并发症少,值得临床进一步推广应用。     

髋关节置换术与内固定术治疗老年股骨颈骨折48例临床分析

目的探讨髋关节置换术与内固定术治疗老年股骨颈骨折的临床疗效,为临床选择合适的治疗方法提供依据。方法将96例老年股骨颈骨折患者按照随机、自愿原则分为对照组和观察组,各48例。对照组患者采用切开复位内固定术治疗,观察组患者给予髋关节置换术治疗。术后进行随访,比较两组患者手术时间、术中出血量、卧床时间、术后并发症及Harris关节评分。结果观察组手术时间及术中出血量明显高于对照组,但术后卧床时间(15.9±2.8)d和并发症发生率16.7%明显小于对照组患者,差异均有统计学意义(P<0.05)。观察组患者Harris关节评分优良率93.8%明显高于对照组64.6%,差异有统计学意义(P<0.05)。结论髋关节置换术治疗老年股骨颈骨折患者临床疗效可靠,值得在临床中推广应用。     

全髋关节置换术治疗老年股骨颈骨折42例临床疗效分析

目的探讨全髋关节置换术治疗老年股骨颈骨折的临床疗效。方法选择79例股骨颈骨折的老年患者,按随机方法分成两组。观察组42例采用全髋关节置换术治疗,对照组37例采用半髋关节置换术治疗,比较两组患者手术时间、手术中出血量、术后并发症发生率及髋关节功能恢复时间。随访1年,根据Harris评分标准对髋关节功能进行评分比较愈后。结果虽然观察组患者手术时间及手术中出血量明显多于对照组(P<0.05),但观察组患者术后有效率、并发症发生率及髋关节功能恢复情况明显优于对照组(P<0.05)。结论全髋关节置换术能减少手术并发症,明显改善髋关节功能,提高老年患者的生活质量,但全髋关节置换术术中损伤较大,应根据患者的身体状态及骨折损伤程度选择合适的手术方式。     

全髋关节置换术与人工股骨头置换术治疗老年人股骨颈骨折的疗效对比

目的对比分析全髋关节置换术与人工股骨头置换术治疗老年股骨颈骨折的疗效,探究临床治疗老年股骨颈骨折的有效术式。方法将72例老年股骨颈骨折患者随机分为观察组（n=36）与对照组（n=36）,前者接受全髋关节置换术治疗,后者接受人工股骨头置换术治疗,现对比分析两组疗效。结果（1）观察组手术时间显著长于对照组,术中出血量、术后引流血量显著多于对照组,两组比较差异有统计学意义（P〈0．05）。（2）两组患者术后早期并发症发生率相比差异无统计学意义（P〉0．05）。（3）术后1年,两组患者Harris评分、优良率相比差异无统计学意义（P〉0．05）;术后3年,观察组患者Harris评分、优良率显著高于对照组,两组比较差异有统计学意义（P〈0．05）。结论人工股骨头置换术的手术创伤较小,但是全髋关节置换术的远期疗效要优于人工股骨头置换术。     

骨折内固定术与全髋关节置换术治疗老年股骨颈骨折的临床效果比较

目的:分析骨折内固定术与全髋关节置换术治疗老年股骨颈骨折的临床疗效。方法:选取2014年1月至2016年12月我院收治的84例老年股骨颈骨折患者,按照手术方式将其分为两组,各42例。研究组行骨折内固定术,对照组行全髋关节置换术,对比手术效果。结果:研究组治疗优良率低于对照组,并发症发生率高于对照组,但手术时间、术中失血量研究组优于对照组,差异有统计学意义(P0.05)。结论:全髋关节置换术治疗老年股骨颈骨折疗效更佳,安全性更高,可推广应用。     

不稳定型老年股骨颈骨折采用全髋与半髋关节置换治疗的效果对比

目的探讨全髋与半髋关节置换治疗不稳定型老年股骨颈骨折的临床效果。方法将我院近年来收治的90例不稳定形老年股骨颈骨折患者随机分为观察组与参考组,各为45例,观察组采用半髋关节置换治疗,参考组采用全髋关节置换治疗,对两组患者手术时间、失血量、住院时间进行观察,比较两组患者通过髋关节功能Harris评分对患者治疗效果。结果观察组患者手术时间短于参考组但比较无统计学意义(P>0.05);观察组术中失血量及术后住院时间均明显少与参考组(P<0.05);两组患者术后Harris评分比较无统计学意义(P>0.05)。结论全髋置换术与半髋关节置换手术时间比较无差异,然而半髋关节置换术对患者机体损伤较小,患者康复效果亦良好,推荐使用。     

骨折内固定术与全髋关节置换术治疗老年股骨颈骨折的临床效果比较

目的:分析骨折内固定术与全髋关节置换术治疗老年股骨颈骨折的临床疗效。方法:选取2014年1月至2016年12月我院收治的84例老年股骨颈骨折患者,按照手术方式将其分为两组,各42例。研究组行骨折内固定术,对照组行全髋关节置换术,对比手术效果。结果:研究组治疗优良率低于对照组,并发症发生率高于对照组,但手术时间、术中失血量研究组优于对照组,差异有统计学意义(P0.05)。结论:全髋关节置换术治疗老年股骨颈骨折疗效更佳,安全性更高,可推广应用。     

Role of the liver in the disposition of intravenous nitroglycerin in the rat

Previous studies have indicated that the liver is the main site of nitroglycerin (NTG) elimination when the drug is systematically infused. To examine this hypothesis, we measured the apparent systemic clearance (Cls) of nitroglycerin in anesthesized rats receiving a constant intravenous infusion at a dose of 100 micrograms per kg per min. Animals were divided into shunt and sham groups; the former had undergone a portal vein ligation 10 days prior to the study, while the latter was subjected to a sham operation. On the study day, half of the animals of each group also received probenecid at 200 mg/kg, i.v., a drug previously reported to inhibit organic nitrate ester reductase (ONER) activity in rat liver. Arterial NTG samples were obtained at 41, 43 and 45 min of infusion in all four experimental groups; Cls was 439 +/- 32 ml per kg per min (mean +/- S.E.) in sham, 460 +/- 44 in sham and probenecid, 477 +/- 39 in shunt, and 461 +/- 34 in shunt and probenecid animals. During NTG infusion, hepatic blood flow (measured with a constant infusion of indocyanine green) was decreased markedly in shunted rats as was liver/body weight, indicating hepatic atrophy. The specific activity of hepatic ONER was similar in all four groups. In spite of marked differences in hepatic blood flow and hepatic mass, the Cls was similar in all four groups. The liver does not appear to be a major site for the elimination of systemic nitroglycerin as hitherto assumed.     

半导体激光治疗老年人压疮疗效观察

目的探讨半导体激光局部照射治疗老年人压疮疗效.方法:收集2012年1月-2015年6月48例压疮患者,分为半导体组和常规组各24例.常规组采用常规治疗,半导体组采用半导体激光加常规治疗,10 d为1个疗程,不超过3个疗程.疗程结束后比较两组疗效.结果:半导体组压疮愈显率为83.33％,创面愈合时间为(12.75±5.51)d,常规组分别为54.17％和(19.63±8.65)d,组间差异有统计学意义(P＜0.05),两组均未见不良反应.结论:半导体激光加常规治疗压疮效果肯定,无明显不良反应,且操作简便.     

Nifedipine in the treatment of hypertension in the elderly

The effect of nifedipine monotherapy, retard tablets, 20 mg bid, was evaluated in 23 hypertensive patients, mean age, 79 +/- 2 years. Twenty-one patients completed an eight-week study. Blood pressure (BP) decreased to 160/90 mm Hg in 15 patients; in four additional patients diastolic BP dropped by 15% to 28%. In a subset of five patients with isolated systolic hypertension, a significant reduction in systolic BP was noted. Side effects were relatively mild and only two patients discontinued the study. The results suggest that nifedipine monotherapy offers an alternative, logic, therapeutic approach to hypertension in the elderly.     

HACCP在学校集体食堂卫生管理中的应用研究

目的 通过HACCP在学校集体食堂管理中的应用,提高食品卫生水平,保障学生的身体健康。方法 HACCP原则。结果 食品卫生达到较高水平,极大地减少了食物中毒的发生。结论 提示HACCP原则可在学校集体食堂的卫生管理中发挥有效作用。     

The role of the gut flora in the reduction of sulphinpyrazone in the rat

Sulphinpyrazone underwent both reduction to a sulphide and oxidation to a sulphone after parenteral administration to normal Wistar rats. Oral administration was associated with a bioavailability of about 75% and with a 3-fold greater formation of the sulphide. However, no sulphide was detected in the plasma after oral administration of sulphinpyrazone to germ-free (BD/X) rats or normal rats treated with oral antibiotics. In vitro studies showed that the major site of reduction of sulphinpyrazone was the contents of the hind gut with little activity detected in the liver or other tissues. The sulphide was oxidised in vivo to sulphinpyrazone and small amounts of sulphone, while the latter underwent only slight reduction to sulphinpyrazone, but did not give detectable levels of the sulphide. These data suggest that the gut microflora are the main site of reduction of sulphinpyrazone in the rat in vivo.     

Problems in the evaluation of hypnosis in the treatment of alcoholism

Although hypnotherapy has been applied to alcoholism for over a century and is accepted by the AMA as a medically valid technique, the effectiveness of hypnosis in treating alcoholics remains controversial. Systematic evaluation has been hampered by the unique role of hypnosis as a cultural artifact, by problems in defining and verifying hypnotic intervention, by individual and situational variation in hypnotizability, and by difficulty in separating hypnosis from the therapies to which it is applied. Clinicians using hypnosis are likely to continue to base their claims for its effectiveness on intuition, especially since no study has demonstrated that hypnotherapy is contraindicated for patients requesting its use.