自体脂肪颗粒注射填充矫正哺乳后乳房不对称

目的：讨论自体脂肪颗粒注射填充隆乳矫正哺乳后乳房不对称。方法：采用注射器吸脂,生理盐水中自然漂洗脂肪颗粒,注射隆乳。结果：75例术后均无血肿、感染、坏死、色素沉着、感觉迟钝及脂肪栓塞等并发症,两侧乳房不对称得到满意矫正,移植的自体脂肪存活率65％～75％,外观满意,手感良好,无供区畸形,随访1～5年,受术者满意。结论：自体脂肪颗粒注射填充隆乳术是良好的矫正两侧乳房不对称的方法。     

湿性脂肪干细胞辅助自体颗粒脂肪移植术临床观察

目的:探讨湿性脂肪干细胞辅助自体颗粒脂肪注射移植术的有效性,旨在探索一种更方便、更安全、更高效干细胞辅助颗粒脂肪注射填充移植方法。方法:20ml一次性螺口注射器吸脂,自然静置悬浮后只排除注射器下层水分(若水份很少,亦可不排除),不漂洗和不排除静置后注射器内颗粒脂肪上层脂质(油脂)部分及颗粒脂肪微粒间液体部分,不离心分离浓缩纯化颗粒脂肪,直接注射移植;注射前受区先局部肿胀浸润麻醉使各层次组织蔬松分离,分层次注射移植,呈单点微量(0.5～1 ml)、多点、多平面、多隧道、无创钝针线状在形成隧道同时边退针边注射,将颗粒脂肪和干细胞"微粒"定位于受植床内,局部肌肉内可分多层注射以保证良好血运,尽量减少损伤和缩短操作时间。结果:术后随访1～3年,与笔者二年前在同等条件下所完成传统单纯颗粒脂肪湿性注射隆乳术和隆臀术及隆乳假体取出后即刻注射隆乳术等多量自体颗粒脂肪注射移植术后相比,临床效果均获明显提高。结论:湿性脂肪干细胞辅助自体颗粒脂肪注射移植技术,可一次手术完成,操作简易、快速、安全、经济、并发症少,宜临床推广普及应用,可做为现今多量自体颗粒脂肪注射填充移植美容和治疗方面首选技术。     

自体脂肪颗粒多层次注射填充重塑面部轮廓

目的:探讨自体脂肪颗粒多层次注射填充重塑面部轮廓的临床效果。方法:注射器吸脂,采用纱布分离和净化脂肪,直接取黄色脂肪颗粒转入1ml注射器,经多层次注射填充于面部。结果:对57例实施面部颗粒脂肪多层次注射填充患者,随访3~36个月,面部注射填充部位较前饱满、圆润,且无血肿、硬结、感染等并发症发生。临床取得了良好的重塑面部轮廓的效果。结论:自体脂肪颗粒注射填充重塑面部轮廓,效果持久稳定,是一种安全、理想的方法。     

自体脂肪颗粒面部注射移植30例临床分析

目的 探讨自体脂肪颗粒注射移植填充面部凹陷畸形的方法 和临床效果.方法 选择下腹部、大腿前外侧部、臀部作为脂肪供区,在静脉麻醉或局部浸润麻醉下行脂肪抽吸术,将抽吸的脂肪经生理盐水冲洗直至清亮,静置后将脂肪注射移植于颞部、面颊部、鼻唇沟等部位,注射量视局部情况而定.自2011年10月至2012年5月,共对30例求美者行自体脂肪颗粒面部注射移植取得了满意的效果.结果 本组共30例求美者,术后填充部位充盈,质地柔软,局部无硬结、感染、脂肪液化等并发症发生;术后随访3～6个月,外观自然,效果满意.结论 自体脂肪颗粒注射移植是矫治面部软组织凹陷及皱纹的有效方法,值得临床推广应用.     

自体脂肪颗粒移植在改善鼻唇沟凹陷中的应用

目的 探讨应用自体脂肪颗粒移植改善鼻唇沟凹陷的效果。方法 2011年11月至2014年12月,利用自体脂肪颗粒注射填充鼻唇沟凹陷91例。选取腰腹部或大腿作为脂肪供区,利用负压吸脂机获取脂肪颗粒,吸水浓缩法纯化后,多层次、多隧道、多点少量注射填充91例患者的鼻唇沟凹陷。结果 术后随访6~36个月,56例患者一次注射填充即达满意效果,35例患者经过两次注射填充达到满意效果。每侧注射量1.2~4.6 m L。本组患者均无严重并发症。结论自体脂肪颗粒移植注射填充鼻唇沟凹陷,效果优良,并发症少,值得临床推广应用。     

应用Body-jet水动力吸脂系统行自体脂肪颗粒隆乳术的体会

目的:探讨自体脂肪颗粒移植隆乳术较理想的方法及其临床效果。方法:应用Body-jet水动力吸脂系统抽吸腹部、臀部、大腿部的脂肪,同时纯化过滤脂肪,并将其均匀注射于乳房各层组织中。自2010年08月至2011年12月,我们应用Body-jet水动力吸脂系统为10例患者行自体脂肪抽吸的同时行注射隆乳术,每侧乳房一次注射剂量为100-270ml。结果:对10例患者首次手术后6个月进行复查,乳头水平围较首次手术即刻均有不同程度缩小。再次手术间隔6-12个月。术后乳房较丰满、圆润,形态自然,手感柔软。术后效果较满意。结论:自体脂肪颗粒是比较理想的软组织填充材料。应用Body-jet水动力吸脂系统行脂肪抽吸的同时利用抽吸的脂肪颗粒注射隆乳,可减少并发症的发生,提高手术效果,是目前较理想的自体脂肪颗粒移植隆乳的方法。     

自体脂肪颗粒移植在面部年轻化中的临床应用

目的:探讨自体脂肪颗粒移植在面部塑形和改善面部衰老的方法和临床效果。方法:以标准自体脂肪注射器负压吸引法吸取大腿、腹部脂肪颗粒,纯化后根据术前设计用脂肪抽吸针将脂肪颗粒注射至额颞部、面颊、苹果肌、泪沟、鼻唇沟、上睑、下颏等需要填充部位。结果:本组58例求美者无明显术后并发症。随访3~6个月,仅1例行2次注射。填充后面部较术前丰满,质感同周围组织,形态自然,面部衰老得以改善。结论:采用自体脂肪颗粒移植可达到丰满塑形、改善面部衰老的效果,符合面部软组织特征。     

自体脂肪颗粒移植在改善面部容貌中的应用

目的 探讨通过自体脂肪颗粒移植改善面部软组织容积缺损及容貌老化,恢复容貌美学的方法和临床效果.方法 术前根据性别、年龄、个体容貌特征、受术者的愿望等设计标画填充区域.采用低压肿胀脂肪抽吸技术抽自体躯干部皮下脂肪,将所抽取的自体脂肪颗粒经过清洗、静置、提纯后多层次多隧道均匀注射于容貌有待改善的标记区域,以补充软组织容量,改善老化面容,恢复圆润、流畅的面部轮廓曲线.结果 所有受术者随访3个月至2年,容貌改善满意,无脂肪液化、硬结等并发症发生,其中部分进行再次补充移植,最终效果良好.结论 自体脂肪颗粒注射移植是一项安全、有效的面部软组织缺损填充技术,可以显著地改善面部软组织容积缺损及老化的容貌形象,恢复自然、年轻、优美的容貌美学轮廓,值得临床推广应用.     

自体脂肪颗粒移植矫治颜面部吸脂术后凹陷畸形

目的：探讨应用自体脂肪颗粒移植矫治面部吸脂不当造成的术后凹陷畸形。方法：采用注射器法抽取大腿内侧部脂肪,清洗、纯化成脂肪颗粒后超量30%注射移植于整形术后的凹陷区。结果：本组共13例,11例一次注射充填后形态满意,2例由于凹陷较深,行二次注射。术后随访3个月～2年,未发现有术后感染、组织坏死、液化等并发症。其中10例就医者有回馈资料,反映治疗效果满意。凹陷部位畸形消失,外观平整、轮廓自然,局部无硬结,未触及移植物界限。结论：自体脂肪颗粒移植矫治颜面部吸脂不当导致的术后凹陷畸形方法可行,并发症少,值得临床推广。     

自体脂肪颗粒面部移植术

目的 探讨自体脂肪颗粒面部移植填充的临床效果.方法 选择大腿后外侧作为供区,用注射器低负压法抽取自体脂肪颗粒,离心纯化后,采取多点、多层次的方式在受区进行注射移植.自2008年9月至2011年9月,共对78例患者行面部脂肪注射填充.结果 本组共78例患者,术后随访3～12个月,所有患者面部轮廓和软组织充盈度得到了很好的改善,而且,注射区域的皮肤质地也得到极大的改观.结论 自体脂肪颗粒注射移植是一种较理想的面部软组织填充方法,值得临床推广.     

Lip and Perioral Enhancement by Direct Intramuscular Fat Autograftingrid=""id=""This paper was presented at the XIV Congress of the International Society of Aesthetic Plastic Surgery in São Paulo, May 31–June 3, 1997

Extensive fat resorption when injected subcutaneously was proven a long time ago, as well as central fat necrosis when injected in bulk. On the other hand, direct intramuscular fat injections in the form of 1- to 2-mm threads allow good revascularization and thus proper taking of the graft with minimal resorption. Following that principle, a 2-year follow-up showed less than 20% resorption in our cases. Adipose tissue was obtained by superficial syringe liposuction from the lower abdomen or subgluteal region, or from facial subdermal collections, and then gently cleansed from the blood and local anesthetics with large quantities of a warm physiological solution. Using a strong injector with 1.5- to 2-mm blunt cannulas, the fat was injected during withdrawal in the form of very thin threads directly into the orbicular muscle to correct thin lips. To correct a bony appearance of the face, larger quantities of fat, up to 15 ml, were injected into the buccinator and zygomaticus muscles, while 5–7 ml was injected into the conjunction of the orbicularis oris, depressor anguli oris, and risorius muscles in order to elevate the corners of the mouth.     

Fat transplantation for soft tissue augmentation in the lower limbs

Attempts at fat transplantation in humans began as early as 1893 with Neuber [1] and came to the fore again with the introduction of liposuction. In his 1988 paper, titled ``Present Results of Fat Injections,' Illouz [2] concluded that permanent results were achieved in only 20 to 30% of cases. Numerous other authors also reported poor outcomes. The uniform conclusion of almost all the authors was that the outcome was the result of the common method they followed, that is, injecting fat subcutaneously. However, the poor perfusion of the subcutaneous tissue does not appear to be adequate for the timely revascularization of adipocytes. Around 1983 Jose Guerrerosantos [3,4] successfully injected fat intramuscularly in guinea pigs. Subsequent removal and histological examination of the grafts demonstrated revascularization and almost-complete survival of adipocytes, presumably due to the rich perfusion of the muscle.     

The Role of Frozen Storage in Preserving Adipose Tissue Obtained by Suction-Assisted Lipectomy for Repeated Fat Injection Procedures

BACKGROUND: The injection of autologous free fat obtained by suction-assisted lipectomy for the correction of soft tissue defects is a common procedure in plastic surgery. However, unpredictable partial absorption of the injected fat often necessitates repeated procedures. OBJECTIVE: To examine the role of frozen storage as a means of preserving the fat obtained by suction-assisted lipectomy for repeated procedures. METHODS: Human adipose tissue obtained by suction-assisted lipectomy was stored in a domestic refrigerator at -18 degrees C for 2 weeks. After thawing, the fat was injected into nude mice. In the control group, the fat was injected immediately after the harvesting procedure. Grafts were dissected out and compared 15 weeks postinjection. RESULTS: Injected fat survived in both study and control groups. No significant differences were found between fat graft weight and volume, or in any of the histologic parameters examined. CONCLUSION: Fat obtained by suction-assisted lipectomy may be preserved for future use by freezing.     

Fat partitioning of lidocaine in tumescent liposuction

Despite the fact that toxicity is associated with tumescent liposuction, even with large quantities of injected lidocaine, no study to date has quantitated the percentage of injected lidocaine removed by aspiration, or the quantity partitioned into the aspirated fat. The aim of this study was to quantitate, on a mass basis, the percentage of injected lidocaine removed by aspiration both in the fat as well as the fluid component of the aspirate. Eight consecutive patient aspirate samples were analyzed as part of an ongoing study. An in vivo partition coefficient of lidocaine in fat vs. fluid was derived that suggests that the lidocaine diffuses preferentially into the fat matrix prior to suctioning. A distribution factor was derived that relates the effective aspirate concentration to the instilled concentration, allowing an estimate of lidocaine recovery based on the amount injected.     

Long-term survival of free fat grafts in muscle: An experimental study in rats

In this study, we showed both macroscopically and microscopically the viability of the autotransplanted fat placed intramuscularly in long-term follow-up. The study was performed on 120 Wistar rats during a 12-month period. The fat grafts were obtained from either the inguinal region or preurinary bladder cavity. Rats were divided into six groups. In group 1, the fat was injected in thin rolls in the frontal subcutaneous layer. In group 2, the fat was injected in thin rolls in the gluteus superficialis, biceps femoris, gastrocnemius, and semitendinosus muscles. In group 3, 6 mm × 2 mm fat strips were placed subcutaneously in the frontal region. In group 4, the same dimension of fat strips were placed in the gluteus superficialis and biceps femoris muscles. In group 5, large cystic spaces of fat were injected subcutaneously in the frontal region, and in group 6, large cystic spaces of fat were injected intramuscularly. Rats at 3, 6, 9, and 12 months after fat grafting were sacrificed in order to carry out the macroscopic observations. The results showed clinical and microscopic success in groups 2 and 4, and problems and failure with the remaining groups.Presented at the XI^th Biennial Congress of the International Society of Aesthetic Plastic Surgery in Guadalajara, Jalisco, México, on 3 March 1992     

自体脂肪颗粒移植修复颞部凹陷

目的探讨自体脂肪颗粒移植充填先天性颞部凹陷畸形的临床效果。方法采用注射器法抽取自体脂肪颗粒,经清洗后植入颞部。由于脂肪颗粒移植后有部分被吸收,一般每次超量注射20％。结果共充填修复颞部凹陷152例,1次充填者139例,2次充填者9例,3次充填者4例;每次每侧注射脂肪颗粒6～28ml;疗效满意。结论自体脂肪颗粒移植是治疗先天性颞部凹陷畸形的一种安全有效的方法。     

Contribution of vitamin C administration for increasing lipolysis

This experiment was designed to investigate whether addition of vitamin C to the solution used in tumescent technique of liposuction might increase lipolysis and whether increased fibrosis might improve skin retraction where liposuction did not work properly and the skin had poor retraction ability. Eighteen Sprague-Dawley rats were used in two groups. Both inguinal fat pads of rats with their vascular structures were elevated and the right inguinal fat pad was injected with 1 cc tumescent solution as a control and the left fat pad with a 1 cc vitamin C-tumescent solution. Histopathological examination showed that all fat pads injected with tumescent solution had normal adipocytes. Those injected with vitamin C-tumescent were shown to have extreme fibrosis and occasional adipocytes.     

Facial Volume Restoration With the Fat Autograft Muscle Injection Technique

BACKGROUND: Fat augmentation of the aging face has been a popular cosmetic procedure for decades. Many consider fat the ideal filler because it is natural, nonallergenic, and readily available. However, longevity and symmetry of the fat graft have been unpredictable. In addition, when large volumes are injected for panfacial correction, prolonged edema for months may result. OBJECTIVE: Roger E. Amar has developed a new technique that is known as fat autograft muscle injection (F.A.M.I.) for fat augmentation. We present our experience in 100 patients who underwent this new method. METHODS: One hundred patients underwent the F.A.M.I. procedure in which fat was injected within the muscles of facial expression. The fat was harvested in an atraumatic and sterile manner. Centrifuged fat was then injected with specific blunt-tipped cannulae for different muscle groups. The majority of patients underwent a partial- versus full-face procedure. RESULTS: Patients were injected with volumes ranging from 3 to 63 cc of centrifuged fat in a single session. There were no complications, and downtime was 5 to 7 days. Patient satisfaction was high. Patients were followed postoperatively for 3 to 6 months. CONCLUSIONS: Facial volume restoration with the F.A.M.I. technique is an artistic and systematic approach for facial volume restoration. It offers the potential for symmetric, long-term results.     

自体颗粒脂肪移植在丰唇中的应用研究

目的:观察自体颗粒脂肪移植丰唇在上下唇的临床效果。方法:局部肿胀麻醉后,利用注射器抽吸腹部或大腿内侧皮下脂肪颗粒,进行离心后,注射填充在上下红唇部。结果,采用自体颗粒脂肪移植治疗薄唇36例,其中5例进行2次填充。其余31例填充1次,均达到理想效果。结论:利用自体颗粒脂肪移植丰唇是一种理想并有效的方法,值得临床推广应用。     

自体脂肪移植在颞部凹陷填充中的应用

目的探讨自体脂肪移植在颞部凹陷填充中的应用。方法采用低压抽吸、低速离心、多点、多隧道、多层次、少量注射(Low-pressure liposuction,Low-speed centrifuge,Multi-points,Multi-tunnels,Multi-layers and Low-amounts injection,3L3M)的自体脂肪移植技术,对36例颞部凹陷患者行多区域脂肪移植。1颞区在皮下层、颞浅筋膜层、肌肉层行填充;2额区在额肌皮下层和额肌下行填充;3眶外侧区于皮下层行极少量的脂肪填充。结果 36例颞部凹陷患者经脂肪填充后外形均有明显改善。随访3~24个月,各填充区外形保持较好,移植脂肪吸收率较低,三方评价满意率分别为83.3%、88.9%及86.1%。结论采用3L3M的自体脂肪移植技术填充颞部凹陷,可以得到满意的效果。