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1.
目的:探讨切除部分悬雍垂肌保留悬雍垂黏膜的UPPP治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效.方法:36例OSAHS 患者随机分为2组,行常规临床检查、经Müller′s试验及X线头影测量明确诊断为腭咽平面狭窄,第1组行保留悬雍垂的H-UPPP,第2组行保留悬雍垂黏膜部分切除悬雍垂肌的UPPP.2组患者均于术前及术后6个月行PSG,填写Epworth嗜睡量表(ESS)及鼾声分级表.结果:AHI,LSaO2,ESS评分及鼾声分级在2组术后均明显改善,差异有统计学意义(P<0.01).第1组和第2组疗效比较差异无统计学意义(t=-0.301,P>0.05).第1组和第2组除在手术前后鼾声分级差异有统计学意义(Z=-2.212,P≤0.05),其余差异无统计学意义.结论:对于单纯腭咽平面狭窄的OSAHS患者行悬雍垂肌部分切除保留黏膜的UPPP,在保证疗效的同时比较可靠地降低了术后患者鼾声响度,同时减少了常规H-UPPP术后可能发生的悬雍垂回缩不良的机率.  相似文献   

2.
目的探讨低温等离子消融结合改良悬雍垂腭咽成形术治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效。方法选取经多导睡眠图检查并确诊的OSAHS的患者53例,用等离子低温消融结合改良悬雍垂腭咽成形术治疗,比较术前和术后3个月呼吸暂停低通气指数、最低血氧饱和度及Epworth嗜睡程度评分以确定疗效。结果术后随访3个月,与治疗前比较,术后3个月呼吸暂停低通气指数(AHI)、最低血氧饱和度(LSaO2)、Epworth嗜睡评分(ESS)差异均有统计学意义(P〈0.05)。结论等离子低温消融结合改良悬雍垂腭咽成形术治疗阻塞性睡眠呼吸暂停低通气综合征近期(3个月)疗效满意。  相似文献   

3.
摘要:目的探讨改良悬雍垂腭咽成形手术对阻塞性睡眠呼吸暂停低通气综合征患者食管压力的影响。方法选取阻塞平面为腭咽部的阻塞性睡眠呼吸暂停低通气综合征患者,术前行上气道-食管压力测定,分析食管压力,行改良悬雍垂腭咽成形术,并于术后6个月复查上气道-食管压力,对测量结果进行对比分析。结果①阻塞性睡眠呼吸暂停低通气综合征患者术前发生呼吸暂停时的最大平均食管压力与术前呼吸紊乱指数(r=0.604)、ESS评分(r=0.763)呈正相关,与术前最低血氧饱和度(r=-0.454)呈负相关,差异具有统计学意义(P<0.05)。低通气时的最大平均食管压力与术前呼吸紊乱指数(r=0.600)、ESS评分(r=0.609)呈正相关,与术前最低血氧饱和度(r=-0.322)呈负相关,差异具有统计学意义(P<0.05)。② 30例患者术后6个月复查上气道-食管压力,发生呼吸暂停时最大平均食管压力、低通气最大平均食管压力、呼吸事件时最大呼吸努力、呼吸努力次数、睡眠呼吸暂停低通气指数及最低血氧饱和度结果术后、术前对比分析差异均具有统计学意义(P<0.05)。结论食管压力可以作为评估阻塞性睡眠呼吸暂停低通气综合征患者术前严重程度的一项参考指标。改良悬雍垂腭咽成形术后患者的食管压力得到一定程度改善,进一步肯定了改良悬雍垂腭咽成形术对改善腭咽阻塞为主的阻塞性睡眠呼吸暂停低通气综合征患者的病情和生活质量各方面有确切疗效。  相似文献   

4.
目的 探讨软腭、舌根舌体低温等离子消融配合咽黏膜减张缝合治疗中、重度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的有效性。方法 38 例中度及42例重度OSAHS患者行软腭、舌根舌体低温等离子消融,将咽腭弓折返减张半荷包式缝合于扁桃体窝内,术前及术后6个月行睡眠监测、爱泼沃斯嗜睡量表(ESS)调查及咽腔测量。结果 80例患者均在术后6个月嗜睡状况改善,咽腔前后径、左右径扩大;睡眠结构得到明显改善。结论 咽黏膜减张缝合有效避免了咽腭弓术后撕裂、咽部黏膜重新松弛塌陷;软腭、舌根舌体低温等离子消融配合是治疗OSAHS的有效方法之一。  相似文献   

5.
目的 探讨应用超声刀进行悬雍垂腭咽成形术(UPPP)治疗阻塞性睡眠呼吸暂停综合征(OSAHS)的效果及应用价值。 方法 将需行UPPP的OSAHS患者随机分成超声刀组(A组)及对照组(B组)各20例。A组在静吸复合麻醉下,应用剪型超声刀进行扁桃体切除及悬雍垂腭咽成形术;B组应用传统方法行扁桃体剥离及悬雍垂腭咽成形术。对比两组患者的术中出血量、手术时间、术后疼痛程度、术后效果以及并发症的情况。结果 A组术中出血量明显少于B组,术时缩短明显,术后疼痛及术后并发症情况差异无统计学意义。结论 超声刀辅助下悬雍垂腭咽成形术术中出血少,手术时间明显缩短。  相似文献   

6.
目的 探讨重度阻塞性睡眠呼吸暂停低通气综合征患者(obstructive slee p apnea hypopne asyndrome,OSAHS)同期行悬雍垂腭咽成形术(uvulopalatopharyngoplasty,UPPP)与颏前移舌骨悬吊术(genioglossusadvancement with hyoid suspension,GAHS)术后嗜睡量表(Epwoth sleepy scale,ESS)的变化特征.方法 18例存在腭舌咽平面阻塞的重度OSAHS患者,同期行UPPP与GAHS手术,术后6个月以后复查嗜睡量表,分析其手术前后相关参数.结果 呼吸暂停低通气指数从(63.83±16.34)次/小时下降到(21.43±20.34)次/小时,微觉醒指数从(55.68±3.73)下降34.08±3.03),P<0.01,Epworth嗜睡评分由术前的(16.11±4.25)下降至术后的(9.56±5.59)(P<0.01).结论 UPPP联合GAHS治疗腭咽及舌咽平面阻塞的重度OSAHS患者,其ESS评分明显降低.  相似文献   

7.
悬雍垂腭咽成形术(u vulopalatopharyngoplasty,UPPP)是治疗阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndmmes,OSAHS)的重要方法。解剖腭帆间隙,切除黏膜下脂肪组织的手术理念已得到普遍认可,如何缝合术腔,既能扩大咽腔的  相似文献   

8.
目的探讨悬雍垂腭咽成形术(UPPP)联合等离子辅助舌减容术(radiofrequecney tongue base reduction,RTBR)治疗Ⅱ型阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效。方法回顾性分析2012年1月~2017年5月经多道睡眠监测(PSG)、上气道压力测定(AG200)、上气道CT确诊的OSAHS患者164例,所有患者行UPPP联合RTBR术。术后复查多道睡眠监测确定疗效。结果137例患者术后进行了复查。复查时间为2~66个月,平均(13.37±11.95)个月。137例患者中,治愈率14.6%(20/137),显效率23.36%(32/137),有效率30.66%(42/137),总有效率为68.61%(94/137)。结论UPPP联合RTBR术是治疗OSAHS的有效手术方法,复查率低可能导致手术疗效被低估。  相似文献   

9.
目的 评价低温等离子射频术(temperature controUed radiofrequeney,TCRF)和悬雍垂腭咽成形术(uvulopalatopharyngoplasty,UPPP)治疗阻塞性睡眠呼吸暂停低通气综合征(obstructivesleep apnea-hypopnea syndryome,OSAHS)一期患者的手术疗效和术后并发症.方法 选择阻塞性睡眠呼吸暂停低通气综合征FriedmanM临床分期一期患者60例,随机分TCRF术组和UPPP术组,每组各30例.术后6个月行多导睡眠图分析(polysomnography,PSG),然后对两组患者术前术后PSG监测指标及术后并发症进行统计学分析.结果 临床症状的消除和PSG监测结果两组比较无统计学意义.言语功能的改变、腭咽关闭不全严重并发症上两组无明显差异.但在术后疼痛、恢复正常饮食、术后出血、咽部异物感有明显差异.结论 与UPPP术组相比较,TCRF术治疗OSAHS一期患者手术疗效相似,但并发症明显减少.  相似文献   

10.
目的通过前瞻性的病例对照研究探讨精确气道湿化对低温等离子悬雍垂腭咽成形(H UPPP)术后患者伤口出血量、咽痛、黏膜淤血水肿和痰液黏稠度的影响。方法将49例H UPPP患者按随机数字法分为:精确气道湿化组(18例)、氧气雾化吸入组(16例)和对照组(15例)。精确气道湿化组采用AIRVOTM系列呼吸湿化治疗仪雾化吸入,氧气雾化吸入组采用布地奈德混悬液氧气雾化吸入,对照组采用生理盐水行氧气雾化吸入。术后连续3 d对患者伤口出血量、咽痛、黏膜淤血水肿情况和痰液黏稠度进行评估。结果精确气道湿化组和氧气雾化吸入组患者术后第2天、第3天咽痛均较对照组明显改善(P<0.01),且精确气道湿化组术后黏膜淤血水肿及痰液黏稠度改善均明显好于氧气雾化吸入组(P<0.05)和对照组(P<0.05)。结论精确气道湿化可显著减轻H UPPP术后伤口疼痛、改善黏膜淤血水肿和痰液黏稠度,促进患者早期恢复。  相似文献   

11.
目的:比较保留软腭和部分悬雍垂的改良UPPP与传统UPPP治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的疗效。方法:选择OSAHS患者85例,分别采取改良UPPP(44例)与传统UPPP(41例),全部病例术后随访6个月和1年,比较其疗效。结果:术后6个月,改良UPPP总有效率56.82%(25/44),传统UPPP总有效率58.54%(24/41),但差异无统计学意义(P〉0.05)。鼻咽返流等并发症发生率改良UPPP为36.36%(16/44),传统UPPP68.29%(28/41),差异有统计学意义(P〈0.05)。术后1年,改良UPPP总有效率47.73%(21/44),传统UPPP组总有效率46.34%(19/41),但差异无统计学意义(P〉0.05)。鼻咽返流等并发症发生率前者为27.27%(12/44),后者73.17%(30/41),差异有统计学意义(P〈0.05)。结论:对口咽部阻塞为主的OSAHS患者采用改良的UPPP能取得和传统的UPPP治疗相同的疗效,能相对减少各种并发症的发生。  相似文献   

12.
Conclusions: The efficacy of uvulopalatopharyngoplasty (UPPP) can be achieved without application of an apposition suture of the palatopharyngeal arch and the palatoglossal arch. Objective: To compare the outcomes of two different methods of pharyngeal cavity reconstruction in UPPP. Methods: Forty-eight patients with obstructive sleep apnoea syndrome (OSAS) underwent UPPP (uvula-preserving). A classical pharyngeal cavity reconstruction was performed in 24 patients in group one, with plastic suture of the inferior nasopharynx and exposure of the tonsillar fossa in 24 patients in group two. The parameters evaluated were the subjective symptom score, the Epworth Sleepiness Scale (ESS), and polysomnography result. The mean operating times and complications of the post-operative pharyngeal cavity were investigated. Results: No significant difference was observed in surgical success (p?=?0.54), subjective syndromes (snoring, sleep apnoea, morning headache, daytime sleepiness) (p?=?0.16, 0.36, 0.79 and 0.52), ESS (p?=?0.41), apnoea-hypopnoea index (AHI) (p?=?0.32), and minimum SaO2 (p?=?0.13) between the two groups. In group one, the mean operating time was 54.72?±?6.52?min, 11 suture dehiscence (45.8%), and five scar hypertrophy of the pharyngeal wall (20.8%) were observed post-operatively; while in group two was 38.78?±?5.75?min, no suture dehiscence resulting from suture cutting of tissue, three scar hypertrophy were observed (12.5%).  相似文献   

13.
OBJECTIVE: To explore the relationship between the extent of enlarged oropharynx and efficiency through measuring the anterior-posterior and transverse diameter of oropharynx of patients with obstructive sleep apnea-hypopnea syndrome (OSAHS) before and after uvulopalatopharyngoplasty (UPPP). METHODS: Thirty eight patients with OSAHS were studied. The following indexes were measured before and after UPPP: width of uvula base, length of uvula, distance between uvula and posterior pharyngeal wall (DBUP), distance between anterior pillar (DBPP), apnea-hypopnea index (AHI), body mass index (BMI) and SaO2. RESULTS: The preoperative DBAP and DBPP were significantly less than those of normal adults (P < 0.05). DBUP, length of uvula and width of uvula base has no significant difference between preoperative patients and normal adults (P > 0.05). There was no significance difference in DBAP. DBPP and DBUP between postoperative patients and normal adults (P > 0.05). The preoperative AHI, IBM, minimal SaO2, mean SaO2, DBUP, DBPP, DBAP, length of uvula and width of uvula base has no significant difference between good responders and nonresponders (P > 0.1). CONCLUSIONS: Transverse diameter of OSAHS patients is shorter than that of normal adults but anterior-posterior diameter of OSAHS patients has no difference compared with normal adults. Transverse diameter could be enlarged by UPPP. Not only anatomical abnormality but also other factors will contribute to the effect of UPPP.  相似文献   

14.
目的:改进经典的UPPP手术方法,探讨治疗阻塞性睡眠呼吸暂停低通气综合征(OSAHS),减少术后并发症的方法。方法:对49例OSAHS患者行改良UPPP;术后6、12、24个月随访,每次随访均行PSG测定。参照杭州会议(2002年)标准评定疗效。结果:患者打鼾、憋气、头痛及嗜睡等症状均于6个月内明显减轻或消失,经PSG监测,总有效率为100%。术后12、24个月经PSG监测,其疗效分别为95.92%和91.84%。结论:此术式可有效地扩大腭咽腔的通气面积,保持软腭的紧张度及咽黏膜的正常功能;术后并发症少,治疗效果良好。  相似文献   

15.
目的 探讨阻塞性睡眠呼吸暂停低通气综合征 (obstructivesleepapnea hypopneasyndrome ,OSAHS)患者口咽腔扩大的程度与疗效的关系。方法 对 38例OSAHS行悬雍垂腭咽成形术 (uvulopalatopharyngoplasty ,UPPP)的病例进行手术前后口咽腔测量 :悬雍垂基底宽、悬雍垂长、悬雍垂至咽后壁间距、腭舌弓间距和腭咽弓间距。并观察呼吸暂停低通气指数 (apnea hypopneaindex ,AHI)、体块指数 (bodymassindex ,BMI)、血氧饱和度 (oxygensaturation ,SaO2 )的变化。结果 OSAHS患者手术前的腭舌弓间距和腭咽弓间距比对照组窄 (P <0 0 5 ) ,而至咽后壁的距离 ,悬雍垂长、宽两组数据间差异无显著性 (P >0 0 5 )。手术后腭舌弓间距、腭咽弓间距、至咽后壁的距离与对照组比较差异无显著性 (P >0 0 5 )。有效组和无效组比较 ,手术前呼吸暂停低通气指数、体块指数、最低SaO2 、平均SaO2 、悬雍垂至咽后壁间距、腭舌弓间距和腭咽弓间距、悬雍垂长、宽在统计学上差异无显著性(P >0 1)。结论 OSAHS患者的口咽部左右径小于健康人 ,而前后径与健康人相近。UPPP手术可以显著扩大咽腔口咽部左右径 ,达到健康人水平。UPPP手术疗效不仅仅与解剖结构异常有关 ,还存在其他影响因素  相似文献   

16.
The aim of this study was to determine the associated factors affecting the outcome of uvulopharyngopalatoplasty (UPPP) in patients with severe obstructive sleep apnea hypopnea syndrome (OSAHS), and to investigate whether cephalometric measurements were predictive of the therapeutic response to UPPP in patients with severe OSAHS. We retrospectively studied 51 consecutive patients who underwent revised UPPP with uvula preservation (H-UPPP), or Z-palatopharyngoplasty (ZPPP) for severe OSAHS [apnea–hypopnea index (AHI) >30]. All patients were evaluated using physical examination, Epworth Sleepiness Scale (ESS), cephalometry, and nocturnal polysomnography (PSG) before surgery and at 6–12 months after surgery. Based on the success criteria defined as an AHI of <20 and a decrease >50 %, the overall success rate was 45.1 %. The preoperative distance from the posterior border of the uvula to the middle pharyngeal wall (U-MPW) was significantly longer in the responder group than in the nonresponder group, when considering the whole group or the H-UPPP group alone. Among all study subjects, U-MPW and change in body mass index (△BMI) were the significant predictors of surgical success. U-MPW was the key predictor for H-UPPP surgical success, whereas mandibular plane angle (MPA) and Friedman stage were the key predictors for ZPPP surgical success. In conclusion, U-MPW was a significant predictor of UPPP surgical success. Patients with U-MPW >10 mm who are unwilling to receive nasal continuous positive airway pressure (CPAP) therapy might be suitable candidates for UPPP surgery.  相似文献   

17.
目的 探讨腭咽成形术后锻炼咽腔与颏舌肌对阻塞性睡眠呼吸暂停低通气综合征(OSAHS)疗效的影响。方法 2018年1月—2020年6月将收治的80例行腭咽成形术的OSAHS患者采用数字随机表法分为两组,每组各40例;A组实施改良悬雍垂腭咽成形术治疗,B组在手术治疗基础上进行咽腔与颏舌肌锻炼,比较两组的总有效率、睡眠呼吸暂停低通气指标、睡眠状况指标及生活质量评分。结果 B组的总有效率为92.50%,高于A组75.00%(P<0.05)。治疗后,B组的夜间血氧饱和度高于A组(P<0.05),B组的低通气指数、呼吸暂停指数、呼吸暂停低通气指数均低于A组(P<0.05),B组的实际睡眠时长较A组更长(P<0.05),B组的匹兹堡睡眠质量指数(PSQI)评分较A组更低(P<0.05),B组的生活质量评分高于A组(P<0.05)。结论 在手术基础上采取咽腔与颏舌肌锻炼方法对OSAHS进行治疗可有效减轻患者夜间睡眠呼吸暂停低通气状况,改善其睡眠状况,使其生活质量提升,疗效显著。  相似文献   

18.
ObjectivesTo investigate the surgical outcomes of different uvulopalatopharyngoplasty (UPPP).Methods All subjects underwent overnight polysomnography and were evaluated using the Epworth sleepiness scale (ESS), the Quebec sleep questionnaire and the snoring scale at the baseline and 3 and 12 months following operation. The primary endpoint was the overall effective rate representing the sum of the surgical success rate and effective rate.ResultsThe overall effective rate at 12 months post surgery was 55.6% for simple UPPP, 95.8% for UPPP+GA, and 92.3% for UPPP+TBA. The surgical success rate at 3 and 12 months postoperation for UPPP+GA or UPPP+TBA was significantly higher than simple UPPP (P<0.05). Marked improvement was observed in all patients in the snoring scale score and the ESS score 3 and 12 months following surgery compared to the baseline (P<0.05 in all).ConclusionUPPP, UPPP+GA, and UPPP+TBA are all effective in improving the surgical outcome of obstructive sleep apnea hypopnea syndrome (OSAHS) patients with multilevel obstruction. UPPP+TBA appears to be the most effective in treating OSAHS patients.  相似文献   

19.
:目的比较Z型腭咽成形术(Z uppp)和改良悬雍垂腭咽成形术(H uppp)对不同分度扁桃体肿大及重度阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者选择性治疗的临床疗效。方法选择2015年2月~2016年2月收治的有不同分度扁桃体肿大及重度OSAHS患者82例,随机或按患者要求分成两组,其中40例患者采用Z uppp手术为主的综合治疗,42例患者采用H uppp手术治疗为主的综合治疗。全部病例术后随访1年,比较其疗效。结果术后1年,38例Ⅰ度扁桃体肿大、重度OSAHS患者Z uppp术后总有效率为76.5%,H uppp术后总有效率为35.5%,前者总有效率明显好于后者,经比较差异有统计学意义(P<0.01)。术后1年,44例Ⅱ度及Ⅲ度扁桃体肿大、重度OSAHS患者Z uppp术后总有效率分别为76.7%、82.9%,H uppp术后总有效率分别为68.9%、75.5%,两者比较差异无统计学意义(P>0.05)。结论对于Ⅰ度扁桃体肿大、重度OSAHS患者Z uppp术式长期效果好于H uppp,而Ⅱ、Ⅲ度扁桃体肿大、重度OSAHS患者两种术式长期效果差异不明显。  相似文献   

20.
目的 探讨舌骨甲状软骨悬吊联合悬雍垂腭咽成形术(uvulopalatopharyngoplasty,UPPP)治疗重症阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)的手术方法和效果.方法 对69例有舌咽平面和腭咽平面狭窄的重症OSAHS患者[呼吸暂停低通气指数(apnea hyponea index,AHI)>30次/h]进行了舌骨甲状软骨悬吊联合悬雍垂腭咽成形术.61例完成术后6个月随访,48例完成术后12个月随访.比较手术前后睡眠呼吸监测结果和Epworth嗜睡量表评分.结果 69例患者手术后打鼾症状减轻或消失.术后6个月18例纤维喉镜观察发现,12例患者的腭咽平面和舌咽平面狭窄减轻,6例没有明显变化,但没有舌根后坠.1年后14例纤维喉镜观察未发现狭窄加重者.以AHI降低幅度≥50%为治疗有效的评定标准,术后6个月和12个月随访,有效率分别为78.7%(48/61)和75.0%(36/48);患者AHI平均值由44.8次/h降至15.1次/h和17.2次/h,最低动脉血氧饱和度平均值由0.512升至0.880和0.730,配对t检验,差异均有统计学意义(P值均<0.01);Epworth嗜睡量表评分平均值分别为6.7和7.2分,均较术前的16.6分明显降低(P值均<0.01).结论 舌骨甲状软骨悬吊联合悬雍垂腭咽成形术方法简单,时间短,花费少,手术效果满意,适用于腭咽平面和舌咽平面狭窄的OSAHS患者的治疗.
Abstract:
Objective To discuss the methodology and therapeutic effect of hyoid suspension in association with uvulopalatopharyngoplasty ( UPPP) in the treatment of severe obstructive sleep apnea hypopnea syndrome (OSAHS).Methods Sixty-nine patients with severe OSAHS( apnea hyponea index,AHI > 30) were treated with hyoid suspension and UPPP.Sixty-one patients were followed for 6 months (48 of them for 12 months).Polysomnogram (PSG) tests were performed and an Epworth sleepiness scale ( ESS) was recorded preoperatively and postoperatively in these patients.Results After the surgery,the snoring of the patients disappeared or was alleviated to varing degrees.Eighteen patients underwent fiberoptic nasopharyngolaryngoscopic examination.Twelve of them showed palatopharyngeal and glossopharyngeal stenosis was improved 6 months after surgery.Six patients showed no change,but had no glossoptosis.Fourteen patients underwent fiberoptic nasopharyngolaryngoscopic examination 1 year after surgery,with no recurrence of the stenosis being found.A decrease of 50% in the AHI was considered effective,and in patients the effective rate was 78.7% (48/61 ) 6 months after the operation and 75.0% (36/48) 1 year after the operation.The average AHI decreased from 44.8 to 15.1 and 17.2,and the minimum arterial oxygen saturation average increased from 0.512 to 0.880 and 0.730.Matching t tests were utilized and the results of follow-up indicated that there was a significant improvement in the indexes in those cases which could be followed up ( P < 0.01 ).The average of the ESS was 6.7 six months after operation and 7.2 one year after operation,with a significant decrease compared to the preoperative ( 16.6) data (P <0.01).Conclusions Modified hyoid suspension in association with UPPP has the advantage of a simple operation,short hospitalization and less expense,and the effect of the operation was significant.Patients with palatopharyngeal and glossopharyngeal stenosis should be chosen for this operation.  相似文献   

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