益气活血经验方加减对糖尿病周围神经病变病人血糖、血脂及神经传导速度的影响

目的观察益气活血经验方加减对糖尿病周围神经病变病人血糖、血脂及神经传导速度的影响。方法选取2012年3月我院收治的—2015年3月126例糖尿病周围神经病变病人,分成观察组与对照组,每组63例。对照组采用常规西医治疗,观察组在对照组基础上加用益气活血经验方治疗,治疗8周后观察两组血糖、血脂水平变化,比较两组临床疗效。结果治疗8周后,对照组显效率28.57%、总有效率74.60%,观察组显效率47.62%、总有效率90.48%,观察组显效率、总有效率显著高于对照组(P0.05);两组治疗8周后空腹血糖(FPG)、餐后2 h血糖(2 hPG)、糖化血红蛋白(HbA1c)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)均显著低于治疗前,而高密度脂蛋白胆固醇(HDL-C)显著高于治疗前(P0.05),治疗8周后观察组血糖、血脂指标改善程度显著优于对照组(P0.05);观察组治疗8周后双侧正中神经、胫后神经传导速度均显著高于治疗前(P0.05),且观察组显著优于对照组(P0.05)。结论益气活血经验方能显著改善糖尿病周围神经病变病人血脂水平,提高临床疗效。     

超声引导经皮硬化和引流治疗胰腺假性囊肿

超声引导经皮抽液,四环素硬化治疗和引流治疗胰腺假性囊肿国内外尚未见报道。本文报道8例成功治疗的经验,旨在探讨其临床应用价值。     

自发性移植肾破裂治疗体会

对36例自发性移植肾破裂患者的治疗情况进行回顾性分析。22例采用手术治疗（14例于破裂口填塞明胶海绵或自体脂肪后缝合。8例切除移植肾）,14例保守治疗。认为随着保守治疗经验的积累和治疗成功率的提高,应尽可能避免二次手术切除移植肾,以保守治疗为主。     

48例肺部炎性假瘤患者内科治疗体会

目的总结肺部炎性假瘤的临床诊治经验。方法分析我院呼吸内科收治48例肺部炎性假瘤临床资料。结果48例肺部炎性假瘤病人中,最终外科手术治疗23例(47.9%),放弃治疗8例,内科治疗17例(35.4%),其中病灶吸收明显者8例,病灶略有吸收者5例,病灶增大者4例。结论外科手术应为肺部炎性假瘤首选治疗方案;内科治疗可能有效,对于拒绝手术或无手术指征的患者可能为一种有效的选择。     

心脏程序电刺激诊断预激综合征的价值

本文总结了8年来应用电生理技术诊治147例WPW病人的经验,认为心程刺在附加旁路定位、定量、终止心律失常、筛选药物、确定手术和起搏治疗等方面具有重要的意义。     

重症COPD急性加重期的救治体会

重症 COPD急性加重期进展凶险 ,病死率高。本文回顾了2 0 0 2年 1月至 2 0 0 3年 3月我科 RICU病房的重症 COPD急性加重患者 2 2例的救治经过 ,总结了治疗经验 ,现报道如下。1　资料和方法1.1　一般资料　本组 2 2例 ,男性 14例 ,女性 8例 ;年龄 5 8～84岁 ,其中 5 8～ 70岁 12     

导管介入术后假性动脉瘤的早期诊断及治疗

假性动脉瘤是导管介入术后常见并发症 ,及早发现可避免外科创伤性修复 ,本文总结了我院经导管介入术后出现的 1 8例假性动脉瘤的诊治经验。1　对象与方法　　自 1 994年 4月～ 2 0 0 2年 4月我院共有 30 5 0例患者接受经股动脉行心脏介入检查及治疗 ,穿刺采用Seldinger法 ,发现假性动脉瘤 1 8例 ( 0 .5 9% ) ,其中男 1 4例 ,女 4例 ,年龄 5 0～ 78( 64.3± 8.9)岁。1 8例患者中 9例穿刺点在股浅动脉 ,6例经同一动脉行 2次或以上介入检查及治疗。 1 8例均选用重复绷带加压法 :患者平卧重新压迫股动脉穿刺处 2 0min ,按压程度患者可耐受 ,穿…     

经验调经汤加减治疗月经不调的疗效分析

目的观察经验调经汤加减治疗月经不调患者的疗效。方法选取2015年5月~2016年2月我院收治的月经不调患者98例作为研究对象,根据中西医药治疗方案的不同分为西医组与中医组,各49例。西医组的患者均采用常规性的西药药物进行月经不调的治疗,而中医组的患者均进行经验调经汤的加减治疗方案,对比两组的月经不调治疗疗效。结果西医组中痊愈患者8例,显效12例,有效17例,无效12例,西医治疗的总有效率为75.51%(37/49);而中医组的患者中痊愈22例,显效16例,有效9例,无效2例,中医治疗的总有效率为95.92%(47/49)。得知,两组治疗疗效比较,差异有统计学意义(P0.05)。结论经实践对比分析可知,经验调经汤加减治疗月经不调的临床总有效率非常高,疗效明显确切,值得对月经不调患者进行推广此疗法的应用。     

168例术后伤口龟分枝杆菌感染的治疗与随访观察

目的　总结术后伤口龟分枝杆菌感染的治疗经验。方法　回顾 16 8例非结核分枝杆菌 (NTM)伤口感染患者诊断、治疗及 4年半以来随访情况。根据药敏试验结果 ,抗生素治疗以克拉霉素及丁胺卡那为主 ,疗程 4～ 8个月。其中 10 4例患者在抗生素治疗 1个月后实施根治性病灶切除手术 ,术后继续抗生素治疗 3～ 5个月。结果　抗生素治疗加外科根治性病灶切除 10 4例 ,其中 98例伤口Ⅰ期愈合 ;5 0例用抗生素治疗加伤口换药而治愈 ;8例仅伤口换药 ,未用抗生素治愈 ;5例小儿包皮环切后NTM感染者经抗生素治疗加局部激光治疗而治愈 ;1例疝手术后感染者以丁胺卡那作病灶周围封闭治愈。所有病例经随访 4年半 ,无一例复发。结论　采用敏感抗生素系统治疗加外科根治性病灶切除是NTM伤口感染治疗的重要手段。     

谷维素与吡喹酮配伍治疗慢性结肠血吸虫病肠功能紊乱8例

根据张兴文报告的谷维素临床新用途,笔者结合报道所介绍的经验,用谷维素与吡喹酮配伍治疗慢性结肠血吸虫病肠道功能紊乱8例,获得满意疗效。一、临床资料 1、一般资料: 本组病例男5例,女3例,年龄31～52岁,有明确的血吸虫病疫水接触史,尼纶绢集     

Primary omental malignant solitary fibrous tumour,an extremely rare malignancy: A case report and review of the literature

Primary omental malignant solitary fibrous tumour is an extremely rare neoplasm considering its tumour origin and pathologic characteristics. Solitary fibrous tumour (SFT) is a spindle cell neoplasm that was first described in 1931. SFT is diagnosed at immunohistochemical stain including CD34, bcl2, CD99 and STAT6. Though most of SFTs are benign in nature, 5–15% are malignant. The diagnostic criteria of malignant SFTs are high cellularity, high mitotic activity(>4/10HPF), pleomorphism, necrosis and haemorrhage.We present the case of a 57-year-old male patient diagnosed with primary omental malignant SFT. Neither tumour origin nor pathologic diagnosis were possible based on preoperative information. Nevertheless, tumour resection was performed successfully.Several SFT cases involving omentum without malignant potential have been reported. However, primary omental malignant SFTs are extremely rare with only 3 cases reported in the literature.     

人工假体置换治疗股骨上段骨肿瘤

采用全股骨及半股骨人工假体置换治疗股骨上皮骨肿瘤21例，男13例，女8例．其中骨肉瘤4例（3例为皮质分骨肉瘤），软骨肉瘤9例。骨巨细胞瘤7例，恶性纤维组织细胞瘤1例。经1～17年的随访观察，收到了满意治疗效果。作者认为：术中遵守无瘤手术操作、彻底切除是降低复发率、转移率的关键；人工假体置技术对于肢体的骨肿瘤、骨巨细胞瘤的治疗效果优于软骨肉瘤，软骨肉瘤的治疗效果优于骨肉瘤.     

Recombinant alpha-2b interferon in patients with malignant carcinoid tumour

Abstract Seventeen patients with malignant carcinoid tumour, ten of whom had the malignant carcinoid syndrome, were treated with recombinant alpha-2b interferon by subcutaneous injection (3 MU per dose) three times per week for a median of 12 weeks (range 4–48). No objective tumour responses were observed; however, there was a greater than 50% reduction in 24-hour urinary 5-hydroxyindolacetic acid (5-HIAA) excretion in four often patients (40%) with elevated pretreat-ment levels. Five often patients (50%) with flushing, five of seven patients (71%) with diarrhoea and both patients with wheezing experienced relief of symptoms. Three of four patients (75%) with weight loss as their only problem experienced weight gain. Responses occurred within the first eight weeks of treatment, but were generally of short duration. Toxicity occurred in all patients, and consisted mainly of fever, chills, anorexia, fatigue and weight loss. Four patients ceased therapy due to toxic reactions. Although interferon has activity against carcinoid tumours, its benefits are short-lived and toxicity limits its use with increasing dose. Patients with carcinoid syndrome appear to achieve the best therapeutic response, and it is likely that low doses (9–20 million IU weekly) are as effective as higher doses (36–72 million IU weekly). (Aust NZ J Med 1991; 21: 875–878.)     

恶性肿瘤并发弓形虫感染的研究

本文采用间接血凝试验(IHA)方法,对75例恶性肿瘤患者,62例普通病人及正常人对照组75例,进行血清弓形虫抗体的检测,以效价≥1:64为阳性。结果表明,恶性肿瘤组感染率为33.3%,普通病人组感染率为11%(P<0.01),正常对照组感染率为5%以下(P<0.001)。以恶性葡萄胎患者感染率最高,达83%;其次为白血病及消化道肿瘤,分别为40%,39%,以上三种肿瘤患者的抗体滴度几何均数(GMT)分别为48.51,63.59和38.1。7例乳腺癌和11例肺癌患者抗体均为阴性。     

肿瘤浸润淋巴细胞治疗老年人恶性胸水的疗效分析

目的探讨肿瘤浸润淋巴细胞（ＴＩＬ）治疗老年癌症患者恶性胸水的有效率。方法应用癌症患者自体胸水的ＴＩＬ培养、扩增后产物经胸腔内输注治疗２１例老年人恶性胸水,每隔日１次,至少４次。结果２１例经治疗后,胸水中淋巴细胞增加,肿瘤细胞逐渐减少,胸腔积液逐渐吸收,１个月后１９例达完全缓解和部分缓解,有效率为９０．５％。结论自体胸水ＴＩＬ可治疗恶性胸水,同时可提高老年癌症患者的免疫功能,对机体无毒副作用。     

PRIMARY ALDOSTERONISM DUE TO A MALIGNANT OVARIAN TUMOUR

Abstract The case of a woman with autonomous aldosteronism, hypertension, and malignant ovarian tumour is reported. Hormone studies revealed high plasma aldosterone levels, and low plasma renin concentration. Following surgical removal of a malignant sex cord stromal tumour, the hyperaldosteronism regressed, and the hypertension improved. Subsequently the tumour recurred, as did hyperaldosteronism.     

老年恶性肿瘤患者血液流变学指标的检测分析

目的分析老年恶性肿瘤患者血液流变学指标的变化及临床意义。方法对136例老年恶性肿瘤病人（转移组52例,未转移组84例）和50例健康人的血液流变学指标进行检测分析。结果老年恶性肿瘤患者全血黏度、血浆黏度、血沉、红细胞压积、红细胞刚性指数、红细胞聚集指数、纤维蛋白原的水平较健康对照组有明显增高,有统计学意义（P〈0．05）,有转移组与无转移组的比较也有统计学意义（P〈0．01）。结论老年恶性肿瘤患者存在明显高凝状态,血液流变学指标可以作为了解老年肿瘤发生和发展的重要指标。     

Serum Creatine Kinase Isoenzymes in Patients with Advanced Malignant Disease

ABSTRACT Serum creatine kinase (CK) B subunit (CK-B) activity, as estimated by the enzymatic anti-M immunoinhibition method, and the CK isoenzyme pattern after agarose gel electrophoresis, were studied in 28 patients with advanced, untreated malignant disease. CK-B was above the decision limit, i.e. the discrimination limit used in the diagnosis of acute myocardial infarction (AMI), in 14 patients (50%). Electrophoresis demonstrated, besides CK-MM, an atypical, cathodically migrating CK band in 10 of these patients. This band may represent mitochondrial CK. The CK-BB isoenzyme was detected in 9 and CK-MB in 3 subjects. Histopathologic findings indicated that the occurrence of these isoenzymes was related to tumour burden and the overall severity of the disease. Survival among patients with CK-B elevation was shorter than among other patients. The present findings are relevant to the enzyme diagnosis of AMI and of potential significance for the evaluation of patients with known or suspected malignant tumours.     

MEDIASTINAL CARCINOID TUMOUR: PRE-OPERATIVE ARTERIAL EMBOLISATION

Carcinoid tumours of the mediastinum are very rare. They are frequently malignant and run a quite different course from that of the more benign thymomas. We report a 70 year old man with an anterior mediastinal tumour which was initially diagnosed as a thymoma but which was subsequently shown to be a carcinoid tumour. Surgical extirpation was greatly enhanced by pre-operative angiography and arterial embolisation of the tumour. Early and aggressive diagnostic attempts, pre-operative angiography, with or without arterial embolisation, and complete surgical excision offer the best hope of a cure for these malignant tumours.     

Askin's tumour in pregnancy with dismal prognosis

Askin's tumour is a rare malignant neoplasm of the chest wall. A 23‐year‐old primigravida patient was admitted to the hospital with complaints of chest wall swelling, cough and dyspnoea. Radiological examination showed a chest wall mass in right hemithorax with erosion of ribs and moderate pleural effusion. Fine‐needle aspiration cytology was suggestive of malignant small round cell tumour. Immunohistochemical analysis together with the clinical and radiological findings led to the definitive diagnosis of Askin's tumour. Despite receiving multimodality therapy, she had residual soft tissue mass and died after 6 months. Rarity of this malignancy during pregnancy renders the case unique.