前节相干光断层扫描技术在角膜外伤中的应用研究

目的评估前节相干光断层扫描技术（AS-OCT）在角膜外伤诊疗中的应用价值。方法回顾性分析85例（91只眼）各类角膜外伤：穿通伤56只眼,钝挫伤18只眼,角膜异物10只眼,化学伤7只眼。所有患者在诊疗过程中除常规裂隙灯显微镜等检查外,均以AS-OCT观察了角膜形态结构,部分患者进行了角膜厚度测量。结果所有病例均获得清晰AS-OCT角膜图像,8只眼角膜穿通伤病例清创缝合术后患眼发现严重角膜伤口内口对合不佳,3只眼LASIK术后眼球钝挫伤发现角膜层间积液,对于透明/半透明角膜异物病例,AS-OCT可显示异物在角膜内具体位置。但对于金属异物,在AS-OCT检查所获图像中异物后的部分呈现为无反射区,故而无法判断异物深度。AS-OCT可清晰显示急性期角膜化学伤患者角膜水肿情况并可进行厚度测量。1只眼因陈旧性化学伤导致的角膜白斑,裂隙灯显微镜下无法窥见眼内结构,AS-OCT显示前房、虹膜结构基本正常。结论 AS-OCT可清晰显示外伤后角膜的形态结构,对于角膜外伤的诊断和疗效评估具有很好的应用价值。     

Comparison of central corneal thickness and anterior chamber depth measurements using three imaging technologies in normal eyes and after phakic intraocular lens implantation

Background  The repeatability and interchangeability of imaging devices measuring central corneal thickness (CCT) and anterior chamber depth (ACD) are important in the assessment of patients considering refractive surgery. The purpose of this study was to investigate the agreement of CCT and ACD measurements using three imaging technologies in healthy eyes and in eyes after phakic intraocular lens implantation (pIOL). Methods  In this comparative study, CCT and ACD were measured using anterior segment optical coherence tomography (AS-OCT), Orbscan II, and Pentacam in 33 healthy volunteers (66 eyes) and 22 patients (42 eyes) after pIOL implantation. Intraobserver repeatability was evaluated for all three devices in the healthy volunteer group. Results  Pairwise comparison of CCT measurements showed significant differences between all devices (P < 0.001), except for the AS-OCT and Orbscan II in the healthy volunteer group (P = 0.422) and the Orbscan II and Pentacam in the pIOL group (P = 0.214). ACD measurements demonstrated significant differences between all pairwise comparisons in both groups (P ≤ 0.001). Intraobserver reliability was high for CCT and ACD measurements in the healthy volunteer group, with coefficients of variation ranging from 0.6% to 1.2% and 0.4% to 0.5% respectively. Conclusions  CCT and ACD measurements using AS-OCT, Orbscan II, and Pentacam demonstrated high intraobserver reliability. However, these devices should not be used interchangeably for measurements of CCT and ACD in healthy subject and patients after pIOL implantation. Financial support  None The authors have no financial or proprietary interest in any aspect of this study and have full control of all primary data, and agree to allow Graefe’s Archive for Clinical and Experimental Ophthalmology to review our data if requested.     

Anterior segment imaging in glaucoma: An updated review

Anterior segment imaging allows for an objective method of visualizing the anterior segment angle. Two of the most commonly used devices for anterior segment imaging include the anterior segment optical coherence tomography (AS-OCT) and the ultrasound biomicroscopy (UBM). AS-OCT technology has several types, including time-domain, swept-source, and spectral-domain-based configurations. We performed a literature search on PubMed for articles containing the text “anterior segment OCT,” “ultrasound biomicroscopy,” and “anterior segment imaging” since 2004, with some pertinent references before 2004 included for completeness. This review compares the advantages and disadvantages of AS-OCT and UBM, and summarizes the most recent literature regarding the importance of these devices in glaucoma diagnosis and management. These devices not only aid in visualization of the angle, but also have important postsurgical applications in bleb and tube imaging.     

Recent advances in optical coherence tomography for anterior segment imaging in small animals and their clinical implications

Anterior segment optical coherence tomography (AS-OCT) is a rapidly evolving area of OCT imaging, providing high-resolution and non-invasive volumetric imaging of the anterior segment. This review focuses on recent advances in AS-OCT imaging in small animals, which we categorize into ultrahigh-resolution, spectroscopic, magnetomotive, polarization-sensitive, and angiographic AS-OCTs. We summarize their technical foundations, review their applications to small animal imaging, and briefly discuss their current and future clinical applications.     

Lanstar900、AS-OCT和A型超声测量中央角膜厚度的分析

目的比较Lanstar900、前节相干光断层扫描（AS-OCT）和A型超声三种角膜测厚仪检测近视眼中央角膜厚度的差异。方法分别用Lanstar900、AS-OCT和A型超声对角膜厚度进行检测,并将测量值进行统计学分析。结果 Lenstar900测得中央角膜厚度为（538.58±25.623）μm;AS-OCT测得中央角膜厚度为（541.96±25.257）μm;A型超声测得中央角膜厚度为（534.93±26.042）μm。两两配对t检验显示,AS-OCT与A型超声测得中央角膜厚度值差异有统计学意义（t=2.252,P=0.013）。AS-OCT与Lenstar900测得中央角膜厚度值差异无统计学意义（t=1.091,P=0.139）。Lenstar900与A型超声测得中央角膜厚度值差异无统计学意义（t=1.161,P=0.124）。三种测厚结果显示高度正相关（P〈0.001）,其中相关系数r最高的是Lanstar900-A型超声为0.988,均高于Lanstar900-AS-OCT的相关系数（0.954）和AS-OCT-A型超声的相关系数（0.953）;从相关系数来看三种仪器的相关程度很高。其回归方程如下：AS-OCT（μm）=35.414＋0.941X Lanstar900（μm）;AS-OCT（μm）=47.750＋0.924X A型超声μm）;Lanstar900（μm）=18.468＋0.972X A型超声（μm）。结论在检测中央角膜厚度方面,三者检测方法有较高的相关性,Lanstar900与A型超声可相互替代使用。     

Anterior Ocular Biometrics Using Placido-scanning-slit System,Rotating Scheimpflug Tomography,and Swept-source Optical Coherence Tomography

PurposeTo compare anterior biometry measurements using placido-scanning-slit topography, rotating Scheimpflug tomography, and swept-source optical coherence tomography.MethodsA retrospective review consisted of 80 eyes of 49 participants who underwent anterior chamber depth (ACD), central corneal thickness (CCT), and keratometry examination on the same day. We used placido-scanning-slit topography (ORBscan II), rotating Scheimpflug tomography (Pentacam HR), and swept-source optical coherence tomography (CASIA SS-1000). The intraclass correlation coefficients and Bland-Altman plots were used to evaluate the agreement and differences between measurements.ResultsThe mean ACD values were 2.88 ± 0.43, 2.82 ± 0.50, and 2.68 ± 0.44 mm; and the mean CCT values were 536.96 ± 31.19, 543.79 ± 31.04, and 561.41 ± 32.60 μm; and the mean keratometry (Km) were 43.81 ± 1.69, 43.81 ± 1.77, and 44.65 ± 1.95 diopters; as measured by CASIA SS-1000, Pentacam HR, and ORBscan II, respectively. Among the three devices, ACD was deepest to shallowest in the order of CASIA SS-1000, Pentacam HR, and ORBscan II (p < 0.05). The CCT was thickest to thinnest in the order of ORBscan II, Pentacam HR, and CASIA SS-1000 (p < 0.05). No significant differences in Km values were examined between CASIA SS-1000 and Pentacam HR, whereas ORBscan II overestimated Km with a statistically significant difference compared to the other two devices.ConclusionsHigh level of agreement was found between CASIA SS-1000 and Pentacam HR for anterior parameters, including ACD, CCT, and Km, suggesting interchangeability. However, ORBscan II measurements differed considerably with the measurements obtained from the other two devices; therefore, it should not be used interchangeably. However, further studies with repeatability test should be considered in order to elucidate the reliability of each device.     

Clinical applications of Scheimpflug imaging in cataract surgery

Since the Scheimpflug principle was first described over a century ago, there has been a great interest among ophthalmologists for the use of Scheimpflug camera in anterior segment imaging. Scheimpflug imaging has since advanced significantly and modern day instruments provide comprehensive imaging and topographic data of the anterior segment. In this article the clinical applications and limitations of Scheimpflug imaging in modern cataract surgery patients are discussed. This article reviews recent work on assessment of lens transparency for cataract grading and integrity, using preoperative lens density measurements to help predict phacoemulsification parameters, its utility in challenging situations like capsular bag distension syndrome and traumatic cataract and assessment of density of the posterior capsule for objectively quantifying posterior-capsule opacification.     

不同角膜测厚法对LASIK术后中央及旁中央角膜厚度测量值的影响及比较分析

背景 准确的角膜厚度测量对准分子激光角膜屈光手术的术前设计及术后随访非常重要,对屈光欠矫及屈光回退的患者能否行二次激光加强手术更是不可或缺的重要检查. 目的 比较OrbscanⅡ眼前节分析仪（OrbscanⅡ）、非接触角膜内皮显微镜、眼前节光学相干断层扫描仪（AS-OCT）和A型超声角膜测厚仪对准分子激光角膜原位磨镶术（LASIK）术后角膜中央和旁中央厚度测量结果的差异. 方法 收集2011年3-6月在河南省眼科研究所＆河南省立眼科医院接受LASIK手术的患者64例64眼（均纳入右眼）,受检者术前平均等效球镜屈光度为（-4.75±2.38）D,平均水平角膜直径为（11.36±0.32）mm,采用OrbscanⅡ、非接触角膜内皮显微镜、AS-OCT和A型超声角膜测厚仪（超声法）分别测量受检眼的中央角膜厚度（CCT）,同时采用OrbscanⅡ、非接触角膜内皮显微镜、AS-OCT 3种非接触角膜厚度测量法测量距角膜中心3 mm区角膜上方（12：00）、下方（6：00）、鼻上方（2：00）和颞上方（10：00）的旁中央角膜厚度,比较不同角膜测厚仪测量结果的差异,评价检测仪器间测量结果的一致性. 结果 CCT测量结果显示,AS-OCT、A型超声角膜测厚仪、非接触角膜内皮显微镜和OrbsanⅡ的测量值分别为（467.12±31.10）、（466.67±30.99）、（441.84±33.65） μm和（422.51±44.09）μm,总体比较差异有统计学意义（F=23.730,P=0.000）;A型超声角膜测厚仪测得的CCT值明显高于OrbsanⅡ和非接触角膜内皮显微镜的结果,差异均有统计学意义（q=6.940、6.720,均P=0.000）;与OrbscanⅡ测量方法比较,非接触角膜内皮显微镜和AS-OCT测量的CCT值明显较高,差异均有统计学意义（q=-5.540、6.940,均P=0.000）,而AS-OCT测量的CCT值明显高于非接触角膜内皮显微镜的测量值,差异有统计学意义（q=6.800,P=0.000）.Bland-Ahman一致性分析结果显示,A型超声角膜测厚仪与AS-OCT?     

Measurement of central corneal thickness by high‐resolution Scheimpflug imaging,Fourier‐domain optical coherence tomography and ultrasound pachymetry

Purpose: To compare the repeatability and reproducibility of central corneal thickness (CCT) measurements by high‐resolution (HR) rotating Scheimpflug imaging and Fourier‐domain optical coherence tomography (FD‐OCT). CCT measurements were compared to those determined by ultrasound pachymetry (UP). Methods: In 35 healthy eyes, intra‐observer repeatability for HR Scheimpflug (Pentacam) and FD‐OCT (RTVue) systems was determined in consecutive images taken by an observer in the shortest time possible. Imaging was repeated again by a second observer to evaluate inter‐observer reproducibility. The CCT measurements were compared among Scheimpflug, FD‐OCT and UP images. Results: Mean coefficients of repeatability were 0.48% for Scheimpflug and 0.26% for FD‐OCT. For Scheimpflug, the coefficient of inter‐operator reproducibility was 0.87%. For FD‐OCT, the coefficient of inter‐operator reproducibility was 0.45%. The CCT measurements by Scheimpflug, OCT and UP images were (mean ± standard deviation) 521.7 ± 27.6 μm, 510.8 ± 28.6 μm and 516.5 ± 27.6 μm, respectively. The differences between instruments were statistically significant. The 95% limits of agreement in CCT were ?0.7 to 22.5 μm for Pentacam‐OCT, ?13.4 to 24.0 μm for Pentacam‐UP and ?26.7 to 15.4 μm for OCT‐UP. There was a high degree of correlation between CCT measured by all 3 methods. Conclusion: Noncontact measurements of CCT with HR Scheimpflug and FD‐OCT systems yielded excellent repeatability and reproducibility and can be used interchangeably. Although both devices were comparable with UP; in clinical practice, the measurements acquired by optical modalities are not directly interchangeable with UP measurements.     

AS-OCT对青光眼滤过术后滤过泡形态及形成过程评估

目的 通过应用眼前节光学相干断层扫描(AS-OCT)对青光眼滤过术后不同时期滤过泡内部结构的观察,了解各种类型滤过泡的内部结构特征和动态变化规律,以期寻找不同形态滤过泡与其功能间关系,为临床诊疗提供客观依据.方法 前瞻性分析研究.对2009年3月至2009年12月在北京大学眼科中心行青光眼滤过手术的患者62例(68只眼),年龄从27 ～ 79岁,平均年龄(62.56±14.06)岁,其中男性26例(29只眼),女性36例(39只眼).在术后1d,1周,1个月,3个月,6个月分别行视力,眼压,裂隙灯显微镜和AS-OCT检查.结果 68只眼中有4只眼在术后6个月时眼压高于20 mm Hg,其余64只眼在随访期间眼压均在正常范围.术后1d至术后6个月,滤过泡的总体高度变化差异无统计学意义(P＞0.05),囊壁厚度逐渐增加(P＜0.05),囊壁回声逐渐增强(P＜0.05).AS-OCT能清晰显示滤过泡的内部结构;量化有效滤过泡的各项指标,包括滤过泡总体高度,囊壁的厚度,巩膜瓣下的滤过通道等;显示滤过手术后不同时期滤过泡的动态变化.结论 AS-OCT是评价青光眼术后滤过泡形态的有效工具.探明滤过泡外观、内部结构及其功能的相互关系,有助于为滤过泡的功能维护提供客观参考.     

Fourier analysis of corneal Scheimpflug imaging: clinical use in keratoconus

AIM: To evaluate the clinical use of Fourier analysis of videokeratography data in the diagnosis and follow-up of keratoconus (KC). METHODS: We conducted a chart review of consecutive patients presented to our cornea clinic. A team of two experienced cornea specialists divided the patients into three groups: normal cornea, forme fruste KC (FFKC), and clinical KC. The exclusion criteria were a history of previous ocular surgery, any accompanying corneal pathology other than KC, high myopia (>6.00 diopters), amblyopia, pregnancy, breastfeeding, or any current autoimmune disease. The data of Fourier series harmonic analysis were evaluated for their diagnostic capacity using the receiver operating characteristic (ROC) curve. A binary logistic regression analysis was also conducted to construct a diagnostic model. A total of 259 eyes showed progression in the clinical KC group and underwent a combination of accelerated corneal collagen cross-linking and topography-guided customized treatment with an excimer laser. RESULTS: The study included 1262 eyes (618 normal, 530 KC, and 114 FFKC) of 1262 patients. We observed that maximum decentration (MaxDec) was almost as good as maximum keratometry (Kmax) in detecting progressive KC. The area under the curve (AUC) was 0.95 for KC [95% confidence interval (CI): 0.93-0.96] and 0.84 for FFKC (95%CI: 0.79-0.88). Higher predictive accuracy was obtained using a model combining the spherical component, MaxDec, irregularity, and regular astigmatism in the center of the cornea (AUC: 0.97; sensitivity: 89%, and specificity: 96%). CONCLUSION: Decentration, Kmax, and posterior radii of curvatures from a 3.0-mm optical zone centered on the thinnest point of the cornea provide the highest accuracy with low reproducibility of Kmax.     

Monitoring of central corneal thickness after phacoemulsification—comparison of statical and rotating Scheimpflug pachymetry,and spectral-domain OCT

AIMTo explore the possibility of deploying three contactless devices (static and rotating Scheimpflug technology, spectral domain optical coherence tomography) for measuring central corneal thickness (CCT) in preoperative and postoperative examinations of cataract patients.METHODSTotally 72 patients who had undergone surgery without complications were selected. The CCT was measured prior to the operation, as well as on the first, 5^th-7^th and 28^th day following the operation using the Nidek NT 530-P, Sirius^®, and Topcon OCT-2000 devices.RESULTSA significant postoperative increase and subsequent decrease in CCT was identified with all three devices. The correlations were highly significant and thus reflect a very good degree of comparability at all times with the exception of the rotating Scheimpflug camera. The postoperative results from the latter differed significantly from the other devices. The correlations were Sirius/Topcon (P=0.010) and Sirius/Nidek (P<0.0005). No statistically significant difference could be identified in the comparison between Topcon and Nidek (P=0.056).CONCLUSIONAll three devices are suitable for postoperative monitoring of CCT. The measurement results are only comparable to a limited extent and not interchangeable in the course of treating a single patient. This is due to the different imaging technology used in the devices and the resulting modalities for conducting the measurements.     

Agreement between Scheimpflug Camera and the Swept-source Optical Coherence Tomography Measurements in Keratometry and Higher-order Aberrations

PurposeTo evaluate the compatibility of corneal curvature and astigmatism, and higher-order aberrations (HOAs) measured by the Scheimpflug camera Pentacam HR and the swept-source optical coherence tomography ANTERION.MethodsThis prospective study included normal subjects with no ophthalmic history. Steep keratometry (K), flat K, astigmatism and its axis of the anterior and posterior surfaces, total corneal power, and HOAs using the two instruments were compared. To compare the mean values of the measurements, a paired t-test was used. Bland-Altman analysis was applied to assess the agreement between the two devices.ResultsFifty-three eyes of 53 subjects were evaluated. There were statistically significant differences for steep K, astigmatism, and vector J0, J45 in the anterior surface and total corneal power between the two devices (p < 0.05). There were also significant differences in the most of the keratometric values of the posterior corneal surface (p < 0.05) except J0 (p = 0.410). Both devices showed strong positive correlations in steep K, flat K, astigmatism (r > 0.81, p < 0.001) with wide ranges of a 95% limit of agreement. Vectoral components were significantly correlated (r > 0.78, p < 0.001) with narrow 95% limit of agreement, except J45 of the posterior surface (r = 0.39, p = 0.004). In the corneal HOAs, there were statistically significant differences in the vertical coma, horizontal trefoil, spherical aberration, and root mean square of each fifth- and sixth-order Zernike coefficient (p = 0.043, p = 0.041, p < 0.001, p < 0.001, and p < 0.001, respectively). Other HOAs showed moderate to strong positive correlations (r > 0.37, p < 0.05). Most HOAs, except for the horizontal trefoil, showed clinically acceptable agreements. The total root mean square of HOAs was not significantly different between the two devices (p = 0.122).ConclusionsMost of the keratometric values cannot be used interchangeably. However, the vectoral component of astigmatism showed clinically good agreement. Several HOAs have statistically significant differences; however, almost all HOAs showed acceptable agreements, except for the horizontal trefoil.     

Estimation of Intraocular Lens Power Calculation after Myopic Corneal Refractive Surgery: Using Corneal Height in Anterior Segment Optical Coherence Tomography

PurposeTo investigate the feasibility of estimating effective lens position (ELP) and calculating intraocular lens power using corneal height (CH), as measured using anterior segment optical coherence tomography (AS-OCT), in patients who have undergone corneal refractive surgery.MethodsThis study included 23 patients (30 eyes) who have undergone myopic corneal refractive surgery and subsequent successful cataract surgery. The CH was measured with AS-OCT, and the measured ELP (ELP_m) was calculated. Intraocular lens power, which could achieve actual emmetropia (P_real), was determined with medical records. Estimated ELP (ELP_est) was back-calculated using P_real, axial length, and keratometric value through the SRK/T formula. After searching the best-fit regression formula between ELP_m and ELP_est, converted ELP and intraocular lens power (ELP_conv, P_conv) were obtained and then compared to ELP_est and P_real, respectively. The proportion of eyes within a defined error was investigated.ResultsMean CH, ELP_est, and ELP_m were 3.71 ± 0.23, 7.74 ± 1.09, 5.78 ± 0.26 mm, respectively. The ELP_m and ELP_est were linearly correlated (ELP_est = 1.841 × ELP_m - 2.018, p = 0.023, R = 0.410) and ELP_conv and P_conv agreed well with ELP_est and P_real, respectively. Eyes within ±0.5, ±1.0, ±1.5, and ±2.0 diopters of the calculated P_conv, were 23.3%, 66.6%, 83.3%, and 100.0%, respectively.ConclusionsIntraocular lens power calculation using CH measured with AS-OCT shows comparable accuracy to several conventional methods in eyes following corneal refractive surgery.     

Anterior segment parameters using Pentacam and prediction of corneal endothelial cell loss after cataract surgery

Purpose

We evaluated various preoperative anterior segment parameters measured with a Pentacam rotating Scheimpflug camera and compared them with those of conventional methods. We also evaluated the effect of different parameters on corneal endothelial cells after cataract surgery.

Methods

Pentacam examination was performed in 88 eyes from 88 patients to evaluate central anterior chamber depth (ACD_pentacam), nuclear density (Densitometry_pentacam), anterior chamber volume (ACV), and lens thickness (LT_pentacam). We compared values of ACD_pentacam with those of ultrasound (ACD_sono) and also compared Densitometry_pentacam values with those of Lens Opacities Classification System (LOCS III) classification. We evaluated the effect of the following preoperative values measured with Pentacam on postoperative endothelial cell loss: pupil size measured both preoperatively and before capsulorrhexsis (Pupil_CCC), amount of viscoelastics, and LT measured by ultrasound (LT_sono).

Results

A significant concordance was found between the two grading methods of nuclear opacity: Densitometry_pentacam and LOCS III classification (τ_b = 0.414, p = 0.000). We also found a positive correlation between ACD_pentacam and ACD_sono (r = 0.823, p = 0.000) and between ACD_pentacam and ACV (r = 0.650, p = 0.000). There were significant differences between the results of LT_pentacam and LT_sono. The final regression model identified Densitometry_pentacam, viscoelastics and Pupil_CCC as independent predictors of decreased postoperative corneal endothelial cell density (CD) at postoperative day 3, and Densitometry_pentacam, viscoelastics, and ACV as independent predictors of decreased CD two months postoperatively (p<0.05).

Conclusions

Good agreement was found between all results obtained with the Pentacam and conventional methods except LT. Analyzing anterior chamber parameters preoperatively using Pentacam could be helpful to predict postoperative endothelial cell loss.     

Reticular epithelial corneal edema as a novel side-effect of Rho Kinase Inhibitors: An Indian scenario

Purpose:To describe clinical course, characteristics, and outcome of reticular epithelial corneal edema (RECE) occurring as a not-so-infrequent adverse effect of a novel drug, Rho-kinase inhibitors (ROCK-I)- netarsudil (0.02%) and ripasudil (0.4%).Methods:This was a retrospective observational non-randomized study. In this study, 12 eyes of 11 patients presenting at a tertiary eye care center between April 2021 and September 2021 were included. All 12 eyes developed a distinctive honeycomb pattern of RECE after starting topical ROCK-I. All patients were subjected to detailed ophthalmic examinations.Results:Eight patients were started on netarsudil (0.02%) and three on ripasudil (0.4%). Five eyes had a prior history of corneal edema. The remaining seven had the presence of ocular comorbidities predisposing to corneal edema. The average time for RECE occurrence was 25 days for netarsudil and 82 days for ripasudil. Visual acuity decreased in two eyes, remained unaffected in four eyes, and could not be quantified in four eyes due to preexisting profound visual impairment. Five eyes had symptoms of ocular surface discomfort associated with bullae. Symptoms and bullae resolved in all eyes in whom ROCK-I was stopped. The average time to resolution of RECE was 10 days for netarsudil and 25 days for ripasudilConclusion:RECE after ROCK-I occurs with the use of both netarsudil and ripasudil, although the characteristics differ. The presence of corneal edema and endothelial decompensation seem to be a risk factor, and cautious use is warranted in these patients. Four clinical stages of RECE are described. ROCK-I act as a double-edged sword in patients with endothelial decompensation. Large-scale studies are required to know the exact incidence, pathophysiology, and long-term consequences of the aforementioned side-effect.     

多模态眼前段成像设备的研发及应用

目的:获取眼表图像的综合信息,建立眼表疾病综合诊断和评估.方法:将超高分辨率光学相干断层成像仪(ultra-high resolution optical coherence tomography,UHR-OCT)与基于裂隙灯生物显微镜的微血管成像系统相结合,开发了一种多模态、非接触式的眼科光学成像平台.结果:UHR-...     

眼前节成像与生物测量分析系统的最新进展

眼前节成像和生物测量分析系统广泛应用于眼前节疾病的诊断、白内障屈光手术的临床观察、眼前节结构生物参数的测量等.目前国内外许多仪器均能客观地对眼前节进行成像和生物测量,如裂隙灯生物显微镜、超声生物显微镜、光学相干断层扫描等.本次我们就各种最新的眼前节成像和生物测量仪器的原理、各自的特点及其在眼科领域的应用进行综述.