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1.
Alexander R. Edelmann Devang Patel Riley K. Allen Chad J. Gibson Al M. Best Sompop Bencharit 《The Journal of prosthetic dentistry》2019,121(3):404-410
Statement of problem
The design of porous tantalum trabecular metal–enhanced titanium (TM) dental implants promises improved osseointegration, especially when grafting materials such as demineralized bone matrix are used; however, studies are lacking.Purpose
The purpose of this retrospective study was to compare TM implants with conventional titanium alloy (Ti) implants with and without demineralized bone matrix in terms of peri-implant bone remodeling in the first year after implant loading.Material and methods
A chart review was used for all patients receiving Tapered Screw-Vent Ti and TM implants. Implants were placed and restored by a single provider between 2011 and 2015. Peri-implant bone remodeling was compared by using a paired t test (α=.05).Results
A total of 82 patients received 205 implants, 44 TM and 161 Ti implants (control). No implants failed in the TM group (survival rate of 100%), and 3 implants in total, 1 immediate, failed in the Ti groups (survival rate of 98.1%). TM implants exhibited a 0.28-mm bone gain on average, whereas the control group demonstrated 0.20 mm of marginal bone loss after the first year of implant loading. Multivariate logistic regression analysis demonstrated that the odds of having bone loss was 64% less (odds ratio: 0.36; 95% confidence interval: 0.14-0.94) in the TM group than in the Ti group after controlling for bone grafting, implant location, immediate placement, bone type, and pretreatment bone level.Conclusions
TM implants exhibited less peri-implant bone loss than the control Ti implants. 相似文献2.
Paulo Valdeci Worm Guilherme Finger Tobias Ludwig do Nascimento Carla Bittencourt Rynkowski Marcus Vinicius Martins Collares 《Journal of cranio-maxillo-facial surgery》2019,47(5):715-719
Objective
To evaluate the quality of life in patients with moderate or large cranial bone defects before and after late cranioplasty.Methods
Authors performed a prospective clinical trial including all consecutive patients that filled inclusion criteria during a period of 1 year. All patients answered the quality of life SF-36 questionnaire in 5 different times. Besides authors gathered information about the primary trauma and demographic characteristics.Results
A total of 70 consecutive patients were admitted to the hospital during the study period, and 62 were included in the project. Cranioplasty statistically improved patients' quality of life in all 8 domains after a 24 months follow-up.Conclusion
Cranioplasty has a significant impact over the quality of life in brain trauma victims who survived the primary trauma and harbor a large cranial bone defect. 相似文献3.
Kyoko Baba Yasuharu Yamazaki Yumiko Sone Yoshika Sugimoto Kazuno Moriyama Takayuki Sugimoto Kennichi Kumazawa Yasuhito Shimakura Akira Takeda 《Journal of cranio-maxillo-facial surgery》2019,47(4):668-675
Purpose
Umbilical cord blood-derived platelet-rich plasma (UCB-PRP) containing growth factors has attracted attention as a biomaterial useful for regenerative medicine. The osteoblastic differentiation of umbilical cord-derived mesenchymal stromal cells (UC-MSCs) can be induced by UCB-PRP.Materials and methods
Nine samples of UC and UCB were used to conduct an in vitro study that determined the contents of three growth factors (i.e., platelet-derived growth factor, transforming growth factor β-1, and vascular endothelial growth factor) and that examined, by staining with Alizarin red, their ability to induce the osteoblastic differentiation of UC-MSCs at the baseline, 3 months, and 3 years of cryopreservation.Results
The contents of growth factors in cryopreserved UCB-PRP were markedly elevated compared to those found in UCB at baseline. The samples of UCB that were added with cryopreserved UCB-PRP and those with bone morphogenetic protein-2 were stained granularly with Alizarin red, thus indicating the presence of calcium. The samples of UCB that were not added with UCB-PRP were not stained with Alizarin red. The above-mentioned contents and ability were maintained at 3 years of cryopreservation. Cryopreserved UCB-PRP possibly and advantageously induced the osteoblastic differentiation of UC-MSCs.Conclusion
The potential clinical application of cryopreserved UCB-PRP to regenerative medicine was suggested. 相似文献4.
Yosuke Tanaka Soichiro Sonoda Haruyoshi Yamaza Sara Murata Kento Nishida Yukari Kyumoto-Nakamura Norihisa Uehara Kazuaki Nonaka Toshio Kukita Takayoshi Yamaza 《Journal of endodontics》2019,45(5):591-598.e6
Introduction
Stem cells isolated from the root apical papilla of human teeth (stem cells from the apical papilla [SCAPs]) are capable of forming tooth root dentin and are a feasible source for bioengineered tooth root regeneration. In this study, we examined the effect of acetylsalicylic acid (ASA) on odontogenic differentiation of SCAPs in vitro and in vivo.Methods
SCAPs were cultured under odontogenic conditions supplemented with or without ASA. ASA-treated SCAPs were also subcutaneously transplanted into immunocompromised mice.Results
ASA accelerates in vitro and in vivo odontogenic differentiation of SCAPs associated with down-regulation of runt-related nuclear factor 2 and up-regulation of specificity protein 7, nuclear factor I C, and dentin phosphoprotein. ASA up-regulated the phosphorylation of AKT in the odontogenic SCAPs. Of interest, pretreatments with phosphoinositide 3-kinase inhibitor LY294402 and small interfering RNA for AKT promoted ASA-induced in vitro and in vivo odontogenic differentiation of SCAPs. LY294402 and small interfering RNA for AKT also suppressed the ASA-induced expression of runt-related nuclear factor 2 and enhanced ASA-induced expression of specificity protein 7, nuclear factor I C, and dentin phosphoprotein in SCAPs.Conclusions
These findings suggest that a combination of ASA treatment and suppressive regulation of the phosphoinositide 3-kinase–AKT signaling pathway is a novel approach for SCAP-based tooth root regeneration. 相似文献5.
Nynke Lie Hans-Albert Merten Kensuke Yamauchi Jörg Wiltfang Peter Kessler 《Journal of cranio-maxillo-facial surgery》2019,47(3):454-460
Introduction
In edentulous patients the form and size of the maxillary sinus vary greatly. Therefore sinus floor augmentation is a standard procedure for implantological purposes. As the sinus membrane cannot be characterized as periosteum, various augmentation materials are used.Hypothesis
an artificially generated space underneath the sinus membrane in the floor of the sinus will lead to spontaneous callus forming and a stable bony consolidation without augmentation material.Methods
Ten edentulous patients with highly atrophic maxillae were selected. Augmentation of the sinus floor was carried out in a split-mouth study design: On one side a combination of autogenous and xenogenous bone was used, and on the contralateral side a sinus membrane elevation was performed without using any substitutes. After a 6-month interval bone specimens from the test regions were harvested during implant placement.Results
Clear histological evidence of new bone formation was found in all human bone specimens. An active de-novo bone formation process could be proven by the presence of Haversian systems (osteons) displaying osteoblastic and osteoclastic activity.Conclusion
In the maxillary sinus of edentulous patients a spontaneous callus-derived de-novo bone formation is possible by elevating the sinus membrane without using augmentation materials. 相似文献6.
Statement of problem
An assessment of the evidence for the antagonist enamel wear of tooth-supported monolithic zirconia posterior crowns is lacking.Purpose
The purpose of this systematic review was to identify and summarize clinical studies related to the antagonist enamel wear of tooth-supported monolithic zirconia posterior crowns.Material and methods
PubMed, Embase, and Cochrane library searches were performed and complemented by manual searches from database inception to December 25, 2017, for title and abstract analysis.Results
Initially, 198 articles were obtained through database searches. Twenty-one articles were selected for full-text analysis, and 5 studies met the inclusion criteria. Because of the heterogeneity in design, surface treatment, measurement methods, and wear parameters, a meta-analysis was not possible. The selected studies were analyzed regarding the antagonist natural enamel wear of zirconia, measurement methods, and surface treatment. The results of the antagonist enamel wear varied widely, which made comparing them scientifically with absolute values difficult.Conclusions
This review indicated that the antagonist enamel wear of zirconia was similar to or more than that of natural teeth but less than that of metal-ceramics. Additional properly designed, longer follow-up clinical trials with larger sample sizes are needed to evaluate the antagonist enamel wear of monolithic zirconia crowns in vivo. 相似文献7.
Shajidan Kelimu Mariko Hattori Shataer Awuti Mahmoud E. Elbashti Yuka I. Sumita Hisashi Taniguchi 《The Journal of prosthetic dentistry》2019,121(4):671-675
Statement of problem
A palatogram aids prosthodontists and speech pathologists in evaluating the precise prosthetic treatment needed and the effectiveness of such treatment to improve speech intelligibility. Powder is commonly used to visualize tongue-palate contact, where wetted areas of powder in the oral cavity reveal such contact during palatography. However, discomfort and the risk of aspiration are among the shortcomings of this method, and an improved method is needed.Purpose
The purpose of this in vitro study was to examine the feasibility of a new method of palatography that uses airborne-particle–abraded acrylic resin so that wet areas can be easily distinguished from dry areas.Material and methods
Seventy-two specimens of heat-polymerized acrylic resin were prepared in 6 different resin colors. After the specimens had been airborne-particle abraded, CIELab color values for each specimen were measured using a colorimeter under dry and wet conditions and recorded. Color difference (ΔE) was then computed, and a paired Student t test, 1-way analysis of variance, and multiple comparison using the Tukey post hoc analysis were applied (α=.05).Results
A significant color difference was found between the 2 conditions in all acrylic resin specimens examined. Mean ΔE ranged from 5.58 to 6.76.Conclusions
The results indicated that an airborne-particle–abraded acrylic resin surface can show color differences made by wetting on palatograms. 相似文献8.
Priscilla Medina-Sotomayor Agustín Pascual-Moscardo Isabel Camps A 《The Journal of prosthetic dentistry》2019,121(5):811-820
Statement of problem
The accuracy of digital scanners is acceptable for scanning a complete dental arch. However, whether that accuracy is sufficient for only 1 tooth within the dental scan of a complete dental arch is unclear.Purpose
The purpose of this in vitro study was to evaluate and compare the accuracy of 4 intraoral scanners on a complete dental arch and on prepared teeth digitally isolated from the digital scan in terms of trueness and precision.Material and methods
A model of a complete dental arch with tooth preparations was scanned 40 times with each of the 4 digital scanners. Their accuracy was evaluated by using 3-dimensional (3D) software to compare the test models with a highly accurate reference model. The data were digitally processed to isolate the prepared teeth and evaluate them in the same way. The data were statistically analyzed using the Levene test and the Tamhane's T2 test (α=.05).Results
In scans of a complete dental arch, the True Definition scanner had the best accuracy values, followed by TRIOS, iTero, and Omnicam. For prepared teeth isolated from the dental arch, both True Definition and TRIOS had the best values, followed by iTero and Omnicam.Conclusions
In both long-span scans of the complete dental arch and isolated prepared teeth, the True Definition scanner had the greatest accuracy, closely followed by TRIOS. 相似文献9.
Seung-Won Yang Jong-Eun Kim Yooseok Shin June-Sung Shim Jee-Hwan Kim 《The Journal of prosthetic dentistry》2019,121(3):417-425
Statement of problem
Zirconia is a widely used restorative material. However, phase transformation on clinical application of zirconia has not yet been studied.Purpose
The purpose of this study was to evaluate the wear, surface roughness, and aging associated with polished translucent zirconia in both in vitro and clinical experiments.Material and methods
In vitro experiments were performed with Rainbow and Katana zirconia blocks and natural tooth enamel as the control. They were subjected to 100 000 loading cycles with a maxillary premolar antagonist. All specimens were analyzed for wear, and the zirconia specimens were evaluated for surface roughness and monoclinic phase (m-phase) transformation by X-ray diffractometry before and after cyclic loading. The clinical study included participants who required single-crown implant-supported restorations replacing the first or second molar. The participants received Rainbow or Katana zirconia prostheses (n=15, each). For wear analysis, impressions of each prosthesis, antagonist, and adjacent tooth were made at 1 week and 6 months after crown delivery. The occlusal relationship of the crowns in maximum intercuspation was evaluated by using the T-Scan 8 occlusal diagnostic system. The degree of transformation of zirconia to the m-phase was measured by using X-ray diffractometry of the crowns after 6 months of use.Results
Zirconia induced significantly greater enamel wear than the natural tooth control. Katana specimens exhibited significantly greater wear and surface roughness than the Rainbow specimens. The degrees of antagonistic wear and zirconia phase transformation in the clinical experiment were significantly greater than those in the in vitro experiment. The Katana groups showed significantly higher m-phase levels than the Rainbow groups.Conclusions
Phase transformation of zirconia occurs within 6 months of clinical use, and the wear and degrees of phase transformation varied according to the zirconia product used. 相似文献10.
Björn Gjelvold Deyar Jallal Hadi Mahmood Ann Wennerberg 《The Journal of prosthetic dentistry》2019,121(3):498-503
Statement of problem
Different factors influence the degree of deviation in dental implant position after computed tomography–guided surgery. The surgical guide–manufacturing process with desktop 3D printers is such a factor, but its accuracy has not been fully evaluated.Purpose
The purpose of this in vitro study was to evaluate the deviation in final dental implant position after the use of surgical guides fabricated from 2 different desktop 3D printers using a digital workflow.Material and methods
Twenty 3D-printed resin models were prepared with missing maxillary premolar. After preoperative planning, 10 surgical guides were produced with a stereolithography printer and 10 with a digital light-processing (DLP) printer. A guided surgery was performed; 20 dental implants (3.8×12 mm) were installed, and a digital scan of the dental implants was made. Deviations between the planned and final position of the dental implants were evaluated for both the groups.Results
A statistically significant difference between stereolithography and DLP were found for deviation at entry point (P=.023) and the vertical implant position (P=.009). Overall lower deviations were found for the guides from the DLP printer, with the exception of deviation in horizontal implant position.Conclusions
The tested desktop 3D printers were able to produce surgical guides with similar deviations with regard to the final dental implant position, but the DLP printer proved more accurate concerning deviations at entry point and vertical implant position. 相似文献11.
Ankur Dahiya Nadim Z. Baba Mathew T. Kattadiyil Charles J. Goodacre Akshita Mann 《The Journal of prosthetic dentistry》2019,121(3):504-509
Statement of problem
Excess cement around dental implants is a significant cause of peri-implant inflammation. Research has focused on approaches to cement removal, the type of cement used, and the different instruments used for cement removal with titanium abutments. However, data comparing zirconia with titanium abutments are lacking.Purpose
The purpose of this in vitro study was to compare the effectiveness of excess cement removal from zirconia and titanium custom abutments using an explorer and to compare the effects of cement removal on the abutment surfaces.Material and methods
Implant analogs were placed in a cast in the position of the 2 maxillary central incisors. After creating similar emergence profiles for both the implant abutments, 18 zirconia and titanium custom abutments were fabricated with 1-mm subgingival finish lines on the facial and interproximal areas and an equigingival finish line on the palatal side. The crowns were cemented with zinc oxide-eugenol cement, and a steel explorer was used to remove the excess cement. All abutments were analyzed under a scanning electron microscope for cement remnants and scratches.Results
The mean surface area of cement remnants on the zirconia abutments was 778 ±113 μm2, and for titanium abutments, it was 1123 ±252 μm2, which in terms of the mean percentage area was 3.27% of the total surface area of zirconia and 4.71% of titanium abutments. Only a few abutments from each group showed scratches, and no deep scratches or gouges were observed.Conclusions
Zirconia and titanium abutments had statistically similar cement remnants. Scratches were observed on only a few specimens. 相似文献12.
Oral Cenk Aktas Wolfgang Metzger Ayman Haidar Yahya Açil Aydin Gülses Jörg Wiltfang Catharina Marques Sacramento Frank Philipp Nothdurft 《Journal of cranio-maxillo-facial surgery》2019,47(4):661-667
Background
Promoting the directional attachment of gingiva to the dental implant leads to the formation of tight connective tissue which acts as a seal against the penetration of oral bacteria. Such a directional growth is mostly governed by the surface texture.Material and methods
In this study, three different methods, mechanical structuring, chemical etching and laser treatment, have been explored for their applicability in promoting cellular attachment and alignment of human primary gingival fibroblasts (HGFIBs).Results
The effectiveness of mechanical structuring was shown as a simple and a cost-effective method to create patterns to align HGIFIBs.Conclusion
Combining mechanical structuring with chemical etching enhanced both cellular attachment and the cellular alignment. 相似文献13.
Lisa A. Lang Sarah E. Hansen Norma Olvera Sorin Teich 《The Journal of prosthetic dentistry》2019,121(4):611-617
Statement of problem
Identifying factors that affect the clinical outcomes of implant therapy is important.Purpose
The purpose of this retrospective study was to determine whether implant location was a factor affecting the complication and failure rates of single-tooth implant-supported restorations in a predoctoral setting.Material and methods
The charts of 431 patients treated with a surgically placed dental implant and restored with a single crown in the predoctoral clinic were analyzed. Data on implant location, type of complication (surgical or prosthetic), and type of failure were collected and analyzed according to implant location using the Fisher Exact Test and Mantel-Haenszel Exact Chi Square Test analysis (α=.05).Results
The charts revealed 158 complications (68 surgical and 90 prosthetic) in 110 patients, and 3.9% of the implants failed. No statistically significant difference was found between the number of surgical complications or prosthetic complications in the maxilla and the mandible (P=.469).Conclusions
Jaw location (maxilla compared with mandible) of the implant had no statistically significant impact on the incidence of surgically or prosthetically related complications. No statistically significant difference was found in overall implant failures, surgical failures, and prosthetic failures between maxillary and mandibular implants. 相似文献14.
15.
Bruna M. Vetromilla Lucas P. Brondani Tatiana Pereira-Cenci César D. Bergoli 《The Journal of prosthetic dentistry》2019,121(3):398-403.e3
Statement of problem
A consensus regarding which implant-abutment connection type would perform best in the anterior maxilla is lacking.Purpose
The purpose of this systematic review was to determine the best implant-abutment connection type for anterior single-tooth implants considering esthetics, success, and survival rates.Material and methods
An electronic search was conducted in MEDLINE, Scopus, Embase, and the Cochrane Library databases to identify clinical studies on single-tooth implants with external and internal hexagon, and/or Morse taper connections. These studies needed to describe at least one of the following outcomes: esthetic score, survival/success rate, or marginal bone loss. The included studies and reports were assessed for bias using the Cochrane risk of bias tool.Results
Of the 891 articles identified, 29 were selected and analyzed. The most common technical complications were abutment screw loosening and crown-cement loosening, while dehiscence and recession were the most common biological complications. The most frequent complications were dehiscence for external hexagon, crown-cement loosening for the internal hexagon, and ceramic fracture for the Morse taper. Esthetics were favorable for all connections, but the internal hexagon performed better. However, better results for marginal bone loss, success, and survival were found for the Morse taper. The global annual failure rate was 0.90% and 0.2% for Morse taper, 0.3% for external hexagon, and 2.2% for internal hexagon.Conclusions
This review suggests that Morse taper performs better for survival, success, and marginal bone loss. Internal hexagon performed better for esthetic parameters. Additional controlled studies are needed to provide stronger evidence because the evidence generated in this study was considered low. 相似文献16.
Panagiotis Dragonas Julie H. Schiavo Gustavo Avila-Ortiz Archontia Palaiologou Theodoros Katsaros 《Journal of cranio-maxillo-facial surgery》2019,47(3):443-453
Purpose
This systematic review aimed at assessing the effects of PRGF in new bone formation, soft tissue healing and post-operative pain and swelling in sites that underwent ridge preservation, ridge augmentation and maxillary sinus augmentation procedures.Materials and methods
A comprehensive literature search employing seven databases was conducted by two independent reviewers. Only randomized and non-randomized controlled clinical trials using PRGF alone or in combination with bone grafting materials were selected.Results
Overall, 919 studies were identified, of which a total of 8 articles were included in the qualitative analysis. Two of the selected studies reported on ridge preservation, one on ridge augmentation and five on maxillary sinus augmentation. Positive results were recorded for soft tissue healing and post-operative pain and swelling following these procedures. However, outcomes of PRGF on new bone formation post extraction and on maxillary sinus augmentation when combined with other biomaterials were conflicting. Meta-analysis could not be conducted for any variables due to the heterogeneity of selected studies.Conclusion
Limited evidence exists on the effects of PRGF in different intraoral bone grafting procedures, with some benefit reported on soft tissue healing and post-operative symptomatology. As this platelet concentrate is commonly used in clinical practice, further research is needed to fully assess its clinical indications and effectiveness. 相似文献17.
Fatih Karayürek Ela Tules Kadiroğlu Yusuf Nergiz Neslihan Coşkun Akçay Selçuk Tunik Berna Ersöz Kanay Ersin Uysal 《Journal of cranio-maxillo-facial surgery》2019,47(5):815-825
Aim
The current study was based on the hypothesis that the use of PRF with bone graft materials might increase bone regeneration and focus on the histopathological and immunohistochemical aspects following application of PRF with autogenous graft, xenograft and B-TCP in a rabbit model.Material and methods
This study was performed on the twenty-eight male New Zealand divided into four group. Two defects with a diameter 10 mm were opened in calvarium. After PRF preparation, right defects were evaluated as empty defect or graft group, and left defects were evaluated as PRF test group. All animals were sacrificed at the end of 8 weeks and specimens were examined histopathologically and immunohistochemically.Results
The most superior histopathological results were obtained in the autograft group. The combination of β-TCP-PRF could not provide superiority over the β-TCP group. The immunohistochemical results showed that, in the PRF/BTCP group, the expression of osteopontin and osteonectin was relatively higher compared to the only-BTCP group.Conclusion
In terms of new bone formation, autograft combined with PRF yielded superior results but the combination of β-TCP-PRF had no effect compared to the only-BTCP group. However, further experimental and clinical studies might be beneficial to clarify the exact mechanism and results of combining PRF with bone grafts on bone healing process. 相似文献18.
Carlo Maiorana Pier Paolo Poli Anna Mascellaro Susanna Ferrario Mario Beretta 《Journal of cranio-maxillo-facial surgery》2019,47(5):805-814
Purpose
To evaluate the long-term outcome of dental implants placed with a staged procedure in resorbed alveolar ridges reconstructed with iliac crest autogenous onlay grafts.Materials and methods
All consecutive patients treated with iliac crest onlay bone grafts and dental implants were retrospectively evaluated. During the appointment, clinical and radiological examinations were conducted to assess implant survival. A survived implant was defined as an implant still stable and in function at the follow-up visit. Implant survival was estimated at the implant level using Kaplan-Meier analyses. The cumulative survival rate was estimated using a life-table analysis. Subgroup analyses were performed for age, position, and type of retention using the log-rank test. A p-value of <0.05 was considered statistically significant.Results
The cohort consisted of 21 female subjects receiving a total of 140 rough-surface titanium implants. Of them, 128 survived and 12 failed, yielding a cumulative survival rate of 91.1% over a median survival time of 312 months. Implants supporting cement-retained prostheses exhibithed lower survival rate compared to screw-retained restorations (p = 0.001).Conclusion
Implants placed in bone augmented with iliac crest onlay grafts showed high long-term survival rates. Cement-retained restorations were more prone to develop implant failures. 相似文献19.
Mohammed Nadeem Ahmed Bijle Manikandan Ekambaram Edward C.M. Lo Cynthia Kar Yung Yiu 《Journal of Evidence》2019,19(1):28-33
Background
Several significant issues on clinical trials reporting the effect of arginine-containing dental products have been addressed in systematic reviews and meta-analyses identifying the need for high-quality randomized clinical trials. A further methodological analysis of the given systematic reviews with meta-analysis on arginine products might provide information for future high-quality randomized clinical trials and current clinical practice.Objective(s)
The objective was to perform a meta-epidemiological assessment of meta-analyses reporting the anticaries effect of arginine-containing formulations.Methods
The data on risk-of-bias assessment, effect size measure, dispersion of estimated precision, and follow-up period were summarized for the meta-epidemiological review analysis.Results
Studies with larger magnitude of effect sizes might present with unclear random sequence generation and unclear allocation concealment representing the selection bias. There was a significant strong negative correlation between the follow-up time and dispersion of precision estimates (rs = ?0.79, P = .034).Conclusion
Results show that clinical trials on arginine dental products have methodological shortcomings. Both the selection bias and follow-up period influence the effect size magnitude and subsequent precision dispersion during evidence synthesis in clinical trials on arginine-containing dental products. 相似文献20.
Sunil Kim So-Young Park Yoon Lee Chan-Joo Lee Bekir Karabucak Hyeon-Cheol Kim Euiseong Kim 《Journal of endodontics》2019,45(4):442-446