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多重用药可增加老年人药物不良反应及不良事件的风险,处方精简是在医护人员监督下,结合患者医疗状况、当前的功能和个人偏好,权衡药物使用利弊,在保证疗效的同时减少或停用药物的系统过程。处方精简可减少患者跌倒、缩短住院时长、降低再入院率。本文对处方精简进行简要概述,并介绍目前可使用的处方精简辅助工具。 相似文献
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老年人作为一个特殊群体,其各脏器功能减退,多病共存,同时不可避免地存在多重用药的问题.多药联合治疗可能增加药物相互作用的机会,不良的药物-药物相互作用(ADI)严重影响老人健康,甚至可造成残疾和死亡.我们在此报告3个典型的ADI病例以提高大家对由多重用药引起的不良药物相互作用的认识. 相似文献
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<正>多重用药通常是指患者接受药物治疗时使用了潜在的不适当药物或者同时服用了6种及以上的药物〔1〕。用药种类越多,药物不良反应(ADRs)的发生率越高。研究显示,多重用药在老年人住院原因中占第3位,在医院获得性疾病中列居第一位〔2〕。医护人员作为老年多重用药的管理主体,对多重用药的认知管理直接影响老年人的用药安全。本文就老年患者多重用药的认知管理进展进行综述。1老年人多重用药现状 相似文献
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近年来,老年人中心血管病的发病率日益增高,因此,应用心血管病的药物也较多,为了正确合理选用这些药物,本重点阐述老年人对药物作用的生理特性和心血管病药物临床应用注意的问题。 相似文献
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殷召玲 《糖尿病天地(学术刊)》2021,(12):83-85
目的:统计并分析西药处方的不合理用药情况,制定具体的西药处方管理对策.方法:随机选择枣庄市薛城区中医院在2020年10月至2021年10月期间处方3000张,分析处方的用药情况.结果:不合理用药情况主要包括:选择缺少合理性、药物的用法与用量缺少合理性、药物配伍不合理、用药次数不合理、用药间隔时间不合理、药品主流名称不统... 相似文献
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<正> 单纯收缩期高血压(ISH)是老年人最常见的高血压类型之一。SHEP、Syst Europe、Syst China等大规模临床试验表明,收缩压是较舒张压更为重要的心脑血管危险因素,老年ISH患者的预后较双期高血压和单纯舒张期高血压患者的预后差。老年 相似文献
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药物性肝损伤(drug-induced liver injury,DILI)是发达国家急性肝功能衰竭的首要病因,也是食品和药物管理局(food and drug administration,FDA)对药物采取警示的最常见的原因.重视DILI的基础和临床研究是当前刻不容缓的任务. 相似文献
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Hitoshi Komiya Hiroyuki Umegaki Atsushi Asai Shigeru Kanda Keiko Maeda Takuya Shimojima Hideki Nomura Masafumi Kuzuya 《Geriatrics & Gerontology International》2018,18(1):33-41
Aim
Polypharmacy, which is often observed in elderly patients, has been associated with several unfavorable outcomes, including an increased risk of potentially inappropriate medications, medication non‐adherence, drug duplication, drug–drug interactions, higher healthcare costs and adverse drug reactions. A significant association between polypharmacy and adverse outcomes among older people living in the community has also been confirmed. A reduction in the number of medications should thus be pursued for many older individuals. Nevertheless, the factors associated with polypharmacy in elderly home‐care patients have not been reported. Here, we investigated those factors in elderly home‐care patients in Japan.Methods
We used the data of the participants in the Observational Study of Nagoya Elderly with Home Medical investigation. Polypharmacy was defined as the current use of six or more different medications. We carried out univariate and multivariate logistic regression analyses to assess the associations between polypharmacy and each of several factors.Results
A total of 153 home‐care patients were registered. The mean number of medications used per patient was 5.9, and 51.5% of the patients belonged to the polypharmacy group. The multivariate model showed that the patients’ scores on the Charlson Comorbidity Index and the Mini‐Nutrition Assessment Short Form were inversely associated with polypharmacy, and potentially inappropriate medication was most strongly associated with polypharmacy (odds ratio 4.992).Conclusions
The present findings showed that polypharmacy was quite common among the elderly home‐care patients, and they suggest that home‐care physicians should prescribe fewer medications in accord with the deterioration of home‐care patients’ general condition. Geriatr Gerontol Int 2018; 18: 33–41 . 相似文献17.
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