毛母质瘤合并表皮囊肿1例

<正>1病历摘要患儿男，11岁。因项部皮下结节3个月，于2020年3月22日就诊于我科门诊。患儿3个月前发现项部深在性结节，无痛痒等自觉症状。否认发病前外伤史。既往史无特殊，家族中无类似疾病患者。体格检查：生命体征平稳，各系统检查均正常。皮肤科检查：项部可触及一直径约1.5 cm肤色皮下结节，边界清楚（图1），质硬，不易推动；左膝一3 cm×4 cm咖啡斑，全身未见其他包块及肿瘤。     

毛母质瘤40例临床病理分析

目的：探讨毛母质瘤的临床和病理特点。方法：对40例毛母质瘤进行了临床资料和组织病理回顾性分析。结果：男女发病比例为1：1，平均发病年龄21．2岁，平均病程2．3年，10岁以内发病者20％，20岁以内者加％，30～40岁35％，除1例多发外，均为单发的质地较硬的皮下结节，有压痛者7例（17．5％），病理上均可见到影细胞。发现3例特殊类型，1例表现为穿通型，其中2例为与表皮囊肿相关的毛母质瘤。临床正确诊断率15％。结论：毛母质瘤少见，临床表现多样，影细胞是确诊的重要依据和必要条件。病理上可以出现特殊类型。     

毛母质瘤

毛母质瘤临床表现多样,无特征性,极易误诊,但其组织病理学改变具有特征性。现报告1例。     

多发性毛母质瘤

报告1例多发性毛母质瘤。患者女,14岁,背部3个皮下结节伴触痛1年。3处皮损均切除并行组织病理检查:(背中部皮损)真皮内可见由嗜碱性粒细胞、影细胞、过渡细胞构成的肿瘤团块;(背上部、下部皮损)真皮内见影细胞、吞噬含铁血黄素的异物巨细胞及钙沉积。诊断:多发性毛母质瘤。     

毛母质瘤一例

正临床资料患者,男,24岁。主因颈后肿物2年余,于2015年3月6日就诊。2年前,患者颈后中部皮下出现一小指大肿物,无不适,缓慢生长,未诊治。既往体健;否认局部有外伤史;无此类疾病家族史。体格检查:各系统无异常。皮肤科情况:颈后中部可见一皮肤稍隆起区域,表皮正常,皮下可扪及一直径约3cm的深在结节,质地较硬,稍有弹性,可移动,无波动感,表面皮肤触觉、痛温觉正常。实验室检查:     

毛母质瘤1例

患者女．70岁。困左面颊出现紫红色结节伴瘙痒、破溃4个月余,于2006年3月27日来我中心门诊就诊。4个月前无明显诱冈患者左面颊部出现一绿豆大红色丘疹,无明显瘙痒及疼痛,曾自行使用细绳结扎皮损,结果皮损迅速增大至鸽蛋大,质地稍硬,自觉瘙痒不适,搔抓后皮损中心破溃、出血、结痂。发病前无外伤史．家族中无类似疾病患者。[第一段]     

毛母质瘤1例

1临床资料患者,女,43岁,左侧颧部淡黄色结节伴瘙痒半年,于2007年9月13日就诊。半年前无明显诱因左侧颧部出现一米粒大丘疹伴轻度瘙痒,未予治疗,后     

耳后毛母质瘤1例

患者男,51岁.左耳后淡红色结节半年于2009年5月15日就诊.患者半年前发现左耳后绿豆大皮下结节,渐进增大,且顶部出现囊性物,无瘙痒及疼痛等不适,皮损未溃破.发病前无虫咬、外伤史,无其他器官肿瘤病史,家族中未见类似疾病患者.     

水疱型毛母质瘤一例

正临床资料患儿,女,13岁。因右侧肩部结节5个月,出现水疱样外观1个月,于2015年7月29日就诊。5个月前,患儿右侧肩部出现一蚕豆大小淡红色质硬结节,缓慢增大;1个月前结节表面出现水疱样外观,无自觉症状。自起病以来,患儿无发热、肌无力、肌肉酸痛及肌肉萎缩等全身症状。患儿既往体键,无传染病及遗传病史,家族成员中无类似疾病患者。皮损局部无外伤史或蚊虫叮咬史。体格检查:一般情况可,     

传染性软疣伴发表皮囊肿1例

报告1例传染性软疣伴发表皮囊肿。患者男，71岁。鼻尖部出现一黄豆大红色丘疹4个月，无自觉症状。皮损组织病理检查显示真皮内见一囊肿，囊壁细胞内见嗜酸性圆形或椭圆形病毒包涵体，囊腔内的角质物网眼内亦见病毒包涵体。组织病理诊断为传染性软疣发表皮囊肿。     

Pilomatricoma with a Bullous Appearance

A 15-year-old Japanese girl had an asymptomatic nodule on the right thigh of seven months' duration. The clinical appearance was similar to that of a bulla. There was a history of blunt trauma from dog scratch to the skin over the tumor shortly before tumor growth. Histopathological findings were consistent with pilomatricoma. In the overlying dermis, the collagen bundles were compressed to the tissue surrounding the tumor and the large space was seen. Around the tumor, some dilated endothelium-lined vascular channels were found, which were identified as lymphatic vessels.     

Case of dystrophic calcinosis cutis in epidermal cyst arising from verrucous epidermal nevus

Dystrophic calcinosis cutis is diagnosed when calcium is deposited into previously damaged tissue by connective tissue disease, panniculitis, pseudoxanthoma elasticum or trauma. We report a case of dystrophic calcinosis cutis arising from the lesion of an epidermal cyst on the verrucous epidermal nevus. A 20‐year‐old woman presented with a polypoid pinkish tumor on a brownish, verrucous plaque. Histopathological findings of the pinkish tumor showed calcium deposits as amorphous, basophilic material lining the true epidermis in the upper dermis, which were compatible with dystrophic calcinosis cutis and the plaque was diagnosed as a verrucous epidermal nevus.     

Pilomatricoma associated with epidermoid cyst

The clinical and pathological features of 4 cases of pilomatricoma associated with epidermoid cysts, are described. None of the cases showed features of Gardner's syndrome.     

表皮囊肿1007例临床及病理分析

目的：分析表皮囊肿的临床及病理特点。方法：收集并分析2008年1月至2018年5月于无锡市人民医院确诊为表皮囊肿的1007例患者临床和病理资料。结果：1007例患者中男680例，女327例，平均年龄为(37.5±17.9)岁，21~50岁患者较其它年龄多发。皮损位于头面颈710例，发生破裂97例（13.7%）;躯干部179例，发生破裂23例（12.8%）;四肢96例，发生破裂9例（9.4%）。组织病理示伴慢性炎性改变者101例，肉芽肿性炎89例，伴钙化8例，伴黑素细胞痣3例。1007例患者中，临床诊断为表皮囊肿456例（45.3%），320例（31.8%）被误诊为皮脂腺囊肿。结论：表皮囊肿多发于青中年男性。头面及躯干部多见。表皮囊肿临床误诊率达54.7%，最易误诊为皮脂腺囊肿。     

Pilomatrical carcinosarcoma of the temple: A case report

Pilomatrical carcinosarcoma is a very rare entity, with only six cases reported until now. This report describes the case of a 100‐year‐old woman with a mass on the left temple that had existed for several decades but had recently grown in size. Histology showed an asymmetric lesion composed of basaloid cells, spindle cells, and “shadow” or “ghost” cells. Cells had atypical hyperchromatic nuclei with prominent nucleoli, high mitotic activity, and atypical mitosis. In the central area, an epidermal cyst‐like structure was seen. The diagnosis of pilomatrical carcinosarcoma was rendered. This case appeared to have arisen from malignant transformation of a pilomatricoma because of the long clinical history and existence of a benign epidermal cyst‐like structure. In addition, the observation that the basaloid cells and spindle cells showed a gradual transition from one to the other and that both types were positive for β‐catenin would seem to support a common clonal origin for the carcinomatous and sarcomatous components.