在线医疗平台中推荐热度的中介效应分析

目的 分析在线问诊中推荐热度对医生职称、医院等级的中介效应。方法 通过网络爬虫获取某在线医疗平台问诊数据,采用最优尺度回归,利用中介效应模型分析推荐热度的中介效应。结果 在问诊价格中,不论是否考虑医院科室,推荐热度对医生职称有部分中介效应,推荐热度的中介效应对总效应的贡献率为34.2%和35.6%,对医院等级具有遮掩效应。在线问诊量中,不考虑医院科室时,推荐热度对医生职称有完全中介效应;考虑医院科室时,推荐热度有部分中介作用,贡献率为54.1%;而医院等级对问诊量的影响完全被推荐热度替代。在满意度评价中,推荐热度完全替代了医生职称。结论 医生在医疗服务中努力提高自己的推荐热度,实现医生和患者两者的双赢。     

医学生图书馆焦虑现状研究

目的:了解医学生图书馆焦虑现状,为探索改善医学生图书馆焦虑的干预模式提供依据。方法:以小班为单位,整群随机抽取安徽医科大学二、三年级在校学生为研究对象,采用方差分析分析图书馆焦虑的危险因素。结果:到馆率低、对信息素质教育重要性的认识程度不够、信息能力差、接受图书馆利用教育晚和信息环境条件差是图书馆焦虑的危险因素。结论:图书馆应丰富馆藏信息资源,提供全方位的服务。学校应重视信息素质教育,使学生能充分、有效地利用图书馆的信息资源。     

Against medical ethics: a response to Cassell

This paper responds to Dr Cassell's request for a fuller explanation of my argument in the paper, Against medical ethics: a philosopher's view. A distinction is made between two accounts of ethics in general, and the philosophical basis of health work ethics is briefly stated. The implications of applying this understanding of ethics to medical education are discussed.     

用VBA实现医学文献计量中的预处理技术

以中国期刊全文数据库为例,通过VBA简单编程,在Excel文件中对网页检索数据进行行列转换,拆分并提取期刊论文作者、关键词及作者单位等数据,为医学文献计量统计分析做前期处理。     

Early response to medical treatment of trigeminal neuralgia in a Nigerian population

Background:

This study evaluates the clinical profile of patients suffering from trigeminal neuralgia (TN) and correlates the findings with early response of the patients to medical treatment.

Patients and Methods:

A 4-year prospective study in which patients diagnosed of TN were treated medically and followed up weekly for 8 weeks to determine early treatment outcome, in the University of Benin Teaching Hospital, Benin City, Nigeria.

Results:

Of the 287 patients seen during the study period, a total of 14 (4.9%) patients were diagnosed of TN. Thirteen (4.5%) of the cases were selected based on compliance to the 8-week follow-up visits, consisting of 8 (61.5%) males and 5 (38.5%) females, giving a ratio of 1.6:1. The mean age of the patients was 50±1.5 years. The mandibular (n = 6, 46.2%) and maxillary (n = 5, 38.5%) divisions of the trigeminal nerve were mostly affected. The lesion was slightly more common on the right side of the face (n = 7, 53.8%) than the left side (n = 6, 46.2%). Talking (n=4, 30.8%) and chewing (n = 3, 23.1%) were the most frequent trigger factors. The patients mostly described the pain as severe, spontaneous, and sharp (n = 5, 38.2%). Most patients became stable on tablets carbamazepine 200 mg 12 hourly, folic acid 5 mg daily, and phenytoin 100 mg daily. Good response was observed in most patients within 2 weeks (n = 6, 46.2%) of medical treatment, especially in patients at the seventh decade of age (n = 3, 23.1%) and those with lesions involving the mandibular division of the trigeminal nerve (n = 3, 23.1%).

Conclusion:

This study shows early response of TN to medical treatment. We recommend combination therapy of carbamazepine and folic acid in the treatment of patients, especially elderly patients with lesions involving the mandibular division of the trigeminal nerve.     

核因子E2相关因子作为结直肠癌化学预防治疗潜在靶点的研究进展

结直肠癌是消化系统的常见疾病,近30年来发病率一直呈升高趋势,其发病机制尚不完全清楚,许多研究表明结直肠癌的发生与遗传、饮食、炎症等因素相关。目前,一些针对结直肠癌的化学预防治疗药物在临床研究中展现出了令人惊喜的效果。已证实这些药物可激活核因子E2相关因子,后者促进启动子区域含有抗氧化应激反应元件的一系列二相解毒酶和抗氧化酶基因的表达,从而保护机体免受化学致癌剂的伤害,发挥肿瘤预防作用。本文将结合激活核因子E2相关因子功能与作用机制的报道,综述其在结直肠癌化学预防治疗中的最新研究进展。     

综合性医院内科门诊焦虑障碍患者生命质量研究

目的研究综合性医院内科门诊焦虑障碍患者的生命质量及其相关影响因素。方法对107例综合性医院内科门诊焦虑障碍患者进行汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)24项和SF-36健康调查量表评估;将焦虑障碍患者SF-36健康调查量表各维度评分与杭州市区居民生命质量常模进行比较;采用线性逐步回归法分析焦虑障碍患者生命质量的影响因素。结果除生理功能外,综合性医院内科门诊焦虑障碍患者SF-36健康调查量表各维度评分均明显低于常模(P<0.001)。焦虑障碍患者生命质量的受影响程度与HAMD、HAMA评分呈负相关(P<0.001和P<0.01),与病程呈正相关(P<0.05)。结论综合性医院内科门诊焦虑障碍患者的生命质量低于正常人,并受焦虑、抑郁症状和病程的影响。     

综合性医院内科门诊焦虑障碍患者生命质量研究

目的 研究综合性医院内科门诊焦虑障碍患者的生命质量及其相关影响因素。方法 对107例综合性医院内科门诊焦虑障碍患者进行汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）24项和SF-36健康调查量表评估;将焦虑障碍患者SF-36健康调查量表各维度评分与杭州市区居民生命质量常模进行比较;采用线性逐步回归法分析焦虑障碍患者生命质量的影响因素。结果 除生理功能外,综合性医院内科门诊焦虑障碍患者SF-36健康调查量表各维度评分均明显低于常模（P<0.001）。焦虑障碍患者生命质量的受影响程度与HAMD、HAMA评分呈负相关（P<0.001和P<0.01）,与病程呈正相关（P<0.05）。结论 综合性医院内科门诊焦虑障碍患者的生命质量低于正常人,并受焦虑、抑郁症状和病程的影响。     

昆明小鼠状态焦虑动物模型明暗箱实验的结构维度分析

目的 探讨明暗箱实验(Light-Dark Box,LDB)作为昆明小鼠状态焦虑动物模型的结构维度及测量有效性.方法 成年雄性昆明小鼠放入明暗箱,摄像系统记录5 min的行为变化,实验间隔1周进行2次;采用因子分析进行分析评价,实验参数如下:暗区潜伏期(Latence)、明区停留时间百分率(Ltime%)、明区水平运动...     

当代医学科技的发展对医学生的挑战

21世纪是知识和人才激烈竞争的时代,素质教育已形成共识,如何加强医学生素质教育,更好地适应社会对医学高级人才的需求,显得尤为迫切。医学生的成长有其自身的特点和规律,要适应现代化医疗科技的发展和要求,必须具备相应的科技素质。     

Reform in Australian medical schools: a collaborative approach to realising Indigenous health potential

The Australian medical education system is at a critical juncture in relation to what and how it delivers for Aboriginal and Torres Strait Islander health. Since 2004, three key organisations concerned with medical education have worked to provide a toolkit for implementation of sustainable reform within medical schools. The aim is a medical workforce trained in Indigenous health, and more Aboriginal and Torres Strait Islander doctors, leading to better health for Australia's Indigenous peoples.     

Imperatives in medical education and training in response to demands for a sustainable workforce

Factors to be considered in planning our medical workforce to meet future needs include: Need for outcomes-based curricular designs in medical schools and postgraduate training. Shortening the length of medical training. Improving career flexibility to permit professional re-invention. Developing awareness within the profession about how innovation happens.