Experience using nootropil in patients with chronic ischemic heart disease

Course nootropil treatment was conducted in 34 IHD patients with neurotic and neurotic-like diseases. Dynamic changes in the psychic state were assessed by the clinical scale and the MMPI psychological test. Significant improvement or normalization of the psychic state was achieved in 58.8 per cent of the patients treated with nootropil. The best results were obtained in the treatment of asthenic states. Administration of nootropil had no influence on the incidence of angina pectoris attacks and produced no side effects.     

Autonomic reactivity and intraoperative arterial hypertension in patients with ischemic heart disease

As patients with ischemic heart disease (IHD) may develop intraoperative hypertensive and hyperdynamic reactions provoking myocardial ischemia, the authors estimated reactivity of the autonomic nervous system before giving anesthesia. This was made for prediction of intraoperative hypertensive reactions and choice of an optimal anesthesia variant. Combination of spectral analysis of variability of the heart rhythm and active orthostatic test was employed for this purpose in 50 IHD patients undergoing myocardial revascularization.     

Treatment of erectile dysfunction in patients with essential hypertension and ischemic heart disease

AIM: To evaluate the effect of impasa on activity of N0-dependent processes in cardiological patients with erectile dysfunction (ED). MATERIAL AND METHODS: 58 patients with IHD and angina of effort and 48 patients with hypertension participated in the study of efficacy of conventional treatment combined with impasa on the course of the basic disease, peripheral blood count of desquamated endotheliocytes, microcirculation and erectile function. RESULTS: IHD patients given impasa showed increased exercise tolerance, less number of anginal attacks, improved coronary microcirculation, improved metabolism of vascular endothelium. Manifestations of erectile dysfunction regressed. Hypotensive therapy also reduced the above manifestations in hypertensive patients. CONCLUSION: The addition of impasa to conventional cardiotropic and hypotensive therapy promotes ED regression.     

Character peculiarities in patients with various forms of ischemic heart disease and hypertension

A total of 202 patients with coronary heart disease and 115 patients with hypertension were examined to study their specific and frustration characteristics. Isenk's questionnaire and Rosentsveig's test were used. In CHD and postinfarction cardiosclerosis extraversion prevailed, in hypertension intraversion was more common. The indicator of neuroticism was high among all the patients under study. The choleric temperament prevailed in angina pectoris. Choleric and melancholic peculiarities were typical of patients with postinfarction cardiosclerosis and hypertension. Extrapunitive reactions were clearly revealed by Rosenzweig's test in all the study groups.     

Diagnostic potentials of a precordial mapping method in patients with acute and chronic forms of ischemic heart disease

Diagnostic potentialities of modified 27 and 30 precordial ECG-leads were defined for rapid assessment of the coronary blood flow in patients with acute myocardial infarction (AMI) and chronic coronary heart disease during an acute pharmacological test. ECG criterita of limiting AMI size and ECG criteria of the ischemic reaction during the pharmacological xantinol nicotinate test were defined. It was proved that the use of multiple ECG leads raised the sensitivity of the ECG method in the diagnosis of AMI by 13.6% and in the diagnosis of stenosing atherosclerosis of the coronary arteries by 12.9%.     

Role of cardiovascular magnetic resonance in acute and chronic ischemic heart disease

Cardiovascular magnetic resonance (CMR) is a multi-parametric, multi-planar, non-invasive imaging technique, which allows accurate determination of biventricular function and precise myocardial tissue characterization in a one-stop-shop technique, free from the use of ionizing radiations. Though CMR has been increasingly applied over the last two decades in every-day clinical practice, its widest application has been in the assessment of ischemic cardiomyopathy.     

Characteristics of microcirculation and vascular responsiveness in elderly patients with hypertension and ischemic heart disease

Microcirculation and vascular responsiveness were studied in 52 patients with arterial hypertension and ischemic heart disease versus 48 healthy elderly persons. The patients were found to have defects of the end blood flow in all links of microcirculation, longer and more severe vasoconstriction of conjunctival and skin vessels in response to norepinephrine and cold stimulation tests.     

高血压患者血清微量元素的测定分析

目的　对高血压患者的血清微量元素进行分析,以期明确微量元素与高血压发生、发展的关系。方法　采用1:1配对病例对照研究方法,对6 9对高血压患者和对照者应用光谱仪扫描法测定了血清7种微量元素含量。结果　高血压组患者血清中钒(V)、铬(Cr)、铜(Cu)、锌(Zn)、钼(Mo)五种元素含量显著低于对照组(P <0 .0 5 ) ,锰(Mn)、钴(Co)元素含量两组间无差异。结论　血清微量元素与高血压存在密切关系,微量元素测定在高血压的预防、诊断、治疗中可以发挥重要作用。     

Comparative effectiveness of psychotropic drugs in patients with chronic ischemic heart disease]

As many as 348 courses of psychotropic and antianginal chemotherapy were performed for coronary disease confirmed angiographically. Hypochondriac patients were resistant to the drugs, depressive states and anxiety showed the best response. Tranquilizers and neuroleptic agents proved effective in anxiety, neuroleptics in cardiophobia and hypochondria, antidepressants in depression and asthenia. The addition of psychotropic drugs to antianginal therapy produced a positive effect on cardiac pain with antidepressants benefit ranking first, neuroleptics second and tranquilizers third. Being moderate and transient, treatment-related side effects did not cause the treatment discontinuation.     

Use of morphine analgesia in patients with acute forms of ischemic heart disease

The adequacy of morphine analgesia was studied in 77 patients with acute forms of coronary heart disease (CHD). The studies demonstrated that morphine analgesia was inadequate in 37.7% of the patients with acute CHD. Inadequate morphine analgesia was more frequently observed in patients with lower acute myocardial infarction, in those with severe or very severe pain requiring additional morphine administration, in those with bradycardia and hypotension or high arterial hypertension, in elderly patients after morphine readministration. The above categories of patients require more adequate analgesic methods.