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1.
Two new resin glycosides, batataosides I (1) and II (2), and five known compounds, friedelin (3), scopoletin (4), octadecyl caffeate (5), beta-sistosterol (6) and daucosterol (7), were isolated from the roots of Ipomoea batatas. Their structures have been determined based on the chemical and spectral data. Batataosides I and II have novel structures because the core simonic acid B was esterised with cinnamic acid for the first time, and three different substituent esterification groups in one resin glycoside is scarce. The absolute configuration of the aglycone was elucidated to be S by Mosher's method. 相似文献
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目的建立测定甘薯中咖啡酸及芦丁2组分含量的高效液相色谱法。方法色谱柱为Kromasil—C18柱(4.6mm×250mm,5μm),以乙腈1%醋酸水溶液为流动相进行梯度洗脱,检测波长为345nm,流速为1mL·min^-1。结果在选定的色谱条件下,咖啡酸和芦丁的含量分别为0.02603%和0.2022%。结论本法简单易行,可用于甘薯中咖啡酸及芦丁的含量测定。 相似文献
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Masateru Ono Hitoshi Fukuda Hiroko Murata Kazumoto Miyahara 《Journal of natural medicines》2009,63(2):176-180
Alkaline hydrolysis of the ether-soluble resin glycoside (jalapin) fraction of the leaves and stems of Ipomoea digitata L. (Convolvulaceae) gave six organic acids, isobutyric, (S)-2-methylbutyric, tiglic, n-decanoic, n-dodecanoic, and cinnamic acids, and two glycosidic acids, quamoclinic acid A and operculinic acid A. Further, a new genuine
resin glycoside, named digitatajalapin I, was isolated from the jalapin fraction, along with three known resin glycosides.
Their structures have been determined on the basis of chemical and spectroscopic data. 相似文献
5.
目的:研究用D101大孔吸附树脂富集仙茅中苯甲酸酯类酚苷的纯化工艺。方法:以仙茅苷乙和仙茅苷的吸附量和解吸附率为指标,考察了D101大孔吸附树脂对仙茅中苯甲酸酯类酚苷的静态和动态吸附及解吸附性能。结果:D101大孔吸附树脂富集仙茅中苯甲酸酯类酚苷的最佳工艺条件如下:吸附时间为8h,药液pH值为6,洗脱溶剂pH值为8,上样吸附和洗脱均在室温下进行,药液中苯甲酸酯类酚苷浓度为0.22mg/ml为最佳上样浓度,吸附流速为2.5Bv/h,洗脱溶剂为30%乙醇,洗脱剂用量为12Bv,二次纯化样品中苯甲酸酯类酚苷浓度为0.17mg/ml。结论:本纯化工艺简单、稳定,能将仙茅中仙茅苷和仙茅苷乙的总含量从0.022%的平均含量提高到1.60%,经二次纯化含量能达到5.08%。 相似文献
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Two new abietane diterpene glycosides, wilfordosides A (1) and B (2), were isolated from the roots of Tripterygium wilfordii. The structures of compounds 1 and 2 were established using spectroscopic methods including extensive 1D and 2D NMR analysis, in combination with chemical reactions. 相似文献
7.
Qiang Fu Shu-Bin Wang Shao-Hua Zhao Xiao-Juan Chen 《Journal of Asian natural products research》2013,15(7):697-702
Three new monoterpene glycosides, 2′-O-benzoylpaeoniflorin, albiflorin R2, and albiflorin R3 (1–3) were isolated from the roots of Paeonia lactiflora. Their structures were elucidated on the basis of spectroscopic means including one- and two-dimensional NMR experiments. 相似文献
8.
From the roots ofPatrinia scabiosaefolia (Valerianaceae), scopoletin (1), esculetin (2), oleanonic acid (3), 3-O-α-l-rhamnopyranosyl(1→2)-α-l-arabinopyranosyl oleanolic acid (4) and 3-O-α-l-rhamnopyranosyl (1→2)-α-l-arabinopyranosyl hederagenin (5) were isolated and characterized by spectral data. 相似文献
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目的:筛选优化白首乌中C21甾体酯苷类成分的提取工艺及大孔树脂纯化工艺。方法:采用正交试验设计,以C21甾苷得率为指标,优化乙醇回流提取工艺;比较AB-8及HP-20型大孔树脂的吸附效果,并以纯化后C21甾苷收率及浸膏中甾苷的质量分数为指标,优选纯化工艺。结果:C21甾苷的最佳提取工艺为:6倍量90%乙醇提取3次,每次1h。AB-8型大孔树脂对C21甾苷有较好的吸附分离性能,优选的纯化工艺为:上样液质量浓度1g.mL-1,以6倍量80%乙醇洗脱,纯化后总甾苷含量可达46.91%。结论:优选工艺简单稳定,对C21甾苷提取精制效果好,可为其工业制备提供参考依据。 相似文献
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Jun-Mian Tian Hong-Ping He Ying-Tong Di Xian-Wen Yang Zhu-Lin Gao Xiao-Jiang Hao 《Journal of Asian natural products research》2008,10(3):228-232
Three new lignan glycosides, mananthosides I-K (1-3), were isolated from the ethanolic extract of the aerial part of Mananthes patentiflora. The structure elucidation of these compounds was mainly established on the basis of 1D NMR, 2D NMR and HR-MS spectroscopic analysis. 相似文献
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Jun-Mian Tian Ying-Tong Di Xian-Wen Yang Zhu-Lin Gao 《Journal of Asian natural products research》2013,15(3):228-232
Three new lignan glycosides, mananthosides I–K (1–3), were isolated from the ethanolic extract of the aerial part of Mananthes patentiflora. The structure elucidation of these compounds was mainly established on the basis of 1D NMR, 2D NMR and HR-MS spectroscopic analysis. 相似文献
12.
R C Barbosa F Riet-Correa R M T Medeiros E F Lima S S Barros E J Gimeno R J Molyneux D R Gardner 《Toxicon》2006,47(4):371-379
A disease of the nervous system was observed in goats from two farms of the semiarid of the state of Paraíba, northeastern Brazil. Ipomoea sericophylla was found in one farm and I. riedelii in the other. Both plants were administered experimentally to five goats each. Both plants induced clinical signs similar to those observed in spontaneous cases. Two goats died spontaneously and five were euthanatized. Three goats recovered after the withdrawal of the plants. Histological examination showed that all goats that died spontaneously or were euthanized had diffuse vacuolation of neurons, macrophages of lymphatic tissues, and epithelial cells of pancreas, thyroid, renal tubules and liver. On electron microscopy of Purkinje cells, numerous dilated membrane bordered vacuoles were identified as lysosomes. On lectin-histochemical analysis, cerebellar cells gave positive reactions to Concanavalia ensiformis, Triticum vulgaris, and succinylated-T. vulgaris, which indicate the storage of alpha-D-mannose, alpha-D-glucose, beta-D-N-acetyl-glucosamine, and acetyl-neuraminic acid. The chemical analysis of I. sericophylla and I. riedelii showed 0.11 and 0.14% of swainsonine, respectively. The latter also contained calystegines B1, B2 and C1. It is concluded that I. sericophylla and I. riedelli cause a lysosomal storage disease. 相似文献
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Jian-Bo Yang Li Li Zhong Dai Yu Wu Xing-Chao Geng Bo Li 《Journal of Asian natural products research》2016,18(9):813-822
Four new dianthrone glycosides, named polygonumnolides C1-C4 (1–4), were isolated from the dried roots of Polygonum multiflorum Thunb, together with two known emodin dianthrones (5–6). Their hepatotoxicities were evaluated against L-02 cell lines. Compounds 1–4 showed weak hepatotoxicity against L-02 cell lines with IC50 values of 313.05, 205.20, 294.20, and 207.35?μM, respectively. 相似文献
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Xin-Jia Yan Xin-Yu Bai Qing-Bo Liu Shen Liu Pin-Yi Gao Ling-Zhi Li 《Journal of Asian natural products research》2013,15(4):376-382
Two new glycosides suspensaside C (1) and 2,3,5,6-tetrahydro-jacaranone-4-O-β-d-glucopyranoside (2), together with four known compounds suspensaside A (3), rengynic acid-1′-O-β-d-glucopyranoside (4), forsythoside A (5), and rengynic acid (6), were isolated from the fruits of Forsythia suspense (Thunb.) Vahl. The structures of 1 and 2 were elucidated on the basis of chemical and spectral analysis, including 1D, 2D NMR analyses and HR-ESI-MS. All isolates were tested for their cytotoxicities against five human cancer cell lines (A549, Colo-205, Hep-3B, HL60, and KB). Compound 3 exhibited cytotoxicity against HL-60, Hep-3B, and A549 cancer cell lines. 相似文献
15.
Fa-Sheng Li Liang Xu Xiao-Feng Chi Ting-Guo Kang Hai-Xue Kuang 《Journal of Asian natural products research》2013,15(7):639-642
Two new phenolic glycosides were isolated from the seeds of Cucurbita moschata. Their structures were elucidated as (2-hydroxy)phenylcarbinyl 5-O-benzoyl-β-d-apiofuranosyl(1 → 2)-β-d-glucopyranoside (1) and 4-β-d-(glucopyranosyl hydroxymethyl)phenyl 5-O-benzoyl-β-d-apiofuranosyl(1 → 2)-β-d-glucopyranoside (2) on the basis of spectroscopic analysis and chemical evidence. 相似文献
16.
From the roots ofAngelica dahurica Bentham et Hooker (Umbelliferae), five known coumarin glucosides together with adenosine have been isolated and identified
as nodakenin, 3′-hydroxymarmesinin, tert.-O-β-D-glucopyranosyl-byakangelicin, sec.-O-β-D-glucopyranosyl-byakangelicin and scopolin. This is the first report of the occurrence of these compounds in this plant. 相似文献
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Ze-Qing Zhao Fei Yang Xiu-Mei Gao Tian-Xiang Li 《Journal of Asian natural products research》2016,18(12):1151-1157
Two new lignan glycosides, ussuriensislignan A (1) and ussuriensislignan B (2), together with seventeen known compounds (3–19), were isolated from the fruits of Pyrus ussuriensis. Their structures were determined by various spectroscopic methods. This is the first report of the isolation of lignans (compounds 1–3) from the genus Pyrus, and compounds 3–6, 12–16 were reported from Pyrus for the first time. 相似文献
18.
Jiang Hu Yan Song Hui Li Xia Mao Xiao-Dong Shi 《Journal of Asian natural products research》2013,15(3):262-267
A phytochemical investigation on the 70% EtOH extract from the dry fronds of Diplopterygium rufopilosum afforded two new labdane-type diterpene glycosides, (3β,13S)-3-O-β-d-glucopyranosyl-13-O-α-l-rhamnopyranosyl-labda-8(17),14-diene (1) and (3β,13S)-3-O-α-l-rhamnopyranosyl-13-O-[6-O-acetyl-β-d-glucopyranosyl-(1 → 4)-2-O-acetyl-α-l-rhamnopyranosyl]-labda-8(17),14-diene (2). Their structures were determined on the basis of chemical method and spectroscopic analyses, including 1D and 2D NMR (COSY, HMQC, HMBC, and NOESY) and HR-ESI-MS analyses. 相似文献
19.
Min-Hua Peng Wei-Ping Dai Si-Jun Liu Liang-Wen Yu Yi-Na Wu Rui Liu 《Pharmaceutical biology》2016,54(10):2127-2134
Context The roots of Ilex asprella (Hook. et Arn.) Champ. ex Benth. (Aquifoliaceae) are widely used in Chinese medicine to treat influenza, amygdalitis, pertussis, etc. Their mechanism of action is still unknown, which raises the need to identify new bioactive compounds in this plant.Objective In this study, we isolated a novel saponin containing sulphonic groups, namely, asprellcoside A (1) and a known phenolic glycoside compound (2) from the roots of Ilex asprella and evaluated their bioactivities.Materials and methods Molecular structures were elucidated by analysing their spectral and chemical properties. The viability of A549 cells was tested using a MTT assay. Ability of the compounds to inhibit viruses was determined using the neuraminidase activity assay. Their anti-inflammatory effects were tested using the IP-10 activity assay using various concentrations (compound 1: 0.6, 0.2, 0.6, 1.70, 5.00 and 15.00?μM; compound 2: 0.4, 1.2, 3.6, 11.0, 33.0 and 100?μM). Their inhibitory effect on platelet aggregation induced by adenosine diphosphate (ADP) in rabbit plasma was determined at 60 and 80?μM.Results Both compounds inhibit influenza virus strain A/PuertoRico/8/1934 (H1N1) strongly with EC50 values of 4.1 and 1.7?μM, respectively. Both compounds inhibit the secretion of IP-10 with EC50 values of 6.6 and 2.5?μM, respectively. Compound 1 alone inhibited platelet aggregation significantly, with the rate of suppression being 47?±?8 and 38?±?3%, at 60 and 80?μM, respectively.Conclusions The results suggest that both compounds may be valid therapeutics against influenza virus infection and that compound 1 may be a novel agent for treating thrombosis. 相似文献
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Yan-Fei Liu Dong Liang Huan Luo Zhi-You Hao Yan Wang Chun-Lei Zhang 《Journal of Asian natural products research》2013,15(1):11-19
Four new ionone and ionone glycosides (1–4), and a new monoterpene (5), together with 10 known analogues (6–15), were isolated from the air-dried roots of Rehmannia glutinosa. The structures of these compounds were elucidated on the basis of spectroscopic data analysis. Furthermore, in in vitro assays, compound 3 (10 μM) exhibited moderate hepatoprotective activities against d-galactosamine-induced HL-7702 cell damage. 相似文献