温针加穴位注射夹脊穴治疗颈椎病疗效观察附:200例病例报告

目的观察总结用温针加穴位注射治疗颈椎病疗效.方法将符合颈椎病病诊断的200例患者按就诊顺序随机分为观察组和对照组2组,每组各有患者100例.观察组用温针加穴位注射夹脊穴治疗.对照组用单纯电针夹脊穴治疗.结果治疗组治愈率为84.00%,总有效率为97.00%,对照组治愈率为64.00%,总有效率为86.00%两组治愈率和总有效率之差异,有高度统计学意义(P<0.01).在疗程方面,观察组经1-2疗程治愈者,其构成比高于对照组(P<0.01).结论温针加穴位注射治疗颈椎病疗效优于电针组,具有疗效高,疗程短的优点.     

电针配合穴位注射治疗动眼神经麻痹52例临床观察

[目的]观察电针配合穴位注射治疗动眼神经麻痹52例临床疗效.[方法]将104例患者随机分为2组.治疗组52例采用电针配合太阳穴注射复方樟柳碱注射液治疗;对照组52例采用单纯电针治疗.观察2组的总体临床疗效.[结果]治疗组痊愈38例,有效10例,无效4例,总有效率为92.3%;对照组痊愈27例,有效13例,无效12例,总有效率为76.9%.2组比较差异有显著性意义(P<0.05),说明治疗组疗效优于对照组.[结论]电针配合太阳穴注射复方樟柳碱注射液治疗动眼神经麻痹疗效显著,比单纯电针治疗具有明显优势,值得临床推广应用.     

穴位注射配合电针治疗桡神经麻痹

采用维生索B1维生素B12穴位注射配合电针治疗桡神经麻痹80例,设单纯电针组做对照组,观察两组的临床疗效.结果 观察组总有效率为100%,对照组总有效率为87.5%,经统计学处理P＜0.05.两组问差异有显著性.结论 观察组疗效优于对照组.     

电针配合穴位注射治疗椎动脉型颈椎病的临床疗效观察

目的观察电针配合穴位注射治疗椎动脉型颈椎病的临床疗效。方法将70例患者随机分为治疗组(35例)和对照组(35例),治疗组采用电针配合穴位注射治疗,对照组仅采用电针治疗。结果治疗组痊愈率为54.3%,对照组痊愈率为28.6%,治疗组痊愈率优于对照组,两组痊愈率差异有统计学意义(P<0.05)。结论电针配合穴位注射治疗椎动脉型颈椎病优于单纯电针治疗。     

电针配合穴位注射转移因子治疗带状疱疹后遗症63例

目的观察电针配合穴位注射转移因子治疗带状疱疹后遗神经痛的临床疗效。方法采用电针配合穴位注射转移因子治疗带状疱疹后遗神经痛63例,与单纯电针治疗带状疱疹后遗神经痛60例进行对照观察。结果治愈率和总有效率治疗组为58.7%,95.24%,对照组分别为38.3%和81.67%,2组疗效比较,治疗组优于对照组。结论电针配合穴位注射转移因子治疗带状疱疹后遗神经痛的疗效显著,方法简便,利于在基层医院推广使用。     

针刺加穴位注射治疗颈型眩晕的临床研究

目的:观察针刺加穴位注射治疗颈型眩晕患者的临床疗效,探讨针刺加穴位注射治疗颈型眩晕的作用机制。方法:用临床实验的方法,针刺加穴位注射治疗32例颈型眩晕患者作为治疗组,单纯使用药物治疗颈型眩晕28例患者作为对照组,两组患者各自治疗1个疗程,分别观察两组患者的临床疗效。结果:针刺加穴位注射治疗组32例患者,总有效率93.75%。对照组单纯使用药物治疗颈型眩晕患者28例,总有效率50%,两组患者比较有显著性差异,P<0.05。结论:针刺加穴位注射治疗颈型眩晕效果优于单纯药物治疗,且可以减少药量,提高疗效,无不良反应。     

毫针穴位透刺配合红外线光浴治疗周围性面瘫60例护理

目的 观察电针配合红外线光浴治疗面瘫的疗效.方法 将60例患者随机分为两组,各30例.观察常规电针加红外线光浴治疗,对照组单纯常规针刺接电针.最后评定临床疗效.结果 观察组和对照组治愈率分别为76.670、50%.两组总有效率分别为93.33%、76.67%.结论 毫针配合红外线光浴治疗周围性面瘫,均有良好效果.而且穴位透刺配合红外线光浴治疗优于单纯常规针刺治疗.     

电针配合穴位注射治疗强直性脊柱炎的临床研究

目的:比较电针配合穴位注射治疗强直性脊柱炎的临床疗效差异。方法:将60例强直性脊柱炎患者随机分为两组,治疗组30例采用电针配合穴位注射方法治疗,对照组30例采用静滴鹿瓜多肽治疗,进行疗效对比。结果:两组患者治疗后总疗效分析,治疗组总有效率93.33%,控显(近期控制和显效)率66.67%;对照组总有效率76.67%,控显率40%,两组总疗效比较有统计学意义(P<0.05)。结论:电针配合穴位注射治疗强直性脊柱炎疗效优于鹿瓜多肽组。     

电针、穴位注射结合西药治疗胸腰椎压缩性骨折临床疗效观察

目的比较电针、穴位注射结合西药治疗与单纯西药治疗老年性骨质疏松所致胸腰椎压缩性骨折的疗效差异。方法将符合诊断的86例胸腰椎压缩性骨折患者随机分为观察组43例和对照组43例。对照组予口服钙尔奇D片,并静滴骨肽注射液20 mL;观察组在上述治疗的基础上加用电针相应的夹脊穴,并穴位注射当归针及复方丹参针。两组均治疗20 d后,观察并评价临床症状的改善情况。结果对照组:治愈8例,好转26例,未愈9例,总有效率79.1%;观察组:治愈14例,好转27例,未愈2例,总有效率95.3%。结论电针、穴位注射结合西药治疗老年性骨质疏松所致胸腰椎压缩性骨折疗效明显优于单纯西药治疗(P0.05)。     

三联疗法治疗肩关节周围炎临床研究

目的:观察三联疗法(温针灸、穴位注射、超短波)治疗肩周炎的临床疗效。方法:将110例肩周炎患者随机分为两组,治疗组和对照组,每组各55例;治疗组采用温针灸、穴位注射配合超短波治疗,对照组采用电针治疗;两组在治疗3个疗程后进行疗效评定。结果:治疗组总有效率为98.2%,临床治愈率为78.1%;对照组总有效率为78.1%,临床治愈率为23.6%,治疗组总有效率及临床治愈率均优于对照组,两组比较差异具有统计学意义(P<0.05)。结论:温针灸加穴位注射配合超短波治疗肩周炎具有较好临床疗效。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.