腹腔镜下腹壁巨大切口疝修补术的临床分析

目的 探讨腹腔镜下应用补片修补腹壁切口疝的手术方法及临床效果.方法 回顾性分析41例腹壁切口疝行腹腔镜下补片修补术患者的临床资料.结果 38例均顺利完成手术, 3例中转开腹.手术时间 78～186 min,平均 95 min.术后疼痛轻微,术后排便、排气时间 25～41 h,平均 32 h.术后第 2 d进食.术后住院 5～7 d,平均 6 d.41例随访 6～16个月,平均 9个月,未见疝复发.结论 腹腔镜下采用复合补片修补腹壁切口疝是一种安全、有效的方法,值得临床推广应用.     

老年腹壁切口疝的腹腔镜下修补术

目的 探讨腹腔镜下应用补片行老年腹壁切口疝修补术的方法、安全性及临床效果。方法 2004年11月至2006年6月对17例老年切口疝患者行腹腔镜下应用补片切口疝修补术。结果 16例腹腔镜下行腹腔粘连松解和补片固定,顺利完成切口疝修补手术,1例因肠管与腹壁粘连紧密而中转开腹修补术。手术时间65～132min,平均95min。术后恢复排便、排气时间平均为31h,术后住院5～7d。术后并发症：疼痛3个月以上者3例,浆液肿5例,穿刺口感染1例,均经保守治疗后好转,无手术死亡和肠瘘发生。随访7～26个月（平均13个月）,未见切口疝复发。结论 腹腔镜下行腹腔内粘连松解,采用缝合器和缝线贯穿腹壁固定补片修补老年腹壁切口疝安全、有效。     

腹腔镜腹壁切口疝补片修补术的应用体会

目的：探讨腹腔镜腹壁切口疝补片修补术的临床应用价值及安全性。方法：2005年8月至2006年10月我院为8例腹壁切口疝患者使用自膨胀式聚丙烯-膨化聚四氟乙烯双面复合型补片行腹腔镜腹壁切口疝修补术，其中2例联合行胆囊切除术。结果：8例手术均获成功，手术时间55～150min，平均85min，无手术死亡病例及并发症发生，患者术后8～24h后下床活动，1—2d排气，术后疼痛轻，2—3d后完全缓解，3—7d（平均4d）患者顺利康复出院。随访12～24个月无复发。结论：腹腔镜腹壁切口疝修补术安全可靠，具有创伤小、术后康复快、并发症少、不增加手术穿刺孔、可完成联合手术等优点，临床应用前景广阔。     

腹腔镜下腹壁切口疝修补术(附41例报告)

目的探讨腹腔镜下采用聚丙烯和膨化聚四氟乙烯复合补片（Bard Composix Mesh）修补腹壁切口疝的效果。方法2004年10月～2005年8月，对41例切口疝（腹壁缺损长径3～25cm，宽径3～18cm）腹腔镜下用超声刀进行腹腔内粘连松解和采用强生疝修补用缝合器行补片固定修补术。结果41例均顺利完成，无中转开腹。手术时间60～182min，平均85min。术后疼痛轻微，术后排便、排气时间25～41h，平均32h。术后第2天进食。术后住院5～7d，平均6d。41例随访6～16个月，平均9个月，未见切口疝复发。结论腹腔镜下采用复合补片修补腹壁切口疝是一种安全、有效的方法，值得临床推广应用。     

腹腔镜下腹壁切口疝修补术

目的探讨腹腔镜下应用补片行腹壁切口疝修补术的方法、安全性及临床效果。方法2004年9月至2007年6月对56例切口疝（腹壁缺损长径7～19cm,宽径4～12cm）的患者行腹腔镜下应用补片行切口疝修补术。结果55例腹腔镜下行腹腔粘连松解和补片固定,顺利完成切口疝修补手术,1例因肠管与腹壁粘连紧密而中转开腹修补术。手术时间60～135min,平均92min。肠功能恢复早,术后排便、排气时间平均为31h,术后住院5～7d。术后并发症：术后疼痛达3个月以上者有9例,浆液肿8例。无手术死亡和肠瘘发生。随访16～28个月,平均19个月,未见切口疝复发。结论腹腔镜下行腹腔内粘连松解、采用缝合器和缝线贯穿腹壁固定补片来修补腹壁切口疝是一种安全、有效的微创方法,值得临床推广应用。     

腹腔镜下修补70岁以上患者腹壁切口疝(附8例报道)

目的初步探讨并总结腹腔镜下腹腔内置补片法修补70岁以上老年患者腹壁切口疝的临床经验。方法回顾性分析了我院2005年7月至2008年7月期间实施的8例腹腔镜下腹腔内置补片法修补70岁以上老年患者腹壁切口疝的临床资料。结果8例中有1例因腹腔粘连严重而中转开腹手术,其余7例均成功完成腹腔镜下疝修补手术;手术时间50～180min,平均105min;术后1例发生高碳酸血症导致昏迷,经呼吸机辅助呼吸24h后好转;1例发生血清肿,1例术区明显疼痛超过1个月,均经保守治疗治愈;住院时间7～14d,平均9.5d。术后随访12～36个月(平均26.5个月)无复发,无局部不适。结论腹腔镜下腹腔内置补片法修补70岁以上患者的腹壁切口疝是安全、可行的,且具有微创、恢复快等优点,但必须注意围手术期处理及手术技巧。     

腹腔镜下腹壁巨大切口疝修补术的临床应用

目的探讨腹腔镜下应用补片修补巨大腹壁切口疝的手术方法及临床效果。方法分析25例应用腹腔镜下补片修补腹壁巨大切口疝(腹壁缺损长径为12~25cm,宽9~18cm,缺损面积108~451cm2)患者的临床资料。结果21例(84.0%)顺利完成腹腔镜下腹壁切口疝修补术,4例(16.0%)因肠管与腹壁粘连紧密而中转开腹。手术时间78~186(平均95)min。术后住院5~8d,平均6.5d。术后疼痛达3个月以上8例(32.0%),经治疗后缓解;浆液肿9例(36%)。无切口感染和肠瘘发生;无手术死亡。全组患者随访6~25(平均11)个月,无切口疝复发。结论腹腔镜下修补腹壁巨大切口疝是一种安全、有效的方法,对腹腔粘连重分离困难者应及时中转开腹。     

腹腔镜下腹壁切口疝修补术20例

目的 探讨腹腔镜治疗腹壁切口疝的安全性及有效性.方法 回顾性分析2009年6月至2011年9月20例腹壁切口疝患者的资料.其中男14例,女6例,年龄26 ～ 76岁,平均57.3岁.距离上次手术时间间隔为4～26个月,平均7个月.腹正中切口13例,侧腹部切口7例.有2例为缝合修补术后复发病例.结果 所有患者均采用复合补片进行修补,腹壁缺损大小4cmx5cm～ 10cm×13 cm.手术时间40～ 170 min,平均100 min.术后所有患者切口Ⅰ期愈合,术后补片上方疝囊内积液5例,经局部穿刺抽吸并加压包扎后治愈.术后修补区域腹壁疼痛1例,给予口服美洛昔康片对症处理,于术后3个月内逐渐消失.术后住院时间4～13d,平均7d.18例患者获得随访,随访6～30个月,平均15个月,1例复发.结论 腹腔镜下复合补片修补腹壁切口疝具有损伤小、术后疼痛轻、并发症少、恢复快等优点,值得推广.     

腹腔镜腹腔内补片置入术在半月线疝修补中的应用

目的探讨腹腔镜腹腔内补片置入术行半月线疝修补的临床效果。 方法2010年10月至2016年12月,复旦大学附属中山医院闵行分院在腹腔镜下对11例半月线疝患者进行修补治疗。手术采用超声刀进行疝环周围组织分离后,应用螺旋钉联合补片四角悬吊将防粘补片固定覆盖疝环完成半月线疝修补术。分析总结腹腔镜腹腔内补片置入术行半月线疝修补的临床效果。 结果11例患者均成功地在腹腔镜下行腹腔内补片置入无张力半月线疝修补术。手术时间30～60 min,平均40 min。术中出血10～20 ml,平均15 ml。患者术后排气、排便时间18～30 h,平均25 h。术后住院3～7 d,平均5.5 d。住院期间均未发生感染,无手术副损伤和死亡病例,2例患者发生血清肿。所有患者均获随访,时间6～50个月,未发现复发病例。 结论腹腔镜腹腔内补片置入术修补半月线疝具有创伤小、恢复快、并发症少等优点,符合疝无张力修补原则。     

腹腔镜下切口疝补片修补术的临床应用

目的 探讨腹腔镜下腹壁切口疝修补术的手术方法、安全性等问题。方法对2004年3月至2006年5月79例行腹腔镜下补片修补术治疗腹壁切口疝病人的临床资料进行分析。结果 78例（98．7％）手术成功，1例因腹腔内广泛粘连而中转开放修补。平均手术时间为88min，平均术后住院4．6d，18例（22．8％）病人术中发现有1个以上的隐匿性缺损。术后并发症：术后短期内修补区腹壁明显疼痛58例（73．4％）。腹壁缝合点较长时间疼痛6例（7．6％），浆液肿14例（17．7％），无手术死亡，1例术后出现肠瘘，经保守治疗好转，1例腰部切口疝的病人术后复发。结论 多数病人腹壁切口疝可以经腹腔镜行粘连松解及补片修补术，并可在术中发现其他隐性缺损，手术安全性较高。对腹腔内广泛粘连而影响操作器械进入及粘连分离者，应及时中转开腹手术。     

2015年乳腺癌辅助化疗进展

【摘要】〓乳腺癌是危害我国女性健康的头号杀手,尽管近年来辅助化疗的研究进展突飞猛进,但临床中仍有不少问题未能明确,如辅助化疗的合适人群、化疗的开始时间、蒽环及紫杉类的地位和用法、强化维持治疗的作用、疗效及预后的生物标志物等。本文结合乳腺癌辅助化疗在临床上的常见问题和2015年各大乳腺癌会议阐述乳腺癌辅助化疗的最新进展。     

Organ allocation in pediatric transplantation in France

In France, ministerial decrees in 1995 and 1996 gave children under 16 who are awaiting transplantation national priority for kidneys and livers from donors under 16, and regional priority for kidneys and livers from donors under 30. We analyzed the effects of these changes on waiting time, death on the waiting list, and balance between demand and supply. The percentage of children who received a transplant during the year of registration increased from 40% in 1993 to 67% in 1998 for kidney transplantation, but only from 50% to 67% for liver transplantation. The number of new children registered on the renal transplant waiting list (84 in 1998) and the number transplanted (85 in 1998) are balanced. But, because of the number of children still on the waiting list at the end of each year, there remains an imbalance of about 70 for kidney transplantation. For liver transplantation, there remains an imbalance of about 35. Death on the renal transplant waiting list has been below 2% since 1993. Death on the liver transplant waiting list decreased from 10–20% in 1993–1995 to 3% in 1998. The number of children who died on the thoracic organ waiting list in 1998 was the same as the number transplanted. In conclusion, the new rules governing organ allocation to children in France have shortened waiting time for renal transplantation, but not for liver transplantation. Many children still die on the waiting list for thoracic organ transplantation. Received: 4 July 2001 / Revised: 4 October 2001 / Accepted: 4 October 2001     

再次肝移植8例经验总结

目的总结再次肝移植的临床经验。方法回顾分析我中心再次肝移植病人临床资料，并结合文献进行讨论。结果共有8例病人接受了再次肝移植术，再次肝移植率为3．64％，再次移植原因中慢性排异反应2例、胆道缺血性病变5例、肝动脉栓塞1例。术后5例恢复顺利痊愈出院，已分别存活8、7、4、3、1个月，3例死亡，1例死于感染性休克，1例死于多器官功能衰竭，1例死于颅内出血。结论再次肝移植能有效挽救移植肝失功病人的生命，再移植指征的掌握、手术时机的选择、手术技巧的提高和围手术期的正确处理是提高再次移植成功率的关键。     

Current antibiotic prophylaxis in pancreatoduodenectomy in Japan

Background/Purpose The aim of this study was to investigate the current use of antibiotic prophylaxis (AP) in association with pancreatoduodenectomy (PD) in Japan, and to determine its surgical implications.Methods We surveyed 2331 patients who underwent PD for treatment of disease in the periampullary region. Data, obtained during the period January 2002 through December 2003, from 111 major surgical services associated with the Japanese Society for Pancreatic Surgery, were analyzed with regard to patient characteristics, preoperative complications, AP, and postoperative morbidities.Results Eighty-five (78.7%) of the 108 eligible institutions chose a first- or second-generation cephalosporin for AP, given for a mean duration of 4.3 days. At all but 1 institution, the first dose was administered prior to surgical incision of the skin. At 42% of the institutions, an additional antibiotic was administered during surgery. The overall rate of wound infection was 6.8% of the 2266 patients for whom data were available. Preoperative jaundice was found in 55.3% of these 2266 patients, and 92.6% of these jaundiced patients were suffering from preoperative infections. In addition, those with preoperative infections were also diagnosed as having biliary infections. The number of patients with preoperative jaundice in combination with preoperative infections was significantly related to the rate of postoperative morbidity (P < 0.0001).Conclusions Administration of AP in association with PD in Japan seems appropriate. Icteric patients with biliary infections are at high risk for postoperative morbidities and need careful monitoring after surgery.A summary of this survey was presented, in part, at the 31st Annual Meeting of the Japanese Society for Pancreatic Surgery, May 2004, Osaka, Japan     

Advances in analgesia in the older patient

The average age of the world's population is increasing rapidly, with those over 80 years of age the fastest growing subsection of older persons. Consequently, a higher proportion of those presenting for surgery in the future will be older, including greater numbers aged over 100 years. Management of postoperative pain in these patients can be complicated by factors such as age and disease-related changes in physiology, and disease-drug and drug-drug interactions. There are also variations in pain perception and ways in which pain should be assessed, including in patients with cognitive impairment. Alterations in pharmacokinetics and pharmacodynamics may influence drugs and techniques used for pain relief. The evidence-base for postoperative pain management in the older population remains limited. However, most commonly used analgesic regimens are suitable for older patients if adapted and titrated appropriately.     

Urologic diseases in america project: trends in resource use for urinary tract infections in men

PURPOSE: Various types of urinary tract infection (UTI) occur in men. In this study we examined health care use trends, including epidemiological and economic factors, for UTI in men in the United States. MATERIALS AND METHODS: The analytical methods used to generate these results have been described previously. RESULTS: Approximately 20% of all UTIs occur in men. Between 1988 and 1994 the overall lifetime prevalence of UTI was estimated to be 13,689/100,000 men. Orchitis rates, particularly in older men, are generally higher than those of cystitis or pyelonephritis. Approximately 10% of all inpatient care of men with UTI is for orchitis (12 to 14/100,000 population). Rates of outpatient hospital and physician office care for male UTI have increased in the last decade. Rates for emergency room care for UTI in elderly men (85 to 94 years old) were almost twice those in men younger than 85 years. The adjusted mean health care expenditure for privately insured men with UTI was 5,544 dollars in 1999 compared to 2,715 dollars for men without UTI. Total annual health care expenditures for men and women with UTI were 5,544 dollars and 5,407 dollars, respectively. Mean time lost from work was slightly higher for men. Based on composite data overall medical expenditures for men with UTI in the United States were estimated to be approximately 1.028 billion dollars in 2000. CONCLUSIONS: Health care use and economic data on UTIs in men revealed a number of intriguing trends. These results raise various important questions for future research.     

Management of osteoporosis in primary care in Australia

Summary  This study reviewed factors influencing osteoporosis management in primary care settings in Australia and examined risk profiles of patients (n = 37,957) for osteoporosis. Only 29.7% of patients with a prior fracture were currently on specific medication for osteoporosis. The results highlight the need for further exploration of barriers to osteoporosis management. Introduction  Osteoporosis management in primary care is suboptimal even for high-risk people with a history of prior fracture. Methods  This study reviewed factors influencing the management of individuals at risk for osteoporosis in primary care settings in Australia and examined risk profiles of patients for osteoporosis. Patients (n = 37,957, mean age 71) were recruited over a 12-month period (February 2006–Jan 2007) and interviewed. Results  With regard to risk factors for osteoporosis, 12.6% of patients reported a history of prior minimal trauma fracture, 7.5% reported a family history of osteoporosis, 7.4% reported they were current smokers, 11.4% reported low dietary calcium intake, 31.8% reported no regular weekly physical exercise and 10.3% reported current use of glucocorticoids. Of those with a prior fracture, only 29.7% were currently on specific medication for osteoporosis. Radiography (n = 17,754) demonstrated a prior vertebral fracture in 30.1%, but only 3.8% of the 17,754 patients reported current use of specific osteoporosis medication. Conclusions  This study has confirmed low rates of treatment in primary care even in individuals who have already suffered a prior fracture or have other risk factors. This study highlights the need for further exploration of barriers to osteoporosis management in the primary care setting.     

Inequality in access to coronary revascularization in Sweden

OBJECTIVES: To investigate social and gender equality in access to coronary revascularization for those treated for coronary heart disease in Sweden between 1991 and 2000. DESIGN: All Swedish residents between 25 and 74 years old with a hospital stay for coronary heart disease were eligible for the study, in total about 153,000 persons. The Swedish Hospital Discharge Register from 1988 through 2000 was used to define the study population. Poisson regression analyses were used to estimate the effect of socio-economic status on the likelihood for coronary artery bypass grafting (CABG) within 2 years. In the analysis of gender differences, the likelihood for percutaneous coronary intervention (PCI) was also included. RESULTS: Males were 1.5 times more likely to undergo revascularization procedures than females even after adjusting for confounding factors and the fact that women are less eligible for interventions. The analyses also showed significant socio-economic inequalities in access to CABG among men, but not among women. CONCLUSIONS: There are gender and socio-economic inequalities in access to cardiac procedures in Sweden.     

Trends in prevalence of diabetes in Asian countries

Diabetes is a major lifestyle disorder,the prevalence of which is increasing globally.Asian countries contribute to more than 60% of the world’s diabetic population as the prevalence of diabetes is increasing in these countries.Socio-economic growth and industrialization are rapidly occurring in many of these countries.The urban-rural divide in prevalence is narrowing as urbanization is spreading widely,adversely affecting the lifestyle of populations.Asians have a strong ethnic and genetic predisposition for diabetes and have lower thresholds for the environmental risk factors.As a result,they develop diabetes at a younger age and at a lower body mass index and waist circumference when compared with the Western population.The adverse effect of physical inactivity and fatty food are manifested as the increasing rate of overweightness and obesity,even among children.The health care budgets for the disease management are meager and the health care outcome is far from the optimum.As a result,complications of diabetes are common and the economic burden is very high,especially among the poor strata of the society.National endeavors are urgently needed for early diagnosis,effective management and for primary prevention of diabetes.This editorial aims to highlight the rising trend in prevalence of diabetes in Asia,its causative factors and the urgent need to implement national strategies for primary prevention of type 2 diabetes.