真性小眼球继发青光眼的治疗

目的：探讨真性小眼球继发青光眼的临床特征，治疗方法以及并发症的防治措施。方法：回顾性分析了17只真性小眼球继发青光眼的临床资料，治疗方法及病情转归。结果：9例17只眼，眼轴14．36－19.33mm；均合并有高度远视，屈光度＋7．00－＋16．00D.有的患眼均有慢性闭角型青光眼的临床表现，其中9只进展期的患眼经过激虹虹膜手术联合药物治疗使青光眼得到控制，有1只眼在就诊时已是绝对期，予以睫状体光凝以改善疼痛症状，另外7只晚期患眼均接受了滤过手术，其中3只在随诊期内出现了严重眼后节并发症导致失明。结论：真性小眼球继发青光眼的治疗很复杂。在早期进行激光虹膜手术是治疗真性小眼球合并青光发安全有效的方法，选手选择密闭性的眼内手术和预防性的涡静脉减压术，前巩膜切开术，巩膜切除术可以减少滤过手术灾难性的眼后节并发症。     

Laser and unsutured sclerotomy in nanophthalmos

Among 30 eyes with nanophthalmos, 21 had angle-closure glaucoma and two had open-angle glaucoma associated with pseudoexfoliation of the lens capsule. Laser iridotomies, sometimes combined with laser iridoplasty, were sufficient to control, or to allow medical control of, the glaucoma in 15 of 18 eyes. Four eyes with uveal effusion underwent an unsutured sclerotomy or sclerectomy, and all had resolution of the choroidal detachment within two weeks. Cataract extraction improved the vision in seven of nine eyes. Previous or simultaneous sclerotomy or sclerectomy was performed on all nine eyes that underwent cataract extraction and in two eyes at the time of glaucoma surgery; no eye had postoperative uveal effusion or other major complications. Laser iridotomy and iridoplasty, sometimes with supplemental medical therapy, are often sufficient in the treatment of angle-closure glaucoma in nanophthalmos and are safer than surgery. Nanophthalmic uveal effusion can be prevented or treated with an unsutured sclerotomy or sclerectomy.     

Cataract surgery in patients with nanophthalmos: results and complications

PURPOSE: To evaluate the results and complications of cataract surgery in patients with nanophthalmos. SETTING: University hospital practice. METHODS: The records of consecutive patients with nanophthalmos who had cataract surgery from 1978 through 2002 were reviewed for ocular diagnoses, corneal diameter, keratometry, axial length, retinal-choroidal-scleral thickness determined by echography, ocular surgeries, visual acuity, and complications. RESULTS: Eight patients (6 women, 2 men) with a mean age of 59 years were reviewed. Four patients were not previously diagnosed with nanophthalmos; increased retinal-choroidal-scleral thickness (mean 2.41 mm) confirmed the diagnosis. Twelve eyes had cataract extraction with posterior chamber intraocular lens (IOL) implantation, 11 by phacoemulsification and 1 by extracapsular cataract extraction, and 4 eyes had lamellar scleral resections. Additional surgeries included glaucoma laser treatment (8 eyes), cyclocryotherapy (2 eyes), trabeculectomy with scleral resection (1 eye), trabeculectomy combined with phacoemulsification (1 eye), and neodymium:YAG laser capsulotomy (4 eyes). No eye lost vision; however, complications included severe iritis, broken IOL haptic with vitreous loss, posterior capsule opacity, choroidal hemorrhage, phthisis, and aqueous misdirection. CONCLUSIONS: Results indicate that echography should be used to assess retinal-choroidal-scleral thickness in eyes that are hyperopic and at risk for narrow-angle glaucoma. Thickening may confirm the diagnosis of nanophthalmos and allow careful preoperative assessment and appropriate operative procedures in these high-risk eyes. With advances in cataract, glaucoma, and uveal effusion treatments, surgical results in patients with nanophthalmos are improving.     

Nanophthalmos: A Perspective on Identification and Therapy

Nanophthalmos is a rare and blinding disease. Diagnostic features include a small eye, small cornea, shallow anterior chamber, narrow angle, high lens/eye volume ratio, and uveal effusion. Intraocular surgery has a high rate of disastrous complications and blindness. The 32 eyes (16 patients) presented are in three categories based on angle closure and intraocular pressure levels. Treatment methods included medication, laser iridotomy and gonioplasty, peripheral iridectomy, filtration surgery, and cataract extraction. Glaucoma medication was effective, although miotics sometimes increased pupillary block. Laser iridotomy was successful in 83% of six eyes; laser gonioplasty in 91.6% of 12 eyes. Peripheral iridectomy succeeded in two of seven eyes, and filtering operations provided tension control in two of five eyes. Thirteen of 15 eyes undergoing filtration surgery suffered severe postoperative visual loss. Cataract extraction improved vision in only three of six eyes. The authors’ experience confirms that surgery in nanophthalmic eyes has an extremely high complication rate with disastrous results. Medication and laser therapy are the procedures of choice for angle-closure glaucoma in nanophthalmos.     

Long-term results of pars plana vitrectomy combined with filtering surgery for neovascular glaucoma.

BACKGROUND AND OBJECTIVE: To analyze the effectiveness of vitrectomy combined with filtering surgery for neovascular glaucoma. PATIENTS AND METHODS: Twenty-one eyes with neovascular glaucoma underwent pars plana vitrectomy combined with filtering surgery between January 1995 and December 2003. Thirteen eyes (10 cases) had neovascular glaucoma secondary to proliferative diabetic retinopathy and 8 eyes (8 cases) had neovascular glaucoma secondary to central retinal vein occlusion. The initial intraocular pressures ranged from 21 to 70 mm Hg with full medication. All cases were observed for more than 12 months after the last surgery and the ophthalmic records were retrospectively reviewed. RESULTS: During the follow-up period, 19 eyes (90.5%) had intraocular pressures of less than 21 mm Hg with or without antiglaucoma eye drops, whereas 18 eyes (85.7%) had a stable or improved visual acuity. CONCLUSION: Vitrectomy combined with filtering surgery is considered to be an effective treatment for neovascular glaucoma to maintain the visual function for a long period.     

老年人青光眼51例临床分析

目的:分析老年人青光眼的发病特点及危险因素,以探讨防治措施.方法:对51例69眼50岁以上老年人已确诊为青光眼的病例进行发病特点及危险因素的问卷调查与分析.结果:患者51例中,急性闭角型青光眼急性发作期21例25眼(男4例5眼,女17例20眼)、慢性闭角型青光眼17例26眼(男6例9眼,女11例17眼)、开角型青光眼10例15眼(男6例9眼,女4例6眼)、继发性青光眼3例3眼(男2例2眼,女1例1眼).急性闭角型青光眼21例25眼急性发作均有明显诱因,症状明显.慢性闭角型青光眼及开角型青光眼14例22眼有轻微症状,开角型青光眼患者1例2眼有夜盲等症状,余无明显症状.继发青光眼中有2例有明显症状,1例无明显症状.有家族史者11例;解剖因素(浅前房、窄房角)有39例;近视及远视患者有21例;视网膜静脉阻塞致新生血管性青光眼1例;白内障膨胀期继发青光眼1例;长期点用含地塞米松眼药水致糖皮质激素性青光眼1例.结论:老年人青光眼病因复杂、临床表现多样,应给予患者相应的健康宣传,提高患者对疾病的认知能力,做到早就诊、早治疗.     

Outcome of early surgery for bilateral congenital cataracts in eyes with microcornea

PURPOSE: To report the outcome of early surgery for bilateral congenital cataracts in eyes with microcornea. DESIGN: Interventional case series. METHODS: We retrospectively reviewed 22 eyes of 11 patients with microcorneas who underwent early surgery for bilateral congenital cataracts. All patients underwent lensectomy and anterior vitrectomy via the limbal approach by 12 weeks of age. The corneal diameters at the time of surgery ranged from 7.0 to 9.0 mm. The mean age at the time of surgery was 7.7 +/- 3.3 weeks (range, two to 12 weeks); the follow-up period was 115 +/- 58 months (range, 40 to 199 months). Aphakic eyes were corrected with spectacles or contact lenses. Visual acuities and the postoperative complications were evaluated periodically. RESULTS: The morphologic types of cataract were nuclear (12 eyes), complete (eight eyes), and membranous (two eyes). Other preoperative ocular abnormalities included iris hypoplasia in 10 eyes and persistent fetal vasculature in three eyes. Systemic abnormalities were found in four patients. Postoperative complications occurred in 11 eyes (50%), including glaucoma (nine eyes), exudative retinal detachment (two eyes), rhegmatogenous retinal detachment, and secondary membrane formation, in one eye each. The binocular visual acuity was 20/40 to 20/20 in six patients (55%), 20/200 to 20/100 in two patients (18%), and 2/100 or worse in three patients (27%) who developed postoperative glaucoma. CONCLUSION: Despite microcorneas, favorable visual outcomes were achieved after early surgery in this series. However, adequate management of postoperative complications, especially glaucoma, is required.     

Treatment of glaucoma in young nanophthalmic patients

Purpose: To evaluate the criteria of diagnosis and management of secondary glaucoma in young nanophthalmic patients. Methods: Considering the anatomic features and clinical characteristics, 22 eyes of 11 patients were identified as bilateral nanophthalmos. Intraocular pressures (IOP) were checked with Goldmann applanation or Keeler pulse-air 2000 tonometer, and Nd-Yag laser was used for iridotomies. Prophylactic V-shaped unsutured sclerectomies over the pars plana were combined with trabeculectomy, and Mitomycin C (MMC) in 0.2 mg/ml concentration was applied. Results: Among 22 eyes of bilateral nanophthalmic patients 8 eyes had secondary angle-closure glaucoma. Laser iridotomies were performed in 6 eyes. Laser iridotomy and supplemental medical therapy were sufficient in 4 out of 6 eyes. Mean IOP dropped from 26.4 to 14.5 mmHg in these patients. Due to continuous increase of IOP in the other patients, they underwent trabeculectomy with V-shaped sclerostomy and intraoperative MMC application. Mean IOP dropped from 39.3 mmHg to 19.3 mmHg. Postoperative uveal effusion or other major complications were not observed. Mean age of these patients was 14.6 years during treatment. Conclusion: Management of glaucoma in nanophthalmus is complicated. Initial treatment is medical. If it is insufficient, laser iridotomies and V-shaped sclerostomies with filtration surgery can be performed at any age.     

青光眼顽固性高眼压的分期手术治疗

目的：分析青光眼顽固性高眼压状态下,先行睫状体光凝术降低部分眼压,Ⅱ期行进一步抗青光眼手术治疗的临床疗效观察。方法：回顾性分析北京华德眼科医院2013－01／2014－07收治的青光眼顽固性高眼压患者临床资料,共30例30眼,其中女12例,男18例,平均年龄56岁。这30眼中,急性闭角型青光眼急性发作期2眼,晶状体过熟期4眼,晶状体膨胀期6眼,新生血管性青光眼5眼,抗青光眼术后眼压仍不能控制正常9眼,玻璃体切除术后继发性青光眼4眼。所有患者入院后均首选睫状体光凝术,如果眼压未控制,则根据患者病情再行Ⅱ期抗青光眼手术。结果：在我们随访过程中,30例30眼均获得了满意效果,术前平均眼压62．79±5．59mmHg,一次睫状体光凝术后,眼压均有不同程度的下降,术后1wk,眼压降至32．84±8．16mmHg,其中6例完全控制正常,其余24例Ⅱ期再行进一步抗青光眼手术,术后眼压正常,术中无一例并发症出现。结论：青光眼顽固性高眼压状态下,先行睫状体光凝术控制眼压,可以大大减少二次手术时并发症的出现,后根据患者原发病的个体差异,Ⅱ期行进一步抗青光眼手术是一种安全有效的分期联合手术方式。     

老年性白内障膨胀期继发性青光眼的手术治疗

目的：探讨老年性白内障膨胀期继发生青光眼的手术时机，手术方式，手术并发症，方法：对21例22只眼行单纯白内障手术3只眼，白内障手术联合抗青光眼手术19只眼（其中小梁切除术17只眼，周边虹膜切除术2只眼），一期植入人工晶状体20只眼，结果：术后21只眼眼压正常，占85．45％，术后视力均较术前明显提高，术后视力≥0．3者占40．91％，结论：老年性白内障膨胀期继发性青光眼，根据发生作时房角是否开放选择恰当的手术方式可以提高视力及控制眼压，持续高眼压引起的视神经萎缩是术后视力低的主要原因，强调膨胀期白内障手术是预防老年白内障膨胀期继发性青光眼的重要措施。     

玻璃体切割合并滤过术治疗新生血管性青光眼

目的探讨玻璃体切割合并滤过术治疗新生血管性青光眼的疗效。方法对我院收治的13眼新生血管性青光眼施行了睫状体平坦部三切口闭合式玻璃体切割合并滤过术，其中新生血管性青光眼继发于增生性糖尿病视网膜病变9眼，继发于视网膜中央静脉阻塞4眼。术前视力为LP～0.1，术前眼压在药物控制下为21～70mmHg（1kPa=7．5mmHg），所有患者术后随访6个月。观察术后眼压和视力变化。结果随访期内，12眼眼压≤21mmHg（有／无抗青光眼药液滴眼），10眼视力保持稳定或有增进。结论玻璃体切割合并滤过术可有效地治疗新生血管性青光眼，并在较长时期内维持视觉功能。     

Risk profile of deep sclerectomy for treatment of refractory congenital glaucomas

OBJECTIVES: To evaluate the effectiveness and risk profile of deep sclerectomy in surgery for refractory congenital glaucoma. DESIGN: Retrospective non-comparative interventional case series. PARTICIPANTS AND INTERVENTIONS: Ten eyes of eight consecutive patients underwent deep sclerectomy for refractory congenital glaucoma. The procedure was converted to a trabeculectomy in four eyes and supplemented by a trabeculotomy in two eyes. Six eyes had primary congenital glaucoma, and four eyes had secondary congenital glaucoma. The patients' ages at the time of surgery in our department ranged from 8 months to 14 years. All eyes had a history of previous glaucoma surgery. MAIN OUTCOME MEASURES: The surgical outcome was assessed in terms of complication rate, intraocular pressure (IOP) change, need for surgical revision, or additional glaucoma medication. RESULTS: Preoperatively, the mean IOP was 31.9 mmHg (standard deviation [SD], 5.6 mmHg). At first follow-up 1 week after surgery, the mean IOP for all eyes was 12.7 mmHg (SD, 6.8 mmHg). The average reduction of IOP was statistically significant (P < 0.001). In accordance with the success criteria, all eyes were ultimately classified as failures. Average time to failure was 2.1 months (SD, 3.6 months). Specific complications were seen in terms of non-identification of Schlemm's canal (40%), choroidal deroofing (10%), and visible perforation of the trabeculodescemetic membrane (20%). Further complications were hyphema (40%), ocular hypotony (10%), vitreous hemorrhage (10%), and vitreous loss with subsequent retinal detachment (10%). CONCLUSIONS: Although deep sclerectomy may reduce the IOP in patients with refractory congenital glaucoma, this study indicates a specific risk profile associated with deep sclerectomy in surgery for refractory congenital glaucoma.     

儿童牵牛花综合征并发视网膜脱离的临床特征及治疗效果观察

目的 观察儿童牵牛花综合征（MGS）并发视网膜脱离（RD）的临床特征和治疗效果。方法 回顾分析经双目间接检眼镜、眼部B型超声、广角数码视网膜成像系统眼底照相、头颅磁共振和（或）磁共振脑血管造影检查确诊的49例MGS并发RD患儿51只眼的资料。其中,男性27例27只眼,女性22例24只眼。确诊时年龄为出生后1周~13岁,平均年龄（4.2±3.2）岁。RD类型能明确为渗出性RD者33只眼,孔源性RD者3只眼,其余15只眼不能明确RD类型。有20例20只眼合并其他先天性眼部异常。包括永存原始玻璃体增生症、先天性小眼球、脉络膜缺损、虹膜缺损。除并发RD外,还可并发白内障、瞳孔后黏连、继发性青光眼、角膜混浊、斜视、眼球震颤。22例22只眼进行了治疗。5例5只轻度渗出性RD眼患儿予口服醋甲唑胺治疗;3例3只眼行视盘周围激光光凝治疗;14例14只眼行手术治疗。手术治疗的14只眼中,6只眼仅MGS并发RD,行玻璃体切割手术,其中3只眼联合晶状体切除手术;8只眼伴继发性青光眼和并发性白内障,行单纯晶状体切除手术或超声乳化白内障吸除手术。治疗后随访时间均在3个月以上,平均随访时间（20.3±11.8）个月。对比治疗前后患儿视力、视网膜复位情况以及有无眼压升高等并发症。结果 5例口服醋甲唑胺治疗者随访期间病情稳定,RD未加重。3例视盘周围激光光凝治疗者中,2例病情稳定,1例在2次激光光凝治疗后RD范围扩大。行晶状体切除或超声乳化白内障吸除手术的8只眼中,手术后白内障解除,前房形成、眼压下降。行玻璃体切割手术的6只眼中,手术后视网膜平伏。进行治疗的患儿中,10例10只眼配合行视力检查。其中,1只激光光凝治疗眼的视力由治疗前手动提高至治疗后眼前数指,9只眼视力维持不变。未见其他与药物和手术治疗相关的并发症。结论 儿童MGS并发RD最早可发生在出生后1周,患儿往往还合并其他先天性眼部异常或眼疾病。定期随访,尽早发现RD,结合患儿病情进行药物、激光光凝或手术治疗,对保存患儿视功能有重要意义。     

Nd:YAG激光虹膜切除术治疗葡萄膜炎继发闭角型青光眼

目的 评价Nd：YAG激光虹膜切除术治疗葡萄膜炎继发闭角型青光眼的临床效果。方法 回顾性分析27例葡萄膜炎继发瞳孔阻滞闭角型青光眼经Nd：YAG激光虹膜切除术治疗的情况。随诊时间2月到4年。结果1)一次激光所有患眼均成功击穿虹膜。虽经术后积极抗炎治疗．12眼(44％)发生虹膜孔关闭。多次激光治疗后，最终89％的患眼获得了通畅的激光孔。2)在46次激光治疗中，击射点数为3～376点，激光能量为12～2077mJ。所用激光能量较原发闭角型青光眼高。3)75％的患眼激光治疗后眼压控制正常，6只眼(22％)眼压不能控制行滤过手术。4)激光手术的并发症主要是激光时虹膜的出血和暂时的眼压升高。5)术前有活动性炎症的患眼，发生激光孔闭合的比例更高。结论 Nd：YAG激光虹膜切除术是治疗葡萄膜炎继发闭角型青光眼的一种安全有效的方法。为提高手术的成功率，应在积极抗炎的同时，尽早行激光虹膜切除术。若激光后虹膜孔反复关闭，应考虑手术周边虹膜切除术。     

玻璃体切割术治疗非糖尿病性玻璃体出血

本文报告50例53眼非糖尿病性玻璃体出血的玻璃体切割术,术后视力进步的39眼(73.6%),其中达到0.05以上的27眼(50%).术后视力与病因及黄斑功能有关,其中以挫伤性玻璃体出血效果最好,全部视力有进步.其次为视网膜静脉周围炎,77%视力有进步.术后并发症中以玻璃体再出血及继发性青光眼多见,继发性青光眼中以血影细胞性青光眼为多(4/6).本文对手术时机,切割程度及血影细胞性青光眼进行了讨论.     

激光周边虹膜切除术治疗早期闭角型青光眼的临床观察

目的:YAG激光周边虹膜切除术治疗闭角型青光眼的疗效及并发症的临床观察。方法:本组病例20例(25眼),诊断为闭角型青光眼临床前期、前驱期的22眼,3眼为间歇期。使用Nd:YAG激光机在虹膜中周部单脉冲击射均为一次透切成功,随访3～12mo,观察疗效及并发症。结果:25眼激光切孔1次手术成功率100%。术后均出现了虹膜炎性反应,1～3h内一过性眼压升高5眼,前房出血4眼,角膜内皮损伤1眼,全部并发症于术后1～3d消失。无切孔后晶状体混浊及孔洞闭塞并发症发生。术后周边前房及房角增宽,眼压<18mmHg。结论:Nd:YAG激光周边虹膜切除术治疗闭角型青光眼安全有效,对早期患者效果更佳,适宜在基层医院推广。     

Ahmed青光眼阀植入联合视网膜光凝或冷凝治疗新生血管性青光眼

目的:探讨Ahmed青光眼阀植入联合视网膜光凝或冷凝术对新生血管性青光眼治疗的临床效果。方法:选取4a来住院的新生血管性青光眼56例58眼,其中视网膜中央静脉阻塞25例25眼,糖尿病性视网膜病变21例23眼,视网膜血管炎5例5眼,颈动脉狭窄4例4眼,视网膜分支静脉阻塞1例1眼,平均年龄50.6岁,均行Ahmed青光眼阀植入联合视网膜光凝或冷凝治疗,其中47眼于手术前后行全视网膜光凝,11眼于手术中联合周边视网膜冷凝术,平均随访18.0±6.2mo,观察手术前后视力和眼压的变化以及术后并发症的情况,结果进行统计学分析。结果:视力:术后43眼有不同程度地提高,15眼无变化,无视力下降者。眼压:随访6mo时眼压由术前49.56±8.25mmHg降至17.86±5.25mmHg,总成功率为85%;随访12mo时,眼压由术前50.25±7.18mmHg降至18.80±6.81mmHg,总成功率为78%;24mo以上随访19眼,眼压由术前51.05±8.10mmHg降至20.12±7.01mmHg,总成功率为74%,手术前后眼压比较差异有非常显著性。并发症主要有前房出血、前房延缓形成、引流管内口堵塞、引流盘纤维包裹,经术后处理均得到了恢复。结论:Ahmed青光眼阀植入联合视网膜光凝或冷凝是治疗新生血管性青光眼安全有效的方法之一。     

Cyclodiathermy: is it effective in the treatment of glaucoma?]

The authors describe the non penetrating technique of cyclodiathermy in the treatment of different types of glaucoma and publish the results and the complications of the application of this technique on thirty three eyes among their patients. These eyes included congenital glaucoma (8 eyes), aphakic glaucoma (5 eyes), after silicone surgery (5 eyes), neovascular glaucoma (4 eyes), traumatic glaucoma (4 eyes), secondary glaucoma (3 eyes), Sturge-Weber-Krabbe (2 eyes) and open angle glaucoma (2 eyes). Their study with a mean follow up of 2.5 years shows an overall success rate of 60%. The success is defined as an ocular tension less than or equal to 22 mmHg in the absence of serious complications. All the encountered complications are mentioned. Phtysis occurred in not more than 3% of cases (1 eye). They establish a comparison with the published results and complications of the other cyclodestructive procedures: Sonocare, transcleral laser Yag, transcleral laser Ruby and cyclocryotherapy. This comparison does not prove the superiority of these other procedures with regard to the non penetrating cyclodiathermy. They conclude that this non penetrating cyclodiathermy is a non expensive procedure which still have its good therapeutic value.     

原发性慢性闭角型青光眼年轻患者的临床研究

目的:探讨原发性慢性闭角型青光眼年轻患者临床治疗的经验和体会.方法:对2000-01/2005-12中山眼科中心临床收治的38例50眼、年龄＜40岁、临床确诊为进展期或晚期原发性慢性闭角型青光眼的患者、进行抗青光眼手术处理的病例进行回顾性分析.随访时间平均(23.6±7.5)mo;所有的病例都有完善的眼科检查.临床结果评价包括临床特点、手术结果和并发症.结果:患者平均年龄为(33.5±6.1岁;女性占60.5%;眼轴长平均(22.4±3.5)mm,其中短眼轴占18.0%,小眼球占14%;有60%的患者为浅前房(＜1.9 mm);超声生物显微镜检查高褶虹膜构型占80.6%,手术前后眼压差异有统计学意义(P＜0.001).4眼因眼压控制不理想,行二次抗青光眼手术治疗.术后并发症主要有浅前房(20%),恶性青光眼(12%).结论:对进展期或晚期的年轻原发性慢性闭角型青光眼患者进行复合式小梁手术治疗是行之有效的手段,但术后容易出现浅前房、恶性青光眼.术前详细检查、手术操作精细以及有效处理术后并发症将有助于提高手术成功率和减少并发症.     

Management of uveitic glaucoma with Ahmed glaucoma valve implantation

OBJECTIVE: To evaluate the safety and efficacy of Ahmed glaucoma valve implantation for the management of glaucoma associated with chronic uveitis. DESIGN: Retrospective, noncomparative case series. PARTICIPANTS: Nineteen patients (21 eyes) with chronic uveitis underwent Ahmed glaucoma valve implantation for uncontrolled glaucoma between 1995 and 1998. INTERVENTION: All patients had their uveitis controlled before surgery via immunomodulatory therapy. Ahmed glaucoma valve implantation was performed. Immunosuppression was continued in the early postoperative period for strict control of inflammation. MAIN OUTCOME MEASURES: Control of intraocular pressure (IOP). A secondary outcome measure was the number of antiglaucoma medications required to achieve the desired IOP. Visual acuity and complications associated with the surgery were monitored. RESULTS: The postoperative follow-up averaged 24.5 months. At the most recent visit, all 21 eyes had IOPs between 5 and 18 mmHg. The average pressure reduction after Ahmed glaucoma valve implantation was 23.7 mmHg. The average number of antiglaucoma medicines required to achieve the desired IOP was reduced from 3.5 before surgery to 0.6 after surgery. No eye lost even a single line of Snellen acuity at the most recent postoperative visit. Two eyes developed hypotony in the course of follow-up. One resolved without specific intervention, and the other eye required two autologous blood injections and tube ligature to correct the hypotony. One eye underwent Ahmed glaucoma valve replacement for abrupt valve failure. Two eyes underwent penetrating keratoplasty for reasons believed to be unrelated to the glaucoma surgery. Kaplan-Meier life-table analysis showed a cumulative probability of success after Ahmed glaucoma valve implantation of 94% at 1 year. CONCLUSIONS: Ahmed glaucoma valve implantation can be an effective and safe method in the management of uveitic glaucoma. The authors hypothesize that control of the patients' uveitis, through preoperative and long-term postoperative immunomodulatory therapy, may have contributed to the success rate reported herein.