Clinical Observation on Therapeutic Effects of the Point-Penetrating Method in Acupuncture Treatment of Spastic Hemiparalysis Due to Cerebrovascular Disorders

Objective: To observe the therapeutic effects of different acupuncture methods for spastic hemiparalysis due to cerebrovascular disorders. Methods: 90 cases of spastic hemiparalysis after wind-stroke were randomly divided into a control group of 30 cases, a body acupuncture group of 30 cases and a point-penetrating acupuncture group of 30 cases. All the patients were given 4 courses of treatment, with 7 sessions constituting one therapeutic course and with a one-day interval between courses. The evaluations were made 3 times, i.e. once before treatment and once every 15 days during the treatment. Results: The therapeutic effects in the point-penetrating acupuncture group were obviously superior to those of both the control group and the body acupuncture group. Conclusion: The point-penetrating acupuncture is an effective therapy for treating spastic hemiparalysis due to cerebrovascular disorders.     

Clinical Research of Acupuncture on Malignant Tumor Patients for Improving Depression and Sleep Quality

Objective:To study the effect of acupuncture on depression and insomnia of malignant tumor patients.Methods:Eighty cases of cancer related depression and sleep disorders were randomly divided into 2 groups:treatmentl group(acupuncture n=40) and control group(Fluoxetione n=40).All patients were assessed by Self-rating Depression Scale(SDS),Hemilton Depression Rating Scale(HAMD) and Pittsburgh Sleep Quality Index(PSQI) after treatment for 30 days.Results:Before treatment the SDS and HAMD scores of the trial group were 64.12±5.34 and 20.92±2.38,those of the control group were 64.24±4.98 and 20.72±2.74,after treatment the SDS and HAMD scores of the trial group were 43.64±5.28 and 9.88±1.27 respectively,significantly lower than those of the control group(50.76±5.42 and 13.72±2.05 respectively,both P<0.05).Before treatment the PSQI score of the trial group and the control group were 14.48±1.71 and13.92±2.59,after treatment the PSQI score of the trial group was 7.92±1.22 after treatment,significantly lower than those of the control group(11.44±1.89,P<0.01).Conclusion:Acupuncture can effectively reduce malignant-related depression,improve sleep quality,and help to improve the quality of life of cancer patients.     

The Qi-regulating Massotherapy for Treatment of Tonic Headache in 150 Cases

To observe the therapeutic effects of the qi-regulating massotherapy (通脉调气推拿法) for treatment of tonic headache. Ods: According to different clinical types, 150 cases of tonic headache were treaed by the qi-regulating massotherapy. Evaluations were done according to the scores for physiology, behavior, intensity of pain, and the therapeutic effects. Results: After treatment, the total score in the 150 cases significantly decreased as compared with that before treatment (P<0.01). The total effective rate was 93.3%, and the effective rates for all the types were over 90%. Conclusion: The qi-regulating massotherapy is indicated for all types of tonic headache with obvious therapeutic effects.     

A COMPARATIVE OBSERVATION ON TREATMENT OF HEART FAILURE DUE TO DIASTOLIC INSUFFICIENCY OF THE LEFT VENTRICLE -A Report of 43 Cases

43 cases of heart failure due to diastolic insufficiency of the left ventricle were treated with TCM differential treatment as the treatment group, the total effective rate being 86.0%. Statistically significant duTerence (P< 0.05) in the therapeutic effects was found between the treatment group and the control (25 cases) group. Improvement of the left ventricular diastole in the treatment group was more obvious than that of the control group (P< 0.01), while contractility of the left ventricle was also improved to a certain extent.     

Tiaobu Xinshen Recipe (调补心肾方) Improved Mild Cognitive Impairment of Alzheimer's Disease Patients with Xin (Heart) and Shen (Kidney) Deficiency

Objective: To observe the intervention effects of Tiaobu Xinshen Recipe(调补心肾方, TXR) on patients with mild cognitive impairment caused by Alzheimer's disease(MCI-AD). Methods: Totally 88 MCI-AD patients with syndrome of Xin(Heart) and Shen(Kidney) deficiency were assigned to the experimental group(47 cases, treated with TXR) and the control group(41 cases, treated with donepezil hydrochloride) using a random number table. Final recruited qualified patients were 44 cases in the experimental group and 39 cases in the control group. The therapeutic course was 12 weeks. Neuropsychological scales [mini mental state examination(MMSE) and Montreal cognitive assessment(MoCA)], and Chinese medicine(CM) dementia syndromes scales were performed in all patients, and results were compared between groups or intra-group before and after treatment. Results: MMSE and Mo CA scores of the two groups were increased after treatment compared with those before treatment(P0.05). But there was no statistical difference in MMSE or MOCA scores after treatment between the two groups(P0.05). CM dementia syndrome score was significantly decreased after treatment in the experimental group compared with the control group(P0.01). Visual spatial and executive function scores and delayed recall scores of the two groups were increased compared with those before treatment(P0.01). Conclusion: TXR could effectively improve cognitive impairment of MCI-AD patients with syndrome of Xin and Shen deficiency.     

Clinical Analysis for the Acupuncture Treatment in 42 Cases of GoutyRenal Damage

Objective: To observe the therapeutic effects of acupuncture on gouty renal damage. Method: 72 cases of gouty renal damage were randomly divided into a treatment group of 42 cases and a control group of 30 cases to observe the therapeutic effects and the changes in 24-hour urinary protein content, blood creatinine, uric acid and urea nitrogen in blood before treatment and one month after treatment. Results:The total effective rate in the treatment group reached 95.24%, which was remarkably higher than 63.33% in the control group. After one month of treatment, the indexes were found reduced in both groups, but the reduction rate in the treatment group was obviously superior to that in the control group.Conclusion: The patients with repeated attacks of gout may have a higher possibility to suffer from renal damage. Therefore, attention should be paid to its early diagnosis and treatment. Acupuncture may exert good therapeutic effects on early gout complicated with renal damage by adjusting the metabolism and improving the renal function.     

The Therapeutic Effects of Ling Gui Zhu Gan Tang Mixture in 50 Psychotic Patients with Obesity Induced by the Psychoactive Drugs

In order to observe the therapeutic effects of Ling Gui Zhu Gan Tang Mixture (芩桂术甘汤) on obesity induced by psychoactive drugs, 100 psychotics with obesity induced by psychoactive drugs were randomly divided into a treatment group (50 cases)and a control group (50 cases) for a 8-week treatment.The changes were determined by means of the Brief Psychiatric Rating Scale (BPRS) and the Treatment Emergent Symptom Scale (TESS) with the body weight recorded before and after treatment. The results showed that the total effective rate was 72% in the treatment group, and 14% in the control group,with the former obviously superior to the latter (P＜0.01). The BPRS scores were 33.02t7.34 in the treatment group and 32.39± 3.51 in the control group before treatment; and 20.38±5.10 in the treatment group and 20.82± 1.75 in the control group after treatment. The BPRS scores were obviously reduced after treatment in the two groups (both P＜0.01), but with no significant difference between the two groups (P＞0.05). This indicates that the Ling Gui Zhu Gan Tang Mixture does not influence the curative effect of the psychoactive drugs while showing the body weight-reducing effect. Therefore, the Ling Gui Zhu Gan Tang Mixture can be used for those psychotic patients with obesity induced by the psychoactive drugs (the incidence is 10-25%) in their continuous course of treatment with the latter drugs.     

TCM Treatment for 63 Cases of Senile Dyssomnia

In order to study the therapeutic effects of the TCM drugs on senile dyssomnia, 121 such patients were randomly divided into a treatment group of 63 cases (given the TCM drugs) and a control group of 58 cases (given estazolam). The changes shown in the SDRS and HAMA scores and the other indexes were observed in both of the two groups to evaluate the therapeutic effects. The results showed that the effective rate was 76.3% in the treatment group, and it was 69.1% in the control group; and that the TCM drugs had better effects in improving such symptoms as lethargy, dry mouth, and rebound of insomnia. Therefore, it can be concluded that the effect of the TCM drugs is better for senile dyssomnia than that of the Western drug estazolam.     

Clinical Efficacy of Traditional Chinese Medicine on Acute Myocardial Infarction——A Prospective Cohort Study

<正>Objective:To evaluate the clinical effects of Chinese medicine(CM) on acute myocardial infarction (AMI) with a prospective cohort study.Methods:A total of 334 AMI patients from January 2007 to March 2009 were consecutively enrolled,and were assigned to a treatment group(169 cases) treated with combined therapy(CM for at least one month and Western medicine) and a control group(165 cases) with Western medicine alone.Clinical data including age,gender,smoking,medical history,infarction area,heart functional classification,CM syndrome scores,blood-stasis syndrome score,primary end-point(death,nonfatal myocardial infarction,and revascularization) and secondary end-point(ischemic stroke,rehospitalization due to angina,heart failure and shock),were collected. CM syndrome scores,blood-stasis syndrome score,primary end-point and secondary end-point were collected during the 6-month follow-up.Kaplan-Meier method was used for the survival analysis.The multifactor analysis was analyzed by Cox proportional hazards regression.Results:At the end of 6-month the CM syndrome score and blood- stasis syndrome score in the treatment group were lower than those in the control group(P0.01),especially the symptoms of chest pain,spontaneous perspiration and insomnia.Rehospitalization rate due to angina during the 6-month follow-up in the treatment group(2.96%) was lower than that in the control group(7.88%,P0.05).Kaplan- Meier survival curve showed that event-free cumulated survival of rehospitalization due to angina during the 6-month follow-up in the treatment group was higher than that in the control group(Log rank 4.700,P=0.03).Cox regression analysis showed that heart dysfunction[hazard ratio(HR)=1.601,95%CI=1.084-2.364,P=0.018]and diabetes mellitus(HR=1.755,95%Cl=1.031-2.989,P=0.038) were hazard factors to end-point,whereas CM(HR 0.405,95% Cl=0.231-0.712,P=0.002),percutaneous coronary intervention(PCI,HR=0.352,95%CI=0.204-0.607,P0.001) and angiotensin converting enzyme(ACE) inhibitors(HR=0.541,95%Cl=0.313-0.936,P=0.028) were protective factors.Conclusions:CM therapy could decrease CM syndrome scores and blood-stasis syndrome score,reduce the rehospitalization rate during 6-month follow-up due to angina.Heart dysfunction and diabetes mellitus were hazard factors to end-point,whereas CM,PCI and ACE inhibitors were protective factors.     

Thirty Cases of Obsession Treated by Point-Stimulation and with Small Dose of Chlorimipramine

Objective: To investigate the clinical therapeutic effects of point-stimulation for obsession. Methods: Sixty cases of obsession were divided into two groups: a control group of 30 cases treated with chlorimipramine (Ch1), and a treatment group of 30 cases treated by point-stimulation (PS) plus chlorimipramine (PS Chl). The therapeutic effects and side-effect were evaluated according to the criteria set in Yale-Brown Obsession Scale (Y-BOCS), Hamilton's depression scale (HAMD), brief psychiatric rating scale (BPRS) and treatment emergent symptom scale (TESS). Results: The cure rate and markedly effective rate were respectively 26.7% and 56.6% in the control group, and 43.3% and 50% in the treatment group, suggesting that the therapeutic effect in the treatment group was better than that in the control group. The incidence of adverse side-effects was 73.33% in the control group and 46.67% in the treatment group, with a significant difference between the two groups (P<0.05). Conclusion: Point-stimulation plus small dose of chlorimipramine was superior to the simple chlorimipramine treatment, indicating that the combined method was more effective and safe for obsession with less side effects.     

子午流注结合五行音乐疗法治疗心脾两虚型失眠的临床效果观察

  目的  观察子午流注结合五行音乐疗法治疗心脾两虚型失眠的临床疗效。  方法  选取浙江省立同德医院2019年6月—2020年6月收治的心脾两虚型失眠患者72例,根据随机数字表法随机分为观察组和对照组,每组36例。对照组仅采用五行音乐干预,观察组给予子午流注结合五行音乐干预方法。比较2组患者治疗前后匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)量表的各项评分和相关心脾两虚型失眠的中医证候评分,并比较2组患者的临床疗效。  结果  治疗前,2组在主观睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、日间功能、安眠药物及PSQI总分等评分方面比较差异无统计学意义(均P>0.05);治疗后,2组患者上述指标均有所改善,观察组患者在睡眠质量各方面评分和PSQI总分均明显低于对照组患者(均P < 0.01)。治疗前,2组中医证候评分差异无统计学意义(t=0.191,P>0.05);治疗后,2组中医证候评分均有所改善,观察组较对照组明显降低(t=26.886, P < 0.01)。观察组临床治疗总有效率显著高于对照组(χ2=8.692,P < 0.01)。  结论  子午流注结合五行音乐疗法能明显改善心脾两虚型失眠患者的临床症状,提高临床治疗效果,值得在临床上推广和使用。      

头皮针治疗恶性肿瘤患者化疗后心脾两虚型失眠临床观察

目的:观察头皮针治疗恶性肿瘤患者化疗后心脾两虚型失眠的临床疗效及治疗依从性,为其临床应用提供依据。方法:将80例恶性肿瘤化疗后心脾两虚型失眠患者,按照随机数字表法分为观察组和对照组各40例,对照组每天睡前30 min口服地西泮片5 mg,观察组选取百会、囟会等穴行头皮针治疗(浅刺,每次留针时间40 min,期间行针3次),两组均连续治疗3周。分别于治疗前后测定两组匹兹堡睡眠质量指数(PSQI)量表评分、阿森斯失眠量表(AIS)评分及美国东部肿瘤协作组(ECOG)体能状态评分(ZPS法),并根据两组失眠症状、睡眠深度、睡眠时间、晚间睡眠时间等指标变化判定临床疗效;同时观察两组治疗依从性。结果:治疗后两组PSQI、AIS和ZPS评分均较治疗前下降,且观察组PSQI、AIS和ZPS评分均低于对照组,差异有统计学意义(P<0.05);观察组和对照组总有效率分别为90.0%、67.5%,差异有统计学意义(χ2=6.050,P<0.05);观察组和对照组治疗依从率分别为95.0%、80.0%,差异有统计学意义(χ2=4.75,P<0.05)。结论:头皮针治疗恶性肿瘤患者化疗后心脾两虚型失眠临床总有效率高,且患者治疗依从性好。     

综合心理疗法治疗失眠症临床疗效分析

目的:评估综合心理疗法治疗失眠症的临床疗效。方法:将70例门诊失眠症患者随机分为2组进行治疗,每组各35例。综合心理治疗组（综合组）接受综合性心理治疗,渐进式放松组（放松组）接受渐进式放松治疗。用匹兹堡睡眠质量指数（PSQI）量表评估患者的睡眠变化情况,同时用焦虑自评量表（SAS）、抑郁自评量表（SDS）评估患者情绪的变化情况。结果:治疗后两组患者的PSQI、SAS、SDS评分均显著减低（P<0.01）。1个月后随访,疗效稳定。综合组治疗后的PSQI评分显著低于放松组（P<0.01）。PSQI评分减分率>50％,综合组需治疗2周,放松组需3周。结论:综合心理疗法和渐进式放松疗法对失眠症患者都具有明显的、稳定的疗效;综合心理疗法的疗效优于渐进式放松法,并且起效更快。     

调督安神针刺治疗心脾两虚型失眠的临床疗效评价

【目的】观察调督安神针刺法结合药物艾司唑仑治疗心脾两虚型失眠的临床疗效。【方法】将70例心脾两虚型原发性失眠患者随机分为治疗组和对照组各35例。对照组给予睡前口服艾司唑仑片治疗,连续治疗6周;治疗组在对照组口服药物的基础上给予调督安神针刺治疗,取穴百会、印堂、神庭、安眠、神门、三阴交等,每周3次,连续治疗6周。分别在治疗前、治疗3周、治疗6周,以及治疗结束后1个月随访,采用匹兹堡睡眠质量指数(PSQI)、Epworth思睡量表、阿森斯失眠量表(AIS)对患者的睡眠情况进行评估。【结果】(1)脱落情况:治疗组有5例、对照组有3例患者不能按照规定如期进行治疗而脱落,最终治疗组30例、对照组32例患者完成试验。(2)疗效情况:治疗组总有效率为90.0%,优于对照组的71.9%,差异有统计学意义(P0.01)。(3)治疗3周、治疗6周及治疗结束后1个月随访时,治疗组在降低PSQI、Epworth和AIS量表评分方面均优于对照组,差异均有统计学意义(P0.05或P0.01)。【结论】调督安神针刺法结合药物艾司唑仑治疗心脾两虚型原发性失眠的疗效确切,其疗效明显优于单纯药物治疗。     

安眠贴治疗肝郁脾虚型慢性失眠的临床价值研究

目的：探讨安眠贴治疗肝郁脾虚型慢性失眠的临床疗效。方法将我院2015年6月至2016年1月收治的80例肝郁脾虚型慢性失眠患者按照数字表法随机分为治疗组和对照组,每组40例,分别辅以安眠贴治疗和常规药物治疗,比较2组临床治疗效果。结果治疗组患者治疗后PSQI评分、睡眠率和生活质量评分分别为（8．1±2．6）分、（79．2±10．2）％、（62．5±5．2）分,对照组患者治疗后PSQI评分、睡眠率和生活质量评分分别为（9．7±2．4）分、（67．5±10．3）％、（51．2±4．7）分,2组比较差异均有统计学意义（P＜0．05）。治疗组治愈率（60．0％）和治疗总有效率（90．0％）均高于对照组（30．0％、77．5％）,复发率（10．0％）低于对照组（22．5％）,2组比较差异均有统计学意义（P＜0．05）。结论在常规药物治疗基础上辅以安眠贴治疗肝郁脾虚型慢性失眠,可进一步提高临床疗效,降低复发率,更好地改善患者睡眠质量和生活质量。     

解郁安神汤治疗失眠的临床观察

[目的]对解郁安神汤治疗失眠的临床观察。[方法]治疗组35例给予中药解郁安神汤,对照组29例给予帕罗西汀片。[结果]治疗组痊愈8例,显效12例,有效12例,无效3例,总有效率91·43%;对照组痊愈6例,显效10例,有效11例,无效2例,总有效率93·10%。两组间比较的差异无显著性(P>0·05)。[结论]解郁安神汤具有镇静催眠作用,用于治疗失眠及伴有的抑郁焦虑状态疗效肯定。     

针刺治疗失眠焦虑抑郁状态30例

目的观察针刺对失眠焦虑抑郁状态的疗效。方法将60例失眠焦虑抑郁状态患者随机分为针刺组和对照组,每组30例,分别采用针刺和舒乐安定治疗,疗程4周。治疗前后分别对两组患者进行匹兹堡睡眠质量指数（Pittsburgh sleep quality index,PSQI）问卷、抑郁自评量表（self-rating depression scale,SDS）、焦虑自评量表（self—rating anxiety scale,SAS）评定。结果针刺组和对照组治疗前SDS、SAS评分显著高于国内常模（P〈0．05）;治疗后针刺组PSQI、SDS和SAS显著低于治疗前（P〈0．01）,对照组PSQI和SAS评分也显著低于治疗前（P〈0．01）,且针刺组SDS评分显著低于对照组（P〈0．01）。结论针刺对失眠及伴有的抑郁状态具有较好疗效,值得推广应用。     

耳穴金针联合扶正针法治疗阳虚质慢性疲劳综合征

目的:观察耳穴金针联合扶正针法干预阳虚质慢性疲劳综合征的临床疗效.方法:将90例阳虚质慢性疲劳综合征患者随机分为三组,每组各30例,治疗组采用耳穴金针联合扶正针法治疗,A对照组采用耳穴金针治疗,B对照组采用扶正针法治疗,每周1次,连续治疗8次,测定治疗前后疲劳量表-14(fatigue scale - 14,FS - ...     

内观认知疗法治疗大学生非器质性失眠症临床观察

目的:内观认知疗法治疗非器质性失眠症的疗效观察。方法:非器质性失眠症患者60例,随机分为研究组和对照组各30例,其中研究组采用内观认知疗法（NCT）干预,对照组保持与研究组相同时间的安静独处,治疗周期均为1周。于治疗前和治疗结束1月后对两组同时进行匹兹堡睡眠指数量表（PSQI）、焦虑自评量表（SAS）、自尊量表（SES）、自我和谐量表（SCCS）等心理量表评估,于治疗前和治疗结束后进行1月智能手环（SB）睡眠监测,比较各项指标治疗前后和组间差异。结果:研究组治疗前后PSQI总分、成分1（睡眠质量）、成分2（入睡时间)、成分4（睡眠效率）、成分7（日间功能障碍）有显著性差异（P<0.01）;研究组治疗前后SAS、SES、SCCS总分有统计学差异（P<0.01）;研究组SB监测结果治疗前后3项指标比较均有显著性差异（P<0.01）;对照组所有量表及SB监测结果治疗前后均无显著性差异（P>0.05）。结论:内观认知疗法对大学生非器质性失眠症有治疗作用。