共查询到20条相似文献，搜索用时 46 毫秒
1.
2.
3.
4.
5.
6.
7.
S. Mhalla R. Hammoud A. Frih Y. Kadri A. El Argoubi M. Elmay M. Mastouri 《Médecine et maladies infectieuses》2018,48(3):175-179
Objective
Hemodialysis patients are at increased risk of infection by hepatitis C and B viruses, which are significant causes of mortality and morbidity. Prevention of their transmission in hemodialysis units remains a challenge worldwide. We aimed to investigate the prevalence of these two infections and to explore major risk factors among patients on chronic hemodialysis.Materials and methods
We performed a cross-sectional study of 109 hemodialysis patients (mean duration of hemodialysis of seven years) between 2012 and 2014 in a Teaching Hospital of Monastir, Tunisia. Hepatitis B and C serological markers were searched for using a chemiluminescent assay. Genome detection was performed using a commercially available quantitative real-time PCR test.Results
A total of 109 hemodialysis patients were enrolled (75 males and 34 females). Ages ranged from 21 to 81 years. Six (5.5%) of these 109 patients had HBV infection defined by a positive HBsAg in four (3.7%) patients and by a detectable DNA associated with an “isolated anti-HBc” profile in the remaining two patients. Hepatitis C was observed in eight patients (7.3%) and five of them had detectable RNA. Hemodialysis duration ? 5 years was the main risk factor for hepatitis C infection (P = 0.01; OR: 3.11; 95% CI [1.57–13.71]).Conclusion
Our findings confirm the downward trend of the prevalence of both hepatitis B and C infections among Tunisian hemodialysis patients. Hemodialysis duration remains the main risk factor for hepatitis C infection. Occult hepatitis B infection should be suspected and investigated, especially among patients with an “isolated anti-HBc” profile. 相似文献8.
9.
10.
11.
12.
13.
14.
15.
16.
17.
18.
19.
20.
J.M. Bohbot A. Goubard F. Aubin Y. Mas E. Coatantiec N. Lucas F. Verrière 《Médecine et maladies infectieuses》2019,49(3):194-201