发挥医务人员作用 搞好医德医风建设

1 努力提高医务人员的职业道德素质,是搞好医德医风建设的关键所在医院职工道德水准的高低不仅关系医院本身的生存和发展,影响医院的改革和稳定,同时也直接影响党和政府在人民群众中的声誉.基于这种认识,多年来,我院在医德医风工作中,始终把提高医务人员的政治业务素质作为工作的着眼点,根据医务人员的特点,坚持进行以人为本的思想政治工作,反复教育医务人员树立职业理想、讲究职业道德、提高职业技能、严守职业纪律.我们主要采取教育、启发、引导、熏陶和激励等形式和方法来培养和激发医务人员救死扶伤的责任感,对技术精益求精的事业心和全心全意为人民服务的职业精神.     

新形势下如何做好急救中心的思想政治工作

"120"院前急救工作事关人民群众的身体健康,做好职工的思想政治工作,树立全心全意为病人服务的思想,对保障人民健康、构建和谐社会具有十分重要的意义。坚持以正面教育为主,以理服人、言传身教、寓教于乐等是新形势下加强急救中心思想政治工作的有效方法。     

新形势下如何做好急救中心的思想政治工作

“120”院前急救工作事关人民群众的身体健康，做好职工的思想政治工作，树立全心全意为病人服务的思想，对保障人民健康、构建和谐社会具有十分重要的意义。坚持以正面教育为主，以理服人、言传身教、寓教于乐等是新形势下加强急救中心思想政治工作的有效方法。     

对医院精神文明建设的思考

1必须充分认识医院加强精神文明建设的重要性社会主义医疗卫生事业的性质是社会公益性与福利性的统一,决定了在市场经济条件下,仍然必须坚持全心全意为人民服务的宗旨,市场竞争越激烈,就越要抓好医院的精神文明建设。1.1搞好医院的精神文明建设,通过生动有效的思想政治工作和以医德医风建设为主要内容的职业道德教育,激发全院医务人员的主人翁意识和齐心协力建设医院、发展医院的主观能动性。克服困难,开拓前进,在全社会树立良好的形象,在竞争中立于不败之地。1.2为人民健康服务,为现代化建设服务,这是新时期医疗工作的根本宗旨和办院方向,…     

论医院思想政治工作对医院发展的重要核心意义探究和实践

就当前市场经济体制而言,医院思想政治工作的首要任务就是用科学发展观来统领全局,提高医务人员对世界的认知能力,做到为人民服务、奉献社会的目标,促进医院健康发展。本文先就医院思想政治工作的内容进行了简单的阐述,而后就医院思想政治工作的意义进行了深入的分析,并提出了加强党组织对思想政治工作的领导、以全方位目标管理为总纲、等加强医院思想政治工作实践措施。     

浅析医院文化建设与思想政治工作

医院文化的建设是以人为本,以调动职工积极性为目标,是运用文化的力量和方式对医院进行管理的一种管理形式.健康的医院文化对医务人员的群体意识起导向、激励、凝聚和规范作用,可为医院管理注入新的活力.而思想政治工作是保证医院的办院方向不偏离为人民服务,为经济建设服务的宗旨,保证医院朝着社会主义方向健康发展.二者相互渗透,优势互补,同属上层建筑.探索医院文化建设与思想政治工作对于加强医院精神文明建设,实现社会与经济两个效益的最佳结合,推动医院的改革与发展具有十分重要的现实意义.     

浅谈新时期高校后勤系统的思想政治工作

高校后勤工作担负着为师生生活提供服务，为教学和科研提供后勤保障的重任[1]。加强后勤职工的思想政治工作，为学校的教学、科研和学生的生活提供高质量的服务，具有重要意义。目前，高校后勤系统职工普遍存在文化程度较低、理论素质不高、年龄结构失衡及保障感不高等问题。新时期，新形势，对后勤职工进行思想政治教育，应坚持关爱职工、尊重职工，通过活动凝聚职工，坚持促进职工的发展，依照科学的管理制度规范职工。     

浅谈医院思想政治工作的重要性与方法

思想工作是教育人、改造人、塑造人灵魂的一个系统工程,是我党搞好各项工作的思想保证。当前随着社会主义市场经济的确立与发展,医药卫生体制改革的深化,医院的改革与发展正处于攻坚阶段,而要保证医院改革和发展的顺利进行,医院的思想政治工作就必须适用形势的发展,按照江总书记在全国思想政治工作会议和全国宣传部长会议的讲话精神,大力加强医院的思想政治工作,通过加强社会主义精神文明建设和职业道德建设,培养医术精、医德好的医务人员队伍,树立“白衣天使”的良好的社会形象,以满足人民群众日益增长的医疗健康需求。1做好医院思想政治工…     

谈晓之以理过程中的动之以情

在当今医疗卫生事业不断向现代化发展的新形势下,医务人员的思想政治工作的目的是实现医疗卫生工作改革方针贯彻落实,增强为人民群众的身体健康服务的意识,提高人口素质为目标,充分调动医务人员的积极性、主动性、创造性,增强主人翁责任感,走科技之路,勇攀科学高峰,切实为社会主义现代化建设培养“四有”的专业人才。晓之以理,动之以情作为达到思想政治工作目的的一种方法,政工人员要怎样掌握这种方法,做好医务人员的思想政治工作,本人从事政工工作中的体会就晓之以理的过程中如何动之以情谈点肤浅的认识。1确立为医务人员服务的理念,尊重和…     

新时期应加深对全心全意为人民健康服务的认识

近几年来 ,有一部分医务人员和医学生对社会主义医德的核心 ,即全心全意为人民健康服务有所动摇。他们认为在市场经济条件下要讲求医院利益和个人利益 ,全心全意为人民健康服务不现实。这样势必会影响整个医疗卫生行业的医德医风建设和以德治国方略的实施。笔者认为在新时期要使广大医务人员和医学生牢固树立全心全意为人民健康服务的思想 ,必须加深对这一思想的认识。1　全心全意为人民健康服务是医疗卫生工作的根本宗旨　　人民群众是社会物质财富和精神财富的创造者 ,是推动历史前进的根本力量 ,医务人员应当在职业生活中全心全意为他们…     

益智健脑颗粒联合针灸对阿尔茨海默病大鼠学习记忆的影响

目的观察益智健脑颗粒联合针灸对阿尔茨海默病（Alzheimers disease,AD）大鼠学习记忆的影响。方法将大鼠随机分为假手术组（A组）、模型组（B组）、针灸组（C组）、益智＋针灸组（D组）各10只,B、C、D 3组分别以海马CA1区注射β淀粉样蛋白25-35（Aβ25-35）造模,A组注射等量的双蒸水,各组分别治疗20 d后行Morris水迷宫试验,观察大鼠学习记忆能力变化。结果B组较A组的平均潜伏期明显延长,差异具有统计学意义（P〈0.05）;与B组比较,C组、D组的平均潜伏期明显缩短,过台次数增多,差异具有统计学意义（P〈0.05,P〈0.01）;与C组比较,D组的潜伏期缩短,过台次数增多,差异具有统计学意义（P〈0.05）。结论益智健脑颗粒联合针灸能够提高Aβ25-35介导的AD模型大鼠的学习记忆能力。     

Liuwei Dihuang,a traditional Chinese herbal formula,suppresses chronic inflammation and oxidative stress in obese rats

OBJECTIVE： To investigate the anti-inflammatory, anti-oxidative stress, and adipokine-ameliorating effects of Liuwei Dihuang （LWDH）, a traditional Chinese herbal formula, in obese rats. METHODS： After 2 weeks of acclimation with free access to regular rodent chow and water, obese-prone-caesarean-derived （OP-CD） rats were fed a modified AIN-93G diet containing 60% energy from fat. Treatment was performed twice daily by gavage feeding with 500, 1 500, or 3 500 mg/kg body weight LWDH suspended in water （n=12 rats per group）. Twelve obese-resistant-CD （OR-CD） rats were fed the atherogenic diet and gavaged with water, and served as the normal control. Blood biomarkers of inflammation, oxidative stress and adiponectin were measured post-sacrifice and used to determine the treatment effect of LWDH and assess the suitability of OR/OP-CD rats for studying these parameters. RESULTS： After 9 weeks of treatment, LWDH lowered serum C-reactive protein （CRP） and tumour necrosis factor-α （TNF-α） levels. Serum interleukin-6 （IL-6） levels showed a tendency towards reduction, but were not significantly different from the OP-CD control. Liver superoxide dismutase （SOD） activity was increased in response to all three doses of LWDH, while the levels of reduced （GSH） and oxidized glutathione （GSSG） and thiobarbituric acid reactive substances （TBARS） were unchanged. Serum adiponectin levels were increased in response to oral administration of LWDH at the dose of either 500 or 1 500 mg/kg body weight. In addition, comparisons between OR-CD and OP-CD rats revealed differential, and for some biomarkers, conflicting characteristics of high-fat diet-fed OP-CD rats in reference to obese human subjects in terms of inflammatory and oxidative stress biomarkers and circulating adiponectin levels. CONCLUSION： The results show, for the first time, the anti-inflammatory, anti-oxidative stress and adiponectin-ameliorating effects of LWDH in obese rats. The suitability of the OP-JOP-CD rat model as     

程丑夫教授论治情志病验案举隅

程丑夫是国家级名老中医,湖南中医药大学第一附属医院主任医师、教授、博士生导师,享受政府特殊津贴专家,出身于中医世家,从医40余年,经验丰富,对于内科系统及疑难杂症的治疗颇有心得,笔者有幸跟师学习,聆听教诲,受益匪浅,现将程师论治情志病的经典验案略陈一二。1思虑伤脾案患者肖某,女,27岁。初诊：2014年5月20日。半年前因婚变后出现忧心忡忡,多思多虑,近1月来反复腹部胀满,刻诊：腹胀,食后为甚,呃逆,无反酸,通气后可减轻,无腹痛,不欲食,夜寐不安,二便调。舌红苔厚白腻,脉弦,BP：110／70mmHg。     

表皮生长因子受体酪氨酸激酶抑制剂在非小细胞肺癌应用的瓶颈——获得性耐药

以表皮生长因子受体酪氨酸激酶抑制剂（epidermal growth factor receptor-tyrosine kinase inhibitor,EGFR-TKI）分子靶向治疗研究为肇始,转化性研究使基础实验和临床实践间的鸿沟迅速填平,改变着人们认识治疗肺癌的视角。无可否认,EGFR-TKI上市后极大地延伸了肿瘤学家治疗肺癌的手段,但不管从临床经验、临床研究数据、分子生物学层面还是文献计量学的角度,     

补肾活血方对PCOS大鼠模型卵巢中PAI-1mRNA表达的影响

目的探讨补肾活血方对大鼠PCOS模型卵巢局部纤溶酶原激活物抑制因子-1（PAI—1mRNA）表达的影响。方法选用未成年24d龄SD雌性大鼠60只,随机分为模型组、克罗米酚组、补肾活血方高剂量组、补肾活血方低剂量组、正常对照组5组。用Bogovich法建立大鼠多囊卵巢病理模型。以克罗米酚为对照。用原位杂交法观察补肾活血方对多囊卵巢大鼠局部PAI—1mRNA的影响。结果模型组卵巢局部PAI—1mRNA存在卵泡膜间质细胞显著增高,用补肾活血方高、低剂量与克罗米酚药后,卵巢局部PAI-1mRNA的表达明显降低．差异具有统计学意义（P〈0．05、P〈0．01）。补肾活血方高剂量组与克罗米酚组比较,差异具有显著统计学意义（P〈0．01）;低荆量组与克罗米酚组比较差异无统计学意义（P〉0．05）,补肾活血方高、低剂量组比较,低剂量组卵泡膜间质细胞上PAI-1的基因表达增高更明显,但二者差异无统计学意义（P〉0．05）。结论PAI-1mRNA可能与多囊卵巢综合征的发病机制有关。以补肾活血立法的补肾活血方能降低多囊卵巢大鼠局部PAI—1mRNA的显著增高表达．降低PAI—1mRNA卵巢局部的作用。提示补肾活血方可能通过PAI—1mRNA途径促进卵巢排卵的机制。     

UniPron is A Fully Effective Non-hormonal Reversible Contraceptive in Baboon Model （Papio Anubis）

Objective To determine the safety and efficacy of UniPron as a reversible contraceptive.
Methods Vaginal swabs were obtained before and after UniPron administration, cultured onto appropriate culture media and bacteria identification was done based on type of media used, Gram stain reactions, colony morphology and biochemical tests. Vaginal biopsy tissues were processed using paraffin wax method, stained with hematoxylin and eosin and examined under light microscopy to determine the effect of the product on vaginal tissues. The effect of UniPron on sperm was examined by mixing the product with electroejaculated spermatozoa in vitro at different concentrations. For efficacy studies, male baboons of proven fertility were mated with UniPron treated or untreated females of proven fertility during the fertile stages.
Results All the five females （100%） that were treated with UniPron did not conceive and they regained total fertility when the treatment was stopped while all the controls conceived. At a concentration of 40%, UniPron completely immobilized spermatozoa in an in-vitro system. UniPron mechanism of action was by lowering the vaginal pH and on application in baboon, the pH was lowered for at least 3 h after which it went back to normal.
Conclusions As we plan for a study to test UniPron as a microbicide to prevent STIs including HIV, our current study has established that this novel product is effective in contraception and harmless to vaginal tissues and vaginal microbial flora in a baboon model （Papio anubis）.     

WHO西太区与“世界中医药学会联合会”中医名词术语国际标准比较研究：精、神、气、血、津、液部分

精、神、气、血、津、液是中医理论中6个非常重要的概念，有关术语在《WHO西太区传统医学国际标准名词术语》中一共收录了59条，“世界中医药学会联合会”（以下简称世中联）《中医基本名词术语中英对照国际标准》中收录了58条。血、津、液的内涵较为具体，有一定的物质基础，理解并不困难。翻译上虽有差异，但亦不难统一。精、神、     

Mechanical tests on the reconstructed anterior cruciate ligament fixed with allogenetic cortical bone cross-pin on the femoral side

Background Anterior cruciate ligament reconstruction （ACLR） has developed dramatically in the last century.Now,ACLR has become a reliable and productive procedure.Patients feel satisfied in 〉90% cases.The aim of this study was to evaluate the feasibility of allogenetic cortical bone cross-pin （ACBCP） used as a clinical fixation method in anterior cruciate ligament reconstruction on the femoral side based on biomechanical tests in vitro.Methods The specimens were provided by the bone banks of the First Affiliated Hospital of People＇s Liberation Army of General Hospital from September 2011 to June 2012.Fresh deep frozen human allogenetic cortical bone was machined into cross-pins which is 4.0 mm in diameter and 75.0 mm in length.Biomechanical parameters compared with Rigidfix were collected while cross-pins were tested in double-shear test.The load-to-failure test and cycling test were carried out in a goat model to reconstruct anterior cruciate ligament with Achilles tendon autograft on the femoral side fixed by human 4.0 mm ACBCP and 3.3 mm Rigidfix served as control.Maximum failure load,yield load,and stiffness of fixation in single load-to-failure test were compared between the two groups.Cycle-specific stiffness and displacement at cycles 1,30,200,400,and 1 000 were also compared in between.Results In double-shear test both maximum failed load and yield load of 4.0 mm humanACBCP were （1 236.998±201.940） N.Maximum failed load and yield load of Rigidfix were （807.929±110.511） N and （592.483±58.821） N.The differences of maximum failed load and yield load were significant between ACBCP and Rigidfix,P 〈0.05.The shear strength of ACBCP and Rigidfix were （49.243±8.039） MPa and （34.637±3.439） MPa,respectively,P 〈0.05.In the load-to-failure test ex vivo,yield load and maximum failed load of ACBCP fixation complexity （（867.104±132.856）N,（1 032.243±196.281） N） were higher than those of Rigidfix （（640.935±42.836） N,（800.568±64.890） N,P 〈0.05）.However,s     

中医疗法治疗运动性疲劳的研究进展

随着竞技体育的发展，运动员经常承受着大负荷、超强度的体力训练，因此极易产生运动性疲劳。疲劳的出现使肌内压增高，局部缺血，造成氧化代谢、H^＋排出率与pH值降低，血乳酸增高，从而影响肌纤维神经传导速度和肌内收缩力量，减弱了肌肉保护能力。致使较多的冲击力传到骨骼上，故易导致疲劳骨折的发生,严重影响了运动员的训练和比赛成绩，对运动员身心产生不必要的伤害。运动性疲劳消除手段的研究一直是竞技体育工作和运动医学关注和研究的焦点。     

Effects of tacrolimus and cyclosporine treatment on metabolic syndrome and cardiovascular risk factors after renal transplantation: a meta-analysis

Background The therapeutic success of renal transplantation has been largely attributable to the development of effective and balanced immunosuppressive treatment regimens.This study provides a meta-analysis of a series of randomized controlled trials that compared the effects of tacrolimus and cyclosporine on metabolic syndrome （MetS） and cardiovascular risk factors after renal transplantation.Methods We searched various electronic databases and bibliographies,including MEDLINE,the Cochrane Central Register of Controlled Trials,and EMBASE,for relevant studies published prior to October 2012.Results Our meta-analysis included five randomized controlled trials that examined a total of 923 patients.The tacrolimus group and the cyclosporine group exhibited no significant differences in MetS incidence after renal transplantation; risk ratio （RR）：1.06,95％ confidence interval （C/）：0.73-1.55,P=0.76.Cyclosporine treatment was associated with a higher incidence of hyperlipidemia （RR：0.50,95％ CI：0.39-0.64,P ＜0.01）.Although there were no statistically significant differences,cyclosporine treatment was associated with a higher incidence of hypertension （RR：0.91,95％ CI：0.83-1.00,P=0.06） after renal transplantation compared to tacrolimus treatment,and tacrolimus treatment was associated with a higher incidence of diabetes after renal transplantation （RR：1.79,95％ CI：0.98-3.27,P=0.06） compared to cyclosporine treatment.Conclusions Compared to tacrolimus treatment,cyclosporine treatment was associated with a higher incidence of hyperlipidemia.Future large-scale studies are expected to be conducted to further confirm our findings.