573名维吾尔族女性青少年身高、体重与性征发育的关系

目的：了解维吾尔族女性青少年身高、体重与性征发育的关系，为制定青春期保健、性征发育教育计划及临床诊断和预防性征发育异常提供理论依据。方法：随机选取573名乌鲁木齐地区维吾尔族8～15岁女性青少年，对其身高、体重、体重指数(BMI)、乳房发育程度、月经初潮、阴毛和腋毛发育进行测量和观察。结果：维吾尔族女性身高速度高峰(PHV)出现在10岁组，快速生长期年龄为10～13岁，体重速度高峰(PWV)和BMI高峰均出现在13岁组。乳房开始发育的高峰出现在ll岁组，阴毛和腋毛开始生长的年龄平均为13岁，月经初潮年龄平均为13．46岁。对乳房、阴腋毛生长发育的影响大小依次为体重、身高、BMI，对月经初潮的影响大小依次为体重、BMI、身高。结论：通过干扰体重可预防女性性征异常发育，乳房开始发育时保持稳定的BMI能使月经正常初潮。     

正常青少年青春期性征发育调查

目的：了解正常青少年青春期性征发育的状况与规律。方法：男性测量睾丸容积,阴茎长度和直径并分期,观察阴毛、腋毛、胡须并分期。观察有无喉结,询问首次遗精时间。女性检查乳房、阴毛、腋毛、大阴唇并分期,询问月经初潮时间,根据性征分期计算性发育指数并评定总性发育程度。结果：制定了睾丸容积、阴茎长度和直径的正常范围,女性乳房、阴毛Ｔａｎｎｅｒ分期的年龄分布状况,男、女总性发育程度随年龄增长而增加的趋势。月经初     

儿童性早熟的分类与治疗

女孩在8岁之前出现乳房增大、阴毛、腋毛生长等任何一项或多项第二性征，或月经初潮于10岁以前；男孩在9岁之前出现阴茎、睾丸增大、阴毛生长等性发育表现者即为性早熟。     

1231名立陶宛在校女生青春期前乳房和阴毛发育的开始时间

背景:由于内分泌系统中不同的腺体影响着乳房、阴毛和腋毛的发育,因此,为区别不同的病理状态,有必要对青春期进行正确分期。目的:确定立陶宛在校女生青春期前肾上腺皮质功能初现及乳房发育的常见时间。方法:对1231名年龄7.0～11.6岁间的在校女生进行横断面研究。根据Tanner方法,将青春期分期。根据概率分析计算进入青春期各个时期的平均年龄。结果:255例7岁女生中,2例(0.8%)表现为肾上腺皮质功能初现过早,1例(0.4%)表现为乳房发育过早。出现阴毛/腋毛的平均年龄为11.0岁。2期、3期和4期乳房发育的平均年龄则分别为10.2岁、11.3岁和13.9岁。…     

南通市区青少年学生性发育现状调查*

目的：了解南通市区青少年学生性发育情况。方法：采用横断面的方法,对南通市7 852例青少年进行常规体质和性发育检查,观察身高,体重,男性阴毛、腋毛分期,测定阴茎长度、直径、睾丸容积,女性乳房Tanner分期等。结果：南通市初中学生的身高及体重随年龄的增长而增加,男性首次遗精的中位年龄为14.5岁,女性月经初潮的中位年龄为13.5岁。结论：南通市区男性青少年首次遗精与女性月经初潮的年龄均有所提前。     

第96例闭经-声音变粗-乳腺发育

病历摘要 患者,16岁,社会性别为女性.因月经初潮未来于2005年7月19日入院.患者自幼以女孩身份抚养,身高增长速度与同龄人无异,但力气强于同龄.5年前开始出现乳腺发育及腋毛阴毛生长,3年前开始出现声音嘶哑,变粗,1年前出现喉结突出.     

表现为性早熟、偏瘫的基底节区生殖细胞瘤1例

患儿男,8岁,因第二性征提前发育1年,右侧肢体无力3个月入院。患1年前开始出现阴毛、腋毛生长,阴茎长大、勃起,无遗精,声音变粗。近3个月来自觉右侧肢体无力,伴间歇性头痛,无恶心、呕吐,无肢体抽搐。既往体健,足月出生。查体：语言流利。喉结生长,声音粗,阴毛、腋毛浓密,阴茎粗大。右侧鼻     

垂体柄中断综合征1例

垂体柄中断综合征(pituitary stall interruption syndrome,PSIS)相当罕见,作者发现1例,现报道如下. 1 临床资料 患者,男,27岁,因生长发育迟缓伴性不发育15年,于2008年10月24日入院.15年前开始发现患者生长迟缓伴性器官不发育,未长腋毛、阴毛.起病以来无多尿,有点怕冷.患者父母非近亲结婚,分娩臀先露难产,其妹妹发育正常.患者智力尚可,学习成绩中下,无外伤史.入院检查:身高150.5 cm,体质量39 kg,BP 90/60 mm Hg.体型较消瘦,颜面轻度浮肿,唇无胡须,无喉结.甲状腺不大,心肺(-),腹软,肝脾(-).外生殖器幼稚型,双侧睾丸细小,无阴毛、腋毛.     

只有阴毛而没有其他性征的婴儿

本研究对9例只有阴毛而无其他性征男婴进行评估。阴毛发育的年龄中值为4.5个月,有明显表现的年龄中值为7.5个月。其中6例患儿的内分泌学调查结果正常。平均年龄为12个月时阴毛开始消退,表明该表现是良性。9岁以下男性阴毛发育被认为是早熟,表明可能为病理状态(也就是说性早熟、     

成人高促性腺激素性性功能低减病1例

1 病例介绍 患者,男,37岁,双乳增大20余年,婚后不育10年.2005年3月1日入院.患者诉自13岁左右开始出现双乳增大,无阴茎及睾丸的发育,无胡须,无喉结发育,眉毛、腋毛、阴毛稀疏,15、16岁时身高增长快,20岁左右停止生长,身高与正常人无异.     

沂水县中小学生青春发育期调查

沂水县中小学生月经初潮平均年龄城镇与乡村分别为13. 19岁和14. 08岁(中位数),首次遗精平均年龄分别为15. 04和15. 56岁(中位数)。初潮以夏、春季为多,首次遗精均以春季为多。同年龄组已来月经女生及首次遗精男生的身高、体重显著高于未来月经和未发生遗精学生(P<0. 01) 。第二性征出现顺序:女生依次是乳房、阴毛、腋毛;男生是喉结、阴毛、音变、腋毛。     

Age of treatment of undescended testis--a study

A retrospective study was conducted for a period of 4 years during 1992-1995 at Medical College Hospital, Alappuzha, Kerala to find out whether boys with undescended testis got treated at ideal age. Discharge summaries of boys who were treated for undescended testis in this hospital were studied. There were 139 patients with 162 undescended testes. Mean age of operation was 5 years (range--11 months to 12 years). There were 19.4% patients who were less than 2 years of age. It was found out that 11.1% of total testes were atrophic/vanished. Orchiopexy was done in almost all remaining cases. Majority of boys with undescended testis attended for treatment at a higher age than that recommended. The ideal age of treatment at present and its scientific basis are highlighted.     

Prepubertal testicular tumours in Kashmir--a histopathological report of 15 cases

A total of 15 cases of prepubertal testicular tumours were reported by the department of pathology, Government Medical College, Srinagar, Kashmir over a period of 15 years, from January 1984 to December 1998. The cases included yolk sac tumour (10 cases; 67%), teratoma [(mature) 2 cases (13%)], rhabdomyosarcoma [(paratesticular) 2 cases (13%)] and NHL-Burkitt's lymphoma [one case (7%)]. The youngest patient was 10 months old and the oldest was of 14 years age. Ten cases (67%) occurred at or below the age of 4 years. The youngest patient had yolk sac tumour and oldest had rhabdomyosarcoma. In 2 cases both the testes were involved with one of these two cases having bilateral undescended testes.     

Kallmann syndrome: a case of hypogonadotropic hypogonadism

An eighteen years old boy hailing from Nandail, Mymensingh was complaining of small external genitalia, small testes, and gradual enlargement of breast, weight gain, absence of facial, axillary and public hair, absence of sense of smell. His height was 162 cm, weight 59 kg, BMI-22.52 kg/m2 with eunuchoid body habitus. His stretch penile length was 5 cm, testicular volume < 5 ml, stage B3 development of breast and absence of facial, axillary and public hair. He was found anosmic of standard odors. Patient was clinically and biochemically in euthyroid state with low level of testosterone, LH and FSH and normal serum prolactin level. He was diagnosed as a case of hypogonadotropic hypogonadism due to Kallmann syndrome.     

Teenagers'' Sexual Behavior in Sweden, Europe

Objective To investigate the development of sexuality from early to late adolescence,and to compare girls and boys of different agesMethods A cross sectional survey in all schools was performed covering all pupilsbetween 13 and 18years of age that were in school when the survey was conducted. Avalidated instrument, Q90, created for use in teenagers was distributed in the class-rooms to 3 216 teenagers. Q90 covers 30 questions about body development andsexual behavior. Non-response was insignificant (n=19; 0. 6%).Results Pubertal development was considered "early" or "late" by about 50% ofboth boys and girls. Eighty percent of the 13 to 15 years old boys and girls had had aromance and 30% had experience of sexual cuddling (petting), while significantlymore girls than boys had sexual intercourse (18% vs 13%; odds ratio 1.5, 95% CI1.1-1.9). The difference between girls and boys remained in those being 16-18 yearsold, where 63% of the girls and 53% of the boys (odds ratio 1.5, 95% CI 1.2-1.9)admitted having intercourse. Mean age at first intercourse was 14.9 and 15 years,respectively. At 16-18years of age, 23% of the sexually active girls, as compared with25% of the boys estimated that they had had 6 or more sexual partners. About 30% ofthe adolescents, irrespective of age and gender, did not use contraceptives at theirfirst and latest intercourse. Eight percent of the older girls had been pregnant, andthey had an increased history of sexually transmitted infections, as compared withthe boys (6.2% vs 2.7%; odds ratio 2.4, 95% CI 1.2-5.0).Conclusion Exploring sexuality and experimentation is a normal behavior inadolescence. The results of this study, however, indicate that there are substantialgroups of teenagers who practice sexual risk-taking. In addition to general sexualeducation, programs should also be directed to define sexual risks and its consequences.     

Deficiency of 17 alpha-hydroxylase associated with absent gonads.

A phenotypic female presented initially at the age of 17 years with amenorrhoea and delay of sexual development. Karyotype was male, 46 XY, and as gonads were absent, a diagnosis of congenital anorchia was made. The patient was treated with oestrogen. At the age of 23 years, she re-presented with tall stature and hypertension. She then had normal female habitus but absent pubic and axillary hair. Re-investigation showed that sex steroids and cortisol were absent and established the diagnosis as 17 alpha-hydroxylase deficiency. Treatment with hydrocortisone rapidly corrected the hypertension. Ultrasound examination confirmed the absence of gonads but showed that a small uterus was present. Measurement of serum cortisol is important for recognition of such patients, but further measurements of sex steroids, particularly progesterone, are needed to prove the diagnosis. We have found no previous reports of absent gonads in 17 alpha-hydroxylase deficiency. The association remains unexplained.     

单纯肥胖对男性青少年性发育的影响

目的 :探讨单纯肥胖对男性青少年性发育的影响。方法 :测量 5 8例单纯肥胖青少年 (肥胖组 )和 4 6例同年龄、同身高体重正常者 (对照组 )的体重指数 (BMI)、臀围比值 (WHR)、阴毛发育程度、首次遗精发生率、阴茎大小、睾丸体积 ,放免法测定血清黄体生成素 (LH)、卵泡刺激素 (FSH)、总睾酮 (TT)、雌二醇 (E2 )、催乳素 (PRL)和空腹胰岛素 (INS)水平。结果 :肥胖组的阴毛发育程度、首次遗精发生率、阴茎和睾丸大小均明显小于对照组 ;而血清LH、FSH、PRL、INS均明显高于对照组 ,TT水平明显低于对照组 ,E2 水平 2组差异无统计学意义。肥胖组BMI与阴毛发育程度、阴茎长度、睾丸大小、血清TT水平呈显著负相关 ,r分别为 - 0 .2 91 ,- 0 .30 2 ,- 0 .31 7,- 0 .31 9,P均 <0 .0 5。BMI及WHR均与空腹INS水平呈正相关 ,r分别为 0 .30 1 ,0 .35 7,P均 <0 .0 5。结论 :肥胖引起男性青少年性发育滞后。     

Tanner发育阶段女生自评现状及其与相对青春发动时相的相关性分析

目的:调查小学四年级至初中三年级女性学生Tanner发育阶段自评现状,并探讨Tanner发育阶段和相对青春发动时相的相关性。方法:采用分层随机整群抽样法抽取蚌埠市5所学校小学四年级至初中三年级共1 113名女性学生,采用Tanner发育阶段自评图和相对青春发动时相问卷进行调查。结果:Tanner发育阶段指标中,乳房发育TannerⅡ、Ⅲ、Ⅳ期P₅₀年龄分别是9.71、12.06、15.03岁,阴毛发育TannerⅡ、Ⅲ、Ⅳ期P₅₀年龄分别是10.99、12.39、14.98岁。月经初潮P₅₀年龄是11.71岁。Tanner发育阶段（乳房、阴毛、月经）与相对青春发动时相各指标间均呈显著正相关关系（P<0.01）。结论:自我评定Tanner发育阶段青春发动的顺序为首先出现乳房发育,然后开始阴毛发育,最后出现月经初潮,自我评定的Tanner发育阶段与相对发动时相具有一致性。     

高位隐睾应用“长袢输精管”睾丸固定术12例报告

对于高位隐睾不能Ⅰ期手术降入阴囊者采用了“长袢输精管”固定术,共治疗12例17侧隐睾,16侧效果满意。随访中对睾丸部位、大小、弹性作了估价。认为手术成功的关键在于高位切断精索、保留输精管血管及睾丸引带侧支。