精神分裂症认知功能简明成套测评量表（中文版,BACS）信度、效度研究

目的对精神分裂症认知功能简明成套测评量表（中文版,BACS）的信度、效度进行测试。方法选取56例符合CCMD-3诊断标准的新近住院精神分裂症和分裂样精神障碍患者进行精神分裂症认知功能简明成套测评量表（中文版,BACS）评测,并对所获资料进行因子分析和信度分析法。结果①因子分析法显示KMO统计量为0.820,Bartlett球形检验,χ^2=102.430,P〈0.01,主成分分析可将其分为3因子。②各个分测验评分之间的相关系数在0.126～0.582之间,除了伦敦塔和语义流畅性之外,其他均具有显著相关性。③标准化Cronbach α=0.81。④A、B版本亚表之间的相关性在0.736～0.968之间,均具有显著性。结论精神分裂症认知功能简明成套测评量表（中文版,BACS）具有较好的信度、效度,是一种较好的精神分裂症认知功能评测工具,适合汉语地区临床应用。     

中文版偏头痛患者药物依赖性问卷信度和效度研究

目的评价中文版偏头痛患者药物依赖性问卷的信度和效度。方法选取115例合并药物依赖综合征的偏头痛患者,收集其临床资料并进行中文版偏头痛患者药物依赖性问卷的测试。采用重测信度、内部一致性信度评价分析问卷信度,采用内容效度和结构效度评价分析问卷效度。结果量表的重测信度除条目11和条目16为0.558和0.443以外,其余条目的重测信度均大于0.7。总量表的Cronbach’α系数为0.820,各个维度的Cronbach’α系数均0.7。量表的各条目得分和相应维度总分之间的相关系数在0.595~0.962之间。因子分析共提取7个特征根大于1的因子,可解释总变异的76.3%,在相应项目上均有较强的因子载荷。结论中文版偏头痛患者药物依赖性问卷具有较好的信度和效度,适合临床推广应用。     

健康状况调查问卷应用于精神分裂症患者中的信度和效度

目的 评价健康状况调查问卷(SF-36)在住院精神分裂症病人中的信度和效度。方法 通过面对面访谈方式调查90例住院精神分裂症患者,信度采用重测法、内部条目一致性分析(Cronbach’sα系数)。效度采用平行效度,用生活满意度指数A(LSIA)和简明精神病量表(BPRS)作为效标,与SF-36作相关分析。结果 整个测量的重测相关系数均大于0.469(P<0.01),内部一致性(Cronbach’s α系数)在0.73～0.96。平行效度:SF-36中的躯体功能、总体健康、生命活力、精神健康4个分量表与LSIA有较好相关性;总体健康、生命活力、社交功能、情感问题所致的角色受限、精神健康5个分量表与BPRS呈显著性负相关。 结论 SF-36是全面评价精神分裂症病人生命质量有效和可靠的量表之一。     

Yale-Brown强迫量表中文版的信度和效度

目的评价中文版Yale-B rown强迫量表Y-BOCS的信度和效度。方法对110名强迫症患者进行Y-BOCS、HAMD、HAMA的评定。结果Y-BOCS评定者间一致性好,各条目及量表总分的ICC≥0.82;重测信度良好,各条目及量表总分的ICC≥0.75;全量表内部一致性系数(Cronbach's alpha)为0.75。Y-BOCS具有较好的内容效度和结构效度,强迫思维分量表(OS)分与HAMA和HAMD量表分存在相关,OS区分效度欠理想结论Y-BOCS中文版具有可接受的信度和效度,具有临床和科研使用的价值。     

Reliability and validity of the Korean version of the Trunk Control Measurement Scale (TCMS-K) for children with cerebral palsy

The Trunk Control Measurement Scale (TCMS) was developed by Lieve Heyrman in 2011 to evaluate the clinical features of impaired trunk control ability in patients with cerebral palsy (CP). This study aimed to demonstrate the reliability and validity of the Korean version of the Trunk Control Measurement Scale (TCMS-K) for children with CP. Fifty children with spastic CP (mean age 9.08 ± 3.75) participated in the study. They were classified using the Gross Motor Function Classification System and the Manual Ability Classification System. The intraclass correlation coefficient (ICC) value of the inter-rater reliability for the TCMS-K was .987–.998, and the intra-rater reliability was .947–.996. The Spearman rank correlation coefficient between the TCMS-K and the Gross Motor Function Measure-B dimension was .860. The results of the study support that the TCMS-K has a high reliability and validity, which is similar to the original version. Thus, the TCMS-K is a suitable evaluation tool to assess the qualitative performance of trunk control and sitting balance for children with CP, and we expect that it will be a very useful tool for clinicians and researchers.     

Reliability and validity of the Danish version of the Calgary Depression Scale for Schizophrenia

Depressive symptoms within the range of schizophrenic syndromes constitute a major diagnostic and therapeutic problem. Earlier research has indicated that available depression scales are not adequate when examining mood disturbances in patients with schizophrenia. We have made an attempt to estimate the reliability and validity of the Danish version of the Calgary Depression Scale for Schizophrenia. The external validity has been analysed in relation to the Major Depression Inventory (MDI). The internal validity has been analysed by using Loevinger's coefficient of homogeneity as the primary statistic. For the inter-observer reliability the intra-class coefficients have been calculated. It was shown that a subscale of the Calgary scale has sufficient reliability and validity.     

Eppendorf精神分裂症量表中文版的信度和效度

目的：研究Eppendorf精神分裂症量表(ESI)中文版的信度和效度。方法：信度评价采用分半信度、内部一致性、重测信度。效度评价采用区分效度、内容效度、平行效度、结构效度。结果：KSI量表和各因子的分半信度为0．8087—0．9738，Cronbach α系数为0．7694—0．9508；1周后重测信度为0．677—0．876。各因子与总分的相关系数在0．815—0．909之间，因子之间的相关小于因子与总分的相关；ESI与阳性症状与阴性症状量表(PANSS)有很好的相关性，因子分析得出4个因子与原作者的因子相关系数在0．747—0．943之间。结论：ESI量表有较好的信度和效度，值得推广和使用。     

A combination of the korean version of the mini-mental state examination and korean dementia screening questionnaire is a good screening tool for dementia in the elderly

Objective

The aim of this study is to investigate whether a combination of the Korean version of the mini-mental state examination (K-MMSE) and the Korean dementia screening questionnaire (KDSQ) is better than the use of test alone when differentiating patients with dementia from those without dementia in Korea.

Methods

The subjects (patients without dementia, 1120; patients with dementia, 908) were recruited from the Clinical Research Center for Dementia of South Korea. K-MMSE and KDSQ were used. Diagnosis of dementia was made according to the Diagnostic and Statistical Manual of Mental Disorders, fourth Edition. The weighted sum rule derived from logistic regression analysis was used for the combination of K-MMSE and KDSQ.

Results

On comparing the Area Under the Curve for each test using the method of Hanley and McNeil, the weighted sum was significantly greater than KDSQ or K-MMSE, and K-MMSE was significantly greater than KDSQ.

Conclusion

This study shows that when differentiating patients with dementia from those without dementia in Korea, a combination of K-MMSE and KDSQ achieved using the weighted sum method is better than either test performed alone. Further epidemiological studies in community-based settings are required before our results can be generalized to nonclinical samples.     

加里福尼亚痴呆行为问卷的信度和效度检验

目的：检测加里福尼亚痴呆行为问卷（ＣＤＢＱ）的信度与效度。方法对６０例Ａｌｚｈｅｉｍｅｒ病（ＡＤ）患者进行测试,其中有４８例患者完成二倍照料者的联合评定。结果ＣＤＢＱ具有良好的内部一致性,Ｃｏｒｎｂａｃｈ’ｓα＝０．７８６３,ｐ〈０．０１,联合检测的一致性高,ＩＣＣ＝０．８５０８,Ｐ〈０．０１。与简明精神病量表（ＢＰＲＳ）评分相比,相关系数ｒ＝０．３６,Ｐ〈０．０１,平行效度较好。结论ＣＤＢＱ中译     

精神分裂症认知功能成套测验中文版临床信度及效度的研究

目的 对中文版精神分裂症认知功能成套测验(MCCB)的信度及效度进行临床测试.方法 对122例符合美国精神障碍诊断与统计手册第4版精神分裂症诊断标准的住院患者(患者组)进行MCCB测验,4周后重测,同期接受威斯康星卡片分类测验(WCST)、瑞文推理测验(RAVEN)、色词测验(Stroop)及阳性和阴性症状量表(PANSS)测查;并与122名性别、年龄和文化程度与患者组相匹配的社区正常人(对照组)进行比较.结果 (1)MCCB重测相关系数为0.88,P<0.001;(2)评定者间组内相关系数为0.97,P<0.001;(3)MCCB的A、B版本间的复本相关系数为0.64～0.74,P<0.001;A、B版本间的差异无统计学意义(P>0.05);(4)患者组各个分测验得分均低于对照组(P<0.001);逻辑回归分析,用MCCB区分精神分裂症患者与正常人,符合率达到84.8%(P<0.001),敏感性83.6%,特异性86.1%;(5)关联效度:MCCB与WCST、RAVEN和Stroop呈显著性相关(r=0.54～0.55),P<0.001;(6)结构效度:验证性因素分析证明中文版MCCB与英文版7个维度结构模型拟合良好;(7)MCCB平均完成时间为(58±10)min,耐受性和操作性达到中等偏上水平.结论 中文版MCCB的重测信度、评定者间信度、同质性信度、复本信度、关联效度、结构效度和效标效度等指标满足心理测量学要求,MCCB作为精神分裂症患者认知功能疗效评估的新标准,值得进一步修订和完善.     

Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome.

BACKGROUND: The prodromal phase of schizophrenic disorders has been described prospectively. The present study aimed to determine the short-term efficacy and safety of olanzapine treatment of prodromal symptoms compared with placebo. METHODS: This was a double-blind, randomized, parallel-groups, placebo-controlled trial with fixed-flexible dosing conducted at four sites. Sixty patients met prodromal diagnostic criteria, including attenuated psychotic symptoms, as determined by structured interviews. Olanzapine 5-15 mg daily or placebo was prescribed for 8 weeks. RESULTS: In the mixed-effects, repeated-measures analysis, the treatment x time interaction for the change from baseline on the Scale of Prodromal Symptoms total score was statistically significant, and post hoc analyses revealed that the olanzapine-placebo difference reached p<.10 by week 6 and p<.05 at week 8. Ratings of extrapyramidal symptoms remained low in each group and were not significantly different. Olanzapine patients gained 9.9 lb versus.7 lb for placebo patients (p<.001). CONCLUSIONS: This short-term analysis suggests olanzapine is associated with significantly greater symptomatic improvement but significantly greater weight gain than is placebo in prodromal patients. Extrapyramidal symptoms with olanzapine were minimal and similar to those with placebo. Future research over the longer term with more patients will be needed before recommendations can be made regarding routine treatment.     

汉密顿抑郁量表6项版本(HAMD-6)的信度及效度研究

目的检验汉密顿抑郁量表6项版本(HAMD-6)的信度与效度。方法选用汉密顿抑郁量表6项版本(HAMD-6)与24项版本(HAMD-24)对264例住院及门诊抑郁症患者和32名正常对照进行了评定;并对随机抽取的34例住院患者在第1次评定后3天进行第2次评定;由经培训的2名评定员对其中的10名抑郁症患者同时施行量表评定,进行评分者信度研究;将HAMD-6与另3个版本(17项、21项、24项)进行相关分析,进行效度研究。结果HAMD-6的内部一致性系数Cronbachs的α为0.474,条目间的平均相关系数为0.131,34例患者重测HAMD-6的相关系数为0.951(P<0.01),评定员HAMD-6相关系数为0.989(P<0.01);HAMD-6各条目与总分的相关系数r在0.294~0.645之间(P<0.01);患者组同正常对照组HAMD-6总分经t检验,差异具有显著性(P<0.01);264例抑郁症患者HAMD-6总分与另3个版本总分显著相关,r为0.638~0.683(P<0.01)。结论HAMD-6同广泛使用的其他版本一样具有较高的信度与效度,并由于条目简洁,操作方便,易于掌握和节省时间,值得在临床推广使用。     

冗思反应量表中文版在抑郁障碍患者中的运用结果分析

目的 评价冗思反应量表中文版(RRS-C)在抑郁障碍患者中的信、效度.方法 212例抑郁障碍患者完成了RRS-C和流调中心抑郁量表(CES- D),分析RRS-C的Cronbach'sα系数、条目间平均相关系数、总分和各因子的相关系数,并采用验证性因子分析考察其三因子结构.结果 RRS-C总量表的Cronbach's α系数为0.88,三因子的Cronbach's α系数在0.67～0.84;总量表的条目间平均相关系数为0.26,量表总分和各因子间的相关系数在0.71～0.94,各因子条目间平均相关系数在0.29～0.32;验证性因子分析指标(CFI=0.913;GFI=0.905;x2/v＜2;RSMEA=0.072)均符合测量学要求.结论 RRS-C在抑郁障碍患者中有良好的信、效度,可应用于我国抑郁障碍患者冗思特征的测评.     

Cornell痴呆抑郁量表的信度和效度检验

目的检测Cornell痴呆抑郁量表的信度和效度.方法对60例痴呆患者进行测试,由四位医生进行联合评定.结果Cornell痴呆抑郁量表具有良好的内部一致性,联合评定ICC=0.87、F=24.59,P＜0.01.与HAMD量表评分相比,相关系数r=0.833,P＜0.01.平行效度好,在判断抑郁程度方面F值为0.01,P＜0.01.结论Cornell痴呆抑郁量表具有良好的我信度和效度,值得在临床推广.     

自知力量表的信度和效度初步研究

目的：对Markova和Berrios研制的自知力量表作信度、效度检验,进行可靠性研究,方法：初测62例精神分裂症患者获得信度、效度检验结果。对原量表进行修订,修订后量表用于120例精神分裂症患者的测评,核对信度、效度检验结果。结果;原量表经62例精神分裂症患者测评,Cronhach的α系数为0．814、分半信度为0．828、重测信工为0．764。修订后量表经120例精神分裂症患者测评,Cronbach的α系数为0．967、分半信度为0．826、重测信度为0．776。原量表及修订后量表在量表总体和量表的条目组均显著良好效度。结论：该量表具有良好的信度及效度,为进一步实验研究和临床评估中使用提供了量表的测量依据。     

Reliability and validity of Japanese version of the Mini-International Neuropsychiatric Interview

The Mini-International Neuropsychiatric Interview (MINI) is a short, structured diagnostic interview used as a tool to diagnose 16 axis I (Diagnostic and Statistical Manual) DSM-IV disorders and one personality disorder. Its original version was developed by Sheehan and Lecrubier. We translated the MINI into Japanese, and investigated the reliability and validity of the Japanese version of MINI. Eighty-two subjects participated in the validation of the MINI versus the Structured Clinical Interview for DSM-III-R (SCID-P). One hundred and sixty-nine subjects participated in the validation of the MINI versus an expert's professional opinion. Seventy-seven subjects were interviewed by two investigators and subsequently readministered by a third interviewer blind to the results of initial evaluation 1-2 days later. In general, kappa values indicated good or excellent agreement between MINI and SCID-P diagnoses. Kappa values indicated poor agreement between MINI and expert's diagnoses for most diagnoses. Interrater and test-retest reliabilities were good or excellent. The mean durations of the interview were 18.8 min for MINI and 45.4 min for corresponding sections of SCID-P. Overall, the results suggest that the MINI Japanese version succeeds in reliably and validly eliciting symptom criteria used in making DSM-III-R diagnoses, and can be performed in less than half the time required for the SCID-P.     

A Study of the Reliability and Validity of the Korean Version of the Penn Alcohol Craving Scale for Alcohol-Dependent Patients

Objective

The Penn Alcohol Craving Scale (PACS) is a stronger predictor of subsequent drinking and relapse of alcohol dependence that can be administered more quickly and easily than other craving scales. The goal of this study was to develop the Korean version of the Penn Alcohol Craving Scale (PACS-K).

Methods

To examine the psychometric properties of the PACS-K, responses were chosen from 80 patients admitted to a treatment facility for alcohol dependence.

Results

The PACS-K possesses good psychometric properties, as assessed by Cronbach''s α estimates (Cronbach''s α=0.91). The test-retest reliability of the PACS-K showed high correlation (p<0.01) when the retest interval was 1 day. When the validity of the PACS-K was investigated using correlation analysis with two other craving scales (the Obsessive Compulsive Drinking Scale (OCDS) and the Visual Analogue Scale (VAS), high correlations were obtained between total PACS scores and total OCDS scores, and between total PACS scores and VAS scores (p<0.01, respectively).

Conclusion

The PACS-K is a reliable and valid measure of alcohol cravings, and it could be useful for predicting which individuals are at risk for subsequent relapse.     

Prodromal assessment with the structured interview for prodromal syndromes and the scale of prodromal symptoms: predictive validity, interrater reliability, and training to reliability

As the number of studies related to the early identification of and intervention in the schizophrenia prodrome continues to grow, it becomes increasingly critical to develop methods to diagnose this new clinical entity with validity. Furthermore, given the low incidence of patients and the need for multisite collaboration, diagnostic and symptom severity reliability is also crucial. This article provides further data on these psychometric parameters for the prodromal assessment instruments developed by the Prevention through Risk Identification, Management, and Education (PRIME) prodromal research team at Yale University: the Structured Interview for Prodromal Syndromes and the Scale of Prodromal Symptoms. It also presents data suggesting that excellent interrater reliability can be established for diagnosis in a day-and-a-half-long training workshop.     

个人和社会功能量表在抑郁症中的适用性研究

目的 检测个人和社会功能量表(Personal and Social Performance scale,PSP)在抑郁症患者中的信度和效度,了解PSP在抑郁症中的适用性.方法 在全国6个精神卫生中心收集84例门诊抑郁症患者.所有的病例进行PSP、Montgomery- Asberg抑郁量表(Montgomery- Asberg Depression Rating Scale,MADRS)、大体社会功能量表(Global Assessment of Functioning Scale,GAF)评定,分析PSP在抑郁症患者中的内部一致性、与GAF的一致性以及与MADRS的相关性.另外,6例抑郁症病例在首次评定后的1周进行再次评定用以PSP重测一致性的检验.结果 PSP的内部一致性Cronbach α系数为0.760,PSP总分与GAF评分具有良好的正相关(r=0.906,P＜0.01),与MADRS总分呈负相关,具有统计学意义(r=-0.652,P＜0.01),重测一致性的kappa值为0.945(n=6,P=0.01).结论 PSP是一个操作简单、稳定性高的评估工具,可用于抑郁症患者社会功能的评估.量表中d维度(冲动和攻击行为)对整个量表的权重大,在抑郁症患者中与总分相关性欠佳.     

儿童神经心理缺陷主观意识问卷（SAND-C）在上海儿童中的信、效度初步评估

目的评价儿童神经心理缺陷主观意识问卷（Subjective Awareness of Neuropsychological Deficits questionnaire for Children,SAND-C）在国内儿童中的信、效度。方法对628名9~16岁健康儿童和47例注意缺陷多动障碍（ADHD）儿童进行SAND-C、Piers-Harris儿童自我意识量表（PHCSS）评定,2周后其中的56名健康儿童进行SAND-C重测。结果 SAND-C总分的Cronbachα系数为0.89,各因子分的Cronbachα系数为0.62~0.71。SAND-C的总分和因子分与PHCSS评分呈正相关,健康儿童SAND-C评分均高于ADHD患儿。验证性分析显示本研究数据的因子结构符合原问卷的六因素结构和单因素结构。进一步的探索性因素分析提示,一般认知能力因子、运动与行为控制因子、记忆和语言因子以及注意因子组成的四因子结构优于原问卷结构。结论 SAND-C有较好的信度和一定的疾病鉴别度,但中国儿童使用时,四因子结构更为合适。