阴茎多发性神经鞘瘤1例并文献复习

目的 探讨阴茎多发性神经鞘瘤临床表现及诊治,并行文献复习.方法 报道1例阴茎多发神经鞘瘤.患者以阴茎根部多发结节收治,术前完善彩超、CT及勃起功能检查,拟诊为阴茎硬结症,行结节切除术.结果 结节与阴茎海绵体有明显分界,术后根据病理学特点及免疫组化诊断为阴茎神经鞘瘤,预后良好.结论 阴茎多发神经鞘瘤,临床罕见,主要依靠病...     

阴茎神经鞘瘤的临床特点及诊治(附1例报告并文献复习)

目的 探讨阴茎神经鞘瘤的临床特点及诊治要点.方法 报告1例阴茎神经鞘瘤病例,患者以阴茎根部肿块收治,术前细胞学穿刺报告为神经纤维瘤,行肿瘤切除术.结果 患者术后病理诊断为阴茎神经鞘瘤;术后恢复较好.结论 阴茎神经鞘瘤缺乏特异性临床表现,术前诊断较为困难,穿刺活检有助于诊断及鉴别.确诊需依靠病理学证据,必要时可加做免疫组化,手术切除为主要治疗方法.     

多发性阴茎神经鞘瘤1例

阴茎神经鞘瘤相当罕见 ,我院收治 1例 ,且为多发性 ,现报告如下。患者 ,40岁。 1 993年发现阴茎背侧根部及近冠状沟 2cm处各有一 1mm× 2mm大小肿物 ,1个未予重视。 1 996年近冠状沟处肿物逐渐增大为2mm× 4mm大小 ,在当地医院行手术切除 ,术后病理报告“神经鞘瘤”。近 6年来 ,患者阴茎根部肿物逐渐增大至 5mm× 7mm大小 ,并于阴茎背侧散在出现 4粒类似肿物 ,而入我院求治。体检 :阴茎、阴囊发育正常 ,阴茎背侧根部可触及一直径约 5mm扁圆形质硬肿物 ,表面光滑 ,活动可 ,无压痛 ,阴茎背侧中线附近尚可触及类似肿物 4个 ,散在分布 ,直径 2～…     

原发性膀胱神经鞘瘤1例报告并文献复习

目的 探讨原发于膀胱的神经鞘瘤和恶性周围神经鞘瘤在组织病理学、临床表现、治疗和预后上的特点,确立两者的鉴别诊断思路.方法 回顾1例原发于膀胱的神经鞘瘤的临床诊疗过程,结合有关膀胱神经鞘瘤及膀胱恶性周围神经鞘瘤的文献资料进行分析.结果 在组织病理和免疫组化方面,原发于膀胱的神经鞘瘤和恶性周围神经鞘瘤有明显差异.结论 原发于膀胱的神经鞘瘤临床极其少见,易与膀胱常见肿瘤混淆,造成误诊,免疫组化为重要的确诊依据.膀胱恶性周围神经鞘瘤应以高度恶性的软组织肉瘤进行处理.临床上应重视两种疾病的鉴别,以正确地指导临床诊疗.     

阴囊神经鞘瘤1例报道并文献复习

目的 探讨阴囊神经鞘瘤的疾病特点,提高对阴囊神经鞘瘤的临床诊治水平.方法 对1例阴囊神经鞘瘤病例进行报道,并结合文献报道的7例资料进行分析总结.结果 8例中,良性神经鞘瘤4例,平均直径6.5 cm,平均病程4.4年,年龄34～48岁,平均年龄38.4岁,超声检查提示肿瘤与周围组织界限清楚;1例合并阴茎癌良性神经鞘瘤,患者年龄78岁;3例恶性神经鞘瘤平均直径12.6 cm,平均病程2.2年,平均年龄75岁,超声检查提示肿瘤边界不清,内部回声不均.结论 阴囊神经鞘瘤极为罕见,目前确诊依赖于术后病理检查.对于阴囊肿瘤应尽早手术切除,手术是目前治疗的有效方法,以避免恶性肿瘤的诊治延误.     

腹膜后神经鞘瘤1例报告并文献复习

目的报告1例腹膜后神经鞘瘤,并复习相关文献,分析其临床诊治现状。方法通过对1例腹膜后神经鞘瘤的诊断、治疗方法及术后病理、随访的回顾,结合国内外有关文献报道,综合分析腹膜后神经鞘瘤的诊断及治疗状况。结果本例行手术治疗,术后病理证实为腹膜后神经鞘瘤,随访半年无复发。结论腹膜后神经鞘瘤诊断困难,影像学检查无特异性,确诊依靠病理检查,理想的治疗方法是通过外科手术完整切除肿瘤,其预后良好,早期复发率低。     

阴茎原始神经外胚叶瘤1例并文献复习

目的:探讨原发于泌尿生殖系统的原始神经外胚叶瘤的临床表现、病理特点、治疗方法及预后。方法:分析本院2007年3月收治的1例原发于阴茎的原始神经外胚叶瘤患者的病例资料并复习相关文献。结果:该患者经过病理确诊为阴茎原始神经外胚叶瘤,已采取手术根治,拟进一步化疗。结论:病理及免疫组化有助于对原始神经外胚叶瘤的确诊。对于早期患者手术是首选的治疗方法,晚期患者可以辅助性地行联合化疗,目前原发于阴茎的原始神经外胚叶瘤非常罕见,对预后尚没有评估依据。     

肾上腺神经鞘瘤(附三例报告)

目的 根据３例肾上腺神经鞘瘤。方法 回顾性分析３例肾上腺神经鞘瘤病人的临床资料。结合文献讨论此病的发病情况,病理学特征以及诊治方法。结果 ３例肿瘤均经手术切除,病理学证实良性２例,恶性１例,随访３～５年未见复发,结论 肾上腺神经鞘瘤的术前诊断困难。确诊需经病学检查。手术切除是最佳治疗方法,恶性神经鞘瘤可辅以放疗。     

阴茎多发性血管球瘤1例报告并文献复习

目的:探讨阴茎多发性血管球瘤(GT)的临床病理特征、诊断及鉴别诊断。方法:对1例罕见的阴茎多发性GT的13岁患儿进行临床、组织形态学及免疫组织化学染色观察,并结合文献进行探讨。结果:阴茎多发性GT临床表现为多发的血管团状小结节,有触痛,无红肿,无表面分泌物。镜下肿瘤由丰富的血管和围绕血管生长的多层上皮样瘤细胞组成。血管多为扩张的静脉,似海绵状血管瘤。瘤细胞大小一致,呈圆形或立方形,胞浆淡红色或稍透明,核稍大,圆形或卵圆形,位于细胞中央,核染色质细致均匀,未见明显异型性和核分裂。间质局灶水肿及粘液变性。免疫表型:肿瘤细胞表达SMA、Vimentin。结论:发生于阴茎的多发性GT极其罕见,多发生于儿童,结合患儿临床症状、组织病理学特点和免疫组化标记一般可明确诊断,多发性GT易累及全身和复发,需进行全面查体和术后随访。     

Abducens nerve schwannoma: case report and review of the literature

Schwannomas of the abducens nerve are extremely rare. The authors report a case with this tumor and discuss its clinical and radiographic characteristics. A 36-year-old man presented with 6-month history of diplopia. Right abducens nerve paresis was noted on neurologic examination. Magnetic resonance imaging revealed a 4-cm sized heterogeneously enhancing mass in the right cerebellopontine angle. Although schwannoma was suggested, no direct radiographic evidences regarding its origin were identified. Instead, the facial and vestibulocochlear nerve complex was found to be displaced posteriorly by the tumor on MR three-dimensional T2-weighted driven equilibrium sequence. Resection of the tumor was carried out via retrosigmoid approach. As the encapsulated partially suckable yellowish tumor was debulked and dissected, the abducens nerve was found to fan along and be attached to the medial surface of the tumor, which was cut at this point. Complete excision of the tumor was accomplished, and reanimation of the nerve was done by end-to-end anastomosis. Histologic feature was typical of schwannoma. Abducens schwannoma, although rare, should be taken into account for differential diagnosis of the cerebellopontine angle tumors. Appreciation of the characteristic clinical and radiographic features may provide an accurate preoperative diagnosis.     

后肾腺瘤的临床特征(附1例报告及文献复习)

目的 探讨后肾腺瘤的临床表现及影像学、病理学特征,提高对后肾腺瘤的认识和术前诊断水平.方法 回顾性分析1例后肾腺瘤患者的相关资料并进行相关文献复习.结果 患者术后病理诊断为后肾腺瘤;术后恢复较好,顺利出院.结论 后肾腺瘤的临床特征有限,多为体检时发现,术前需结合生化及影像学检查综合判断,必要时行穿刺病理及术中冷冻病理明确诊断,为患者选择合适手术方式;一般预后良好,但术后仍需定期复查.     

Spinal schwannoma causes acute subarachnoid haemorrhage: A case report and literature review

BackgroundSpinal schwannomas that arise from spinal nerve root sheaths are the most common intradural extramedullary spinal tumours and are often accompanied by nerve roots or spinal cord irritation symptoms. The phenomenon of spinal schwannoma causing subarachnoid haemorrhage (SAH) is rare, with ependymoma of the conus medullaris accounting for most cases.Case reportA 45-year-old man was admitted to our hospital due to progressive lower limb weakness and sudden back pain after hard physical work. The patient had not been able to walk for 2 hours upon admission. An emergency magnetic resonance imaging (MRI) scan showed that the spinal cord at the C6-T4 level was severely compressed by a subdural mass. During the emergency operation, exploration of the dura and arachnoid mater revealed a fresh blood clot covering a tumour located on the ventral side of the spinal cord. The size of the tumour was approximately 3 × 2 × 1 cm without adhesion to the surrounding tissue, but the drainage vein was ruptured. Postoperative pathology showed that the tumour was a schwannoma with areas of fresh haemorrhage and focal necrosis.ConclusionsSpinal schwannomas presenting with SAH are rare events. In our opinion, spinal pathology with rapid progression of neurological symptoms requires early diagnosis and emergency management. Complete excision of haemorrhagic tumours is the goal of treatment to prevent recurrence, which can effectively avoid irreversible damage to the spinal cord resulting from spinal cord compression.     

Pancreatic schwannoma: Report of a case

Among pancreatic neoplasms, pancreatic schwannoma is quite rare. We report a case of solitary pancreatic schwannoma, plus a literature review of this tumor. A 71-year-old woman was diagnosed by abdominal ultrasonography as having a pancreatic tumor and was hospitalized in our department at Kumamoto University Hospital on January 26, 2006. Abdominal computed tomography, magnetic resonance imaging, and endoscopic ultrasonography all showed this tumor, which was located in the body of the pancreas, to have cystic and solid components, and with a septum in the cystic part of the lesion. The tumor, preoperatively identified as a mucinous cystic neoplasm, was clearly separated from the normal pancreatic parenchyma. We performed a spleen-preserving distal pancreatectomy with a lymph node dissection on February 7, 2006. A histopathological examination of the resected specimen by means of hematoxylin and eosin revealed the tumor to consist of two parts: one with a compact spindle cell pattern (Antoni type A), and the other showing degeneration of fat (Antoni type B). We also found positive results for immunohistochemical staining for S-100 and vimentin. These findings confirmed the tumor’s classification as a pancreatic schwannoma.     

Penile schwannoma mistaken for hemangioma: a rare case report and literature review

Penile neoplasm is uncommon. Schwannomas of the penis are especially rare. For this reason, it is difficult to get an accurate impression to enable decision making. This report primarily deals with the mistaken diagnosis of hemangioma, to the surgery, and the follow-up in real-world. A 38-year-old male patient presented with a palpable mass in the penile root that increased in size with erection. One year after the mass had been found, the patient visited the hospital and complained that the mass was growing. Moreover, the patient explained that the mass seemed to increase during penile erection. On physical examinations, a 2 cm mass without tenderness was palpated in the left penoscrotal junction. About 2.1 cm in size, an isoechoic mass was observed next to the corpus cavernosum on ultrasonography. There was high vascularity inside of the mass. Excision and biopsy were decided upon. Following surgery, a schwannoma was confirmed by pathology. After three months, the patient did not complain of any symptoms and had normal erectile function. Most of these tumors are benign. By December 2020, 40 cases were reported, of which 6 were diagnosed as malignant. The most frequent occurrence site is the penile shaft. In all cases, surgical resection was performed and no recurrence was found. The aim of this case report is to assist clinicians in choosing the best treatment option when faced with this rare condition by discussing the radiological, pathological, and clinical course.     

Pancreatic schwannoma: Report of a case and review of literature

Connective tissue tumors of pancreas are uncommon, among them pancreatic schwannoma is very rare tumor, very few cases were reported in literature. Aggressive resections like whipple’s procedure, or distal pancreatectomy are not necessary for pancreatic schwannoma as it rarely goes to malignant change and simple enuclation is sufficient.In our patient pancreatic schwannoma is associated with simple cyst in liver and absence of one kidney. Here, we are presenting a case of pancreatic schwannoma treated by simple enucleation.     

Giant retroperitoneal schwannoma from the fifth lumbar nerve root with vertebral body osteolysis: a case report and literature review

Study design  To report a rare case of retroperitoneal schwannoma from lumbar nerve root with difficult surgery and potential vascular complication. Objective  We report a rare case of giant schwannoma which arises from fifth lumbar root with L5 vertebral body destruction. Summary of background data  Retroperitoneal schwannomas are rare, and those with bony involvement are even rarer and may be mimicking malignant tumors. Methods  Retroperitoneal removal of the tumor with partial killing of right L5 nerve root and allograft of L5 vertebral body defect were performed. Incidental injury of common iliac vein was encountered due to adhesion of the vein to tumor capsule. The laceration was repaired by cardiovascular surgeon. Results  At final follow-up, the patient had mild weakness of dorsi-flexion of right ankle and mild right L5 dermatome numbness. No walking difficulty and no sign of local recurrence in the image studies. Conclusions  Retroperitoneal schwannomas are rare, and they can become very large when diagnosed. Major vessels impingement and adhesion can occur which make the surgery difficult. Careful pre-operative evaluation and explanation is very important.     

Intramedullary melanotic schwannoma. Report of a case and review of the literature

A case of an intramedullary melanotic schwannoma located in the spinal cord at the T2-T3 level is described. The lesion occurred in a 44-year-old woman with a 10-year history of weakness and sensory numbness in both legs and feet. At operation the lesion appeared as a well-demarcated grey-brown intramedullary mass. Histologically, it was composed of interlacing bundles of spindle cells showing their cytoplasm filled with melanin. Among spinal cord neoplasms, melanotic schwannomas are rare tumours, which have apparently been reported only in three previous instances. The clinical, diagnostic and pathological features, as well as the possible aetiology of these rare tumours are discussed.     

A childhood case of intrascrotal neurofibroma with a brief review of the literature

Solitary neurofibroma unassociated with neurofibromatosis type I (NFI) arising within the scrotum is an extremely rare benign tumor. There are 8 cases reported in the literature with only 1 that occurred in childhood. In the current report the authors describe an additional adolescent patient, the second case encountered in childhood and the ninth case reported in the literature, together with a review of the related articles.