Clinical Study on Puncturing Weizhong （BL 40） for Post-stroke Dysfunction of the Lower Limbs

Objective： To observe the clinical effects in the treatment of post-stroke dysfunction of lower limb by puncturing Weizhong （BL 40）. Methods： One hundred and twenty patients were randomly divided into two groups, 60 cases in each group. Both groups were treated by puncturing Weizhong （BL 40） plus functional rehabilitation training, once every day. Those in the observation group were treated by Shi Xue-min＇s needling technique, while others in the control group were treated with routine needling technique. The therapeutic effects were assessed by the scores of lower limb functions of Lovett scale of grading muscle strength （LSGMS） and short-form FugI-Meyer assessment （SFFMA）. Results： The instant and post-treatment effective rates in the observation group were 83.3% and 93.3%, versus 6.7% and 53.3% in the control group, indicating that the therapeutic effect was better in the observation group （P〈0.01）. The instant and post-treatment scores of Lovett muscle strength grading scale were better in the observation group than that in the control group （P〈0.05）. SFFMA score of lower limbs function was better in the observation group than that in the control group （P〈0.0s）. Conclusion： Different needling methods at Weizhong （BL 40） can produce different therapeutic effects in treating post-stroke dysfunction of lower limb, and Shi＇s needling technique has obvious instant effect and therapeutic function.     

Tuina is superior to electroacupuncture in treating thoracic facet joint disorder

Objective： To observe the clinical efficacy of tuina in treating thoracic facet joint disorder, and compare it to the efficacy of electroacupuncture （EA）. Methods： Eighty patients were randomized into a tuina group and an EA group, 40 in each. The tuina group was intervened by tuina manipulations, and the EA group was by EA treatment. Visual analogue scale （VAS）, symptoms and physical signs were evaluated before, and after 5 and 7 treatment sessions respectively, and the clinical efficacies were compared between the two groups. Results： After treatment, the recovery and markedly effective rate was 92.5% in the tuina group versus 47.5% in the EA group, and the difference was statistically significant （P〈0.01）. The total effective rate was 100.0% in the tuina group versus 85.0% in the EA group, and the difference was statistically significant （P〈0.05）. After 5 treatment sessions, the recovery and markedly effective rate was 91.9% in the tuina group versus 68.4% in the EA group, and the difference was statistically significant （P〈0.05）. The VAS scores, and total symptoms and physical signs scores were significantly reduced in both groups after treatment （P〈0.01）, and the scores in the tuina group were significantly lower than those in the EA group （P〈0.01）. Conclusion： Compared to EA, tuina is more efficient and effective in treating thoracic facet joint disorder and has obvious analgesic effect.     

Clinical Observation on Deep Acupuncture at Huantiao （GB 30） for Patients with Chronic Prostatitis

Objective: To observe the clinical efficacy of deep acupuncture mainly at Huantiao (GB 30) for patients with chronic prostatitis. Methods: Forty-two cases of patients with chronic prostatitis were treated with deep acupuncture at Huantiao (GB 30) combined with adjunct acupoints on the base of syndrome differentiation. Ten times treatment was a course, and effects were evaluated after two courses. Results: Among all the 42 cases, 29 cases were cured, 9 cases were improved and 4 cases were invalid, and the total effective rate was 90.5%. Conclusion: It has good effect of deep acupuncture at Huantiao (GB 30) as major acupoint combined with adjunct acupoints on the base of syndrome differentiation for patients with chronic prostatitis.     

Examples of Application of Ligou （LR 5）

To study the application and mechanism of Ligou(LR 5)in the treatment of urinary and reproductive system diseases from its location,meridian,application alone and combined application in clinic based on syndrome differentiation,and to guide its application in clinic.     

Influence of Electroacupuncture at Taichong （LR 3） and Ququan （LR 8） on Hepatic Hemodynamics

Objective： To observe the influence Taichong （LR 3） and Ququan （LR 8） on patients with chronic hepatic diseases. of electroacupuncture hepatic hemodynamics （EA） at in the Methods： Sixty cases with chronic hepatic diseases were randomly divided into a Taichong （LR 3） group and a Ququan （LR 8） group, 30 cases in each group, and were respectively treated with electroacupuncture at Taichong （LR 3） and Ququan （LR 8）. The blood flow results of the hepatic artery and portal vein by color ultrasonic test were used as the objective indexes, to compare and observe the hemodynamics changes of the hepatic artery and portal vein in the patients before and after EA. Results： After EA, in Taichong （LR 3） group, the average velocity, the lowest velocity, resistance indexes and the highest velocity of blood flow of the hepatic artery, and the highest velocity, average velocity of blood flow of the portal vein, blood flow volume of the portal vein （PVBF）, total blood flow volume of the liver （TLBF）, and Doppler blood perfusion indexes of the hepatic artery （DPI） were all statistically different from those before intervention （all P~O,O5）, In Ququan （LR 81 group, the highest velocity, average velocity, lowest velocity and resistance indexes of blood flow of the hepatic artery, and the highest velocity and average velocity of blood flow of the portal vein, and PVBF were significantly different from those before intervention （P〈0.05）. The TLBF and DPI were significantly different from those before intervention （P〈0.01）. All various indexes were not statistically different between the two groups. Conclusion： EA at Taichong （LR 3） and Ququan （LR 8） can speed up blood flow velocity of the portal vein, increase PVBF, increase the TLBF, increase the resistance indexes of the hepatic artery, decrease the blood flow velocity of the hepatic artery, and decrease DPI in the liver.     

Moxibustion on Shenque （CV 8） Improves Effect of Acupuncture for Diarrhea-predominant Irritable Bowel Syndrome

Objective： To observe the clinical effect of acupuncture and moxibustion on diarrhea-predominant irritable bowel syndrome （IBS-D）. Methods： A total of 60 IBS-D patients were randomly allocated into a treatment group and a control group, 30 in each group. Patients in the treatment group were treated with acupuncture combined with ginger and salt-partitioned moxibustion on Shenque （CV 8）, whereas patients in the control group only received acupuncture treatment. Six days made up a course of treatment, and the clinical effects were statistically analyzed after 4 courses. Results： The overall response rate in the treatment group was 96.7%, versus 76.7% in the control group, showing a statistical significance （P〈0.05）. In the intra-group comparison of the symptom scores after treatment, there were statistical differences in both groups （both P〈0.01）, and in the inter-group comparison, the difference was statistically significant （P〈0.05）. Conclusion： Acupuncture combined with ginger and salt-partitioned moxibustion on Shenque （CV 8） can obtain better effect for ISB-D than acupuncture alone.     

Clinical Study on Moxibustion at Shenque （CV 8） for Chronic Urticaria

Objective： To observe the safety and efficacy of moxibustion at Shenque （CV 8） for chronic urticaria. Methods： A total of 80 cases who met the inclusion criteria were randomly allocated into a treatment group and a control group, 40 in each. Cases in the treatment group were treated with thunder-fire moxibustion at Shenque （CV 8）, whereas cases in the control group were treated with Mizolastine. Changes in clinical symptoms such as itching and skin lesion were observed before and after treatment and the therapeutic efficacies were assessed. Results： After treatment, the total scores of clinical symptoms in both groups were markedly reduced （P〈0.05）, and the reduction was more significant in the treatment group than that in the control group （P〈0.05）. The total effective rate in the treatment group was 77.5%, versus 65.0% in the control group, showing no significant difference （P〉0.05）. The Ridit analysis showed a between-group significant difference in therapeutic efficacy grades （P〈0.05）. There were no reports of adverse reactions in the treatment group and 2 cases experienced mild somnolence in the control group. Conclusion： With an exact effect for chronic urticaria, moxibustion at Shenque （CV 8） obtained better results in overall efficacy and improving symptoms than oral administration of Mizolastine.     

Warm Needling Moxibustion at Zhongji （CV 3） and Zusanli （ST 36） for Urinary Retention after Gynecological Surgery

Objective： To observe the clinical Zhongji （CV 3） and Zusanli （ST 36） gynecological surgery. effect of warm needling moxibustion at in treatment of urinary retention after Methods： Forty patients with urinary retention after gynecological surgery were randomly divided into two groups by the randomized method, 20 cases in each group. Patients in the treatment group were treated by warm needling moxibustion at Zhongji （CV 3） and Zusanli （ST 36）. Patients in the control group were treated by inductive urination. The therapeutic effects of the two groups were observed after one course of treatment. Results： The total effective rate was 95.0% in the treatment group and 70.0% in the control group. The difference in the total effective rate between the two groups was statistically significant （P〈O.05）. Conclusion： Warm needling moxibustion at Zhongji （CV 3） and Zusanli （ST 36） is more effective than inductive urination in treating urinary retention after gynecological surgery.     

Therapeutic Efficacy Observation on ＇Setting Fire on the Mountain＇ Manipulation by Lu $hou-yan for Cervical Radiculopathy

Objective： To observe the clinical effect of ＇setting fire on the mountain＇ manipulation by Lu Shou-yan for cervical radiculopathy as well as the infrared thermographic changes of the cervical area before and after treatment. Methods： A total of 120 eligible cases with cervical radiculopathy were randomly allocated into an observation group and a control group, 60 in each group. Cases in the observation group were treated with Lu Shou-yan＇s ＇setting fire on the mountain＇ manipulation, whereas cases in the control group were treated with even reinforcing-reducing manipulation. After two courses of treatment, the infrared thermographic changes and overall therapeutic efficacies in the two groups were compared. Results： The recovery rate and total effective rate in the observation group were 68.3% and 98.3% respectively, versus 28.3% and 81.7% in the control group, showing statistical differences in recovery rate and total effective rate （both P〈 0.01）. There was between-group statistical significance in comparing the infrared thermography after treatment （P〈O.01）. Conclusion： ＇Setting fire on the mountain＇ manipulation by Lu Shou-yan is better than even reinforcing-reducing manipulation for cervical radiculopathy.     

Acupoint Sticking at Shenque （CV 8） with Ginger-preparedBan Xia （Rhizoma Pinelliae） for Nausea and Vomiting Induced by Amifostine

Objective： To observe the treatment effect of acupoint sticking at Shenque （CV 8） with ginger-preparedBan Xia （Rhizoma Pinelliae） on nausea and vomiting induced by Amifostine for myelodysplastic syndromes （MDS）. Methods： Totally 124 eligible subjects intervened by Amifostine were randomized into 2 groups by the visiting order,an observation group and a control group,62 in each group. The control group was intervened by conventional treatment, while the observation group was by acupoint sticking at Shenque （CV 8） with ginger-preparedBan Xia （Rhizoma Pinelliae） in addition to the same conventional treatment. The occurrence rate of nausea and vomiting in the two groups were observed. Results： After intervention, the occurrence rate of nausea and vomiting in the observation group was significantly lower than that in the control group （P＆lt;0.01）. Conclusion： Acupoint sticking at Shenque （CV 8） with ginger-prepared Ban Xia （Rhizoma Pinelliae）can produce a content effect on nausea and vomiting induced by Amifostine for MDS.     

浅谈委中穴与承山穴针刺深度的临床应用

李志道教授经过50余年临床实践研究,结合解剖学相关知识,发现委中、承山二穴在针刺深度与传统认识有所不同。其中,委中穴在刺入0. 5~0. 8寸,承山穴在刺入2. 0~3. 0寸时最易达到循经得气的效果,通过调整针尖方向还可较准确达到气至病所的效果,且针感与相应神经分布区域相吻合。该针感在某些疾病,尤其神经压迫相关症状的治疗中疗效明显,且优于传统教材所述针刺深度。     

针刺委中穴正电子发射计算机体层摄影/CT脑功能成像的观察

目的 应用正电子发射计算机体层摄影（PET）／CT脑功能成像技术,观察针刺委中穴在脑内引起的代谢变化,探讨针刺疗法的中枢调节机制。方法 电针刺激8名健康志愿者右侧委中穴,同时行PET／CT脑功能成像,采用相同扫描技术对同8名受试者行无任何穴位刺激的PET／CT脑功能成像。使用统计参数图（SPM）的配对t检验模型,对比针刺委中穴组与静息对照组的差异脑功能图。结果 根据布劳德曼区（Broadmann area,BA）,（1）针刺诱发的平均功能激活脑区：左侧BA10、11、22、38、39、40、44、45、46,右侧BA10,双侧BA19、18以及左侧小脑皮层、屏状核、岛叶（t〉3．36,P〈0．01,k〉30voxels）;（2）针刺诱发平均功能抑制脑区：双侧BA24,左侧BA7、8、19、40,右侧BA1、3、6、20、44和左侧黑质。结论 委中穴与大脑存在着一定的联系,针刺委中穴是通过激活和抑制有功能联系的多个特异脑功能区,并通过神经体液机制共同发挥作用。其中前额区、岛叶及小脑的功能激活和扣带回、顶叶及黑质的功能抑制分析是针刺委中穴的中枢调节机制之一。本研究证明,PET／CT脑功能成像技术有助于揭示中医经络理论,为针刺疗法提供中枢调节机制的可视性试验依据。     

雀啄刺委中穴对脑梗死患者下肢体感诱发电位的影响

目的观察雀啄刺委中穴对脑梗死患者下肢体感诱发电位(SEP)的影响。方法急性脑梗死患者47例随机分为治疗组(雀啄刺委中穴)24例与对照组(直刺委中穴)23例,比较两组患者治疗中及治疗后患肢SEP的变化。结果治疗组患肢的P40波幅增高、潜伏期缩短,与对照组比较差异有统计学意义。结论雀啄刺委中穴能使脑梗死患者下肢SEP的P40潜伏波幅增高、潜伏期缩短,较之普通直刺法更为有效。     

温针灸配合委中穴拍打放血治疗腰椎间盘突出症43例临床观察

目的 观察温针灸配合委中穴拍打放血治疗腰椎间盘突出症的临床疗效.方法 将86例腰椎间盘突出症患者随机分为治疗组和对照组各43例,治疗组给予温针灸配合委中穴拍打放血,对照组给予单纯温针灸治疗.两组均每日1次,治疗7次为1个疗程,疗程间隔2天,治疗3个疗程后统计疗效.治疗后比较两组临床疗效、疼痛评分,并检测治疗前后血清中C反应蛋白(CRP)、白细胞介素-1(IL-1)、白细胞介素-6 (IL-6)、β-内啡肽(β-EP)含量. 结果 治疗组与对照组临床疗效总有效率分别为92.68％、85.71％,治疗组优于对照组(P＜0.05).与治疗前比较,两组疼痛评分均显著降低(P＜0.05);治疗后两组疼痛评分比较,治疗组均低于对照组(P＜0.05).与本组治疗前比较,两组CRP、IL-1、IL-6均明显降低,β-EP均明显升高(P＜0.05).治疗后治疗组IL-1、IL-6低于对照组,β-EP高于对照组(P＜0.05).结论 温针灸配合委中穴拍打放血能更有效改善腰椎间盘突出症患者的疼痛,提高临床疗效.     

电针加委中刺血治疗急性腰椎间盘突出症

目的:探寻治疗急性腰椎间盘突出症的较佳疗法.方法:将100例患者随机分为两组.观察组52例,采用电针疗法,穴取腰阳关、大肠俞、关元俞、小肠俞为主,结合委中附近瘀络刺血治疗;对照组48例,采用牵引配合电针,穴取夹脊穴、肾俞、大肠俞为主,观察两组疗效并进行比较.结果:观察组治愈率为55.8%,愈显率为82.7%,对照组分别33.3%、54.2%,组间差异均有统计学意义(P＜0.05,P＜0.01).结论:电针结合委中附近瘀络刺血治疗急性腰椎间盘突出症疗效显著.     

针刺委中穴对轻中度腰痛局部温度变化的影响

目的:利用红外热成像仪观察针刺委中穴、曲泉穴及非经非穴对轻中度腰痛患者腰部局部的温度变化响。方法:2016年11月至2017年3月从北京中医药大学的在校学生中招募腰痛ODI评分为50%以下的轻中度腰痛受试者75例,随机分观察组(针刺委中穴)25例、对照组1(针刺曲泉穴)25例、对照组2(针刺非经非穴)25例。分别利用红外热成像仪观察针刺前、针刺后2 min、5 min、10 min、15 min、20 min、25 min、30 min、出针后5 min的腰部局部温度变化。结果:3组受试者在针刺过程中腰部温度均有不同程度的变化,针刺委中组相对于针刺曲泉组和非经非穴组温度升高的时间长,升高的总例数高于其他组(P0.05),温度升高节段多聚集在L3~5。结论:针刺委中及腘膝部其他穴位均能使腰部局部温度升高,但委中组温度升高幅度大、持续时间长。     

Effect of electroacupuncture at Huantiao (GB 30) and Weizhong (BL 40) on serum IgG and IgM in rabbits with lumbar intervertebral disc herniation

Objective

To observe the effect of electroacupuncture (EA) at Huantiao (GB 30) and Weizhong (BL 40) on thigmesthesia, gait function, and expression levels of serum immunoglobulin G (IgG) and immunoglobulin M (IgM) in rabbits with lumbar intervertebral disc herniation (LIDH).

Methods

Forty healthy New Zealand rabbits were randomly divided into a blank control group, a model group, an EA at acupoint group and an EA at non-acupoint group, with 10 rabbits in each group. The LIDH pathological model of rabbit was established using the self-made LIDH model maker. The thigmesthesia and gait function of rabbits were recorded by Siegal method. The serum IgG and IgM expression levels were detected by enzyme-linked immunosorbent assay.

Results

EA at Huantiao (GB 30) and Weizhong (BL 40) could improve the clinical symptoms of thigmesthesia and gait function, and inhibit the expressions of serum IgG and IgM in the LIDH rabbits, which were significantly different compared with those in the model group and EA at non-acupoint group.

Conclusion

EA at Huantiao (GB 30) and Weizhong (BL 40) can improve the clinical symptoms of LIDH rabbits, which is associated with inhibition of the serum IgG and IgM expressions and reduction of the immunoinflammatory factor release. This may be one of the mechanisms of EA at Huantiao (GB 30) and Weizhong (BL 40) in the treatment of LIDH.

     

多时间点观察电针“委中”对大鼠腰多裂肌损伤后IGF1R和IGFBP3的表达

目的:研究多时间点电针"委中"穴对大鼠腰多裂肌损伤后1型胰岛素样生长因子受体(IGF1R)和胰岛素样生长因子结合蛋白3(IGFBP3)的表达。方法:选取90只雄性SD大鼠并将其随机分成空白组、模型组、电针委中组,每组30只,模型组和电针委中组腹腔麻醉后往双侧L_(4-5)多裂肌注射0.5%布比卡因溶液制造多裂肌损伤模型,空白组不做处理,造模后电针委中组行1次/d电针委中穴治疗,3组分别于治疗后1 d、2 d、3 d、7 d、14 d后同步取材,通过Western Blotting法观察多裂肌中IGF1R、IGFBP3的表达动态变化。结果:治疗后2 d、3 d、7 d、14 d模型组IGF1R的表达高于空白组(P0.05);治疗后1 d、2 d电针委中组IGF1R的表达高于模型组(P0.05)。治疗后7 d、14 d模型组IGFBP3表达高于空白组;治疗后2 d、14 d电针委中组IGFBP3表达低于模型组。结论:电针委中穴可在早期增加IGF1R的表达,并下调IGFBP3的表达,促进多裂肌损伤后的修复。     

针刺会阳穴为主治疗慢性前列腺炎30例

目的：探讨会阳穴在治疗慢性前列腺炎方面的临床应用价值。方法：以会阳穴为主治疗30例服中药或西药疗效不显的慢性前列腺炎患者，观察其临床症状及针刺前后疗效。结果：30例患者自觉症状及前列腺液检查有明显改善，有效率为97％，结论：针刺会阳穴为配合相关穴位的方法对慢性前列腺炎有明显的疗效。