Measurements of Dento-occlusal Growth and Development in Children and Young Adults with Normal Occlusion

A study to measure the dento-occlusal growthand development in 639 children and young adultswith normal occlusion was carried out in Chengduarea, with an age between 7-25 years. The normal values of length and width indifferent parts (3-3; 4-4; 6-6) of the upper and     

Relationship between the Abnormal Expression of FasL on Human First Trimester Trophoblast and Spontaneous Abortion

Spontaneous abortion(SA) is a very commondisease in clinical practice.Except the known causessuch as anatomy,chromosome and endocrine etiolo-gies,there are almost5 0 % SA patients withoutdef-inite causes,which make the treatmentdifficult.Re-centstudies showed thatthe disorderof immune reg-ulation between mother and fetus played a significantrole in SA.Since the trophoblastis the directmater-nal- fetal interface,it becomes the research focus onthe immune regulation at present.Our study wasai…     

Prospective Comparative Study of Human Vas Occlusion with Chinese and Netherlandish Medical Materials

ＰｒｏｓｐｅｃｔｉｖｅＣｏｍｐａｒａｔｉｖｅＳｔｕｄｙｏｆＨｕｍａｎＶａｓＯｃｃｌｕｓｉｏｎｗｉｔｈＣｈｉｎｅｓｅａｎｄＮｅｔｈｅｒｌａｎｄｉｓｈＭｅｄｉｃａｌＭａｔｅｒｉａｌｓＨｕａｎｇＭｉｎｇ－ｋｏｎｇ；(黄明孔）ＹｕＺｈｉ－ｃａｏ；（余智超）（?..     

Establishment of the Normal Human Fibroblast Cell Line and a Study of Its Biological Characteristics

The normal human fibroblast cell line(NHF8)derived fromnormal adult foreskin was passaged successfully in vitro for more than400 d.The cells,morphologically fibroblast-like,were grown in the cellculture medium NO.I with 15% newborn calf serum and weresubcultured by trypsinization at 1:2 split ratio.The cell line had a logphase doubling time of 26h and its growth curve appeared in“s”shape.The mode of the chromosomes of the cell line was 46 and itsfrequency of sister-chromatid exchange(SCE),induced by UVirradiation or not,was 0.143 per chromosome and 0.144 perchromosome respectively.The level of UV-induced unscheduled DNAsyntheses(UDS)was also normal.The results demonstrate that thecell line is normal human diploid fibroblast cell line with normalfunction of excision repair of DNA damage and can be used as controlcells in many studies.     

Expression of Resistin Protein in Normal Human Subcutaneous Adipose Tissue and Pregnant Women Subcutaneous Adipose Tissue and Placenta

Resistinisanovelpolypeptidehormoneintheadiposetissue,whichcharacterizedbyacysteine richmotif(CX12CX8CXCX3CX10CXCXCX9CC).Resistinismainlyexpressedinthewhiteadiposetissueandweakinthebrownadiposetissue.Re sistinlinksobesitytodiabetes[1,2].Serumresistinlevelsismarkedlyincreasedinob/obanddb/dbmouse[1].Thiazolidinedionescanobviouslyreduceresistinexpressioninmouse.Duringthepregnan cy,pregnantwomenhavephysiologicalinsulinre sistance,decreaseglucosetoleranceandinsulinsensitivityandareeasytoget…     

World Medical Association Declaration of HelsinkiE thical Principles for Medical Research Involving Human Subjects

Ａｄｏｐｔｅｄｂｙｔｈｅ 18ｔｈＷＭＡＧｅｎｅｒａｌＡｓｓｅｍｂｌｙ，Ｈｅｌｓｉｎｋｉ，Ｆｉｎｌａｎｄ，Ｊｕｎｅ 196 4；ａｍｅｎｄｅｄｂｙｔｈｅ 2 9ｔｈＷＭＡＧｅｎ ｅｒａｌＡｓｓｅｍｂｌｙ，Ｔｏｋｙｏ，Ｊａｐａｎ，Ｏｃｔｏｂｅｒ 1975；35ｔｈＷＭＡＧｅｎｅｒａｌＡｓｓｅｍｂｌｙ，Ｖｅｎｉｃｅ，Ｉｔａｌｙ，Ｏｃｔｏｂｅｒ 1983；4 1ｓｔＷＭＡＧｅｎｅｒａｌＡｓｓｅｍｂｌｙ，ＨｏｎｇＫｏｎｇ，Ｓｅｐｔｅｍｂｅｒ 1989；4 8ｔｈＷＭＡＧｅｎｅｒａｌＡｓｓｅｍｂｌｙ，ＳｏｍｅｒｓｅｔＷｅｓｔ，Ｒｅｐｕｂｌｉ…     

Localization of Secretory Component in Normal Human Liver Tissue.

The secretory component(SC)whichlocalized in the epithelial ceils of bile ductsand interlobular bile ductules of normal humanliver was confirmed by the indirectimmunofluorescence technique usingFITC-labelled rabbit IgG and rabbit anti-SC     

The Structure and Early Development of Bacterial Plaque on occlusal Surface of Human Teeth

The authors presented here a report of the studyof the basic structure and early development ofnatural human occlusal plaques. 16 extractedhuman teeth were used to make histologicalsections and were observed under optical, transmis-     

The Expression and Change of the β3 Integrin Subunit and Fibronectin in Normal Human Oviductal Tissue and Tubal Ectopic Pregnant Tissue

Objective To investigate the expression and change of the B3 integrin subunit and fibronectin in normal human oviductal t‘issue during various phases of the menstrual cycle and tubal ectopic pregnant tissue Methods Samples of normal ( n=29 ) and pregnant fallopian tube ( n=22 ) tissues were obtained from women who had normal cycle and history of normal pregnancy. Normal oviductal tissue samples were divided into 4 groups based on their menstrual cycle. Both expression and distribution of the B3 subunit and fibronectin were determined with the immunohistochemical method and the image analysis. Results The B3 subunit was expressed in the cytoplasm of ciliated cells. The expression level of the B3 subunit was higher after ovulation than that before ovulation in isthmus epithelium (P ＜0.001), and declined significantly after ovulation in ampullae epithelium (P ＜0.001). In umbrella epithelium within 4 days after ovulation, the expression level of the B3 subunit was observed at rather higher level among other phases (P ＜0.001). The ciliated and secretory cells of the epithelium except for where the pregnancy occurred in tubal pregnancy expressed the subunit, and no significant relationship was found between the normal tubal tissue of the secretory phase and tubal ectopic pregnant tissue (P＞0.05). Fibronectin was expressed in the basementmembrane of human oviductal epithelium and matrix. The expression level of fibronectin was higher in the hyperplastic phase than that in the secretory one (P＜0.001). And it was lower in normal tubal tissue of the secretory, phase than that in tubal ectopic pregnant tissue (P ＜0.001). Conclusion The B3 integrin subunit was expressed in the ciliated cells of human oviductal epithelium, and fibronectin was expressed in the basement membrane of human oviductal epithelium and matrix. Their expression and change in oviductal tissue is based on different phases of menstrual cycle. The B3 subunit could not related to the occurrence of tubal ectopic pregnancy. Fibronectin could be the potential molecular basis for the tubal ectopic pregnancy.     

Fibrous Structure of Connective Tissue of Normal Human Lamina Cribrosa.

Fibrous components and structural morphology of the connective tissue of the lamina cribrosa obtained from 35 normal human autopsy eyes were examined by histochemical staining, transmission electron microscopic and computer-