Adenoid cystic carcinoma of the nasal cavity: a case report

Adenoid cystic carcinoma (ACC) is the most common malignant tumor of the minor salivary glands. The sinonasal tract is a common site of ACC occurrence, second only to the oral cavity. Of all cases of sinonasal ACC, a minority (22 to 35%) arise in the nasal cavity. Three histologic patterns of ACC have been described: cribriform, tubular, and solid. Compared with the cribriform and tubular forms, predominantly solid-type ACCs have been associated with higher rates of perineural invasion, higher S-phase fractions, and a higher incidence of aneuploidy. The histologic differentiation of solid-pattern ACC from other sinonasal malignancies typically requires the identification of one or both of the other ACC patterns in the same specimen. We present the case of a 39-year-old man with solid-pattern ACC arising in the nasal cavity. The tumor was resected endoscopically. We also discuss the relevant literature regarding the histologic diagnosis, prognosis, and treatment options for solid-pattern ACC.     

Adenoid cystic carcinoma of nasal cavity - a case report

A 38 year old male patient presented with pain and swelling on left side of nose with mass in left nostril. The other symptoms were nasal obstruction, epistaxisc from left nostril and epiphora from left eye. CT scan showed a mass arising from lateral wall of nose on left side eroding anterior part of medial wall of maxillary sinus. The tumor was excised with wide margin through a lateral rhinotomy approach under general anaesthesia. In histopathologieal examination it was found to be cribriform type of Adenoid Cystic Carcinoma. This case is reported here for its rarit.     

Paraganglioma of the nasal cavity: a case report

We describe the case of a 72-year-old woman presenting with a 1-year history of recurrent epistaxis and unilateral progressive nasal obstruction with associated rhinolalia resulting from the presence of a tumor mass occupying two-thirds of the right nasal cavity. Histopathologically, neoplastic cells or "chief cells" were arranged in well-defined nests, which had the classic alveolar or so-called "zellballen" pattern. Immunohistochemical studies highlighted the presence of S-100 protein-positive sustentacular cells located at the periphery of the clusters of chief cells. The chief cells showed a diffuse and intense positivity for neuron-specific enolase and synaptophysin. A diagnosis of paraganglioma was made. The lesion was excised completely and the patient did not develop recurrences or distant metastases after 8 months of follow-up. Paragangliomas arising in the nasal cavity and paranasal sinuses are extremely rare tumors. We report on the clinical, histopathological and immunohistochemical findings of our case and review the cases previously described in the literature.     

Leishmaniasis of the nasal cavity: a case report

Establishing diagnosis of a granulomatous lesion of the nose is often difficult. Here we report a case of granulomatous lesion of the nose caused by Leishmania--an unlikely cause in the UK. The diagnosis and management of the case is discussed here.     

鼻腔上皮-肌上皮癌1例报告并文献复习

目的:探讨鼻腔上皮-肌上皮癌的病理学特点、诊断、治疗及预后。方法:对1例鼻腔上皮-肌上皮癌进行分析,光镜观察和免疫组织化学检查,并进行文献复习。结果:临床表现不具备特征性,诊断只能依靠病理检查。肿瘤主要由肌上皮细胞和腺上皮细胞等组成,免疫组织化学检测CK-L、CK-P、S-100、α-平滑肌肌动蛋白等表达阳性。结论:鼻腔上皮-肌上皮癌是一种罕见肿瘤,以手术治疗为主,有复发和远处转移的潜能。     

Extramedullary plasmocytoma of the nasal cavity: a case report

PURPOSE OF STUDY: To establish a diagnosis and therapeutic management in patients with extramedullar plasmocytomas. METHOD: There is no consensus concerning extramedullar plasmocytoma treatment. One patient with a nasal cavity tumor location and a review of literature are reported. RESULTS: Extramedullar plasmocytoma is a rare tumor that occurs most frequently in the upper respiratory tract. The most common location is the nasal cavity. Diagnosis can only be made after histological and immunohistochemical examinations. Localized tumors are treated by radiation therapy, combined or not with surgery. Disseminated diseases are treated by chemotherapy. CONCLUSION: Diagnosis can only be confirmed after the exclusion of a systemic disease (multiple myeloma).     

Complex odontoma of the nasal cavity: a case report

We describe the case of a 76-year-old man who presented with symptoms of chronic nasal obstruction and recurrent sinusitis of many years' duration. The patient's history and radiographic findings established a diagnosis of a complex odontoma of the nasal cavity. The mass was surgically excised, and the diagnosis was confirmed by histopathology. The occurrence of an odontoma in the nasal cavity is extremely rare.     

Nodular fasciitis of the nasal cavity: a case report

Nodular fasciitis is an uncommon tumor-like fibroblastic proliferation of the head and neck that is difficult to differentiate from its more malignant counterparts. Despite modern advances, making this distinction is challenging because the clinical presentation is nonspecific and the histologic and radiologic features are variable. Once nodular fasciitis is diagnosed, the primary treatment is conservative resection and observation. We describe a case of nodular fasciitis of the nasal cavity in a 43-year-old woman. To the best of our knowledge, this is only the second reported case of nodular fasciitis arising in the nasal cavity, and the first such case in an adult.     

Malignant oncocytoma of the nasal cavity: a case report.

Malignant oncocytoma is a rare clinical entity and is most commonly seen in the salivary glands. Its occurrence in the nasal cavity is extremely rare, and only 4 such cases have been reported in the literature. The authors report one such case in a 60-year-old woman, which presented as a slow-growing nasal mass arising from the nasal septum, with no lymph node metastasis, which was successfully managed by a combined modality of treatment-surgery followed by radiation therapy. The relevant literature has been reviewed. The case is discussed as a possible differential diagnosis for a mass in the nose.     

Hemangiopericytoma like tumor of the nasal cavity: a case report

Sinonasal hemangiopericytoma originates from vascular pericytes. It may arise in any part of the body but it is an uncommon vascular tumor in the nose. It can show benign or malignant histologic features. Sinonasal hemangiopericytoma like tumor is important as it is recognized as a special variant of hemangiopericytoma. In this article, we present a 65-year-old male patient with hemangiopericytoma like tumor of the nasal cavity.     

Verrucous carcinoma of the nasal septum

A case of verrucous carcinoma of the nose is presented. Initially two pathologists described the lesion as benign. The tumour was excised with free margins through a lateral rhinotomy, with a successful outcome. The literature on the topic has been reviewed. Deep wide-based biopsy should always be considered if such a lesion is not to be missed on the first consultation. Surgery in resectable lesions offers the best chance of survival in verrucous carcinoma of the nose.     

Verrucous carcinoma of the oral cavity

The clinical course and morphologic (light and ultrastructural) characteristics of a case of verrucous carcinoma of the lower gingival mucosa are presented. Clinical course of the patient was unfavorable following surgery (supposedly incomplete) and radiotherapy (6,000 R) of the tumor. The therapeutic factors that may influence an unfavourable prognosis are commented upon, especially in regard to a slow-growing neoplasm with a generally good course.     

鼻腔尤文肉瘤一例

患者女,40岁.因右侧鼻塞伴右眼流泪2个月于2006年9月8日入院.无涕中带血、视力模糊、头痛、面部麻木、牙齿疼痛及嗅觉减退症状.体检:鼻外形无明显畸形,鼻中隔稍偏左,右侧鼻腔总鼻道及下鼻道充满红色新生物,中鼻道少量黏性分泌物,左侧下鼻甲、中鼻道未见明显异常.鼻窦CT示右侧鼻腔可见大小约2.8 cm×2.5 cm的肿块,右侧下鼻甲及卜颌窦内侧壁骨质部分吸收(图1).     

鼻腔原发性粒细胞肉瘤一例

患者女,57岁,2007年4月因双侧鼻塞反复发作1年余入院.查体:鼻中隔左偏,双侧下鼻甲充血、肿胀,双侧中鼻道未见息肉样物及分泌物.行鼻窦CT检查示:左侧上颌窦、双侧筛窦炎症,双侧下鼻道见软组织密度影,阻塞右侧后鼻孔(图1a).入院诊断:"慢性鼻-鼻窦炎(Ⅰ型2期)、慢性肥厚性鼻炎".     

鼻腔多形性腺瘤恶性变一例

患者男，69岁。以右侧鼻塞5年，鼻旁隆起及鼻外肿块7个月于2006年2月23日入院。患者5年前因右侧鼻塞就诊于当地医院，表面麻醉下经前鼻孔行鼻腔肿物摘除，病理报告为鼻腔混合瘤。术后鼻腔通气较好，未曾复诊。半年前开始出现渐进性鼻塞及少量涕中带血，右侧鼻前孔有肿物突出伴右侧鼻背隆起畸形。4个月前在当地医院CT检查示右鼻腔前部有光滑肿物，骨质完整，未行治疗。近1个月来，     

Giant cell tumor of the nasal cavity: case report

Soft tissue giant cell tumor of low malignant potential is a rare tumor located in superficial and deep soft tissue. Tumors with osteoclast-like giant cells have been reported in various sites as breast, salivary glands, lung, kidney and pancreas. These tumors are composed of evenly spaced multinucleated giant cells in a background of mononuclear component composed of round, oval or spindled cells. No atypia or significant mitotic activity is encountered. Immunohistochemical stains for TRAP, smooth muscle actin, desmin and cytokeratins are of great value for diagnosis. Nasal cavity represents a very unusual location for this type of tumors; soft tissue tumors must be included in the differential diagnosis of nasal obstruction. Due to the possibility of local recurrence, clinical follow-up is recommended.